Krtap24-1 (keratin associated protein 24-1) - Rat Genome Database

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Gene: Krtap24-1 (keratin associated protein 24-1) Rattus norvegicus
Analyze
Symbol: Krtap24-1
Name: keratin associated protein 24-1
RGD ID: 2320810
Description: Predicted to enable structural molecule activity. Predicted to be located in cytosol and keratin filament. Orthologous to human KRTAP24-1 (keratin associated protein 24-1); INTERACTS WITH acrylamide (ortholog); aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical protein LOC100364550; keratin-associated protein 24-1; LOC100364550
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,418,239 - 41,420,789 (-)NCBIGRCr8
mRatBN7.21127,932,015 - 27,936,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1127,932,785 - 27,933,531 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01128,582,189 - 28,584,930 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,582,897 - 28,583,643 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,202,221 - 32,203,327 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1127,647,550 - 27,650,291 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Krtap24-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81141,418,239 - 41,420,789 (-)NCBIGRCr8
mRatBN7.21127,932,015 - 27,936,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1127,932,785 - 27,933,531 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01128,582,189 - 28,584,930 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1128,582,897 - 28,583,643 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01132,202,221 - 32,203,327 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1127,647,550 - 27,650,291 (-)NCBICelera
Cytogenetic Map11q11NCBI
KRTAP24-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,281,309 - 30,282,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,281,309 - 30,282,950 (-)EnsemblGRCh38hg38GRCh38
GRCh372131,653,627 - 31,655,268 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,575,498 - 30,577,147 (-)NCBINCBI36Build 36hg18NCBI36
Celera2116,836,766 - 16,838,415 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,062,591 - 17,064,240 (-)NCBIHuRef
CHM1_12131,215,383 - 31,217,032 (-)NCBICHM1_1
T2T-CHM13v2.02128,647,180 - 28,648,821 (-)NCBIT2T-CHM13v2.0
Krtap24-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391688,407,597 - 88,409,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1688,407,593 - 88,409,167 (-)EnsemblGRCm39 Ensembl
GRCm381688,610,709 - 88,612,279 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1688,610,705 - 88,612,279 (-)EnsemblGRCm38mm10GRCm38
MGSCv371688,610,954 - 88,612,524 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361688,499,325 - 88,501,239 (-)NCBIMGSCv36mm8
Celera1688,815,197 - 88,816,767 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.32NCBI
LOC102029364
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540729,623,389 - 29,624,347 (-)NCBIChiLan1.0ChiLan1.0
LOC100988669
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22226,451,961 - 26,454,199 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12121,307,623 - 21,309,841 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02116,702,155 - 16,703,794 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12130,086,986 - 30,088,625 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2130,087,843 - 30,088,607 (-)Ensemblpanpan1.1panPan2
KRTAP24-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13125,132,271 - 25,166,568 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3125,144,046 - 25,144,807 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3125,124,829 - 25,157,486 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03125,249,167 - 25,279,603 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3125,258,714 - 25,259,475 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13125,196,374 - 25,229,076 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03125,208,338 - 25,240,512 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03125,672,573 - 25,702,873 (-)NCBIUU_Cfam_GSD_1.0
LOC101968614
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497125,616,767 - 25,618,357 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493650011,849,488 - 11,850,234 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRTAP24-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13193,630,813 - 193,631,574 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113193,629,958 - 193,633,397 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213204,233,038 - 204,234,672 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC119621514
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660714,526,547 - 4,528,175 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101708039
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474518,344,446 - 18,345,186 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Krtap24-1
13 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000071034
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system reproductive system appendage
High
Medium
Low 5
Below cutoff 1 2 1 1 1 2 2 4 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000071034   ⟹   ENSRNOP00000065645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1127,932,785 - 27,933,531 (-)Ensembl
Rnor_6.0 Ensembl1128,582,897 - 28,583,643 (-)Ensembl
RefSeq Acc Id: XM_003751011   ⟹   XP_003751059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81141,418,239 - 41,420,789 (-)NCBI
mRatBN7.21127,932,015 - 27,936,047 (-)NCBI
Rnor_6.01128,582,189 - 28,584,930 (-)NCBI
Rnor_5.01132,202,221 - 32,203,327 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003751059 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065645
  ENSRNOP00000065645.1
Reference Protein Sequences
RefSeq Acc Id: XP_003751059   ⟸   XM_003751011
- UniProtKB: M0R854 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000065645   ⟸   ENSRNOT00000071034

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R854-F1-model_v2 AlphaFold M0R854 1-248 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320810 AgrOrtholog
BioCyc Gene G2FUF-22027 BioCyc
Ensembl Genes ENSRNOG00000048374 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071034.2 UniProtKB/TrEMBL
InterPro Keratin_matx UniProtKB/TrEMBL
  PMG UniProtKB/TrEMBL
KEGG Report rno:100364550 UniProtKB/TrEMBL
NCBI Gene 100364550 ENTREZGENE
PANTHER KERATIN-ASSOCIATED PROTEIN 24-1 UniProtKB/TrEMBL
  PTHR23260 UniProtKB/TrEMBL
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap24-1 PhenoGen
RatGTEx ENSRNOG00000048374 RatGTEx
UniProt M0R854 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-07 Krtap24-1  keratin associated protein 24-1  LOC100364550  hypothetical protein LOC100364550  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100364550  hypothetical protein LOC100364550      Symbol and Name status set to provisional 70820 PROVISIONAL