Gene: Ets2 (ETS proto-oncogene 2, transcription factor) Rattus norvegicus
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Symbol: Ets2
Name: ETS proto-oncogene 2, transcription factor
Description: ENCODES a protein that exhibits DNA binding; glucocorticoid receptor binding; DNA-binding transcription factor activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; ectodermal cell fate commitment (ortholog); mesoderm development (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil
AGR Description: Exhibits DNA binding activity and glucocorticoid receptor binding activity; involved in positive regulation of transcription by RNA polymerase II; predicted to localize to the cytosol, nucleoplasm, and plasma membrane; orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor).
Merged Description: Exhibits DNA binding activity and glucocorticoid receptor binding activity; involved in positive regulation of transcription by RNA polymerase II; predicted to localize to the cytosol, nucleoplasm, and plasma membrane; orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Avian erythroblastosis virus E26 (v-ets) oncogene homolog 2; E26 avian leukemia oncogene 2, 3' domain; Ets2_mapped; protein C-ets-2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian); v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) (mapped)
Orthologs:
Homo sapiens (human) : ETS2 (ETS proto-oncogene 2, transcription factor)  HGNC  Alliance
Mus musculus (house mouse) : Ets2 (E26 avian leukemia oncogene 2, 3' domain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ets2 (ETS proto-oncogene 2, transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ETS2 (ETS proto-oncogene 2, transcription factor)
Canis lupus familiaris (dog) : ETS2 (ETS proto-oncogene 2, transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ets2 (ETS proto-oncogene 2, transcription factor)
Sus scrofa (pig) : ETS2 (ETS proto-oncogene 2, transcription factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01136,075,709 - 36,092,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01139,606,999 - 39,623,785 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,014,047 - 36,030,833 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1133,421,839 - 33,438,625 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ets2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1584977
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.