Slc15a2 (solute carrier family 15 member 2) - Rat Genome Database

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Gene: Slc15a2 (solute carrier family 15 member 2) Rattus norvegicus
Analyze
Symbol: Slc15a2
Name: solute carrier family 15 member 2
RGD ID: 61972
Description: Enables dipeptide transmembrane transporter activity; peptide:proton symporter activity; and tripeptide transmembrane transporter activity. Involved in dipeptide import across plasma membrane; metanephric proximal tubule development; and tripeptide import across plasma membrane. Located in apical plasma membrane. Orthologous to human SLC15A2 (solute carrier family 15 member 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kidney H(+)/peptide cotransporter; MGC91625; oligopeptide transporter, kidney isoform; peptide transporter 2; solute carrier family 15 (H+/peptide transporter) member 2; solute carrier family 15 (H+/peptide transporter), member 2; solute carrier family 15 (oligopeptide transporter), member 2; solute carrier family 15, member 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,519,565 - 77,548,609 (+)NCBIGRCr8
mRatBN7.21164,014,182 - 64,043,228 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,014,182 - 64,043,225 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,826,580 - 72,855,620 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01165,488,810 - 65,517,850 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,519,800 - 64,548,903 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,932,664 - 66,961,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,932,614 - 66,961,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,022,984 - 70,052,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,819,551 - 65,849,924 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,877,139 - 65,907,513 (+)NCBI
Celera1163,484,245 - 63,513,303 (+)NCBICelera
Cytogenetic Map11q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsenous acid  (ISO)
benazepril  (EXP,ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
carnosine  (ISO)
chlordecone  (ISO)
cilazapril monohydrate  (EXP)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
D-gluconic acid  (EXP)
deoxycholic acid  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
diuron  (EXP)
enalapril  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fosinopril  (EXP)
furan  (EXP)
genistein  (EXP,ISO)
glycylsarcosine  (EXP,ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
Moexipril  (EXP)
N,N-diethyl-m-toluamide  (EXP)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paraquat  (EXP)
pentane-2,3-dione  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perindopril  (EXP)
permethrin  (EXP)
progesterone  (ISO)
quinapril hydrochloride  (EXP,ISO)
quinaprilat  (EXP,ISO)
ramipril  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
spirapril  (EXP,ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
trandolapril  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
warfarin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport. Beale JH, etal., Structure. 2015 Oct 6;23(10):1889-99. doi: 10.1016/j.str.2015.07.016. Epub 2015 Aug 27.
2. Stoichiometry and kinetics of the high-affinity H+-coupled peptide transporter PepT2. Chen XZ, etal., J Biol Chem. 1999 Jan 29;274(5):2773-9. doi: 10.1074/jbc.274.5.2773.
3. beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. Ganapathy ME, etal., J Biol Chem. 2000 Jan 21;275(3):1699-707.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Renogenic characterization and in vitro differentiation of rat amniotic fluid stem cells into renal proximal tubular- and juxtaglomerular-like cells. Minocha E, etal., In Vitro Cell Dev Biol Anim. 2019 Feb;55(2):138-147. doi: 10.1007/s11626-018-00315-2. Epub 2019 Jan 15.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals. Parker JL, etal., Sci Adv. 2021 Aug 25;7(35):eabh3355. doi: 10.1126/sciadv.abh3355. Print 2021 Aug.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Molecular cloning and tissue distribution of rat peptide transporter PEPT2. Saito H, etal., Biochim Biophys Acta 1996 Apr 26;1280(2):173-7.
14. Role of PEPT2 in peptide/mimetic trafficking at the blood-cerebrospinal fluid barrier: studies in rat choroid plexus epithelial cells in primary culture. Shu C, etal., J Pharmacol Exp Ther 2002 Jun;301(3):820-9.
15. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
16. Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice. Teuscher NS, etal., J Neurochem. 2004 Apr;89(2):375-82. doi: 10.1111/j.1471-4159.2004.02333.x.
