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Gene: Sod1 (superoxide dismutase 1) Rattus norvegicus
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Symbol: Sod1
Name: superoxide dismutase 1
Description: Exhibits copper ion binding activity; protein phosphatase 2B binding activity; and superoxide dismutase activity. Involved in several processes, including cellular response to ATP; cellular response to metal ion; and hydrogen peroxide biosynthetic process. Localizes to several cellular components, including the cytoplasm; neuronal cell body; and nucleus. Predicted to colocalize with the plasma membrane. Used to study hyperthyroidism; hypothyroidism; middle cerebral artery infarction; and sciatic neuropathy. Biomarker of several diseases, including artery disease (multiple); congenital diaphragmatic hernia; cystitis; ocular hypertension; and polycystic kidney disease. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); brain disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and neurodegenerative disease (multiple). Orthologous to human SOD1 (superoxide dismutase 1); PARTICIPATES IN hypertension pathway; amyotrophic lateral sclerosis pathway; forkhead class A signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (-)-cotinine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CuZnSOD; Superoxide dimutase 1 soluble; superoxide dismutase; Superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase [Cu-Zn]
Orthologs:
Homo sapiens (human) : SOD1 (superoxide dismutase 1)  HGNC  Alliance
Mus musculus (house mouse) : Sod1 (superoxide dismutase 1, soluble)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod1 (superoxide dismutase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD1 (superoxide dismutase 1)
Canis lupus familiaris (dog) : SOD1 (superoxide dismutase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sod1 (superoxide dismutase 1)
Sus scrofa (pig) : SOD1 (superoxide dismutase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01130,363,282 - 30,368,858 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01133,982,764 - 33,988,340 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,810,766 - 29,816,342 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11129,810,765 - 29,816,342 (-)NCBI
Celera1129,143,740 - 29,149,316 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated