Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of ATG3 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Atg3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATG3 mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-deoxy-D-glucose | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | Deoxyglucose affects the reaction [demycarosyl-3D-digitoxosylmithramycin SK affects the expression of ATG3 mRNA] | CTD | PMID:26079942 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of ATG3 mRNA | CTD | PMID:28970181 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of ATG3 protein | CTD | PMID:31675489 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Atg3 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ATG3 mRNA | CTD | PMID:29741722 | 4,4'-sulfonyldiphenol | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of ATG3 protein | CTD | PMID:34186270 | 4-nonylphenol | increases expression | EXP | | 6480464 | 4-nonylphenol results in increased expression of ATG3 mRNA | CTD | PMID:28041982 | 4-phenylbutyric acid | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of ATG3 protein] | CTD | PMID:35398186 | all-trans-retinoic acid | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | SPI1 protein affects the reaction [Tretinoin results in increased expression of ATG3 mRNA] | CTD | PMID:29743969 | all-trans-retinoic acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ATG3 mRNA | CTD | PMID:29743969 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ATG3 mRNA | CTD | PMID:16483693 | amphotericin B | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Amphotericin B results in decreased expression of ATG3 mRNA | CTD | PMID:20849824 | arsenite(3-) | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | arsenite results in increased expression of ATG3 mRNA | CTD | PMID:34929507 | arsenous acid | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of ATG3 mRNA | CTD | PMID:31846860 more ... | artesunate | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Artesunate results in increased expression of ATG3 mRNA | CTD | PMID:30551460 | atrazine | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] | CTD | PMID:30360616 | atrazine | decreases expression | ISO | Atg3 (Mus musculus) | 6480464 | Atrazine results in decreased expression of ATG3 mRNA | CTD | PMID:30360616 | benzo[a]pyrene | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ATG3 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATG3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ATG3 protein | CTD | PMID:31675489 | bisphenol A | decreases expression | ISO | Atg3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ATG3 mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ATG3 mRNA | CTD | PMID:27539358 | Bisphenol B | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of ATG3 protein | CTD | PMID:34186270 | butyric acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Butyric Acid results in increased expression of ATG3 protein | CTD | PMID:26784903 | cadmium sulfide | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | cadmium sulfide results in increased expression of ATG3 mRNA | CTD | PMID:27866839 | cantharidin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Cantharidin results in increased expression of ATG3 protein | CTD | PMID:35398186 | cantharidin | increases expression | EXP | | 6480464 | Cantharidin results in increased expression of ATG3 protein | CTD | PMID:35398186 | cantharidin | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | 4-phenylbutyric acid inhibits the reaction [Cantharidin results in increased expression of ATG3 protein] | CTD | PMID:35398186 | captan | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Captan results in increased expression of ATG3 mRNA | CTD | PMID:31558096 | carbon nanotube | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATG3 mRNA | CTD | PMID:20938992 | cisplatin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ATG3 protein | CTD | PMID:24817946 | cisplatin | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of ATG3 mRNA | CTD | PMID:30871063 | cisplatin | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ATG3 mRNA | CTD | PMID:20849824 | copper atom | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [Copper Sulfate results in increased abundance of Copper] which results in increased expression of ATG3 mRNA | CTD | PMID:31491480 | copper(0) | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [Copper Sulfate results in increased abundance of Copper] which results in increased expression of ATG3 mRNA | CTD | PMID:31491480 | copper(II) sulfate | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [Copper Sulfate results in increased abundance of Copper] which results in increased expression of ATG3 mRNA | CTD | PMID:31491480 | crocidolite asbestos | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in increased expression of ATG3 mRNA | CTD | PMID:19446018 | cyclophosphamide | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Cyclophosphamide results in decreased expression of ATG3 mRNA | CTD | PMID:20849824 | cyclosporin A | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ATG3 mRNA | CTD | PMID:20106945 and PMID:25562108 | cypermethrin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | cypermethrin results in increased expression of ATG3 mRNA | CTD | PMID:27704156 | decabromodiphenyl ether | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of ATG3 protein | CTD | PMID:31675489 | deguelin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | deguelin results in increased expression of ATG3 mRNA | CTD | PMID:33512557 | diarsenic trioxide | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Arsenic Trioxide results in increased expression of ATG3 mRNA | CTD | PMID:31846860 more ... | dibutyl phthalate | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of ATG3 mRNA | CTD | PMID:21266533 | dorsomorphin | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATG3 mRNA | CTD | PMID:27188386 | enniatin | decreases expression | EXP | | 6480464 | enniatins results in decreased expression