Additional References at PubMed
PMID:7756356   PMID:11027540   PMID:12477932   PMID:14559717   PMID:14715149   PMID:15804184   PMID:16041713   PMID:16202478   PMID:17028260   PMID:17034769   PMID:17452417   PMID:18367661  
PMID:18713951   PMID:18762712   PMID:19052442   PMID:19056867   PMID:19199708   PMID:19913073   PMID:23988852   PMID:24113008   PMID:24548120   PMID:28831683   PMID:33404911  


Genomics

Comparative Map Data
Slc15a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,519,565 - 77,548,609 (+)NCBIGRCr8
mRatBN7.21164,014,182 - 64,043,228 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,014,182 - 64,043,225 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1172,826,580 - 72,855,620 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01165,488,810 - 65,517,850 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,519,800 - 64,548,903 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,932,664 - 66,961,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,932,614 - 66,961,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01170,022,984 - 70,052,075 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,819,551 - 65,849,924 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,877,139 - 65,907,513 (+)NCBI
Celera1163,484,245 - 63,513,303 (+)NCBICelera
Cytogenetic Map11q21NCBI
SLC15A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383121,894,401 - 121,944,188 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3121,894,401 - 121,944,188 (+)EnsemblGRCh38hg38GRCh38
GRCh373121,613,248 - 121,663,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,095,977 - 123,143,148 (+)NCBINCBI36Build 36hg18NCBI36
Build 343123,095,976 - 123,143,147NCBI
Celera3120,023,021 - 120,072,858 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3118,987,216 - 119,037,039 (+)NCBIHuRef
CHM1_13121,577,211 - 121,627,066 (+)NCBICHM1_1
T2T-CHM13v2.03124,614,370 - 124,664,153 (+)NCBIT2T-CHM13v2.0
Slc15a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391636,570,523 - 36,605,506 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1636,570,539 - 36,605,324 (-)EnsemblGRCm39 Ensembl
GRCm381636,750,161 - 36,785,158 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1636,750,177 - 36,784,962 (-)EnsemblGRCm38mm10GRCm38
MGSCv371636,750,250 - 36,785,048 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361636,669,420 - 36,704,201 (-)NCBIMGSCv36mm8
Celera1637,165,904 - 37,195,398 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.97NCBI
Slc15a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542721,221,750 - 21,255,725 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542721,221,778 - 21,255,725 (+)NCBIChiLan1.0ChiLan1.0
SLC15A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22119,848,009 - 119,901,353 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13119,852,773 - 119,906,132 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03118,996,023 - 119,044,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13125,902,978 - 125,951,963 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3125,902,978 - 125,951,963 (+)Ensemblpanpan1.1panPan2
SLC15A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13325,154,415 - 25,190,715 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3325,154,448 - 25,189,929 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3325,179,881 - 25,216,242 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03325,389,745 - 25,426,316 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3325,389,827 - 25,426,392 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13325,188,148 - 25,224,653 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03325,230,387 - 25,266,965 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03325,788,327 - 25,824,919 (+)NCBIUU_Cfam_GSD_1.0
Slc15a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602129,205,990 - 129,241,546 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365368,280,448 - 8,316,064 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365368,280,537 - 8,316,011 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC15A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13138,595,958 - 138,632,675 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113138,595,942 - 138,634,473 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213148,224,099 - 148,259,030 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC15A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12258,916,389 - 58,966,725 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2258,913,676 - 58,966,906 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041107,356,438 - 107,408,360 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc15a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624912179,969 - 222,909 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624912180,048 - 222,909 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc15a2
169 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:526
Count of miRNA genes:242
Interacting mature miRNAs:289
Transcripts:ENSRNOT00000003189
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat

Markers in Region
RH127511  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21164,042,925 - 64,043,122 (+)MAPPERmRatBN7.2
Rnor_6.01166,961,406 - 66,961,602NCBIRnor6.0
Rnor_5.01170,051,773 - 70,051,969UniSTSRnor5.0
RGSC_v3.41165,849,629 - 65,849,825UniSTSRGSC3.4
Celera1163,513,001 - 63,513,197UniSTS
RH 3.4 Map11486.8UniSTS
Cytogenetic Map11q22UniSTS
BF405220  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21164,040,540 - 64,040,688 (+)MAPPERmRatBN7.2
Rnor_6.01166,959,021 - 66,959,168NCBIRnor6.0
Rnor_5.01170,049,388 - 70,049,535UniSTSRnor5.0
RGSC_v3.41165,847,244 - 65,847,391UniSTSRGSC3.4
Celera1163,510,616 - 63,510,763UniSTS
RH 3.4 Map11467.3UniSTS
Cytogenetic Map11q22UniSTS
RH139643  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21164,042,524 - 64,042,717 (+)MAPPERmRatBN7.2
Rnor_6.01166,961,005 - 66,961,197NCBIRnor6.0
Rnor_5.01170,051,372 - 70,051,564UniSTSRnor5.0
RGSC_v3.41165,849,228 - 65,849,420UniSTSRGSC3.4
Celera1163,512,600 - 63,512,792UniSTS
RH 3.4 Map11470.4UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 47 113 87 86 55 25 55 6 212 95 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000003189   ⟹   ENSRNOP00000003189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1164,014,182 - 64,043,225 (+)Ensembl
Rnor_6.0 Ensembl1166,932,614 - 66,961,713 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106100   ⟹   ENSRNOP00000094276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1164,014,182 - 64,026,088 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111085   ⟹   ENSRNOP00000086877
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1164,014,182 - 64,043,225 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120269   ⟹   ENSRNOP00000078734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1164,014,182 - 64,043,225 (+)Ensembl
RefSeq Acc Id: NM_031672   ⟹   NP_113860
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,519,565 - 77,548,609 (+)NCBI
mRatBN7.21164,014,182 - 64,043,228 (+)NCBI
Rnor_6.01166,932,664 - 66,961,708 (+)NCBI
Rnor_5.01170,022,984 - 70,052,075 (+)NCBI
RGSC_v3.41165,819,551 - 65,849,924 (+)RGD
Celera1163,484,245 - 63,513,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063270759   ⟹   XP_063126829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,522,622 - 77,548,609 (+)NCBI
RefSeq Acc Id: NP_113860   ⟸   NM_031672
- UniProtKB: A0A0H2UHA7 (UniProtKB/TrEMBL),   A6IRB4 (UniProtKB/TrEMBL),   A0A8I6A6Q4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003189   ⟸   ENSRNOT00000003189
Ensembl Acc Id: ENSRNOP00000078734   ⟸   ENSRNOT00000120269
Ensembl Acc Id: ENSRNOP00000094276   ⟸   ENSRNOT00000106100
Ensembl Acc Id: ENSRNOP00000086877   ⟸   ENSRNOT00000111085
RefSeq Acc Id: XP_063126829   ⟸   XM_063270759
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63424-F1-model_v2 AlphaFold Q63424 1-729 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61972 AgrOrtholog
BioCyc Gene G2FUF-21240 BioCyc
Ensembl Genes ENSRNOG00000002305 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003189.6 UniProtKB/TrEMBL
  ENSRNOT00000106100.1 UniProtKB/TrEMBL
  ENSRNOT00000111085.1 UniProtKB/TrEMBL
  ENSRNOT00000120269.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7098404 IMAGE-MGC_LOAD
InterPro Alpha/beta_knot_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Oligopep_transport UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  POT_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTR2_symporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60577 UniProtKB/TrEMBL
MGC_CLONE MGC:91625 IMAGE-MGC_LOAD
NCBI Gene 60577 ENTREZGENE
PANTHER PTHR11654 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 15 MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PTR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc15a2 PhenoGen
PROSITE PTR2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTR2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002305 RatGTEx
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF75217 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC206838
UniProt A0A0H2UHA7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZLE5_RAT UniProtKB/TrEMBL
  A0A8I6A6Q4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AL86_RAT UniProtKB/TrEMBL
  A6IRB4 ENTREZGENE, UniProtKB/TrEMBL
  A6IRB5_RAT UniProtKB/TrEMBL
  A6IRB6_RAT UniProtKB/TrEMBL
  A6IRB7_RAT UniProtKB/TrEMBL
  A6IRB8_RAT UniProtKB/TrEMBL
  Q5U401_RAT UniProtKB/TrEMBL
  Q63424 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Slc15a2  solute carrier family 15 member 2  Slc15a2  solute carrier family 15 (oligopeptide transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-02 Slc15a2  solute carrier family 15 (oligopeptide transporter), member 2  Slc15a2  solute carrier family 15 (H+/peptide transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc15a2  solute carrier family 15 (H+/peptide transporter), member 2    solute carrier family 15, member 2  Name updated 1299863 APPROVED
2002-06-10 Slc15a2  solute carrier family 15, member 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the apical and subapical regions of choroid plexus epithelial cells 729764