Cd200 (Cd200 molecule) - Rat Genome Database

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Gene: Cd200 (Cd200 molecule) Rattus norvegicus
Analyze
Symbol: Cd200
Name: Cd200 molecule
RGD ID: 3104
Description: Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including negative regulation of interleukin-6 production; negative regulation of mononuclear cell migration; and negative regulation of neuroinflammatory response. Located in cell surface; neuron projection; and neuronal cell body. Orthologous to human CD200 (CD200 molecule); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: antigen identified by monoclonal antibody MRC OX-2; Cd200 antigen; cell surface protein (thymocyte antigen identified by monoclonal antibody MRC-OX2); cell surface protein (thymocyte, antigen identified by monoclonal antibody MRC-OX2); Cspmo2; MGC108657; Mox2; MRC OX-2 antigen; MRCOX2; OX-2 membrane glycoprotein
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,916,200 - 68,943,570 (+)NCBIGRCr8
mRatBN7.21155,410,166 - 55,437,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,410,196 - 55,501,648 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,224,976 - 64,251,219 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01156,886,834 - 56,913,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01155,959,450 - 55,986,668 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01160,371,617 - 60,398,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,371,684 - 60,403,196 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01164,474,114 - 64,501,029 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,946,504 - 56,974,256 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,004,092 - 57,031,845 (+)NCBI
Celera1154,978,287 - 55,004,105 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aconitine  (EXP)
alachlor  (EXP)
aldrin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
atrazine  (EXP)
Azoxymethane  (ISO)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chrysene  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
ionomycin  (ISO)
ketoconazole  (ISO)
lead(0)  (ISO)
melatonin  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (EXP,ISO)
nickel subsulfide  (EXP)
nickel sulfate  (EXP,ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
poly(I:C)  (ISO)
potassium chromate  (ISO)
progesterone  (EXP,ISO)
pyrrolidine dithiocarbamate  (ISO)
raloxifene  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tremolite asbestos  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (IBA,IEA,ISO)
cell body  (IEA,ISO)
cell surface  (IBA,IDA,IEA,ISO)
membrane  (IEA)
neuron projection  (IDA)
neuronal cell body  (IBA,IDA,IEA,ISO)
plasma membrane  (IEA)
postsynaptic density  (ISO)
presynaptic active zone  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitional expression of OX-2 and GAP-43 glycoproteins in developing rat cochlear nerve fibers. Bartolome MV, etal., Histol Histopathol 2002 Jan;17(1):83-95.
2. MRC OX-2 antigen: a lymphoid/neuronal membrane glycoprotein with a structure like a single immunoglobulin light chain. Clark MJ, etal., EMBO J 1985 Jan;4(1):113-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing. Meuth SG, etal., J Neuroimmunol. 2008 Feb;194(1-2):62-9. doi: 10.1016/j.jneuroim.2007.11.013.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages. Preston S, etal., Eur J Immunol. 1997 Aug;27(8):1911-8. doi: 10.1002/eji.1830270814.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. The proteins encoded by rice grassy stunt virus RNA5 and RNA6 are only distantly related to the corresponding proteins of other members of the genus Tenuivirus. Toriyama S, etal., J Gen Virol. 1997 Sep;78 ( Pt 9):2355-63. doi: 10.1099/0022-1317-78-9-2355.
12. Localisation of the MRC OX-2 glycoprotein on the surfaces of neurones. Webb M and Barclay AN, J Neurochem. 1984 Oct;43(4):1061-7.
13. Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Wright GJ, etal., Immunity 2000 Aug;13(2):233-42.
Additional References at PubMed
PMID:11099416   PMID:11260322   PMID:12477932   PMID:15512981   PMID:17726108   PMID:18296487   PMID:19151626   PMID:21453758   PMID:22053982   PMID:22342946   PMID:22684568   PMID:25519046  
PMID:26670206   PMID:27108386   PMID:27830533   PMID:28664397   PMID:29101312   PMID:29339155   PMID:29476059   PMID:30006626   PMID:32473633   PMID:32664639   PMID:36591265   PMID:37971567  
PMID:38237226  


Genomics

Comparative Map Data
Cd200
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81168,916,200 - 68,943,570 (+)NCBIGRCr8
mRatBN7.21155,410,166 - 55,437,527 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,410,196 - 55,501,648 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1164,224,976 - 64,251,219 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01156,886,834 - 56,913,080 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01155,959,450 - 55,986,668 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01160,371,617 - 60,398,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1160,371,684 - 60,403,196 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01164,474,114 - 64,501,029 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,946,504 - 56,974,256 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,004,092 - 57,031,845 (+)NCBI
Celera1154,978,287 - 55,004,105 (+)NCBICelera
Cytogenetic Map11q21NCBI
CD200
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383112,332,573 - 112,362,812 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3112,332,235 - 112,363,181 (+)EnsemblGRCh38hg38GRCh38
GRCh373112,051,420 - 112,081,659 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363113,534,606 - 113,564,349 (+)NCBINCBI36Build 36hg18NCBI36
Celera3110,460,648 - 110,490,361 (+)NCBICelera
Cytogenetic Map3q13.2NCBI
HuRef3109,436,001 - 109,465,715 (+)NCBIHuRef
CHM1_13112,015,971 - 112,045,683 (+)NCBICHM1_1
T2T-CHM13v2.03115,053,635 - 115,083,861 (+)NCBIT2T-CHM13v2.0
Cd200
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391645,202,474 - 45,229,419 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1645,202,498 - 45,229,416 (-)EnsemblGRCm39 Ensembl
GRCm381645,382,111 - 45,409,060 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1645,382,135 - 45,409,053 (-)EnsemblGRCm38mm10GRCm38
MGSCv371645,382,248 - 45,409,166 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361645,301,440 - 45,328,223 (-)NCBIMGSCv36mm8
Celera1645,782,157 - 45,809,002 (-)NCBICelera
Cytogenetic Map16B5NCBI
cM Map1629.53NCBI
CD200
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22110,334,631 - 110,365,077 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13110,339,408 - 110,369,857 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03109,481,067 - 109,511,261 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13116,404,606 - 116,434,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3116,404,728 - 116,434,363 (+)Ensemblpanpan1.1panPan2
CD200
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13316,872,849 - 16,892,161 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3316,873,048 - 16,890,954 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3316,975,655 - 17,001,572 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03317,116,263 - 17,142,263 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3317,116,357 - 17,136,128 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13316,921,533 - 16,947,516 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03316,968,748 - 16,994,765 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03317,517,917 - 17,543,967 (+)NCBIUU_Cfam_GSD_1.0
Cd200
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602137,487,118 - 137,513,588 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,262 - 35,197 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,337 - 33,954 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CD200
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13147,465,863 - 147,486,141 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113147,465,858 - 147,485,818 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213157,173,775 - 157,193,532 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CD200
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12268,429,544 - 68,459,711 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2268,426,459 - 68,459,616 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604198,009,245 - 98,038,967 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd200
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473136,223,673 - 36,251,542 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473136,224,360 - 36,251,656 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd200
141 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:298
Count of miRNA genes:206
Interacting mature miRNAs:229
Transcripts:ENSRNOT00000058453
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat

Markers in Region
D11Wox3  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81168,943,076 - 68,943,260 (+)Marker Load Pipeline
mRatBN7.21155,437,033 - 55,437,217 (+)MAPPERmRatBN7.2
Rnor_6.01160,397,957 - 60,398,140NCBIRnor6.0
Rnor_5.01164,500,538 - 64,500,721UniSTSRnor5.0
RGSC_v3.41156,973,743 - 56,973,927RGDRGSC3.4
RGSC_v3.41156,973,744 - 56,973,927UniSTSRGSC3.4
RGSC_v3.11157,031,332 - 57,031,516RGD
RH 2.0 Map11223.6RGD
Cytogenetic Map11q21-q22UniSTS
D11Mit6   No map positions available.
D11Arb6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21155,436,998 - 55,437,237 (+)MAPPERmRatBN7.2
Rnor_6.01160,397,922 - 60,398,160NCBIRnor6.0
Rnor_5.01164,500,503 - 64,500,741UniSTSRnor5.0
RGSC_v3.41156,973,708 - 56,973,947RGDRGSC3.4
RGSC_v3.41156,973,709 - 56,973,947UniSTSRGSC3.4
RGSC_v3.11157,031,297 - 57,031,536RGD
Cytogenetic Map11q21-q22UniSTS
AF004023  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21155,436,214 - 55,436,345 (+)MAPPERmRatBN7.2
Rnor_6.01160,397,138 - 60,397,268NCBIRnor6.0
Rnor_5.01164,499,719 - 64,499,849UniSTSRnor5.0
RGSC_v3.41156,972,925 - 56,973,055UniSTSRGSC3.4
Celera1155,003,272 - 55,003,402UniSTS
Cytogenetic Map11q21-q22UniSTS
RH133122  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21155,437,314 - 55,437,497 (+)MAPPERmRatBN7.2
Rnor_6.01160,398,238 - 60,398,420NCBIRnor6.0
Rnor_5.01164,500,819 - 64,501,001UniSTSRnor5.0
RGSC_v3.41156,974,025 - 56,974,207UniSTSRGSC3.4
Cytogenetic Map11q21-q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000058453   ⟹   ENSRNOP00000055253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1155,410,196 - 55,501,648 (+)Ensembl
Rnor_6.0 Ensembl1160,371,729 - 60,398,450 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1155,410,218 - 55,437,472 (+)Ensembl
Rnor_6.0 Ensembl1160,371,684 - 60,385,721 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093295   ⟹   ENSRNOP00000076082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1155,418,712 - 55,501,648 (+)Ensembl
Rnor_6.0 Ensembl1160,383,431 - 60,403,196 (+)Ensembl
RefSeq Acc Id: NM_031518   ⟹   NP_113706
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81168,916,315 - 68,943,568 (+)NCBI
mRatBN7.21155,410,270 - 55,437,525 (+)NCBI
Rnor_6.01160,371,729 - 60,398,448 (+)NCBI
Rnor_5.01164,474,114 - 64,501,029 (+)NCBI
RGSC_v3.41156,946,504 - 56,974,256 (+)RGD
Celera1154,978,287 - 55,004,105 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006248325   ⟹   XP_006248387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81168,916,241 - 68,943,570 (+)NCBI
mRatBN7.21155,410,180 - 55,437,527 (+)NCBI
Rnor_6.01160,371,814 - 60,398,450 (+)NCBI
Rnor_5.01164,474,114 - 64,501,029 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597873   ⟹   XP_017453362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81168,916,200 - 68,943,570 (+)NCBI
mRatBN7.21155,410,166 - 55,437,527 (+)NCBI
Rnor_6.01160,371,617 - 60,398,450 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597875   ⟹   XP_017453364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81168,928,637 - 68,943,570 (+)NCBI
mRatBN7.21155,410,166 - 55,437,527 (+)NCBI
Rnor_6.01160,371,617 - 60,398,450 (+)NCBI
Sequence:
RefSeq Acc Id: NP_113706   ⟸   NM_031518
- Peptide Label: precursor
- UniProtKB: P04218 (UniProtKB/Swiss-Prot),   A0A5D0 (UniProtKB/TrEMBL),   A6IQY8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248387   ⟸   XM_006248325
- Peptide Label: isoform X1
- UniProtKB: A0A1W2Q5Z8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453362   ⟸   XM_017597873
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017453364   ⟸   XM_017597875
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000055253   ⟸   ENSRNOT00000058453
Ensembl Acc Id: ENSRNOP00000076082   ⟸   ENSRNOT00000093295
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type   Immunoglobulin-like beta-sandwich

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P04218-F1-model_v2 AlphaFold P04218 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698139
Promoter ID:EPDNEW_R8663
Type:initiation region
Name:Cd200_1
Description:Cd200 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01160,371,671 - 60,371,731EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3104 AgrOrtholog
BioCyc Gene G2FUF-21377 BioCyc
Ensembl Genes ENSRNOG00000002141 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000058453 ENTREZGENE
  ENSRNOT00000093295 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7380792 IMAGE-MGC_LOAD
InterPro CD200 UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
  OX2G-like UniProtKB/Swiss-Prot
MGC_CLONE MGC:108657 IMAGE-MGC_LOAD
NCBI Gene 24560 ENTREZGENE
PANTHER OX-2 MEMBRANE GLYCOPROTEIN UniProtKB/Swiss-Prot
  PTHR46841:SF3 UniProtKB/Swiss-Prot
Pfam PF00047 UniProtKB/Swiss-Prot
PhenoGen Cd200 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002141 RatGTEx
SMART IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A1W2Q5Z8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5D0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0D7_RAT UniProtKB/TrEMBL
  A6IQY8 ENTREZGENE, UniProtKB/TrEMBL
  A6IQY9_RAT UniProtKB/TrEMBL
  A6IQZ0_RAT UniProtKB/TrEMBL
  OX2G_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27 Cd200  Cd200 molecule  Cd200  Cd200 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cd200  Cd200 antigen  Mox2  antigen identified by monoclonal antibody MRC OX-2  Symbol and Name updated 1299863 APPROVED
2001-07-23 Mox2  antigen identified by monoclonal antibody MRC OX-2      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED
2001-07-23 Mox2  Cell surface protein (thymocyte, antigen identified by monoclonal antibody MRC-OX2      Name withdrawn 67952 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_domains contains a Ig V domain and a Ig C domain 729268
gene_expression expressed in thymocytes, B cells, follicular dendritic cells and endothelium 729268