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Gene: Cpox (coproporphyrinogen oxidase) Rattus norvegicus
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Symbol: Cpox
Name: coproporphyrinogen oxidase
Description: Exhibits coproporphyrinogen oxidase activity and identical protein binding activity. Involved in several processes, including protoporphyrinogen IX biosynthetic process; response to lead ion; and response to methylmercury. Localizes to the mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; heme biosynthetic pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coprogen oxidase; coproporphyrinogen-III oxidase, mitochondrial; coproporphyrinogenase; COX; LOC304024; MGC124847; oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Orthologs:
Homo sapiens (human) : CPOX (coproporphyrinogen oxidase)  HGNC  Alliance
Mus musculus (house mouse) : Cpox (coproporphyrinogen oxidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpox (coproporphyrinogen oxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : CPOX (coproporphyrinogen oxidase)
Canis lupus familiaris (dog) : CPOX (coproporphyrinogen oxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpox (coproporphyrinogen oxidase)
Sus scrofa (pig) : CPOX (coproporphyrinogen oxidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01144,039,665 - 44,049,648 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,039,669 - 44,049,648 (-)Ensembl
Rnor_5.01147,229,581 - 47,239,564 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41142,748,703 - 42,758,686 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11142,807,556 - 42,935,211 (-)NCBI
Celera1141,735,836 - 41,745,819 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cpox
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311817
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.