of ATG3 mRNA | CTD | PMID:27163883 | enzyme inhibitor | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ATG3 protein | CTD | PMID:23301498 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of ATG3 mRNA | CTD | PMID:17920746 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of ATG3 mRNA | CTD | PMID:24136188 | fingolimod hydrochloride | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Fingolimod Hydrochloride results in increased expression of ATG3 protein | CTD | PMID:25939952 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ATG3 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | folic acid | decreases expression | ISO | Atg3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ATG3 mRNA | CTD | PMID:25629700 | folpet | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | folpet results in increased expression of ATG3 mRNA | CTD | PMID:31558096 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of ATG3 gene | CTD | PMID:22079235 | galangin | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [ATG3 mutant form co-treated with galangin] results in decreased activity of CASP3 protein more ... | CTD | PMID:25268046 | galangin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | galangin results in increased expression of ATG3 mRNA and galangin results in increased expression of ATG3 protein | CTD | PMID:25268046 | gentamycin | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Gentamicins results in decreased expression of ATG3 mRNA | CTD | PMID:20849824 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ATG3 mRNA | CTD | PMID:33387578 | glyphosate | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Glyphosate results in increased expression of ATG3 mRNA | CTD | PMID:31874349 | ivermectin | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ATG3 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATG3 mRNA | CTD | PMID:20938992 | lycopene | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] | CTD | PMID:30360616 | methidathion | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | methidathion results in increased expression of ATG3 mRNA | CTD | PMID:34813904 | nickel atom | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Nickel results in increased expression of ATG3 mRNA | CTD | PMID:25583101 | oligopeptide | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Oligopeptides analog results in increased expression of ATG3 protein | CTD | PMID:24875536 | paracetamol | affects expression | ISO | Atg3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ATG3 mRNA | CTD | PMID:17562736 | perfluorobutyric acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | perfluorobutyric acid results in increased expression of ATG3 mRNA | CTD | PMID:37806615 | perfluorooctanoic acid | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of ATG3 mRNA | CTD | PMID:26879310 | perfluorooctanoic acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ATG3 mRNA | CTD | PMID:37806615 | phenobarbital | multiple interactions | EXP | | 6480464 | Phenobarbital inhibits the reaction [Dietary Fats results in increased expression of ATG3 mRNA] | CTD | PMID:36657701 | platycodin D | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | platycodin D results in increased expression of ATG3 protein | CTD | PMID:26078792 | quercetin | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ATG3 mRNA | CTD | PMID:21632981 | resveratrol | decreases expression | ISO | ATG3 (Homo sapiens) | 6480464 | resveratrol results in decreased expression of ATG3 mRNA | CTD | PMID:23750556 | resveratrol | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | resveratrol results in increased expression of ATG3 mRNA | CTD | PMID:23750556 | rotenone | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Rotenone results in increased expression of ATG3 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATG3 mRNA | CTD | PMID:27188386 | sodium arsenite | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | [sodium arsenite co-treated with Dietary Fats] results in increased expression of ATG3 mRNA | CTD | PMID:30097599 | sodium arsenite | decreases expression | ISO | Atg3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ATG3 mRNA | CTD | PMID:30097599 | sodium dichromate | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | sodium bichromate results in increased expression of ATG3 mRNA | CTD | PMID:31558096 | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of ATG3 mRNA | CTD | PMID:24136188 | syringic acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | syringic acid results in increased expression of ATG3 protein | CTD | PMID:33548266 | T-2 toxin | increases expression | EXP | | 6480464 | T-2 Toxin results in increased expression of ATG3 protein | CTD | PMID:29870751 | T-2 toxin | multiple interactions | ISO | Atg3 (Mus musculus) | 6480464 | ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA] more ... | CTD | PMID:32240701 | T-2 toxin | increases expression | ISO | Atg3 (Mus musculus) | 6480464 | T-2 Toxin results in increased expression of ATG3 mRNA and T-2 Toxin results in increased expression of ATG3 protein | CTD | PMID:32240701 | theophylline | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Theophylline results in increased expression of ATG3 mRNA | CTD | PMID:18951874 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of ATG3 gene | CTD | PMID:27618143 | trovafloxacin | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | trovafloxacin results in increased expression of ATG3 mRNA | CTD | PMID:33609687 | trovafloxacin | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [trovafloxacin co-treated with TNF protein] results in increased expression of ATG3 mRNA | CTD | PMID:33609687 | valproic acid | affects expression | ISO | ATG3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ATG3 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ATG3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ATG3 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ATG3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATG3 mRNA | CTD | PMID:27188386 | |