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Gene: Rubcn (rubicon autophagy regulator) Rattus norvegicus
Symbol: Rubcn
Name: rubicon autophagy regulator
Description: Predicted to be involved in negative regulation of autophagosome maturation; negative regulation of endocytosis; and negative regulation of phosphatidylinositol 3-kinase activity. Predicted to localize to the cytosol; endosome; and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 15. Orthologous to human RUBCN (rubicon autophagy regulator); PARTICIPATES IN autophagy pathway; INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); carbamazepine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC303885; RGD1305422; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; similar to mKIAA0226 protein
Homo sapiens (human) : RUBCN (rubicon autophagy regulator)  HGNC  Alliance
Mus musculus (house mouse) : Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rubcn (rubicon autophagy regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : RUBCN (rubicon autophagy regulator)
Canis lupus familiaris (dog) : RUBCN (rubicon autophagy regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rubcn (rubicon autophagy regulator)
Sus scrofa (pig) : RUBCN (rubicon autophagy regulator)
Chlorocebus sabaeus (African green monkey) : RUBCN (rubicon autophagy regulator)
Heterocephalus glaber (naked mole-rat) : Rubcn (rubicon autophagy regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01171,150,506 - 71,199,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,228,171 - 74,284,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,735,303 - 69,784,725 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,791,474 - 69,840,095 (+)NCBI
Celera1167,351,336 - 67,408,299 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rubcn
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305422
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.