Gene: Itgb5 (integrin subunit beta 5) Rattus norvegicus
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Symbol: Itgb5
Name: integrin subunit beta 5
Description: ENCODES a protein that exhibits signaling receptor binding; integrin binding (ortholog); INVOLVED IN cell-matrix adhesion (ortholog); endodermal cell differentiation (ortholog); epithelial cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; ASSOCIATED WITH juvenile rheumatoid arthritis (ortholog); thyroid gland disease (ortholog); FOUND IN cell leading edge (ortholog); cell surface (ortholog); focal adhesion (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin beta-5; integrin, beta 5; LOC498091; RGD1563276; similar to integrin beta-5
Orthologs:
Homo sapiens (human) : ITGB5 (integrin subunit beta 5)  HGNC  Alliance
Mus musculus (house mouse) : Itgb5 (integrin beta 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb5 (integrin subunit beta 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB5 (integrin subunit beta 5)
Canis lupus familiaris (dog) : ITGB5 (integrin subunit beta 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb5 (integrin subunit beta 5)
Sus scrofa (pig) : ITGB5 (integrin subunit beta 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01170,056,500 - 70,172,164 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01173,146,146 - 73,261,215 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11168,699,866 - 68,710,334 (+)NCBI
Celera1166,279,067 - 66,394,763 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itgb5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628869
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE