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Gene: Mylk (myosin light chain kinase) Rattus norvegicus
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Symbol: Mylk
Name: myosin light chain kinase
Description: Predicted to have enzyme binding activity and myosin light chain kinase activity. Predicted to be involved in several processes, including aorta smooth muscle tissue morphogenesis; bleb assembly; and cellular response to metal ion. Predicted to localize to several cellular components, including the cleavage furrow; lamellipodium; and stress fiber. Human ortholog(s) of this gene implicated in adult respiratory distress syndrome; asthma; and thoracic aortic aneurysm. Orthologous to human MYLK (myosin light chain kinase); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC288057; myosin light chain kinase, smooth muscle; myosin, light polypeptide kinase
Orthologs:
Homo sapiens (human) : MYLK (myosin light chain kinase)  HGNC  Alliance
Mus musculus (house mouse) : Mylk (myosin, light polypeptide kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mylk (myosin light chain kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MYLK (myosin light chain kinase)
Canis lupus familiaris (dog) : MYLK (myosin light chain kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mylk (myosin light chain kinase)
Sus scrofa (pig) : MYLK (myosin light chain kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01169,013,060 - 69,260,039 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,013,050 - 69,223,158 (-)Ensembl
Rnor_5.01172,103,710 - 72,350,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,602,540 - 67,848,794 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11167,661,997 - 67,920,369 (-)NCBI
Celera1165,239,196 - 65,448,599 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mylk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310915
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.