Rubcn (rubicon autophagy regulator) - Rat Genome Database

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Gene: Rubcn (rubicon autophagy regulator) Rattus norvegicus
Analyze
Symbol: Rubcn
Name: rubicon autophagy regulator
RGD ID: 1305422
Description: Predicted to be involved in negative regulation of autophagosome maturation; negative regulation of endocytosis; and negative regulation of phosphatidylinositol 3-kinase activity. Predicted to be located in cytosol; endosome; and nucleoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 15. Orthologous to human RUBCN (rubicon autophagy regulator); PARTICIPATES IN autophagy pathway; INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; bisphenol A; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC303885; RGD1305422; RUN and cysteine rich domain containing beclin 1 interacting protein; RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein; similar to mKIAA0226 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21167,907,534 - 67,964,347 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1167,907,516 - 67,964,314 (+)Ensembl
Rnor_6.01171,150,506 - 71,199,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,228,171 - 74,284,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,735,303 - 69,784,725 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,791,474 - 69,840,095 (+)NCBI
Celera1167,351,336 - 67,408,299 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Mammalian autophagy: core molecular machinery and signaling regulation. Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.
Additional References at PubMed
PMID:19270696   PMID:21062745   PMID:34996972  


Genomics

Comparative Map Data
Rubcn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21167,907,534 - 67,964,347 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1167,907,516 - 67,964,314 (+)Ensembl
Rnor_6.01171,150,506 - 71,199,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,228,171 - 74,284,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,735,303 - 69,784,725 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,791,474 - 69,840,095 (+)NCBI
Celera1167,351,336 - 67,408,299 (+)NCBICelera
Cytogenetic Map11q22NCBI
RUBCN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383197,668,867 - 197,749,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3197,668,867 - 197,749,727 (-)EnsemblGRCh38hg38GRCh38
GRCh373197,395,738 - 197,476,691 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363198,882,656 - 198,948,170 (-)NCBINCBI36hg18NCBI36
Celera3196,014,953 - 196,093,675 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3194,700,863 - 194,779,394 (-)NCBIHuRef
CHM1_13197,369,082 - 197,447,450 (-)NCBICHM1_1
T2T-CHM13v2.03200,401,254 - 200,482,196 (-)NCBI
Rubcn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,642,072 - 32,698,121 (-)NCBIGRCm39mm39
GRCm39 Ensembl1632,642,073 - 32,698,136 (-)Ensembl
GRCm381632,821,702 - 32,877,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,821,703 - 32,877,766 (-)EnsemblGRCm38mm10GRCm38
MGSCv371632,790,776 - 32,868,452 (-)NCBIGRCm37mm9NCBIm37
MGSCv361632,821,822 - 32,868,425 (-)NCBImm8
Celera1633,300,516 - 33,347,564 (-)NCBICelera
Cytogenetic Map16B3NCBI
Rubcn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,123,450 - 12,187,154 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,124,193 - 12,187,154 (+)NCBIChiLan1.0ChiLan1.0
RUBCN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13204,974,746 - 205,049,871 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3204,973,968 - 205,034,011 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03195,088,936 - 195,166,771 (-)NCBIMhudiblu_PPA_v0panPan3
RUBCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13328,947,439 - 29,011,737 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3328,946,944 - 29,009,346 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3328,968,568 - 29,032,995 (+)NCBI
ROS_Cfam_1.03329,178,166 - 29,242,864 (+)NCBI
ROS_Cfam_1.0 Ensembl3329,178,166 - 29,243,273 (+)Ensembl
UMICH_Zoey_3.13328,974,845 - 29,039,065 (+)NCBI
UNSW_CanFamBas_1.03329,021,133 - 29,085,572 (+)NCBI
UU_Cfam_GSD_1.03329,641,226 - 29,705,388 (+)NCBI
Rubcn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602125,447,313 - 125,515,113 (-)NCBI
SpeTri2.0NW_004936784370,173 - 438,263 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUBCN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13134,254,969 - 134,363,265 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113134,299,971 - 134,363,620 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213143,893,948 - 143,947,349 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RUBCN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11591,401,565 - 91,468,837 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1591,400,031 - 91,457,933 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604165,343,040 - 65,400,021 (-)NCBIVero_WHO_p1.0
Rubcn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,040,857 - 61,112,926 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473061,040,848 - 61,111,998 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,963,974 - 67,964,162 (+)MAPPERmRatBN7.2
Rnor_6.01171,198,882 - 71,199,069NCBIRnor6.0
Rnor_5.01174,283,955 - 74,284,142UniSTSRnor5.0
RGSC_v3.41169,784,353 - 69,784,540UniSTSRGSC3.4
Celera1167,407,927 - 67,408,114UniSTS
RH 3.4 Map11380.8UniSTS
Cytogenetic Map11q22UniSTS
RH128519  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21167,928,333 - 67,928,518 (+)MAPPERmRatBN7.2
Rnor_6.01171,163,352 - 71,163,536NCBIRnor6.0
Rnor_5.01174,248,283 - 74,248,467UniSTSRnor5.0
RGSC_v3.41169,748,437 - 69,748,621UniSTSRGSC3.4
Celera1167,372,026 - 67,372,210UniSTS
RH 3.4 Map11390.4UniSTS
Cytogenetic Map11q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 14 4 13 4 1 1 74 35 41 11 1
Low 6 43 37 6 37 7 10 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000082435   ⟹   ENSRNOP00000075115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,907,516 - 67,964,314 (+)Ensembl
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082594   ⟹   ENSRNOP00000073717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,915,224 - 67,964,314 (+)Ensembl
Rnor_6.0 Ensembl1171,151,132 - 71,197,035 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107263   ⟹   ENSRNOP00000097960
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,915,224 - 67,964,314 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109522   ⟹   ENSRNOP00000080345
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,907,516 - 67,964,314 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112016   ⟹   ENSRNOP00000088608
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1167,907,516 - 67,964,314 (+)Ensembl
RefSeq Acc Id: XM_039088921   ⟹   XP_038944849
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,915,184 - 67,964,347 (+)NCBI
RefSeq Acc Id: XM_039088922   ⟹   XP_038944850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,915,185 - 67,964,347 (+)NCBI
RefSeq Acc Id: XM_039088923   ⟹   XP_038944851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,907,534 - 67,964,346 (+)NCBI
RefSeq Acc Id: XM_039088924   ⟹   XP_038944852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,938,336 - 67,964,347 (+)NCBI
RefSeq Acc Id: XM_039088925   ⟹   XP_038944853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21167,915,184 - 67,964,347 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000075115   ⟸   ENSRNOT00000082435
RefSeq Acc Id: ENSRNOP00000073717   ⟸   ENSRNOT00000082594
RefSeq Acc Id: XP_038944851   ⟸   XM_039088923
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944853   ⟸   XM_039088925
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038944849   ⟸   XM_039088921
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944850   ⟸   XM_039088922
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944852   ⟸   XM_039088924
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000097960   ⟸   ENSRNOT00000107263
RefSeq Acc Id: ENSRNOP00000080345   ⟸   ENSRNOT00000109522
RefSeq Acc Id: ENSRNOP00000088608   ⟸   ENSRNOT00000112016

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K687-F1-model_v2 AlphaFold A0A0G2K687 1-962 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305422 AgrOrtholog
BioCyc Gene G2FUF-21117 BioCyc
Ensembl Genes ENSRNOG00000059880 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073717 ENTREZGENE
  ENSRNOP00000073717.2 UniProtKB/TrEMBL
  ENSRNOP00000075115.2 UniProtKB/TrEMBL
  ENSRNOP00000080345 ENTREZGENE
  ENSRNOP00000080345.1 UniProtKB/TrEMBL
  ENSRNOP00000088608.1 UniProtKB/TrEMBL
  ENSRNOP00000097960 ENTREZGENE
  ENSRNOP00000097960.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082435.2 UniProtKB/TrEMBL
  ENSRNOT00000082594 ENTREZGENE
  ENSRNOT00000082594.2 UniProtKB/TrEMBL
  ENSRNOT00000107263 ENTREZGENE
  ENSRNOT00000107263.1 UniProtKB/TrEMBL
  ENSRNOT00000109522 ENTREZGENE
  ENSRNOT00000109522.1 UniProtKB/TrEMBL
  ENSRNOT00000112016.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/TrEMBL
InterPro Run_dom UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/TrEMBL
  Zf-RING_9 UniProtKB/TrEMBL
NCBI Gene 303885 ENTREZGENE
Pfam RUN UniProtKB/TrEMBL
  zf-RING_9 UniProtKB/TrEMBL
PhenoGen Rubcn PhenoGen
PROSITE RUN UniProtKB/TrEMBL
SMART DUF4206 UniProtKB/TrEMBL
  RUN UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/TrEMBL
UniProt A0A0G2K687_RAT UniProtKB/TrEMBL
  A0A0G2K9T0_RAT UniProtKB/TrEMBL
  A0A8I5ZQF9_RAT UniProtKB/TrEMBL
  A0A8I6AJ73_RAT UniProtKB/TrEMBL
  A0A8I6GMR7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-10 Rubcn  rubicon autophagy regulator  Rubcn  RUN and cysteine rich domain containing beclin 1 interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Rubcn  RUN and cysteine rich domain containing beclin 1 interacting protein  Rubcn  RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-10-26 Rubcn  RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein  RGD1305422  similar to mKIAA0226 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1305422  similar to mKIAA0226 protein   RGD1305422_predicted  similar to mKIAA0226 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1305422_predicted  similar to mKIAA0226 protein (predicted)  LOC303885_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303885_predicted  similar to mKIAA0226 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL