Cd200r1 (CD200 receptor 1) - Rat Genome Database

Name: Cd200r1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Cd200r1 (CD200 receptor 1) Rattus norvegicus

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Symbol:

Cd200r1

Name:

CD200 receptor 1

RGD ID:

61837

Description:

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including negative regulation of interleukin-6 production; negative regulation of mononuclear cell migration; and negative regulation of neuroinflammatory response. Located in cell surface. Orthologous to human CD200R1 (CD200 receptor 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

antigen identified by monoclonal antibody MRC OX-2 receptor; CD200 cell surface glycoprotein receptor; cell surface glycoprotein CD200 receptor 1; cell surface glycoprotein OX2 receptor 1; Mox2r; OX102 antigen; OX2 receptor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CD200R1 (CD200 receptor 1)	HGNC	EggNOG, Ensembl, HomoloGene, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cd200r1 (CD200 receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cd200r1 (CD200 receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC487977 (cell surface glycoprotein CD200 receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103228312 (cell surface glycoprotein CD200 receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CD200R1L (CD200 receptor 1 like)	HGNC	Ensembl, Inparanoid, OrthoDB, Panther, PhylomeDB, Treefam
Alliance orthologs ³
Mus musculus (house mouse):	Cd200r1 (CD200 receptor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CD200R1 (CD200 receptor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-214p13.9	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	XB5962421 [provisional]	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	69,392,943 - 69,427,213 (-)	NCBI		GRCr8
mRatBN7.2	11	55,886,937 - 55,921,217 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	55,887,717 - 55,921,285 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	64,701,896 - 64,734,611 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	57,363,755 - 57,396,462 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	56,434,097 - 56,466,769 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	60,848,161 - 60,882,470 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	60,848,131 - 60,882,379 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	64,962,558 - 64,994,987 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	57,427,237 - 57,459,716 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	57,484,825 - 57,517,305 (-)	NCBI
Celera	11	55,452,759 - 55,484,520 (-)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-diaminodiphenylmethane (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

daidzein (ISO)

daidzein 7-O-beta-D-glucoside (ISO)

dioxygen (EXP)

folic acid (ISO)

genistein (ISO)

genistein 7-O-beta-D-glucoside (ISO)

gentamycin (EXP)

glycitein (ISO)

glycitin (ISO)

inulin (ISO)

L-methionine (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (EXP,ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

testosterone (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

tremolite asbestos (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

heterotypic cell-cell adhesion (IMP,IPI)

negative regulation of interleukin-6 production (IGI)

negative regulation of macrophage migration (IGI)

negative regulation of neuroinflammatory response (IGI)

negative regulation of T cell migration (IGI)

regulation of neuroinflammatory response (IGI)

Cellular Component

cell surface (IDA,ISO)

external side of plasma membrane (IBA,ISO)

plasma membrane (ISO)

receptor complex (ISO)

Molecular Function

protein binding (ISO)

protein binding involved in heterotypic cell-cell adhesion (IPI)

signaling receptor activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	CNS inflammation and neuronal degeneration is aggravated by impaired CD200-CD200R-mediated macrophage silencing.	Meuth SG, etal., J Neuroimmunol. 2008 Feb;194(1-2):62-9. doi: 10.1016/j.jneuroim.2007.11.013.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Lymphoid/neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function.	Wright GJ, etal., Immunity 2000 Aug;13(2):233-42.
8.	The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans.	Wright GJ, etal., Immunology. 2001 Feb;102(2):173-9.

Additional References at PubMed

PMID:15274657	PMID:19151626	PMID:21471232	PMID:22053982	PMID:22342946	PMID:23382219	PMID:25569356	PMID:30006626	PMID:30032349	PMID:31078691	PMID:32394288	PMID:32473633
PMID:32664639	PMID:36565856	PMID:36591265	PMID:37971567	PMID:38237226

Genomics

Comparative Map Data

Cd200r1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	69,392,943 - 69,427,213 (-)	NCBI		GRCr8
mRatBN7.2	11	55,886,937 - 55,921,217 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	55,887,717 - 55,921,285 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	64,701,896 - 64,734,611 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	57,363,755 - 57,396,462 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	56,434,097 - 56,466,769 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	60,848,161 - 60,882,470 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	60,848,131 - 60,882,379 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	64,962,558 - 64,994,987 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	57,427,237 - 57,459,716 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	57,484,825 - 57,517,305 (-)	NCBI
Celera	11	55,452,759 - 55,484,520 (-)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI

CD200R1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	112,921,205 - 112,975,103 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	112,921,205 - 112,975,103 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	112,640,052 - 112,693,950 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	114,124,222 - 114,176,627 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	111,049,870 - 111,102,275 (-)	NCBI		Celera
Cytogenetic Map	3	q13.2	NCBI
HuRef	3	110,025,071 - 110,077,471 (-)	NCBI		HuRef
CHM1_1	3	112,605,064 - 112,657,469 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	115,642,153 - 115,696,046 (-)	NCBI		T2T-CHM13v2.0

Cd200r1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	44,586,141 - 44,615,341 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	44,586,099 - 44,615,341 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	44,765,736 - 44,794,977 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	44,765,736 - 44,794,978 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	44,765,849 - 44,795,090 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	44,685,124 - 44,714,310 (+)	NCBI		MGSCv36	mm8
Celera	16	45,131,563 - 45,160,813 (+)	NCBI		Celera
Cytogenetic Map	16	B4	NCBI
cM Map	16	29.08	NCBI

Cd200r1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955427	13,143,695 - 13,148,743 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC487977
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	17,332,986 - 17,357,301 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	17,436,279 - 17,460,591 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	17,577,294 - 17,601,611 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	33	17,381,692 - 17,406,001 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	17,429,158 - 17,453,448 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	17,978,760 - 18,003,078 (-)	NCBI		UU_Cfam_GSD_1.0

LOC103228312
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	67,862,368 - 67,902,875 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	67,862,783 - 67,901,872 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	98,576,511 - 98,618,733 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Cd200r1
128 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	88
Count of miRNA genes:	66
Interacting mature miRNAs:	69
Transcripts:	ENSRNOT00000002799
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
10755497	Bp388	Blood pressure QTL 388	2.76		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	19456205	76331918	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
1300130	Rf20	Renal function QTL 20	4.44		kidney glomerulus integrity trait (VT:0010546)	kidney glomerulus diameter (CMO:0001166)	11	29528418	60324829	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	111	91	90	59	25	59	6	217	96	91	45	58	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_023953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008768743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088612	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC109106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF231392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY583211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002799 ⟹ ENSRNOP00000002799

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	55,887,717 - 55,921,285 (-)	Ensembl
Rnor_6.0 Ensembl	11	60,848,131 - 60,882,379 (-)	Ensembl

RefSeq Acc Id:

NM_023953 ⟹ NP_076443

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	69,392,975 - 69,427,128 (-)	NCBI
mRatBN7.2	11	55,886,969 - 55,921,130 (-)	NCBI
Rnor_6.0	11	60,849,447 - 60,882,153 (-)	NCBI
Rnor_5.0	11	64,962,558 - 64,994,987 (-)	NCBI
RGSC_v3.4	11	57,427,237 - 57,459,716 (-)	RGD
Celera	11	55,452,759 - 55,484,520 (-)	RGD

Sequence:

show sequence

ATGCTCTGCTTTTGGAGAACTTCTCACGTAGCAGTACTCTTGATCTGGGGGGTCTTCGCGGCTG
AGTCAAGTTGTCCTGATAAGAATCAAACAATGCAGAACAATTCATCAACTATGACAGAAGTTAA
CACTACAGTGTTTGTACAGATGGGTAAAAAGGCTCTGCTCTGCTGCCCTTCTATTTCACTGACA
AAAGTAATATTAATAACATGGACAATAACCCTCAGAGGACAGCCTTCCTGCATAATATCCTACA
AAGCAGACACAAGGGAGACCCATGAAAGCAACTGCTCGGACAGAAGCATCACCTGGGCCTCCAC
ACCTGACCTCGCTCCTGACCTTCAGATCAGTGCAGTGGCCCTCCAGCATGAAGGGCGTTACTCA
TGTGATATAGCAGTACCTGACGGGAATTTCCAAAACATCTATGACCTCCAAGTGCTGGTGCCCC
CTGAAGTAACCCACTTTCCAGGGGAAAATAGAACTGCAGTTTGTGAGGCGATTGCAGGCAAACC
TGCTGCGCAGATCTCTTGGACGCCAGATGGGGATTGTGTCGCTAAGAATGAATCACACAGCAAT
GGCACCGTGACTGTCCGGAGCACATGCCACTGGGAGCAGAGCCACGTGTCTGTCGTGTTCTGTG
TTGTCTCTCACTTGACAACTGGTAACCAGTCTCTGTCTATAGAACTGGGTAGAGGGGGTGACCA
ATTATTAGGATCATACATTCAATACATCATCCCATCTATTATTATTTTGATCATCATAGGATGC
ATTTGTCTTTTGAAAATCAGTGGCTGCAGAAAATGTAAATTGCCAAAATCGGGAGCTACTCCAG
ATATTGAGGAGGATGAAATGCAGCCGTATGCTAGCTACACAGAGAAGAGCAATCCACTCTATGA
TACTGTGACCACGACGGAGGCACACCCAGCGTCACAAGGCAAAGTCAATGGCACAGACTGTCTT
ACTTTGTCAGCCATGGGAATCTAG

hide sequence

RefSeq Acc Id:

XM_006248347 ⟹ XP_006248409

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	69,392,943 - 69,427,212 (-)	NCBI
mRatBN7.2	11	55,886,937 - 55,921,217 (-)	NCBI
Rnor_6.0	11	60,848,161 - 60,882,470 (-)	NCBI
Rnor_5.0	11	64,962,558 - 64,994,987 (-)	NCBI

Sequence:

show sequence

AAGAGAGCCAATGGGCTGAAAGTAACCCACTTAGTCAGCTTCCTCTGTCTTTGCCTCACGGCTC
TGCACAGGAAATCTATTGCTGTGTCAAGTCCCAGAGAAGTTTCTTCGCTTCCAAGTTACTAGTC
AGACCAAAGCACGCTGAGTGGAAGGAGAGGGCAGGGAAGACAGGACTGCTCCCGGCTGATGGGT
TAAGAGGTGGGCTACCACGCAGAAGCCAACCCGAGAGCGGAGGGATCCTGGTCATGGTCACCGC
TGCTCCCCTACCTGTGAAGAGAAAGAGCACCGAGTGAGCCGCTGAAAACCAGAAAACCGAAATG
CTCTGCTTTTGGAGAACTTCTCACGTAGCAGTACTCTTGATCTGGGGGGTCTTCGCGGCTGAGT
CAAGTTGTCCTGATAAGAATCAAACAATGCAGAACAATTCATCAACTATGACAGAAGTTAACAC
TACAGTGTTTGTACAGATGGGTAAAAAGGCTCTGCTCTGCTGCCCTTCTATTTCACTGACAAAA
GTAATATTAATAACATGGACAATAACCCTCAGAGGACAGCCTTCCTGCATAATATCCTACAAAG
CAGACACAAGGGAGACCCATGAAAGCAACTGCTCGGACAGAAGCATCACCTGGGCCTCCACACC
TGACCTCGCTCCTGACCTTCAGATCAGTGCAGTGGCCCTCCAGCATGAAGGGCGTTACTCATGT
GATATAGCAGTACCTGACGGGAATTTCCAAAACATCTATGACCTCCAAGTGCTGGTGCCCCCTG
AAGTAACCCACTTTCCAGGGGAAAATAGAACTGCAGTTTGTGAGGCGATTGCAGGCAAACCTGC
TGCGCAGATCTCTTGGACGCCAGATGGGGATTGTGTCGCTAAGAATGAATCACACAGCAATGGC
ACCGTGACTGTCCGGAGCACATGCCACTGGGAGCAGAGCCACGTGTCTGTCGTGTTCTGTGTTG
TCTCTCACTTGACAACTGGTAACCAGTCTCTGTCTATAGAACTGGGTAGAGGGGGTGACCAATT
ATTAGGATCATACATTCAATACATCATCCCATCTATTATTATTTTGATCATCATAGGATGCATT
TGTCTTTTGAAAATCAGTGGCTGCAGGATGAAATGCAGCCGTATGCTAGCTACACAGAGAAGAG
CAATCCACTCTATGATACTGTGACCACGACGGAGGCACACCCAGCGTCACAAGGCAAAGTCAAT
GGCACAGACTGTCTTACTTTGTCAGCCATGGGAATCTAGAACCAAGGAAAAGAAGTCAAGAGAC
ATCATAATTACTGCTTTTCTTTCTTTAAACTTCTCCAATGGAGGGAAATTAGCTCTTCTGAAGT
TCTTAGAAAGCACAAATGTTCTAATGGATTTGCCTTTAAGTTCTTCTATCATTGGAAGTTTGGA
ATCTTTGCTGCTACCTGTTAATTCTAGGAAGAACTGATTTAATTATTACAAAGAAAGCACATTG
TTATGGTAAAATATCAAATTGTGCAATACAATGATGAAAACTGAGTTTCCTCAAGAAATAACTG
CAGAAGGAACAATCATTACTAAAGCATTTCATGTGAGTTCTTCCAAAAAAGAAAATCCCTGTGT
ATACGACATGATTATGGTATGTGTGTGCCTTTATATGTTTGTTTACAAATGTGTATATATGCAC
ACATCTGATTATCAAGACATCTCTGTCAAAAACTCACTGGCGTTCCAGATTTATGAAAGCTAAT
AAAGTGAGTATTGGAGATGTTTTTATATCTGTATATGTAAAACTACCTCATTCTTTTTAATGGC
TACATAAAATTCATGGTCCTTGGATGGGCATTTAGACTTTGTGTTGTATGTGGTATTAAATGAT
ACCATGTGGAATGTTTCTTGTGGTGAATCTCCGCATTATTTGAGTGCACCTGTGAGATAATTTC
TGTGAGTGTAATGGTCCTGTCAGTTGGAATGCGCTTTTATGATCAATAGATTAGTCAAACTGTG
TCAGTTTACATTTTCTCTAATTGTGTTTAATGTGACTTTCTCCATATTCTTATTCTTATGTTTT
TAATATCTTCACTTTCACCTTTTATACTTTCCATCTTTAATTAACCAGTTGGGTGATGTGTCTT
AAGGTTGTGATATTAACTTTATTATTTAATGGAACTGGATTCATATCTTTGGGTTTCATGTCCA
CAAAAGAGATAGAAAGCATTTGTAAAGACAGTATTTTCAACTCCTTGTATTACTACAAAAATGT
TGACATCTGATGCACAACAGTTTTATGGATGTTATGAATTGTGTGTTTTTAACATTCTATTCTG
ATGTACTTATAAGAGAGCAACTGTCTTTGAACTATATATGTAGGTGGGAGAACTTGGAGTACTT
TATGTGCTAATAGGATGGTAATGGGATGATATAACTTTTCCCTCCAGTTTTTTGGAGGGAAATA
TTAGGAATACATGTATTGATAATTTTTAGCATATATTTTTTAATTGTTAAAAATAAACCTGTTC
CCTTTATATCAGGAAAGATATTAAAAATGGATTTATTCATCTTAA

hide sequence

RefSeq Acc Id:

XM_008768743 ⟹ XP_008766965

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	69,392,943 - 69,427,212 (-)	NCBI
mRatBN7.2	11	55,886,937 - 55,921,217 (-)	NCBI
Rnor_6.0	11	60,848,161 - 60,882,468 (-)	NCBI

Sequence:

show sequence

GAGAGCCAATGGGCTGAAAGTAACCCACTTAGTCAGCTTCCTCTGTCTTTGCCTCACGGCTCTG
CACAGGAAATCTATTGCTGTGTCAAGTCCCAGAGAAGTTTCTTCGCTTCCAAGTTACTAGTCAG
ACCAAAGCACGCTGAGTGGAAGGAGAGGGCAGGGAAGACAGGACTGCTCCCGGCTGATGGGTTA
AGAGGTGGGCTACCACGCAGAAGCCAACCCGAGAGCGGAGGGATCCTGGTCATGGTCACCGCTG
CTCCCCTACCTGTGAAGAGAAAGAGCACCGAGTGAGCCGCTGAAAACCAGAAAACCGAAATGCT
CTGCTTTTGGAGAACTTCTCACGTAGCAGTACTCTTGATCTGGGGGGTCTTCGCGGCTGAGTCA
AGTTGTCCTGATAAGAATCAAACAATGCAGAACAATTCATCAACTATGACAGAAGTGTTTGTAC
AGATGGGTAAAAAGGCTCTGCTCTGCTGCCCTTCTATTTCACTGACAAAAGTAATATTAATAAC
ATGGACAATAACCCTCAGAGGACAGCCTTCCTGCATAATATCCTACAAAGCAGACACAAGGGAG
ACCCATGAAAGCAACTGCTCGGACAGAAGCATCACCTGGGCCTCCACACCTGACCTCGCTCCTG
ACCTTCAGATCAGTGCAGTGGCCCTCCAGCATGAAGGGCGTTACTCATGTGATATAGCAGTACC
TGACGGGAATTTCCAAAACATCTATGACCTCCAAGTGCTGGTGCCCCCTGAAGTAACCCACTTT
CCAGGGGAAAATAGAACTGCAGTTTGTGAGGCGATTGCAGGCAAACCTGCTGCGCAGATCTCTT
GGACGCCAGATGGGGATTGTGTCGCTAAGAATGAATCACACAGCAATGGCACCGTGACTGTCCG
GAGCACATGCCACTGGGAGCAGAGCCACGTGTCTGTCGTGTTCTGTGTTGTCTCTCACTTGACA
ACTGGTAACCAGTCTCTGTCTATAGAACTGGGTAGAGGGGGTGACCAATTATTAGGATCATACA
TTCAATACATCATCCCATCTATTATTATTTTGATCATCATAGGATGCATTTGTCTTTTGAAAAT
CAGTGGCTGCAGAAAATGTAAATTGCCAAAATCGGGAGCTACTCCAGATATTGAGGAGGATGAA
ATGCAGCCGTATGCTAGCTACACAGAGAAGAGCAATCCACTCTATGATACTGTGACCACGACGG
AGGCACACCCAGCGTCACAAGGCAAAGTCAATGGCACAGACTGTCTTACTTTGTCAGCCATGGG
AATCTAGAACCAAGGAAAAGAAGTCAAGAGACATCATAATTACTGCTTTTCTTTCTTTAAACTT
CTCCAATGGAGGGAAATTAGCTCTTCTGAAGTTCTTAGAAAGCACAAATGTTCTAATGGATTTG
CCTTTAAGTTCTTCTATCATTGGAAGTTTGGAATCTTTGCTGCTACCTGTTAATTCTAGGAAGA
ACTGATTTAATTATTACAAAGAAAGCACATTGTTATGGTAAAATATCAAATTGTGCAATACAAT
GATGAAAACTGAGTTTCCTCAAGAAATAACTGCAGAAGGAACAATCATTACTAAAGCATTTCAT
GTGAGTTCTTCCAAAAAAGAAAATCCCTGTGTATACGACATGATTATGGTATGTGTGTGCCTTT
ATATGTTTGTTTACAAATGTGTATATATGCACACATCTGATTATCAAGACATCTCTGTCAAAAA
CTCACTGGCGTTCCAGATTTATGAAAGCTAATAAAGTGAGTATTGGAGATGTTTTTATATCTGT
ATATGTAAAACTACCTCATTCTTTTTAATGGCTACATAAAATTCATGGTCCTTGGATGGGCATT
TAGACTTTGTGTTGTATGTGGTATTAAATGATACCATGTGGAATGTTTCTTGTGGTGAATCTCC
GCATTATTTGAGTGCACCTGTGAGATAATTTCTGTGAGTGTAATGGTCCTGTCAGTTGGAATGC
GCTTTTATGATCAATAGATTAGTCAAACTGTGTCAGTTTACATTTTCTCTAATTGTGTTTAATG
TGACTTTCTCCATATTCTTATTCTTATGTTTTTAATATCTTCACTTTCACCTTTTATACTTTCC
ATCTTTAATTAACCAGTTGGGTGATGTGTCTTAAGGTTGTGATATTAACTTTATTATTTAATGG
AACTGGATTCATATCTTTGGGTTTCATGTCCACAAAAGAGATAGAAAGCATTTGTAAAGACAGT
ATTTTCAACTCCTTGTATTACTACAAAAATGTTGACATCTGATGCACAACAGTTTTATGGATGT
TATGAATTGTGTGTTTTTAACATTCTATTCTGATGTACTTATAAGAGAGCAACTGTCTTTGAAC
TATATATGTAGGTGGGAGAACTTGGAGTACTTTATGTGCTAATAGGATGGTAATGGGATGATAT
AACTTTTCCCTCCAGTTTTTTGGAGGGAAATATTAGGAATACATGTATTGATAATTTTTAGCAT
ATATTTTTTAATTGTTAAAAATAAACCTGTTCCCTTTATATCAGGAAAGATATTAAAAATGGAT
TTATTCATCTTAA

hide sequence

RefSeq Acc Id:

XM_039088611 ⟹ XP_038944539

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	69,392,943 - 69,427,211 (-)	NCBI
mRatBN7.2	11	55,886,937 - 55,921,215 (-)	NCBI

RefSeq Acc Id:

XM_039088612 ⟹ XP_038944540

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	69,392,943 - 69,427,213 (-)	NCBI
mRatBN7.2	11	55,886,937 - 55,921,217 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_076443	(Get FASTA)	NCBI Sequence Viewer
	XP_006248409	(Get FASTA)	NCBI Sequence Viewer
	XP_008766965	(Get FASTA)	NCBI Sequence Viewer
	XP_038944539	(Get FASTA)	NCBI Sequence Viewer
	XP_038944540	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF98555	(Get FASTA)	NCBI Sequence Viewer
	AAS90843	(Get FASTA)	NCBI Sequence Viewer
	EDM11150	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002799.3
	ENSRNOP00055004099
	ENSRNOP00060009046
	ENSRNOP00065010140
GenBank Protein	Q9ES58	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_076443 ⟸ NM_023953
- Peptide Label:	precursor
- UniProtKB:	Q6PS97 (UniProtKB/Swiss-Prot), Q9ES58 (UniProtKB/Swiss-Prot), A6IQZ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVNTTVFVQMGKKALLCCPSISLT KVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYS CDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSN GTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGC ICLLKISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCL TLSAMGI hide sequence

RefSeq Acc Id:

XP_006248409 ⟸ XM_006248347

- Peptide Label:

isoform X4

- Sequence:

show sequence

MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVNTTVFVQMGKKALLCCPSISLT
KVILITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYS
CDIAVPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSN
GTVTVRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGC
ICLLKISGCRMKCSRMLATQRRAIHSMIL

hide sequence

RefSeq Acc Id:

XP_008766965 ⟸ XM_008768743

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLCFWRTSHVAVLLIWGVFAAESSCPDKNQTMQNNSSTMTEVFVQMGKKALLCCPSISLTKVIL
ITWTITLRGQPSCIISYKADTRETHESNCSDRSITWASTPDLAPDLQISAVALQHEGRYSCDIA
VPDGNFQNIYDLQVLVPPEVTHFPGENRTAVCEAIAGKPAAQISWTPDGDCVAKNESHSNGTVT
VRSTCHWEQSHVSVVFCVVSHLTTGNQSLSIELGRGGDQLLGSYIQYIIPSIIILIIIGCICLL
KISGCRKCKLPKSGATPDIEEDEMQPYASYTEKSNPLYDTVTTTEAHPASQGKVNGTDCLTLSA
MGI

hide sequence

Ensembl Acc Id:

ENSRNOP00000002799 ⟸ ENSRNOT00000002799

RefSeq Acc Id:	XP_038944540 ⟸ XM_039088612
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038944539 ⟸ XM_039088611
- Peptide Label:	isoform X2

Protein Domains

Ig-like Ig-like C2-type Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9ES58-F1-model_v2	AlphaFold	Q9ES58	1-327	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698146

Promoter ID:

EPDNEW_R8670

Type:

initiation region

Name:

Cd200r1_1

Description:

CD200 receptor 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	60,882,342 - 60,882,402	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61837	AgrOrtholog
BioCyc Gene	G2FUF-21358	BioCyc
Ensembl Genes	ENSRNOG00000039048	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00055003530	UniProtKB/Swiss-Prot
	ENSRNOG00060007303	UniProtKB/Swiss-Prot
	ENSRNOG00065008594	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000002799.6	UniProtKB/Swiss-Prot
	ENSRNOT00055005496	UniProtKB/Swiss-Prot
	ENSRNOT00060012001	UniProtKB/Swiss-Prot
	ENSRNOT00065013660	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	CD200R	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CD80_C2-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:64357	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	64357	ENTREZGENE
PANTHER	CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CELL SURFACE GLYCOPROTEIN OX2 RECEPTOR PRECURSOR	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam	C2-set_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cd200r1	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000039048	RatGTEx
	ENSRNOG00055003530	RatGTEx
	ENSRNOG00060007303	RatGTEx
	ENSRNOG00065008594	RatGTEx
Superfamily-SCOP	Immunoglobulin	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A6IQZ7	ENTREZGENE, UniProtKB/TrEMBL
	MO2R1_RAT	UniProtKB/Swiss-Prot
	Q6PS97	ENTREZGENE
	Q9ES58	ENTREZGENE
UniProt Secondary	Q6PS97	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-18	Cd200r1	CD200 receptor 1	Mox2r	antigen identified by monoclonal antibody MRC OX-2 receptor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Mox2r	antigen identified by monoclonal antibody MRC OX-2 receptor			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_function	receptor for OX2	61663
gene_physical_interaction	interacts with OX2	61663
gene_regulation	phosphorylated on tyrosine residues	61663

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD