Bss118 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bss118 (Bone structure and strength QTL 118) Rattus norvegicus

Symbol: Bss118
Name: Bone structure and strength QTL 118
RGD ID: 11528648
Trait: femur strength trait   (VT:0010010)    
Measurement Type: femur ultimate displacement   (CMO:0002719)    
LOD Score: 6.658
P Value: 2.2E-7
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,638,763 - 43,376,331RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01142,784,725 - 45,474,665RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01145,975,219 - 48,667,416RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41141,400,037 - 44,300,147RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: NAft:HS 



Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118Ratabnormal bone strength  IAGP 11528619 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118Ratfemur ultimate displacement  IDA 11528619 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118Ratcontrol condition  IDA 11528619 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118Ratbone three-point bending test  IDA 11528619 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118RatNAft:HS  IEA 11528619 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bss118Ratfemur strength trait  IDA 11528619 RGD 


#
Reference Title
Reference Citation
1. Fine mapping of bone structure and strength QTLs in heterogeneous stock rat. Alam I, etal., Bone. 2015 Dec;81:417-26. doi: 10.1016/j.bone.2015.08.013. Epub 2015 Aug 19.


1 to 20 of 70 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1304614Epha6Eph receptor A6113975750140708901Rat
1305535Arl6ARF like GTPase 6114071187840738254Rat
1305628Crybg3crystallin beta-gamma domain containing 3114074919840861753Rat
708521Riox2ribosomal oxygenase 2114086136540884782Rat
1584981Nlrp4a-ps1NLR family, pyrin domain containing 4A, pseudogene 1114088428140905699Rat
621564Gabrr3gamma-aminobutyric acid type A receptor subunit rho3114090281240955263Rat
1333369Or5ac25olfactory receptor family 5 subfamily AC member 25114099973441000654Rat
1333619Or5ac24olfactory receptor family 5 subfamily AC member 24114100899041009910Rat
1333309Or5ac23olfactory receptor family 5 subfamily AC member 23114101703341017950Rat
1332924Or5ac23bolfactory receptor family 5 subfamily AC member 23B114103367041034587Rat
1333081Or5ac22olfactory receptor family 5 subfamily AC member 22114105917041060087Rat
1334206Or5ac21olfactory receptor family 5 subfamily AC member 21114107561241076532Rat
1333204Or5ac20-ps1olfactory receptor family 5 subfamily AC member 20, pseudogene 1114111185341112768Rat
1334340Or5h26olfactory receptor family 5 subfamily H member 26114113428641135215Rat
1333449Or5h27olfactory receptor family 5 subfamily H member 27114115137241157144Rat
41029306LOC120095566olfactory receptor 5AC1-like114116051841161438Rat
1334226Or5ac19olfactory receptor family 5 subfamily AC member 19114118427841185201Rat
1333463Olr1537olfactory receptor 1537114121143641212356Rat
1332608Or5h27bolfactory receptor family 5 subfamily H member 27B114123137741232306Rat
1333239Or5h26bolfactory receptor family 5 subfamily H member 26B114124218241243111Rat

1 to 20 of 70 rows
1 to 20 of 53 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
40546D11Rat71156114094618840946344Ratregion
42950D11Rat109186114239671342396899Ratregion
41634D11Rat96153114191806341918216Ratregion
44880D11Got38250114297814042978390Ratregion
44881D11Got37259114327745143277710Ratregion
44884D11Got41213114315041143150624Ratregion
44889D11Wox10111114193600541936116Ratregion
44890D11Got35191114219155842191749Ratregion
1636377D11Uwm2142114297811942978261Ratregion
7193090D11Wox10111114193600541936116Ratregion
7206408mMECIR5250114069119340692710Ratregion
5028633RH125651246114188315441883400Ratregion
5029259RH144116223114069734740697570Ratregion
5030157BF389142183114293844042938623Ratregion
5025144AU015720227114336121343361440Ratregion
5025190RH127361208114158817641588384Ratregion
5025850RH129929201114323236143232562Ratregion
5051579AW489850121114188422041884341Ratregion
5056525RH144429157114336048443360640Ratregion
5057402AA945780136114188339041883526Ratregion
1 to 20 of 53 rows

Flank 1: (rs107420884)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21140,638,763 - 40,638,763RGD
Rnor_6.01142,784,725 - 42,784,725RGD
Peak: (rs105204296)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21141,072,080 - 41,072,080RGD
Rnor_6.01145,611,977 - 45,611,977RGD
Flank 2: (rs198448974)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21143,376,331 - 43,376,331RGD
Rnor_6.01145,474,665 - 45,474,665RGD


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
11528648Bss118Bone structure and strength QTL 1186.6582e-07femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)114063876343376331Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat

1 to 10 of 18 rows


Note Type Note Reference
qtl_general number of animals used: 1524 HS rats (728 male, 796 female) were used. 11528619
qtl_general measurement method: Rats on a standard diet were euthanized at 17 to 20 weeks of age, and right femurs were analyzed using a material testing machine (Alliance RT/5,MTS Systems Corp., Eden Prairie, USA). 11528619