Cbr3 (carbonyl reductase 3) - Rat Genome Database

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Gene: Cbr3 (carbonyl reductase 3) Rattus norvegicus
Analyze
Symbol: Cbr3
Name: carbonyl reductase 3
RGD ID: 1309728
Description: Enables 3-keto sterol reductase activity and carbonyl reductase (NADPH) activity. Involved in phylloquinone catabolic process. Predicted to be located in cytosol and nucleoplasm. Orthologous to human CBR3 (carbonyl reductase 3); PARTICIPATES IN doxorubicin pharmacokinetics pathway; arachidonic acid metabolic pathway; INTERACTS WITH 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: carbonyl reductase [NADPH] 3; LOC304078; monomeric carbonyl reductase 3; quinone reductase CBR3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,478,295 - 46,486,555 (+)NCBIGRCr8
mRatBN7.21133,008,615 - 33,016,877 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,008,615 - 33,016,875 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,662,664 - 41,670,924 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01134,334,206 - 34,342,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01133,484,246 - 33,492,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01133,909,417 - 33,917,674 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1133,909,439 - 33,917,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,500,661 - 37,508,918 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41133,913,961 - 33,922,221 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11133,961,819 - 33,978,463 (+)NCBI
Celera1135,427,193 - 35,435,432 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-palmitoylglycerol  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
9,10-phenanthroquinone  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alvocidib  (ISO)
andrographolide  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
captan  (ISO)
celastrol  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
cobicistat  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
dextran sulfate  (ISO)
dibenzoylmethane  (ISO)
diethyl maleate  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
Ethyl malonate  (ISO)
fenamidone  (ISO)
folic acid  (ISO)
folpet  (ISO)
furan  (ISO)
gedunin  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glutathione  (ISO)
glycidol  (ISO)
guggulsterone  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
isatin  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
metacetamol  (ISO)
methapyrilene  (ISO)
methoxyacetic acid  (ISO)
methyl methacrylate  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
methylphenidate  (ISO)
microcystin-LR  (ISO)
Monobutylphthalate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-Nitrosopyrrolidine  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
O-methyleugenol  (ISO)
oxcarbazepine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
trichloroethene  (EXP)
Triptolide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO,ISS)
nucleoplasm  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Hippocampal protein expression is differentially affected by chronic paroxetine treatment in adolescent and adult rats: a possible mechanism of "paradoxical" antidepressant responses in young persons. Karanges EA, etal., Front Pharmacol. 2013 Jul 8;4:86. doi: 10.3389/fphar.2013.00086. eCollection 2013.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Investigation of the role of the amino acid residue at position 230 for catalysis in monomeric carbonyl reductase 3. Miura T, etal., Chem Biol Interact. 2009 Mar 16;178(1-3):211-4. Epub 2008 Oct 15.
6. New developments in anthracycline-induced cardiotoxicity. Mordente A, etal., Curr Med Chem. 2009;16(13):1656-72.
7. Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy. Ohkura-Hada S, etal., Open Dent J. 2008;2:78-88. Epub 2008 Jun 9.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Doxorubicin pathways: pharmacodynamics and adverse effects. Thorn CF, etal., Pharmacogenet Genomics. 2011 Jul;21(7):440-6. doi: 10.1097/FPC.0b013e32833ffb56.
Additional References at PubMed
PMID:12477932   PMID:18493841   PMID:22664934   PMID:23227193  


Genomics

Comparative Map Data
Cbr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,478,295 - 46,486,555 (+)NCBIGRCr8
mRatBN7.21133,008,615 - 33,016,877 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,008,615 - 33,016,875 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,662,664 - 41,670,924 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01134,334,206 - 34,342,467 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01133,484,246 - 33,492,418 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01133,909,417 - 33,917,674 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1133,909,439 - 33,917,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,500,661 - 37,508,918 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41133,913,961 - 33,922,221 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11133,961,819 - 33,978,463 (+)NCBI
Celera1135,427,193 - 35,435,432 (-)NCBICelera
Cytogenetic Map11q11NCBI
CBR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382136,135,079 - 36,146,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2136,135,079 - 36,146,562 (+)EnsemblGRCh38hg38GRCh38
GRCh372137,507,377 - 37,518,860 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,429,133 - 36,440,730 (+)NCBINCBI36Build 36hg18NCBI36
Build 342136,364,264 - 36,440,724NCBI
Celera2122,706,132 - 22,717,559 (+)NCBICelera
Cytogenetic Map21q22.12NCBI
HuRef2122,984,935 - 22,996,359 (+)NCBIHuRef
CHM1_12137,069,046 - 37,080,642 (+)NCBICHM1_1
T2T-CHM13v2.02134,518,104 - 34,529,412 (+)NCBIT2T-CHM13v2.0
Cbr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391693,480,107 - 93,487,879 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1693,480,103 - 93,487,878 (+)EnsemblGRCm39 Ensembl
GRCm381693,683,219 - 93,690,991 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1693,683,215 - 93,690,990 (+)EnsemblGRCm38mm10GRCm38
MGSCv371693,683,464 - 93,691,236 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361693,571,759 - 93,579,527 (+)NCBIMGSCv36mm8
Celera1694,777,963 - 94,785,655 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1654.58NCBI
Cbr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540735,419,674 - 35,428,270 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540735,419,674 - 35,428,270 (+)NCBIChiLan1.0ChiLan1.0
CBR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22232,256,031 - 32,267,414 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12127,115,995 - 27,128,098 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02122,505,647 - 22,516,938 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12135,865,374 - 35,876,717 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2135,865,374 - 35,876,717 (+)Ensemblpanpan1.1panPan2
CBR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13131,416,441 - 31,423,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3131,416,333 - 31,423,739 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3130,472,787 - 30,480,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03130,713,351 - 30,720,605 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3130,713,139 - 30,720,547 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13130,585,631 - 30,592,893 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03130,599,689 - 30,606,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03131,090,527 - 31,097,817 (+)NCBIUU_Cfam_GSD_1.0
Cbr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497130,998,820 - 31,006,047 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365006,458,721 - 6,591,928 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365006,461,776 - 6,469,063 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13199,830,668 - 199,840,442 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113199,830,690 - 199,840,444 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213209,842,863 - 209,852,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CBR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1280,158,842 - 80,164,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl280,158,806 - 80,164,248 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660547,988,123 - 7,999,978 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474527,294,222 - 27,305,109 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474527,298,714 - 27,305,606 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cbr3
35 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:24
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000002310
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat

Markers in Region
RH127062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,016,611 - 33,016,857 (+)MAPPERmRatBN7.2
Rnor_6.01133,917,411 - 33,917,656NCBIRnor6.0
Rnor_5.01137,508,655 - 37,508,900UniSTSRnor5.0
RGSC_v3.41133,921,958 - 33,922,203UniSTSRGSC3.4
Celera1135,427,211 - 35,427,456UniSTS
Cytogenetic Map11q11UniSTS
RH137117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,016,634 - 33,016,817 (+)MAPPERmRatBN7.2
Rnor_6.01133,917,434 - 33,917,616NCBIRnor6.0
Rnor_5.01137,508,678 - 37,508,860UniSTSRnor5.0
RGSC_v3.41133,921,981 - 33,922,163UniSTSRGSC3.4
Celera1135,427,251 - 35,427,433UniSTS
RH 3.4 Map1697.8UniSTS
Cytogenetic Map11q11UniSTS
RH137712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21133,014,448 - 33,014,596 (+)MAPPERmRatBN7.2
Rnor_6.01133,915,248 - 33,915,395NCBIRnor6.0
Rnor_5.01137,506,492 - 37,506,639UniSTSRnor5.0
RGSC_v3.41133,919,795 - 33,919,942UniSTSRGSC3.4
Celera1135,429,472 - 35,429,619UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 2 1 12 6
Low 43 54 40 18 40 8 11 74 35 29 5 8
Below cutoff 1 1 1

Sequence


RefSeq Acc Id: ENSRNOT00000002310   ⟹   ENSRNOP00000002310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,008,615 - 33,016,875 (+)Ensembl
Rnor_6.0 Ensembl1133,909,439 - 33,917,674 (+)Ensembl
RefSeq Acc Id: NM_001107110   ⟹   NP_001100580
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81146,478,295 - 46,486,555 (+)NCBI
mRatBN7.21133,008,615 - 33,016,875 (+)NCBI
Rnor_6.01133,909,417 - 33,917,674 (+)NCBI
Rnor_5.01137,500,661 - 37,508,918 (+)NCBI
RGSC_v3.41133,913,961 - 33,922,221 (+)RGD
Celera1135,427,193 - 35,435,432 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100580 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66553 (Get FASTA)   NCBI Sequence Viewer  
  B2GV72 (Get FASTA)   NCBI Sequence Viewer  
  EDL76737 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002310
  ENSRNOP00000002310.4
RefSeq Acc Id: NP_001100580   ⟸   NM_001107110
- UniProtKB: B2GV72 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002310   ⟸   ENSRNOT00000002310

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2GV72-F1-model_v2 AlphaFold B2GV72 1-277 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698073
Promoter ID:EPDNEW_R8598
Type:initiation region
Name:Cbr3_1
Description:carbonyl reductase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01133,909,439 - 33,909,499EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309728 AgrOrtholog
BioCyc Gene G2FUF-21788 BioCyc
Ensembl Genes ENSRNOG00000001701 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002310 ENTREZGENE
  ENSRNOT00000002310.7 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7310545 IMAGE-MGC_LOAD
InterPro CBR1-like UniProtKB/Swiss-Prot
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report rno:304078 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188162 IMAGE-MGC_LOAD
NCBI Gene 304078 ENTREZGENE
PANTHER CARBONYL REDUCTASE 1-RELATED UniProtKB/Swiss-Prot
  CARBONYL REDUCTASE [NADPH] 3 UniProtKB/Swiss-Prot
Pfam adh_short UniProtKB/Swiss-Prot
PharmGKB CBR3 RGD
PhenoGen Cbr3 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
  SDRFAMILY UniProtKB/Swiss-Prot
PROSITE ADH_SHORT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001701 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt B2GV72 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Cbr3  carbonyl reductase 3   Cbr3_predicted  carbonyl reductase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cbr3_predicted  carbonyl reductase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED