Tnk2 (tyrosine kinase, non-receptor, 2) - Rat Genome Database

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Gene: Tnk2 (tyrosine kinase, non-receptor, 2) Rattus norvegicus
Analyze
Symbol: Tnk2
Name: tyrosine kinase, non-receptor, 2
RGD ID: 1305957
Description: Enables protein tyrosine kinase activity. Predicted to be involved in several processes, including positive regulation of peptidyl-tyrosine phosphorylation; regulation of clathrin-dependent endocytosis; and spermatid development. Predicted to be located in several cellular components, including clathrin-coated pit; cytoophidium; and cytoplasmic vesicle. Predicted to be part of Grb2-EGFR complex. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human TNK2 (tyrosine kinase non receptor 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ACK-1; activated CDC42 kinase 1; activated p21cdc42Hs kinase; LOC303882; MGC94214; tyrosine kinase non-receptor protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,114,725 - 68,154,254 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1168,114,726 - 68,154,009 (-)Ensembl
Rnor_6.01171,348,726 - 71,388,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,348,717 - 71,387,992 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,431,230 - 74,470,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,927,509 - 69,966,854 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,985,098 - 70,024,443 (-)NCBI
Celera1167,547,447 - 67,587,473 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:10587647   PMID:10618719   PMID:12477932   PMID:16472662   PMID:17182860   PMID:18262180   PMID:18993068   PMID:19946888   PMID:20086093   PMID:20333297   PMID:20979614   PMID:21169560  
PMID:23562806   PMID:23686771   PMID:25223282   PMID:25416956  


Genomics

Comparative Map Data
Tnk2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,114,725 - 68,154,254 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1168,114,726 - 68,154,009 (-)Ensembl
Rnor_6.01171,348,726 - 71,388,520 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,348,717 - 71,387,992 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,431,230 - 74,470,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,927,509 - 69,966,854 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,985,098 - 70,024,443 (-)NCBI
Celera1167,547,447 - 67,587,473 (-)NCBICelera
Cytogenetic Map11q22NCBI
TNK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383195,863,364 - 195,908,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3195,863,364 - 195,911,945 (-)EnsemblGRCh38hg38GRCh38
GRCh373195,590,235 - 195,635,422 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,074,633 - 197,120,277 (-)NCBINCBI36hg18NCBI36
Build 343197,078,545 - 197,124,190NCBI
Celera3194,132,138 - 194,176,550 (-)NCBI
Cytogenetic Map3q29NCBI
HuRef3192,870,965 - 192,916,101 (-)NCBIHuRef
CHM1_13195,555,272 - 195,606,419 (-)NCBICHM1_1
T2T-CHM13v2.03198,449,491 - 198,494,501 (+)NCBI
Tnk2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,462,699 - 32,502,311 (+)NCBIGRCm39mm39
GRCm39 Ensembl1632,462,692 - 32,502,311 (+)Ensembl
GRCm381632,644,099 - 32,683,493 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,643,874 - 32,683,493 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,644,729 - 32,683,579 (+)NCBIGRCm37mm9NCBIm37
MGSCv361632,564,608 - 32,603,240 (+)NCBImm8
Celera1633,124,376 - 33,163,447 (+)NCBICelera
Cytogenetic Map16B3NCBI
Tnk2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,300,572 - 12,338,058 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,302,463 - 12,337,976 (-)NCBIChiLan1.0ChiLan1.0
TNK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13203,219,978 - 203,254,498 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v03193,254,017 - 193,302,863 (-)NCBIMhudiblu_PPA_v0panPan3
TNK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,153,636 - 29,177,568 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,152,851 - 29,179,718 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3329,178,360 - 29,220,811 (-)NCBI
ROS_Cfam_1.03329,386,486 - 29,428,984 (-)NCBI
ROS_Cfam_1.0 Ensembl3329,386,488 - 29,412,066 (-)Ensembl
UMICH_Zoey_3.13329,171,866 - 29,196,006 (-)NCBI
UNSW_CanFamBas_1.03329,227,984 - 29,270,384 (-)NCBI
UU_Cfam_GSD_1.03329,848,891 - 29,891,309 (-)NCBI
Tnk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602125,200,392 - 125,249,164 (+)NCBI
SpeTri2.0NW_004936784636,105 - 685,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13134,081,697 - 134,124,826 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113134,082,266 - 134,124,826 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213143,624,416 - 143,666,696 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11591,187,702 - 91,232,391 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1591,201,008 - 91,232,399 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604165,037,963 - 65,084,349 (+)NCBIVero_WHO_p1.0
Tnk2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,236,983 - 61,273,166 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473061,237,653 - 61,272,499 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AF037260  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,114,939 - 68,115,055 (+)MAPPERmRatBN7.2
Rnor_6.01171,348,941 - 71,349,056NCBIRnor6.0
Rnor_5.01174,431,445 - 74,431,560UniSTSRnor5.0
RGSC_v3.41169,927,724 - 69,927,839UniSTSRGSC3.4
Celera1167,547,662 - 67,547,777UniSTS
Cytogenetic Map11q22UniSTS
RH134491  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,114,811 - 68,115,000 (+)MAPPERmRatBN7.2
Rnor_6.01171,348,813 - 71,349,001NCBIRnor6.0
Rnor_5.01174,431,317 - 74,431,505UniSTSRnor5.0
RGSC_v3.41169,927,596 - 69,927,784UniSTSRGSC3.4
Celera1167,547,534 - 67,547,722UniSTS
RH 3.4 Map11393.0UniSTS
Cytogenetic Map11q22UniSTS
RH143928  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,115,257 - 68,115,412 (+)MAPPERmRatBN7.2
Rnor_6.01171,349,259 - 71,349,413NCBIRnor6.0
Rnor_5.01174,431,763 - 74,431,917UniSTSRnor5.0
RGSC_v3.41169,928,042 - 69,928,196UniSTSRGSC3.4
Celera1167,547,980 - 67,548,134UniSTS
RH 3.4 Map11403.5UniSTS
Cytogenetic Map11q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
4889859Pur28Proteinuria QTL 2819.50.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:111
Count of miRNA genes:74
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000002411
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 30 22 13 22 3 74 27 34 3
Low 11 27 19 6 19 8 8 8 7 8 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC136847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002411   ⟹   ENSRNOP00000002411
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,114,726 - 68,154,009 (-)Ensembl
Rnor_6.0 Ensembl1171,348,727 - 71,387,992 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084768   ⟹   ENSRNOP00000070836
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,114,726 - 68,139,370 (-)Ensembl
Rnor_6.0 Ensembl1171,348,717 - 71,368,456 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085568   ⟹   ENSRNOP00000072336
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,114,726 - 68,136,982 (-)Ensembl
Rnor_6.0 Ensembl1171,350,817 - 71,368,440 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111788   ⟹   ENSRNOP00000084054
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,114,726 - 68,154,009 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116648   ⟹   ENSRNOP00000085601
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,114,726 - 68,154,009 (-)Ensembl
RefSeq Acc Id: NM_001008336   ⟹   NP_001008337
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,154,009 (-)NCBI
Rnor_6.01171,348,726 - 71,387,992 (-)NCBI
Rnor_5.01174,431,230 - 74,470,437 (-)NCBI
RGSC_v3.41169,927,509 - 69,966,854 (-)RGD
Celera1167,547,447 - 67,587,473 (-)RGD
Sequence:
RefSeq Acc Id: XM_017597980   ⟹   XP_017453469
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,206 (-)NCBI
Rnor_6.01171,348,726 - 71,371,213 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597981   ⟹   XP_017453470
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,137,207 (-)NCBI
Rnor_6.01171,350,857 - 71,371,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597983   ⟹   XP_017453472
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,139,599 (-)NCBI
Rnor_6.01171,348,726 - 71,374,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597984   ⟹   XP_017453473
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,206 (-)NCBI
Rnor_6.01171,348,726 - 71,371,213 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597985   ⟹   XP_017453474
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,137,207 (-)NCBI
Rnor_6.01171,350,857 - 71,371,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597987   ⟹   XP_017453476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,137,207 (-)NCBI
Rnor_6.01171,350,857 - 71,371,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597990   ⟹   XP_017453479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,137,207 (-)NCBI
Rnor_6.01171,350,857 - 71,371,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088304   ⟹   XP_038944232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088305   ⟹   XP_038944233
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088306   ⟹   XP_038944234
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,139,599 (-)NCBI
RefSeq Acc Id: XM_039088307   ⟹   XP_038944235
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088309   ⟹   XP_038944237
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088310   ⟹   XP_038944238
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,154,254 (-)NCBI
RefSeq Acc Id: XM_039088311   ⟹   XP_038944239
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088312   ⟹   XP_038944240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,139,598 (-)NCBI
RefSeq Acc Id: XM_039088314   ⟹   XP_038944242
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088315   ⟹   XP_038944243
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,137,207 (-)NCBI
RefSeq Acc Id: XM_039088316   ⟹   XP_038944244
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,139,602 (-)NCBI
RefSeq Acc Id: XM_039088317   ⟹   XP_038944245
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,116,856 - 68,139,601 (-)NCBI
RefSeq Acc Id: XM_039088318   ⟹   XP_038944246
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,153,924 (-)NCBI
RefSeq Acc Id: XM_039088319   ⟹   XP_038944247
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,153,924 (-)NCBI
RefSeq Acc Id: XM_039088320   ⟹   XP_038944248
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,122,398 (-)NCBI
RefSeq Acc Id: XM_039088321   ⟹   XP_038944249
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,126,414 (-)NCBI
RefSeq Acc Id: XM_039088322   ⟹   XP_038944250
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,119,402 - 68,137,206 (-)NCBI
RefSeq Acc Id: XM_039088323   ⟹   XP_038944251
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21168,114,725 - 68,122,398 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001008337 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453469 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453470 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453472 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453473 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453474 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453476 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453479 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944232 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944233 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944234 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944235 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944237 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944238 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944239 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944240 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944242 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944243 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944244 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944245 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944246 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944247 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944248 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944249 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944251 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85825 (Get FASTA)   NCBI Sequence Viewer  
  EDM11400 (Get FASTA)   NCBI Sequence Viewer  
  EDM11401 (Get FASTA)   NCBI Sequence Viewer  
  EDM11402 (Get FASTA)   NCBI Sequence Viewer  
  EDM11403 (Get FASTA)   NCBI Sequence Viewer  
  EDM11404 (Get FASTA)   NCBI Sequence Viewer  
  Q5U2X5 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001008337   ⟸   NM_001008336
- UniProtKB: Q5U2X5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017453472   ⟸   XM_017597983
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017453473   ⟸   XM_017597984
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_017453469   ⟸   XM_017597980
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017453479   ⟸   XM_017597990
- Peptide Label: isoform X18
- Sequence:
RefSeq Acc Id: XP_017453476   ⟸   XM_017597987
- Peptide Label: isoform X13
- Sequence:
RefSeq Acc Id: XP_017453474   ⟸   XM_017597985
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_017453470   ⟸   XM_017597981
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSRNOP00000070836   ⟸   ENSRNOT00000084768
RefSeq Acc Id: ENSRNOP00000072336   ⟸   ENSRNOT00000085568
RefSeq Acc Id: ENSRNOP00000002411   ⟸   ENSRNOT00000002411
RefSeq Acc Id: XP_038944238   ⟸   XM_039088310
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038944247   ⟸   XM_039088319
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038944246   ⟸   XM_039088318
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038944234   ⟸   XM_039088306
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944235   ⟸   XM_039088307
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038944237   ⟸   XM_039088309
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038944243   ⟸   XM_039088315
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038944239   ⟸   XM_039088311
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038944233   ⟸   XM_039088305
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944232   ⟸   XM_039088304
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944249   ⟸   XM_039088321
- Peptide Label: isoform X23
RefSeq Acc Id: XP_038944251   ⟸   XM_039088323
- Peptide Label: isoform X25
RefSeq Acc Id: XP_038944248   ⟸   XM_039088320
- Peptide Label: isoform X22
RefSeq Acc Id: XP_038944244   ⟸   XM_039088316
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038944245   ⟸   XM_039088317
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038944240   ⟸   XM_039088312
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038944242   ⟸   XM_039088314
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038944250   ⟸   XM_039088322
- Peptide Label: isoform X24
RefSeq Acc Id: ENSRNOP00000085601   ⟸   ENSRNOT00000116648
RefSeq Acc Id: ENSRNOP00000084054   ⟸   ENSRNOT00000111788
Protein Domains
Protein kinase   SH3   UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2X5-F1-model_v2 AlphaFold Q5U2X5 1-1040 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 71352474 71352475 G A snv WKY/Gcrc (RGD), SHRSP/A3NCrl (2019), BBDP/Wor (RGD), MNS/Gib (RGD), SHR/NHsd (RGD), SHR/OlalpcvMcwi (2019), BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), HXB10/IpcvMcwi (2019)
11 71361858 71361859 C T snv WAG/RijCrl (2020), WAG/Rij (RGD)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
11 68118473 68118474 G A snv BXH2/CubMcwi (2020), BXH3/CubMcwi (2020), HXB10/IpcvMcwi (2019), SHRSP/A3NCrl (2019), SHR/OlalpcvMcwi (2019)
11 68127868 68127869 C T snv WAG/RijCrl (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305957 AgrOrtholog
BioCyc Gene G2FUF-21110 BioCyc
Ensembl Genes ENSRNOG00000001769 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002411 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000070836 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072336 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000085601 ENTREZGENE
Ensembl Transcript ENSRNOT00000002411 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000084768 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000085568 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000116648 ENTREZGENE
Gene3D-CATH 4.10.680.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7130376 IMAGE-MGC_LOAD
InterPro Ack1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc42-bd-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cdc42_binding_dom-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mig-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:303882 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94214 IMAGE-MGC_LOAD
NCBI Gene 303882 ENTREZGENE
PANTHER PTHR14254:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GTPase_binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Inhibitor_Mig-6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnk2 PhenoGen
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYY3_RAT UniProtKB/TrEMBL
  ACK1_RAT UniProtKB/Swiss-Prot
  F1M7W9_RAT UniProtKB/TrEMBL
  Q5U2X5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Tnk2  tyrosine kinase, non-receptor, 2  LOC682784  similar to tyrosine kinase, non-receptor, 2  Data Merged 1643240 APPROVED
2006-11-20 LOC682784  similar to tyrosine kinase, non-receptor, 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Tnk2  tyrosine kinase, non-receptor, 2  Tnk2_predicted  tyrosine kinase, non-receptor, 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tnk2_predicted  tyrosine kinase, non-receptor, 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED