Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Rubcn (rubicon autophagy regulator) Rattus norvegicus
Analyze
Symbol: Rubcn
Name: rubicon autophagy regulator
Description: Predicted to be involved in negative regulation of autophagosome maturation; negative regulation of endocytosis; and negative regulation of phosphatidylinositol 3-kinase activity. Predicted to localize to the cytosol; endosome; and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 15. Orthologous to human RUBCN (rubicon autophagy regulator); PARTICIPATES IN autophagy pathway; INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); carbamazepine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC303885; RGD1305422; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; similar to mKIAA0226 protein
Orthologs:
Homo sapiens (human) : RUBCN (rubicon autophagy regulator)  HGNC  Alliance
Mus musculus (house mouse) : Rubcn (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rubcn (rubicon autophagy regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : RUBCN (rubicon autophagy regulator)
Canis lupus familiaris (dog) : RUBCN (rubicon autophagy regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rubcn (rubicon autophagy regulator)
Sus scrofa (pig) : RUBCN (rubicon autophagy regulator)
Chlorocebus sabaeus (African green monkey) : RUBCN (rubicon autophagy regulator)
Heterocephalus glaber (naked mole-rat) : Rubcn (rubicon autophagy regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01171,150,506 - 71,199,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,228,171 - 74,284,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,735,303 - 69,784,725 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,791,474 - 69,840,095 (+)NCBI
Celera1167,351,336 - 67,408,299 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rubcn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305422
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.