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Gene: Grik1 (glutamate ionotropic receptor kainate type subunit 1) Rattus norvegicus
Symbol: Grik1
Name: glutamate ionotropic receptor kainate type subunit 1
Description: Exhibits several functions, including glutamate binding activity; identical protein binding activity; and ion channel activity. Involved in ionotropic glutamate receptor signaling pathway; modulation of chemical synaptic transmission; and nervous system development. Localizes to several cellular components, including glutamatergic synapse; integral component of plasma membrane; and neuronal cell body. Used to study status epilepticus. Human ortholog(s) of this gene implicated in childhood absence epilepsy. Orthologous to human GRIK1 (glutamate ionotropic receptor kainate type subunit 1); PARTICIPATES IN long term potentiation; glutamate signaling pathway; INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GluK1; GluR-5; GluR5; glutamate receptor 5; glutamate receptor ionotropic kainate 1; glutamate receptor ionotropic, kainate 1; glutamate receptor, ionotropic kainate 1; glutamate receptor, ionotropic, kainate 1
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01127,811,954 - 28,213,940 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,811,957 - 27,971,359 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01131,426,627 - 31,828,737 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,703,874 - 28,106,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11127,703,874 - 28,106,450 (-)NCBI
Celera1126,906,345 - 27,304,585 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Grik1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2732
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.