Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-dexrazoxane | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Dexrazoxane results in increased expression of NDUFB4 mRNA | CTD | PMID:26873546 | (+)-dexrazoxane | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of NDUFB4 mRNA | CTD | PMID:26873546 | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NDUFB4 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NDUFB4 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of NDUFB4 mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NDUFB4 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin affects the methylation of NDUFB4 intron] which results in decreased expression of NDUFB4 mRNA | CTD | PMID:33017471 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NDUFB4 mRNA | CTD | PMID:32109520 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Ndufb4 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of NDUFB4 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of NDUFB4 protein | CTD | PMID:34186270 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of NDUFB4 mRNA | CTD | PMID:31881176 | aldrin | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Aldrin results in decreased expression of NDUFB4 mRNA | CTD | PMID:18579281 | all-trans-retinoic acid | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of NDUFB4 mRNA | CTD | PMID:33167477 | Aroclor 1254 | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of NDUFB4 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | ISO | NDUFB4 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to NDUFB4 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NDUFB4 mRNA | CTD | PMID:22228805 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NDUFB4 mRNA | CTD | PMID:28412506 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NDUFB4 mRNA | CTD | PMID:35550907 | bisphenol A | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NDUFB4 mRNA and bisphenol A results in increased expression of NDUFB4 protein | CTD | PMID:25047013 more ... | bisphenol A | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NDUFB4 mRNA | CTD | PMID:32156529 and PMID:38074096 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NDUFB4 mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | bisphenol A affects the expression of NDUFB4 mRNA | CTD | PMID:30903817 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of NDUFB4 mRNA | CTD | PMID:30903817 | capsaicin | decreases expression | EXP | | 6480464 | Capsaicin results in decreased expression of NDUFB4 mRNA | CTD | PMID:16278290 | copper(II) sulfate | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NDUFB4 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases methylation | ISO | NDUFB4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of NDUFB4 promoter | CTD | PMID:27989131 | dibutyl phthalate | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NDUFB4 mRNA | CTD | PMID:17361019 and PMID:21266533 | dioxygen | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of NDUFB4 mRNA | CTD | PMID:24205000 | disodium selenite | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of NDUFB4 mRNA | CTD | PMID:18175754 | doxorubicin | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of NDUFB4 mRNA | CTD | PMID:26873546 | doxorubicin | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NDUFB4 mRNA | CTD | PMID:29803840 | doxorubicin | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of NDUFB4 mRNA | CTD | PMID:26873546 | epoxiconazole | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of NDUFB4 mRNA | CTD | PMID:35436446 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of NDUFB4 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NDUFB4 mRNA | CTD | PMID:22206623 | FR900359 | increases phosphorylation | ISO | NDUFB4 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of NDUFB4 protein | CTD | PMID:37730182 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of NDUFB4 gene | CTD | PMID:22079235 | glyphosate | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of NDUFB4 protein | CTD | PMID:36608876 | hexane | decreases methylation | EXP | | 6480464 | n-hexane results in decreased methylation of NDUFB4 promoter | CTD | PMID:23740543 | ivermectin | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NDUFB4 protein | CTD | PMID:32959892 | lipopolysaccharide | multiple interactions | ISO | NDUFB4 (Homo sapiens) | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of NDUFB4 mRNA | CTD | PMID:31059760 | methylmercury chloride | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NDUFB4 mRNA | CTD | PMID:28001369 | monosodium L-glutamate | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of NDUFB4 mRNA | CTD | PMID:19001666 | ozone | multiple interactions | ISO | NDUFB4 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of NDUFB4 mRNA | CTD | PMID:35430440 | paracetamol | affects expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NDUFB4 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NDUFB4 mRNA | CTD | PMID:33387578 | paracetamol | multiple interactions | ISO | NDUFB4 (Homo sapiens) | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of NDUFB4 mRNA | CTD | PMID:31059760 | paracetamol | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NDUFB4 mRNA | CTD | PMID:29067470 and PMID:31059760 | perfluorohexanesulfonic acid | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of NDUFB4 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of NDUFB4 mRNA | CTD | PMID:20936131 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ndufb4 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of NDUFB4 mRNA and PPARA protein inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of NDUFB4 mRNA] | CTD | PMID:20936131 and PMID:36331819 | resveratrol | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | resveratrol results in increased expression of NDUFB4 mRNA | CTD | PMID:22610192 | rotenone | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Rotenone results in increased expression of NDUFB4 mRNA | CTD | PMID:18191903 | sodium arsenite | increases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of NDUFB4 mRNA | CTD | PMID:34032870 | T-2 toxin | multiple interactions | EXP | | 6480464 | T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4] | CTD | PMID:36863559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NDUFB4 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NDUFB4 mRNA | CTD | PMID:31150632 and PMID:33387578 | toluene | affects expression | EXP | | 6480464 | Toluene affects the expression of NDUFB4 mRNA | CTD | PMID:21827849 | triptonide | increases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | triptonide results in increased expression of NDUFB4 mRNA | CTD | PMID:33045310 | tunicamycin | decreases expression | ISO | Ndufb4 (Mus musculus) | 6480464 | Tunicamycin results in decreased expression of NDUFB4 mRNA | CTD | PMID:17127020 | valproic acid | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NDUFB4 mRNA | CTD | PMID:23179753 and PMID:25192806 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of NDUFB4 mRNA | CTD | PMID:23034163 | vincristine | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of NDUFB4 mRNA | CTD | PMID:23649840 | vorinostat | decreases expression | ISO | NDUFB4 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of NDUFB4 mRNA | CTD | PMID:27188386 | |