Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Urb1 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of URB1 mRNA] | CTD | PMID:31150632 | Urb1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Urb1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of URB1 mRNA | CTD | PMID:28960355 | Urb1 | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | URB1 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to URB1 protein | CTD | PMID:32991956 | Urb1 | Rat | 17beta-estradiol | increases expression | ISO | URB1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of URB1 mRNA | CTD | PMID:23019147 and PMID:31614463 | Urb1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Urb1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Urb1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of URB1 mRNA more ... | CTD | PMID:28628672 | Urb1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of URB1 mRNA | CTD | PMID:28628672 | Urb1 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | URB1 (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of URB1 gene | CTD | PMID:31601247 | Urb1 | Rat | aflatoxin B1 | increases methylation | ISO | URB1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of URB1 gene | CTD | PMID:27153756 | Urb1 | Rat | aflatoxin B1 | decreases methylation | ISO | URB1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of URB1 exon | CTD | PMID:30157460 | Urb1 | Rat | all-trans-retinoic acid | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of URB1 mRNA | CTD | PMID:33167477 | Urb1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of URB1 mRNA | CTD | PMID:30779732 | Urb1 | Rat | aristolochic acid A | increases expression | ISO | URB1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of URB1 mRNA | CTD | PMID:33212167 | Urb1 | Rat | arsenite(3-) | decreases expression | ISO | Urb1 (Mus musculus) | 6480464 | arsenite results in decreased expression of URB1 protein | CTD | PMID:37955338 | Urb1 | Rat | benzo[a]pyrene | increases methylation | ISO | URB1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of URB1 3' UTR | CTD | PMID:27901495 | Urb1 | Rat | benzo[e]pyrene | decreases methylation | ISO | URB1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of URB1 exon | CTD | PMID:30157460 | Urb1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of URB1 mRNA | CTD | PMID:25181051 | Urb1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of URB1 mRNA | CTD | PMID:30816183 and PMID:32528016 | Urb1 | Rat | bisphenol A | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of URB1 mRNA | CTD | PMID:28628672 | Urb1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of URB1 gene | CTD | PMID:28505145 | Urb1 | Rat | bisphenol F | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of URB1 mRNA | CTD | PMID:28628672 | Urb1 | Rat | cisplatin | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of URB1 mRNA | CTD | PMID:27594783 | Urb1 | Rat | crocidolite asbestos | increases expression | ISO | Urb1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in increased expression of URB1 mRNA | CTD | PMID:19446018 | Urb1 | Rat | dexamethasone | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of URB1 mRNA more ... | CTD | PMID:28628672 | Urb1 | Rat | dicrotophos | increases expression | ISO | URB1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of URB1 mRNA | CTD | PMID:28302478 | Urb1 | Rat | doxorubicin | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of URB1 mRNA | CTD | PMID:29803840 | Urb1 | Rat | epoxiconazole | decreases expression | ISO | Urb1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of URB1 mRNA | CTD | PMID:35436446 | Urb1 | Rat | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of URB1 protein | CTD | PMID:24552547 | Urb1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of URB1 mRNA | CTD | PMID:33387578 | Urb1 | Rat | indometacin | multiple interactions | ISO | URB1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of URB1 mRNA more ... | CTD | PMID:28628672 | Urb1 | Rat | ivermectin | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of URB1 protein | CTD | PMID:32959892 | Urb1 | Rat | maneb | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of URB1 mRNA | CTD | PMID:36117858 | Urb1 | Rat | methapyrilene | decreases methylation | ISO | URB1 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of URB1 exon | CTD | PMID:30157460 | Urb1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of URB1 gene | CTD | PMID:35440735 | Urb1 | Rat | omega-6 fatty acid | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | Fatty Acids and Omega-6 results in decreased expression of URB1 mRNA | CTD | PMID:16823509 | Urb1 | Rat | paracetamol | affects expression | ISO | Urb1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of URB1 mRNA | CTD | PMID:17562736 | Urb1 | Rat | paraquat | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of URB1 mRNA | CTD | PMID:36117858 | Urb1 | Rat | PCB138 | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Urb1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Urb1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of URB1 mRNA | CTD | PMID:36331819 | Urb1 | Rat | potassium chromate | increases expression | ISO | URB1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of URB1 mRNA | CTD | PMID:22714537 | Urb1 | Rat | sodium arsenite | decreases expression | ISO | URB1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of URB1 mRNA | CTD | PMID:38568856 | Urb1 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of URB1 mRNA | CTD | PMID:25993096 | Urb1 | Rat | sunitinib | increases expression | ISO | URB1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of URB1 mRNA | CTD | PMID:31533062 | Urb1 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of URB1 mRNA] | CTD | PMID:31150632 | Urb1 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of URB1 mRNA | CTD | PMID:31150632 | Urb1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of URB1 mRNA | CTD | PMID:23411599 and PMID:34492290 | Urb1 | Rat | titanium dioxide | decreases methylation | ISO | Urb1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of URB1 promoter | CTD | PMID:35295148 | Urb1 | Rat | titanium dioxide | affects methylation | ISO | Urb1 (Mus musculus) | 6480464 | titanium dioxide affects the methylation of URB1 gene | CTD | PMID:35295148 | Urb1 | Rat | triphenyl phosphate | affects expression | ISO | URB1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of URB1 mRNA | CTD | PMID:37042841 | Urb1 | Rat | Triptolide | increases expression | ISO | Urb1 (Mus musculus) | 6480464 | triptolide results in increased expression of URB1 mRNA | CTD | PMID:32835833 | Urb1 | Rat | tungsten | decreases expression | ISO | Urb1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of URB1 mRNA | CTD | PMID:30912803 | |