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Gene: ERG (ETS transcription factor ERG) Homo sapiens
Symbol: ERG
Name: ETS transcription factor ERG
RGD ID: 1348469
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to ribonucleoprotein complex. Implicated in myeloid leukemia. Biomarker of pulmonary venoocclusive disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ERG, ETS transcription factor; erg-3; erythroblast transformation-specific transcription factor ERG variant 10; ets-related; p55; TMPRSS2-ERG prostate cancer specific; TMPRSS2/ERG fusion; transcriptional regulator ERG; transcriptional regulator ERG (transforming protein ERG); transforming protein ERG; v-ets avian erythroblastosis virus E26 oncogene homolog; v-ets avian erythroblastosis virus E26 oncogene related; v-ets erythroblastosis virus E26 oncogene homolog; v-ets erythroblastosis virus E26 oncogene like; v-ets erythroblastosis virus e26 oncogene like (avian)
Mus musculus (house mouse) : Erg (ETS transcription factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Erg (ETS transcription factor ERG)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erg (ETS transcription factor ERG)
Pan paniscus (bonobo/pygmy chimpanzee) : ERG (ETS transcription factor ERG)
Canis lupus familiaris (dog) : ERG (ETS transcription factor ERG)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erg (ETS transcription factor ERG)
Sus scrofa (pig) : ERG (ETS transcription factor ERG)
Chlorocebus sabaeus (African green monkey) : ERG (ETS transcription factor ERG)
Heterocephalus glaber (naked mole-rat) : Erg (ETS transcription factor ERG)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2138,380,027 - 38,661,780 (-)EnsemblGRCh38hg38GRCh38
GRCh382138,367,261 - 38,661,783 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372139,739,183 - 40,033,704 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362138,675,671 - 38,955,488 (-)NCBINCBI36hg18NCBI36
Build 342138,675,670 - 38,792,267NCBI
Celera2124,949,807 - 25,231,400 (-)NCBI
Cytogenetic Map21q22.2NCBI
HuRef2125,208,970 - 25,503,512 (-)NCBIHuRef
CHM1_12139,299,733 - 39,594,417 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ERG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348469
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.