Epha6 (Eph receptor A6) - Rat Genome Database

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Gene: Epha6 (Eph receptor A6) Rattus norvegicus
Analyze
Symbol: Epha6
Name: Eph receptor A6
RGD ID: 1304614
Description: Predicted to have transmembrane-ephrin receptor activity. Predicted to be involved in axon guidance; positive regulation of kinase activity; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to several cellular components, including integral component of plasma membrane; neuron projection; and nucleoplasm. Orthologous to human EPHA6 (EPH receptor A6); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 6-propyl-2-thiouracil; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: EHK-2; Ehk2; EPH homology kinase 2; ephrin type-A receptor 6; tyrosine-protein kinase receptor EHK-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21139,757,870 - 40,708,901 (+)NCBI
Rnor_6.01141,867,607 - 42,843,800 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01145,066,461 - 46,035,688 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41140,551,554 - 41,458,539 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11140,597,889 - 41,024,933 (+)NCBI
Celera1139,606,772 - 40,545,970 (+)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7504232   PMID:15057822  


Genomics

Comparative Map Data
Epha6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21139,757,870 - 40,708,901 (+)NCBI
Rnor_6.01141,867,607 - 42,843,800 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01145,066,461 - 46,035,688 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41140,551,554 - 41,458,539 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11140,597,889 - 41,024,933 (+)NCBI
Celera1139,606,772 - 40,545,970 (+)NCBICelera
Cytogenetic Map11q12NCBI
EPHA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl396,814,581 - 97,752,460 (+)EnsemblGRCh38hg38GRCh38
GRCh38396,814,581 - 97,761,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37396,533,438 - 97,480,376 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36398,016,115 - 98,950,476 (+)NCBINCBI36hg18NCBI36
Celera394,916,109 - 95,857,365 (+)NCBI
Cytogenetic Map3q11.2NCBI
HuRef393,902,924 - 94,837,692 (+)NCBIHuRef
CHM1_1396,496,480 - 97,430,819 (+)NCBICHM1_1
Epha6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391659,473,424 - 60,431,196 (-)NCBIGRCm39mm39
GRCm39 Ensembl1659,473,846 - 60,425,894 (-)Ensembl
GRCm381659,641,433 - 60,610,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1659,653,483 - 60,605,531 (-)EnsemblGRCm38mm10GRCm38
MGSCv371659,653,309 - 60,605,357 (-)NCBIGRCm37mm9NCBIm37
MGSCv361659,595,739 - 60,547,503 (-)NCBImm8
Celera1660,004,715 - 60,923,397 (-)NCBICelera
Cytogenetic Map16C1.3NCBI
Epha6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955407400,745 - 1,220,538 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955407398,415 - 1,220,542 (-)NCBIChiLan1.0ChiLan1.0
EPHA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13100,562,841 - 101,504,222 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3100,734,791 - 101,503,805 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0393,881,686 - 94,819,563 (+)NCBIMhudiblu_PPA_v0panPan3
EPHA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1333,990,346 - 4,786,070 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl334,517,039 - 4,684,336 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha334,093,700 - 4,967,547 (+)NCBI
ROS_Cfam_1.0334,023,454 - 4,896,341 (+)NCBI
UMICH_Zoey_3.1333,901,331 - 4,772,858 (+)NCBI
UNSW_CanFamBas_1.0333,961,065 - 4,833,214 (+)NCBI
UU_Cfam_GSD_1.0334,235,497 - 5,107,565 (+)NCBI
Epha6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602152,451,572 - 153,234,891 (-)NCBI
SpeTri2.0NW_0049366662,280,811 - 3,063,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13162,569,479 - 163,443,646 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113162,568,835 - 163,445,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213173,570,910 - 173,735,724 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHA6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12282,960,714 - 83,914,993 (-)NCBI
Epha6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247899,279,440 - 10,211,840 (+)NCBI

Position Markers
D11Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,434,750 - 42,434,998NCBIRnor6.0
Rnor_5.01145,623,663 - 45,623,911UniSTSRnor5.0
RGSC_v3.41141,127,119 - 41,127,368RGDRGSC3.4
RGSC_v3.41141,127,120 - 41,127,368UniSTSRGSC3.4
RGSC_v3.11141,184,708 - 41,184,957RGD
Celera1140,147,720 - 40,147,968UniSTS
FHH x ACI Map1116.5799UniSTS
FHH x ACI Map1116.5799RGD
Cytogenetic Map11q12UniSTS
D11Got84  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,783,879 - 42,783,981NCBIRnor6.0
Rnor_5.01145,974,373 - 45,974,475UniSTSRnor5.0
RGSC_v3.41141,399,190 - 41,399,293RGDRGSC3.4
RGSC_v3.41141,399,191 - 41,399,293UniSTSRGSC3.4
RGSC_v3.11141,456,780 - 41,456,882RGD
Celera1140,479,883 - 40,479,985UniSTS
RH 3.4 Map11295.5RGD
RH 3.4 Map11295.5UniSTS
RH 2.0 Map11315.1RGD
Cytogenetic Map11q12UniSTS
RH144116  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,843,946 - 42,844,168NCBIRnor6.0
Rnor_5.01146,034,440 - 46,034,662UniSTSRnor5.0
RGSC_v3.41141,458,620 - 41,458,842UniSTSRGSC3.4
Celera1140,539,323 - 40,539,545UniSTS
RH 3.4 Map11292.6UniSTS
Cytogenetic Map11q12UniSTS
BF415441  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,104,992 - 42,105,105NCBIRnor6.0
Rnor_5.01145,302,005 - 45,302,118UniSTSRnor5.0
RGSC_v3.41140,770,869 - 40,770,982UniSTSRGSC3.4
Celera1139,827,166 - 39,827,279UniSTS
RH 3.4 Map11293.4UniSTS
Cytogenetic Map11q12UniSTS
RH144183  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01141,866,965 - 41,867,224NCBIRnor6.0
Rnor_5.01145,065,856 - 45,066,115UniSTSRnor5.0
RGSC_v3.41140,549,431 - 40,549,690UniSTSRGSC3.4
Celera1139,606,130 - 39,606,389UniSTS
RH 3.4 Map11292.7UniSTS
Cytogenetic Map11q12UniSTS
AU049238  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,258,777 - 42,258,950NCBIRnor6.0
Rnor_5.01145,454,287 - 45,454,460UniSTSRnor5.0
RGSC_v3.41140,953,141 - 40,953,314UniSTSRGSC3.4
Celera1139,977,135 - 39,977,308UniSTS
Cytogenetic Map11q12UniSTS
mMECIR525  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01142,837,784 - 42,839,300NCBIRnor6.0
Rnor_5.01146,028,278 - 46,029,794UniSTSRnor5.0
Celera1140,533,155 - 40,534,669UniSTS
Cytogenetic Map11q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11172720192Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)1132503169342559Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11935127454351274Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111136730644444347Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111632197346583360Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111947517979734728Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)112194422966944229Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)112194422966944229Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)112204314944444112Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112540112970401129Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112572003870720038Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112572003870720038Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112831466586994795Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113043533963186373Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)113043533986714631Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113215552082443118Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113590063480900634Rat
11528648Bss118Bone structure and strength QTL 1186.6580.00000022femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)114278472545474665Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:74
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000047310
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008768648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_008768648   ⟹   XP_008766870
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,667 - 42,309,822 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768650   ⟹   XP_008766872
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,664 - 42,694,366 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008776508   ⟹   XP_008774730
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,832 - 40,023,721 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008776514   ⟹   XP_008774736
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,669,285 - 40,545,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008776518   ⟹   XP_008774740
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,829 - 40,407,976 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598104   ⟹   XP_017453593
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21139,757,870 - 40,708,901 (+)NCBI
Rnor_6.01141,867,608 - 42,843,800 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598105   ⟹   XP_017453594
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,667 - 42,321,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598106   ⟹   XP_017453595
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,669 - 42,282,956 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598107   ⟹   XP_017453596
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,607 - 42,059,579 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598108   ⟹   XP_017453597
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01141,867,664 - 42,057,040 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604293   ⟹   XP_017459782
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,774 - 40,545,970 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604294   ⟹   XP_017459783
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,832 - 40,035,161 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604295   ⟹   XP_017459784
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,834 - 39,996,958 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604296   ⟹   XP_017459785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,772 - 39,782,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017604297   ⟹   XP_017459786
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1139,606,829 - 39,780,156 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088720   ⟹   XP_038944648
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21139,792,037 - 40,708,901 (+)NCBI
RefSeq Acc Id: XM_039088721   ⟹   XP_038944649
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21139,792,040 - 40,708,901 (+)NCBI
RefSeq Acc Id: XM_039088722   ⟹   XP_038944650
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21139,758,188 - 40,708,901 (+)NCBI
Protein Sequences
Protein RefSeqs XP_017453593 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944648 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944649 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944650 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P54758 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008774736   ⟸   XM_008776514
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008774740   ⟸   XM_008776518
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008766872   ⟸   XM_008768650
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017459785   ⟸   XM_017604296
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017459782   ⟸   XM_017604293
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_017459786   ⟸   XM_017604297
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017459783   ⟸   XM_017604294
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008774730   ⟸   XM_008776508
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017459784   ⟸   XM_017604295
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017453596   ⟸   XM_017598107
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_017453593   ⟸   XM_017598104
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017453597   ⟸   XM_017598108
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_017453594   ⟸   XM_017598105
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008766870   ⟸   XM_008768648
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017453595   ⟸   XM_017598106
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_038944650   ⟸   XM_039088722
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944648   ⟸   XM_039088720
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944649   ⟸   XM_039088721
- Peptide Label: isoform X3
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304614 AgrOrtholog
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.60.120.260 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro EPH-A6_SAM UniProtKB/Swiss-Prot
  Eph_TM UniProtKB/Swiss-Prot
  EphA6_rcpt_lig-bd UniProtKB/Swiss-Prot
  Ephrin_rcpt_lig-bd_dom UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_ephrin_rcpt UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_V_CS UniProtKB/Swiss-Prot
NCBI Gene 29202 ENTREZGENE
Pfam EphA2_TM UniProtKB/Swiss-Prot
  Ephrin_lbd UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
PhenoGen Epha6 PhenoGen
PIRSF TyrPK_ephrin_receptor UniProtKB/Swiss-Prot
PRINTS TYRKINASE UniProtKB/Swiss-Prot
PROSITE EGF_2 UniProtKB/Swiss-Prot
  EPH_LBD UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_1 UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_2 UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
SMART EPH_lbd UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
UniProt EPHA6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Epha6  Eph receptor A6   Epha6_predicted  Eph receptor A6 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Epha6_predicted  Eph receptor A6 (predicted)      Symbol and Name status set to approved 70820 APPROVED