Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cd80 (Cd80 molecule) Rattus norvegicus
Analyze
Symbol: Cd80
Name: Cd80 molecule
Description: Predicted to have coreceptor activity. Involved in positive regulation of T cell proliferation. Localizes to the cell surface. Used to study adult T-cell leukemia; anti-basement membrane glomerulonephritis; malignant glioma; and periodontal disease. Biomarker of kidney failure. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human CD80 (CD80 molecule); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: B7-1; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 antigen; CD80-like; LOC100360171; T-lymphocyte activation antigen CD80
Orthologs:
Homo sapiens (human) : CD80 (CD80 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd80 (CD80 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd80 (CD80 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD80 (CD80 molecule)
Canis lupus familiaris (dog) : CD80 (CD80 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd80 (CD80 molecule)
Sus scrofa (pig) : CD80 (CD80 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01164,815,201 - 64,855,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01167,255,123 - 67,291,544 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,045,358 - 64,070,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11164,102,946 - 64,127,661 (-)NCBI
Celera1161,768,874 - 61,793,351 (-)NCBICelera
Cytogenetic Map11q21NCBI
RH 3.4 Map11500.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd80
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2314
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.