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Gene: Cd80 (CD80 antigen) Mus musculus
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Symbol: Cd80
Name: CD80 antigen
Description: Predicted to have coreceptor activity. Involved in T cell costimulation; cellular response to lipopolysaccharide; and positive regulation of alpha-beta T cell proliferation. Localizes to the external side of plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Is expressed in heart ventricle and skin. Orthologous to human CD80 (CD80 molecule); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activation B7-1 antigen; B7 protein; B7-1; B7.1; B71; Cd28l; Ly-53; Ly53; MIC17; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
Orthologs:
Homo sapiens (human) : CD80 (CD80 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd80 (Cd80 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd80 (CD80 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD80 (CD80 molecule)
Canis lupus familiaris (dog) : CD80 (CD80 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd80 (CD80 molecule)
Sus scrofa (pig) : CD80 (CD80 molecule)
Chlorocebus sabaeus (green monkey) : CD80 (CD80 molecule)
Heterocephalus glaber (naked mole-rat) : Cd80 (CD80 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1638,455,561 - 38,496,335 (+)Ensembl
GRCm381638,457,430 - 38,495,958 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371638,459,013 - 38,487,015 (+)NCBIGRCm37mm9NCBIm37
MGSCv361638,378,414 - 38,418,102 (+)NCBImm8
Celera1638,869,381 - 38,897,547 (+)NCBICelera
Cytogenetic Map16 B4NCBI
cM Map1626.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd80
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10316
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.