Sod1 (superoxide dismutase 1) - Rat Genome Database

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Gene: Sod1 (superoxide dismutase 1) Rattus norvegicus
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Symbol: Sod1
Name: superoxide dismutase 1
RGD ID: 3731
Description: Enables copper ion binding activity; protein phosphatase 2B binding activity; and superoxide dismutase activity. Involved in several processes, including cellular response to metal ion; hydrogen peroxide biosynthetic process; and removal of superoxide radicals. Located in several cellular components, including dense core granule; neuronal cell body; and peroxisome. Part of protein-containing complex. Used to study hyperthyroidism; hypothyroidism; middle cerebral artery infarction; and sciatic neuropathy. Biomarker of several diseases, including artery disease (multiple); congenital diaphragmatic hernia; metabolic dysfunction-associated steatohepatitis; middle cerebral artery infarction; and ocular hypertension. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; artery disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1); PARTICIPATES IN hypertension pathway; amyotrophic lateral sclerosis pathway; forkhead class A signaling pathway; INTERACTS WITH (+)-catechin; (+)-taxifolin; (-)-cotinine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CuZnSOD; Superoxide dimutase 1 soluble; superoxide dismutase; Superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase [Cu-Zn]
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21129,456,673 - 29,462,249 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1129,456,558 - 29,462,249 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1138,144,681 - 38,150,257 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01130,816,072 - 30,821,648 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01130,005,455 - 30,011,012 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01130,363,282 - 30,368,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1130,363,280 - 30,368,862 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01133,982,764 - 33,988,340 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,810,766 - 29,816,342 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11129,810,765 - 29,816,342 (-)NCBI
Celera1129,143,740 - 29,149,316 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model