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Gene: Cd80 (CD80 antigen) Mus musculus
Symbol: Cd80
Name: CD80 antigen
Description: Predicted to have coreceptor activity. Involved in T cell costimulation; cellular response to lipopolysaccharide; and positive regulation of alpha-beta T cell proliferation. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in heart ventricle and skin. Orthologous to human CD80 (CD80 molecule); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activation B7-1 antigen; B7 protein; B7-1; B7.1; B71; Cd28l; Ly-53; Ly53; MIC17; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
Homo sapiens (human) : CD80 (CD80 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd80 (Cd80 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd80 (CD80 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD80 (CD80 molecule)
Canis lupus familiaris (dog) : CD80 (CD80 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd80 (CD80 molecule)
Sus scrofa (pig) : CD80 (CD80 molecule)
Chlorocebus sabaeus (green monkey) : CD80 (CD80 molecule)
Heterocephalus glaber (naked mole-rat) : Cd80 (CD80 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1638,455,561 - 38,496,335 (+)Ensembl
GRCm381638,457,430 - 38,495,958 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371638,459,013 - 38,487,015 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,378,414 - 38,418,102 (+)NCBImm8
Celera1638,869,381 - 38,897,547 (+)NCBICelera
Cytogenetic Map16 B4NCBI
cM Map1626.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd80
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10316
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.