Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of SNX4 mRNA | CTD | PMID:23649840 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SNX4 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SNX4 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Snx4 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of SNX4 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Snx4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SNX4 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | ISO | Snx4 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of SNX4 mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Snx4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SNX4 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SNX4 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Snx4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SNX4 mRNA | CTD | PMID:21570461 | 2-hydroxypropanoic acid | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SNX4 mRNA | CTD | PMID:30851411 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of SNX4 mRNA | CTD | PMID:19162173 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SNX4 mRNA | CTD | PMID:36041667 | acrolein | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SNX4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SNX4 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | SNX4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SNX4 intron | CTD | PMID:30157460 | alpha-hexachlorocyclohexane | increases expression | EXP | | 6480464 | alpha-hexachlorocyclohexane results in increased expression of SNX4 mRNA | CTD | PMID:17785943 | alpha-pinene | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SNX4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of SNX4 mRNA | CTD | PMID:32699268 | atrazine | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of SNX4 mRNA | CTD | PMID:22378314 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | increases expression | ISO | Snx4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SNX4 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | Snx4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of SNX4 intron | CTD | PMID:27901495 | bisphenol A | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SNX4 mRNA | CTD | PMID:25047013 and PMID:29275510 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SNX4 mRNA | CTD | PMID:36041667 | bisphenol A | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SNX4 mRNA | CTD | PMID:33221593 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SNX4 mRNA | CTD | PMID:36041667 | carbon nanotube | increases expression | ISO | Snx4 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of SNX4 mRNA | CTD | PMID:25554681 | carnosic acid | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | salvin results in decreased expression of SNX4 protein | CTD | PMID:35926579 | CGP 52608 | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SNX4 gene] | CTD | PMID:28238834 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA | CTD | PMID:33854195 | cobalt dichloride | increases expression | ISO | SNX4 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SNX4 mRNA | CTD | PMID:19376846 | copper(II) sulfate | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SNX4 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SNX4 mRNA | CTD | PMID:25562108 | dicrotophos | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SNX4 mRNA | CTD | PMID:28302478 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SNX4 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of SNX4 mRNA | CTD | PMID:35436446 | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of SNX4 mRNA | CTD | PMID:24793618 | folic acid | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SNX4 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SNX4 mRNA | CTD | PMID:20655997 | FR900359 | decreases phosphorylation | ISO | SNX4 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of SNX4 protein | CTD | PMID:37730182 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA | CTD | PMID:33854195 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA | CTD | PMID:33854195 | ivermectin | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SNX4 protein | CTD | PMID:32959892 | lead diacetate | increases expression | ISO | Snx4 (Mus musculus) | 6480464 | lead acetate results in increased expression of SNX4 mRNA | CTD | PMID:21829687 | lipopolysaccharide | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of SNX4 mRNA | CTD | PMID:35877022 | N(4)-hydroxycytidine | decreases expression | ISO | Snx4 (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of SNX4 mRNA | CTD | PMID:37748715 | ozone | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of SNX4 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Snx4 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of SNX4 mRNA | CTD | PMID:34911549 | paracetamol | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SNX4 mRNA | CTD | PMID:29067470 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SNX4 mRNA | CTD | PMID:33387578 | perfluorohexanesulfonic acid | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of SNX4 mRNA | CTD | PMID:25812627 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SNX4 mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | increases expression | ISO | SNX4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of SNX4 mRNA | CTD | PMID:25812627 | perfluorooctanoic acid | increases expression | ISO | SNX4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of SNX4 mRNA | CTD | PMID:25812627 | potassium chromate | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SNX4 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of SNX4 mRNA | CTD | PMID:22079256 | rac-lactic acid | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SNX4 mRNA | CTD | PMID:30851411 | resveratrol | increases expression | ISO | Snx4 (Mus musculus) | 6480464 | resveratrol results in increased expression of SNX4 protein | CTD | PMID:25505154 | resveratrol | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SNX4 mRNA | CTD | PMID:23557933 | sodium arsenite | affects methylation | ISO | SNX4 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of SNX4 gene | CTD | PMID:28589171 | sunitinib | increases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SNX4 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Snx4 (Mus musculus) | 6480464 | Tamoxifen affects the expression of SNX4 mRNA | CTD | PMID:17555576 | tert-butyl hydroperoxide | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of SNX4 mRNA | CTD | PMID:15336504 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA | CTD | PMID:33854195 | thimerosal | increases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Thimerosal results in increased expression of SNX4 mRNA | CTD | PMID:27188386 | trovafloxacin | multiple interactions | ISO | SNX4 (Homo sapiens) | 6480464 | [trovafloxacin co-treated with TNF protein] results in decreased expression of SNX4 mRNA | CTD | PMID:33609687 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SNX4 mRNA | CTD | PMID:19015723 | vincristine | decreases expression | ISO | SNX4 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of SNX4 mRNA | CTD | PMID:23649840 | |