ERG (ETS transcription factor ERG) - Rat Genome Database

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Gene: ERG (ETS transcription factor ERG) Chlorocebus sabaeus
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Symbol: ERG
Name: ETS transcription factor ERG
RGD ID: 18553150
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN cell differentiation (inferred); positive regulation of transcription by RNA polymerase II (inferred); regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); epilepsy (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ERG, ETS transcription factor; transcriptional regulator ERG
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,327,088 - 82,611,341 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,326,767 - 82,447,228 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ERG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,327,088 - 82,611,341 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,326,767 - 82,447,228 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ERG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382138,367,261 - 38,661,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2138,380,027 - 38,661,780 (-)EnsemblGRCh38hg38GRCh38
GRCh372139,739,183 - 40,033,707 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,675,671 - 38,955,488 (-)NCBINCBI36Build 36hg18NCBI36
Build 342138,675,670 - 38,792,267NCBI
Celera2124,949,807 - 25,231,400 (-)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2125,208,970 - 25,503,512 (-)NCBIHuRef
CHM1_12139,299,733 - 39,594,417 (-)NCBICHM1_1
T2T-CHM13v2.02136,750,675 - 37,045,540 (-)NCBIT2T-CHM13v2.0
Erg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,160,028 - 95,387,452 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,160,028 - 95,387,452 (-)EnsemblGRCm39 Ensembl
GRCm381695,359,169 - 95,586,600 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,359,169 - 95,586,593 (-)EnsemblGRCm38mm10GRCm38
MGSCv371695,581,811 - 95,751,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361695,469,002 - 95,639,163 (-)NCBIMGSCv36mm8
Celera1696,438,595 - 96,608,910 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.04NCBI
Erg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,148,149 - 48,370,472 (-)NCBIGRCr8
mRatBN7.21134,678,614 - 34,900,951 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1134,678,618 - 34,845,871 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,337,399 - 43,439,463 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,008,778 - 36,110,844 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,154,256 - 35,256,482 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01135,645,317 - 35,749,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,646,116 - 35,749,594 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,231,276 - 39,336,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,655,563 - 35,760,055 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,711,805 - 35,816,365 (-)NCBI
Celera1133,675,593 - 33,777,118 (+)NCBICelera
Cytogenetic Map11q11NCBI
Erg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,369,641 - 37,542,751 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,372,471 - 37,613,674 (-)NCBIChiLan1.0ChiLan1.0
ERG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22234,488,819 - 34,768,247 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12129,346,968 - 29,624,485 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02124,737,829 - 25,016,378 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12138,087,333 - 38,366,637 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,087,339 - 38,281,403 (-)Ensemblpanpan1.1panPan2
ERG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13133,456,902 - 33,562,704 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3133,497,209 - 33,515,272 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3132,529,920 - 32,716,050 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03132,767,321 - 32,953,675 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3132,766,017 - 33,032,122 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13132,642,385 - 32,828,520 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03132,646,486 - 32,832,235 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03133,135,132 - 33,321,177 (-)NCBIUU_Cfam_GSD_1.0
Erg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497132,843,364 - 33,008,541 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365004,459,275 - 4,624,432 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365004,459,298 - 4,623,290 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,000,995 - 202,301,368 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113201,999,237 - 202,302,572 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213212,086,250 - 212,156,873 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Erg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474525,294,832 - 25,459,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474525,239,356 - 25,457,533 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000006518   ⟹   ENSCSAP00000004720
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl282,326,767 - 82,447,228 (-)Ensembl
RefSeq Acc Id: XM_007968079   ⟹   XP_007966270
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1282,327,088 - 82,611,341 (-)NCBI
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,456 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968098   ⟹   XP_007966289
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1282,327,088 - 82,448,484 (-)NCBI
Vero_WHO_p1.0NW_02366605410,177,651 - 10,300,340 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007968105   ⟹   XP_007966296
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1282,327,090 - 82,611,338 (-)NCBI
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,452 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037984801   ⟹   XP_037840729
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605410,177,651 - 10,300,337 (-)NCBI
RefSeq Acc Id: XM_037984802   ⟹   XP_037840730
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366605410,177,651 - 10,463,460 (-)NCBI
RefSeq Acc Id: XP_007966270   ⟸   XM_007968079
- Peptide Label: isoform X1
RefSeq Acc Id: XP_007966289   ⟸   XM_007968098
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R7Y1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007966296   ⟸   XM_007968105
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCSAP00000004720   ⟸   ENSCSAT00000006518
RefSeq Acc Id: XP_037840730   ⟸   XM_037984802
- Peptide Label: isoform X5
RefSeq Acc Id: XP_037840729   ⟸   XM_037984801
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008463 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006518.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  Pointed_dom UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene ERG ENTREZGENE
PANTHER PTHR11849 UniProtKB/TrEMBL
  TRANSCRIPTIONAL REGULATOR ERG UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
UniProt A0A0D9R7Y1 ENTREZGENE, UniProtKB/TrEMBL