Hspa13 (heat shock protein family A (Hsp70) member 13) - Rat Genome Database

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Gene: Hspa13 (heat shock protein family A (Hsp70) member 13) Rattus norvegicus
Analyze
Symbol: Hspa13
Name: heat shock protein family A (Hsp70) member 13
RGD ID: 3775
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to localize to mitochondrion. Orthologous to human HSPA13 (heat shock protein family A (Hsp70) member 13); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heat shock 70 kDa protein 13; heat shock protein 13; heat shock protein 70 family, member 13; heat shock protein 70kDa family, member 13; microsomal stress 70 protein ATPase core; microsomal stress-70 protein ATPase core; Stch; stress 70 protein chaperone microsome-associated 60 kDa protein; stress 70 protein chaperone microsome-associated 60kD human homolog; stress 70 protein chaperone, microsome-associated; stress 70 protein chaperone, microsome-associated, 60kD human homolog; stress 70 protein chaperone, microsome-associated, human homolog; stress-70 protein chaperone microsome-associated 60 kDa protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21114,375,669 - 14,389,853 (-)NCBI
Rnor_6.0 Ensembl1114,144,130 - 14,160,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01114,146,515 - 14,160,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01117,802,649 - 17,816,830 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41114,521,734 - 14,535,915 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11114,521,609 - 14,535,915 (-)NCBI
Celera1114,388,645 - 14,402,826 (-)NCBICelera
Cytogenetic Map11p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
buspirone  (EXP)
butyric acid  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
celastrol  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
fenofibrate  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
gedunin  (ISO)
genistein  (ISO)
glafenine  (EXP)
glucose  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hypochlorous acid  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
mifepristone  (ISO)
nickel atom  (ISO)
nimesulide  (EXP)
paracetamol  (ISO)
perfluorononanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15489334   PMID:19199708  


Genomics

Comparative Map Data
Hspa13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21114,375,669 - 14,389,853 (-)NCBI
Rnor_6.0 Ensembl1114,144,130 - 14,160,892 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01114,146,515 - 14,160,697 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01117,802,649 - 17,816,830 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41114,521,734 - 14,535,915 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11114,521,609 - 14,535,915 (-)NCBI
Celera1114,388,645 - 14,402,826 (-)NCBICelera
Cytogenetic Map11p11NCBI
HSPA13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2114,371,115 - 14,383,484 (-)EnsemblGRCh38hg38GRCh38
GRCh382114,371,115 - 14,383,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372115,743,436 - 15,755,467 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362114,665,307 - 14,677,380 (-)NCBINCBI36hg18NCBI36
Build 342114,665,309 - 14,677,380NCBI
Celera21900,677 - 912,750 (-)NCBI
Cytogenetic Map21q11.2NCBI
HuRef211,113,800 - 1,125,871 (-)NCBIHuRef
CHM1_12115,303,921 - 15,315,993 (-)NCBICHM1_1
Hspa13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391675,552,078 - 75,564,575 (-)NCBIGRCm39mm39
GRCm39 Ensembl1675,542,319 - 75,563,992 (-)Ensembl
GRCm381675,755,190 - 75,767,276 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1675,745,431 - 75,767,104 (-)EnsemblGRCm38mm10GRCm38
MGSCv371675,755,435 - 75,767,063 (-)NCBIGRCm37mm9NCBIm37
MGSCv361675,637,874 - 75,649,458 (-)NCBImm8
Celera1675,974,819 - 75,986,466 (-)NCBICelera
Cytogenetic Map16C3.1NCBI
cM Map1643.36NCBI
Hspa13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540716,195,308 - 16,206,100 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540716,195,366 - 16,205,371 (-)NCBIChiLan1.0ChiLan1.0
HSPA13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12114,468,887 - 14,480,986 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2114,468,887 - 14,480,986 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0211,101,715 - 1,113,865 (-)NCBIMhudiblu_PPA_v0panPan3
HSPA13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13111,365,374 - 11,377,896 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3111,367,788 - 11,377,828 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3111,376,570 - 11,389,273 (-)NCBI
ROS_Cfam_1.03111,390,307 - 11,403,009 (-)NCBI
UMICH_Zoey_3.13111,363,132 - 11,375,866 (-)NCBI
UNSW_CanFamBas_1.03111,400,638 - 11,413,475 (-)NCBI
UU_Cfam_GSD_1.03111,797,157 - 11,809,886 (-)NCBI
Hspa13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497112,476,191 - 12,486,942 (-)NCBI
SpeTri2.0NW_0049365057,395,962 - 7,406,662 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPA13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13179,310,703 - 179,321,205 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113179,309,746 - 179,321,297 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213189,549,394 - 189,560,925 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSPA13
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1278,136,291 - 78,148,457 (+)NCBI
ChlSab1.1 Ensembl278,136,170 - 78,148,991 (+)Ensembl
Hspa13
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247452,841,736 - 2,851,844 (-)NCBI

Position Markers
RH142228  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21114,375,679 - 14,375,856 (+)MAPPER
Rnor_6.01114,146,526 - 14,146,702NCBIRnor6.0
Rnor_5.01117,802,660 - 17,802,836UniSTSRnor5.0
RGSC_v3.41114,521,745 - 14,521,921UniSTSRGSC3.4
Celera1114,388,656 - 14,388,832UniSTS
Cytogenetic Map11p11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11935127454351274Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11133867429Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11172720192Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)1132503169342559Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111136730644444347Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:50
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000047320
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 57 41 19 41 1 1 74 35 41 11 1
Low 11 7 10 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000081096   ⟹   ENSRNOP00000070174
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1114,146,521 - 14,160,697 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091864   ⟹   ENSRNOP00000071352
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1114,144,130 - 14,160,892 (-)Ensembl
RefSeq Acc Id: NM_019271   ⟹   NP_062144
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21114,375,669 - 14,389,853 (-)NCBI
Rnor_6.01114,146,515 - 14,160,697 (-)NCBI
Rnor_5.01117,802,649 - 17,816,830 (-)NCBI
RGSC_v3.41114,521,734 - 14,535,915 (-)RGD
Celera1114,388,645 - 14,402,826 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_062144 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB88258 (Get FASTA)   NCBI Sequence Viewer  
  AAH70954 (Get FASTA)   NCBI Sequence Viewer  
  EDM10581 (Get FASTA)   NCBI Sequence Viewer  
  EDM10582 (Get FASTA)   NCBI Sequence Viewer  
  O35162 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_062144   ⟸   NM_019271
- Peptide Label: precursor
- UniProtKB: O35162 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070174   ⟸   ENSRNOT00000081096
RefSeq Acc Id: ENSRNOP00000071352   ⟸   ENSRNOT00000091864

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698004
Promoter ID:EPDNEW_R8529
Type:multiple initiation site
Name:Hspa13_1
Description:heat shock protein family A member 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01114,160,720 - 14,160,780EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3775 AgrOrtholog
Ensembl Genes ENSRNOG00000060979 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070174 UniProtKB/Swiss-Prot
  ENSRNOP00000071352 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081096 UniProtKB/Swiss-Prot
  ENSRNOT00000091864 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7103134 IMAGE-MGC_LOAD
InterPro ATPase_NBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Heat_shock_70_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp_70_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSPA13 UniProtKB/Swiss-Prot
KEGG Report rno:29734 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91712 IMAGE-MGC_LOAD
NCBI Gene 29734 ENTREZGENE
PANTHER PTHR19375 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HSP70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hspa13 PhenoGen
PROSITE HSP70_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP70_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP70_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC230358
UniProt A0A0G2K093_RAT UniProtKB/TrEMBL
  HSP13_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q6IRE1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-05 Hspa13  heat shock protein family A (Hsp70) member 13  Hspa13  heat shock protein 70 family, member 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-06-04 Hspa13  heat shock protein 70 family, member 13  Hspa13  heat shock protein 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-29 Hspa13  heat shock protein 13  Hspa13  heat shock protein 70 family, member 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-27 Hspa13  heat shock protein 70 family, member 13  Hspa13  heat shock protein 70kDa family, member 13  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Hspa13  heat shock protein 70kDa family, member 13  Stch  stress 70 protein chaperone, microsome-associated, human homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Stch  stress 70 protein chaperone, microsome-associated, human homolog  Stch  stress 70 protein chaperone, microsome-associated  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Stch  stress 70 protein chaperone, microsome-associated  Stch  stress 70 protein chaperone, microsome-associated, 60kD human homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Stch  stress 70 protein chaperone, microsome-associated, 60kD human homolog       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains novel microsome-associated protein member of the stress70 protein chaperone family 634153
gene_process brings about cellular responses to protein processing requirements 634153
gene_protein protein has a membrane-bound microsome fraction 634153