Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Muc4 (mucin 4, cell surface associated) Rattus norvegicus
Symbol: Muc4
Name: mucin 4, cell surface associated
Description: Exhibits ErbB-2 class receptor binding activity. Involved in several processes, including estrous cycle; negative regulation of T cell mediated cytotoxicity directed against tumor cell target; and negative regulation of cell adhesion. Localizes to several cellular components, including apical plasma membrane; extracellular space; and microvillus membrane. Colocalizes with endoplasmic reticulum. Biomarker of cholangiocarcinoma; corneal neovascularization; mucositis; and otitis media. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human MUC4 (mucin 4, cell surface associated); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: MODEL
Also known as: ascites sialoglycoprotein; ASGP; ASGP-1; MUC-4; mucin 4; mucin-4; pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin
Homo sapiens (human) : MUC4 (mucin 4, cell surface associated)  HGNC  Alliance
Mus musculus (house mouse) : Muc4 (mucin 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc4 (mucin 4, cell surface associated)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC4 (mucin 4, cell surface associated)
Canis lupus familiaris (dog) : MUC4 (mucin 4, cell surface associated)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc4 (mucin 4, cell surface associated)
Sus scrofa (pig) : MUC4 (mucin 4, cell surface associated)
Chlorocebus sabaeus (African green monkey) : MUC4 (mucin 4, cell surface associated)
Heterocephalus glaber (naked mole-rat) : Muc4 (mucin 4, cell surface associated)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01171,242,973 - 71,285,217 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,243,334 - 71,284,939 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,327,777 - 74,369,829 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,830,276 - 69,858,366 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11169,887,864 - 69,915,763 (-)NCBI
Celera1167,453,205 - 67,496,554 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Muc4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621331
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.