Ets2 (ETS proto-oncogene 2, transcription factor) - Rat Genome Database

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Gene: Ets2 (ETS proto-oncogene 2, transcription factor) Rattus norvegicus
Analyze
Symbol: Ets2
Name: ETS proto-oncogene 2, transcription factor
RGD ID: 1584977
Description: Enables DNA binding activity and nuclear glucocorticoid receptor binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Avian erythroblastosis virus E26 (v-ets) oncogene homolog 2; E26 avian leukemia oncogene 2, 3' domain; Ets2_mapped; protein C-ets-2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian); v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Edcs1
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,491,057 - 48,507,843 (+)NCBIGRCr8
mRatBN7.21135,021,536 - 35,038,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,021,596 - 35,038,319 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,678,909 - 43,695,695 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,350,288 - 36,367,074 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,495,961 - 35,512,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,075,709 - 36,092,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,075,709 - 36,092,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,606,999 - 39,623,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,014,047 - 36,030,833 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1133,421,839 - 33,438,625 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenhexamid  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
irinotecan  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (EXP,ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenol  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
retinyl acetate  (ISO)
rotenone  (ISO)
sarin  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
Tanshinone I  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)
plasma membrane  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Physical interaction and functional synergy between glucocorticoid receptor and Ets2 proteins for transcription activation of the rat cytochrome P-450c27 promoter. Mullick J, etal., J Biol Chem 2001 May 25;276(21):18007-17. Epub 2001 Feb 21.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1300077   PMID:1409581   PMID:11583620   PMID:11909962   PMID:12637547   PMID:16780588   PMID:16799155   PMID:19182667   PMID:20176728   PMID:22247964   PMID:23552073   PMID:25446535  


Genomics

Comparative Map Data
Ets2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81148,491,057 - 48,507,843 (+)NCBIGRCr8
mRatBN7.21135,021,536 - 35,038,322 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,021,596 - 35,038,319 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1143,678,909 - 43,695,695 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01136,350,288 - 36,367,074 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,495,961 - 35,512,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,075,709 - 36,092,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,075,709 - 36,092,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01139,606,999 - 39,623,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,014,047 - 36,030,833 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1133,421,839 - 33,438,625 (-)NCBICelera
Cytogenetic Map11q11NCBI
ETS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382138,805,183 - 38,824,955 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2138,805,183 - 38,824,955 (+)EnsemblGRCh38hg38GRCh38
GRCh372140,177,107 - 40,196,879 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362139,099,719 - 39,118,749 (+)NCBINCBI36Build 36hg18NCBI36
Build 342139,099,718 - 39,118,749NCBI
Celera2125,375,600 - 25,394,615 (+)NCBICelera
Cytogenetic Map21q22.2ENTREZGENE
HuRef2125,647,131 - 25,666,960 (+)NCBIHuRef
CHM1_12139,737,886 - 39,757,463 (+)NCBICHM1_1
T2T-CHM13v2.02137,188,973 - 37,208,712 (+)NCBIT2T-CHM13v2.0
Ets2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391695,503,274 - 95,522,093 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1695,502,942 - 95,522,095 (+)EnsemblGRCm39 Ensembl
GRCm381695,702,407 - 95,721,049 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1695,702,075 - 95,721,051 (+)EnsemblGRCm38mm10GRCm38
MGSCv371695,924,014 - 95,942,656 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361695,811,284 - 95,829,847 (+)NCBIMGSCv36mm8
Celera1696,781,092 - 96,799,213 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.64NCBI
Ets2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540737,747,000 - 37,765,237 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540737,747,152 - 37,764,170 (+)NCBIChiLan1.0ChiLan1.0
ETS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22234,907,852 - 34,929,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12129,766,719 - 29,786,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02125,158,457 - 25,178,035 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12138,505,685 - 38,527,651 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2138,512,835 - 38,527,651 (+)Ensemblpanpan1.1panPan2
ETS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13133,846,821 - 33,861,394 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3133,839,010 - 33,860,330 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3132,915,273 - 32,934,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03133,153,632 - 33,172,908 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3133,158,349 - 33,172,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13133,027,715 - 33,046,975 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03133,032,006 - 33,051,276 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03133,521,018 - 33,540,235 (+)NCBIUU_Cfam_GSD_1.0
Ets2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497133,210,523 - 33,223,117 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365004,244,604 - 4,257,265 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365004,244,706 - 4,257,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ETS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13202,468,405 - 202,484,608 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113202,464,341 - 202,483,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ETS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1282,751,196 - 82,770,051 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl282,757,930 - 82,770,165 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605410,604,412 - 10,623,391 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ets2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474525,096,337 - 25,110,123 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474525,096,587 - 25,113,953 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ets2
75 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:836
Count of miRNA genes:323
Interacting mature miRNAs:446
Transcripts:ENSRNOT00000002247
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat

Markers in Region
D11Mit1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21134,918,041 - 34,918,164 (-)MAPPERmRatBN7.2
mRatBN7.21134,918,041 - 34,918,164 (+)MAPPERmRatBN7.2
Rnor_6.01135,972,253 - 35,972,375NCBIRnor6.0
Rnor_6.01135,900,634 - 35,900,756NCBIRnor6.0
Rnor_5.01139,486,246 - 39,486,368UniSTSRnor5.0
RGSC_v3.41135,910,590 - 35,910,713RGDRGSC3.4
RGSC_v3.41135,910,591 - 35,910,713UniSTSRGSC3.4
RGSC_v3.11135,966,825 - 35,967,133RGD
Celera1133,540,645 - 33,540,767UniSTS
SHRSP x BN Map1111.5599RGD
SHRSP x BN Map1111.5599UniSTS
FHH x ACI Map1113.32RGD
Cytogenetic Map11q11UniSTS
RH143332  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,027,968 - 35,028,225 (+)MAPPERmRatBN7.2
Rnor_6.01136,082,142 - 36,082,398NCBIRnor6.0
Rnor_5.01139,613,432 - 39,613,688UniSTSRnor5.0
RGSC_v3.41136,020,480 - 36,020,736UniSTSRGSC3.4
Celera1133,431,936 - 33,432,192UniSTS
RH 3.4 Map11263.4UniSTS
Cytogenetic Map11q11UniSTS
RH140303  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,011,925 - 35,012,130 (+)MAPPERmRatBN7.2
Rnor_6.01136,066,098 - 36,066,302NCBIRnor6.0
Rnor_5.01139,597,388 - 39,597,592UniSTSRnor5.0
RGSC_v3.41136,004,436 - 36,004,640UniSTSRGSC3.4
Celera1133,448,031 - 33,448,235UniSTS
RH 3.4 Map11259.61UniSTS
Cytogenetic Map11q11UniSTS
AU022856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,038,059 - 35,038,308 (+)MAPPERmRatBN7.2
mRatBN7.22195,901,258 - 195,901,507 (+)MAPPERmRatBN7.2
Rnor_6.02211,055,234 - 211,055,482NCBIRnor6.0
Rnor_6.01136,092,233 - 36,092,481NCBIRnor6.0
Rnor_5.01139,623,523 - 39,623,771UniSTSRnor5.0
Rnor_5.02230,524,571 - 230,524,819UniSTSRnor5.0
RGSC_v3.42203,829,909 - 203,830,157UniSTSRGSC3.4
RGSC_v3.41136,030,571 - 36,030,819UniSTSRGSC3.4
Celera1133,421,853 - 33,422,101UniSTS
Celera2188,546,126 - 188,546,374UniSTS
Cytogenetic Map11q11UniSTS
Cytogenetic Map2q34UniSTS
RH139731  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,037,745 - 35,037,925 (+)MAPPERmRatBN7.2
Rnor_6.01136,091,919 - 36,092,098NCBIRnor6.0
Rnor_5.01139,623,209 - 39,623,388UniSTSRnor5.0
RGSC_v3.41136,030,257 - 36,030,436UniSTSRGSC3.4
Celera1133,422,236 - 33,422,415UniSTS
RH 3.4 Map11262.7UniSTS
Cytogenetic Map11q11UniSTS
ETV2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,035,107 - 35,036,192 (+)MAPPERmRatBN7.2
Rnor_6.01136,089,281 - 36,090,365NCBIRnor6.0
Rnor_5.01139,620,571 - 39,621,655UniSTSRnor5.0
RGSC_v3.41136,027,619 - 36,028,703UniSTSRGSC3.4
Celera1133,423,969 - 33,425,053UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000002247   ⟹   ENSRNOP00000002247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1135,021,596 - 35,036,878 (+)Ensembl
Rnor_6.0 Ensembl1136,075,709 - 36,092,495 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110500   ⟹   ENSRNOP00000079943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1135,021,872 - 35,038,319 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110658   ⟹   ENSRNOP00000084891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1135,024,236 - 35,038,319 (+)Ensembl
RefSeq Acc Id: NM_001107107   ⟹   NP_001100577
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,491,057 - 48,507,843 (+)NCBI
mRatBN7.21135,021,536 - 35,038,322 (+)NCBI
Rnor_6.01136,075,709 - 36,092,495 (+)NCBI
Rnor_5.01139,606,999 - 39,623,785 (+)NCBI
RGSC_v3.41136,014,047 - 36,030,833 (+)RGD
Celera1133,421,839 - 33,438,625 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248177   ⟹   XP_006248239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81148,491,311 - 48,507,840 (+)NCBI
mRatBN7.21135,021,827 - 35,038,321 (+)NCBI
Rnor_6.01136,075,950 - 36,092,494 (+)NCBI
Rnor_5.01139,606,999 - 39,623,785 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001100577   ⟸   NM_001107107
- UniProtKB: A6KPT9 (UniProtKB/TrEMBL),   A0A8I6GB76 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248239   ⟸   XM_006248177
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZS11 (UniProtKB/TrEMBL),   A0A8I6GB76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002247   ⟸   ENSRNOT00000002247
Ensembl Acc Id: ENSRNOP00000079943   ⟸   ENSRNOT00000110500
Ensembl Acc Id: ENSRNOP00000084891   ⟸   ENSRNOT00000110658
Protein Domains
ETS   PNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AAH4-F1-model_v2 AlphaFold D4AAH4 1-470 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698083
Promoter ID:EPDNEW_R8608
Type:initiation region
Name:Ets2_1
Description:ETS proto-oncogene 2, transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01136,075,745 - 36,075,805EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584977 AgrOrtholog
BioCyc Gene G2FUF-21723 BioCyc
Ensembl Genes ENSRNOG00000001647 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002247.7 UniProtKB/TrEMBL
  ENSRNOT00000110500.1 UniProtKB/TrEMBL
  ENSRNOT00000110658.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
InterPro Ets UniProtKB/TrEMBL
  Ets1_N_flank UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
  Transform_prot_C-ets-2 UniProtKB/TrEMBL
  Transforming_factor_C-ets UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:304063 UniProtKB/TrEMBL
NCBI Gene 304063 ENTREZGENE
PANTHER ETS-LIKE PROTEIN POINTED UniProtKB/TrEMBL
  PROTEIN C-ETS-2 UniProtKB/TrEMBL
  PTHR11849 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
  Ets1_N_flank UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PhenoGen Ets2 PhenoGen
PIRSF C-ets-2 UniProtKB/TrEMBL
  Transforming_factor_C-ets UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001647 RatGTEx
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SAM_homology UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
UniProt A0A8I5ZS11 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GB76 ENTREZGENE, UniProtKB/TrEMBL
  A6KPT7_RAT UniProtKB/TrEMBL
  A6KPT8_RAT UniProtKB/TrEMBL
  A6KPT9 ENTREZGENE, UniProtKB/TrEMBL
  A6KPU0_RAT UniProtKB/TrEMBL
  A6KPU1_RAT UniProtKB/TrEMBL
  A6KPU2_RAT UniProtKB/TrEMBL
  D4AAH4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Ets2  ETS proto-oncogene 2, transcription factor  Ets2  v-ets avian erythroblastosis virus E26 oncogene homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-01 Ets2  v-ets avian erythroblastosis virus E26 oncogene homolog 2  Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-25 Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)  Ets2  E26 avian leukemia oncogene 2, 3' domain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Ets2  E26 avian leukemia oncogene 2, 3' domain  Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)  Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)  Name updated 737654 APPROVED
2007-04-11 Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)  Ets2_mapped  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)  Data merged from RGD:2584 737654 APPROVED
2006-11-19 Ets2  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Ets2_mapped  v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)      Symbol and Name updated 1556543 APPROVED
2002-06-10 Ets2  Avian erythroblastosis virus E26 (v-ets) oncogene homolog 2      Symbol and Name status set to approved 70586 APPROVED