Kalrn (kalirin, RhoGEF kinase) - Rat Genome Database

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Gene: Kalrn (kalirin, RhoGEF kinase) Rattus norvegicus
Analyze
Symbol: Kalrn
Name: kalirin, RhoGEF kinase
RGD ID: 621865
Description: Enables enzyme binding activity. Involved in several processes, including regulation of dendrite development; regulation of modification of postsynaptic actin cytoskeleton; and regulation of neurotransmitter receptor localization to postsynaptic specialization membrane. Located in neuronal cell body and perinuclear region of cytoplasm. Is active in glutamatergic synapse; postsynaptic density; and presynapse. Human ortholog(s) of this gene implicated in cerebral atherosclerosis; cerebral infarction; and coronary artery disease. Orthologous to human KALRN (kalirin RhoGEF kinase); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cyclin B1; Duo; Hapip; huntingtin-associated protein interacting protein (duo); huntingtin-associated protein-interacting protein; kalirin; P-CIP10; PAM COOH-terminal interactor protein 10; serine/threonine kinase with Dbl- and pleckstrin homology domain; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,703,345 - 80,309,210 (+)NCBIGRCr8
mRatBN7.21166,198,155 - 66,803,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,087,947 - 75,631,070 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,750,338 - 68,292,956 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,780,418 - 67,323,530 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,484,293 - 70,025,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,575,016 - 73,115,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,124,348 - 68,611,336 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,205,034 - 68,668,925 (+)NCBI
Celera1165,708,953 - 66,248,259 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bisphenol A  (EXP,ISO)
bromuconazole  (EXP)
butanal  (ISO)
C60 fullerene  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
cocaine  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
FR900359  (ISO)
genistein  (ISO)
glycidol  (EXP)
glyphosate  (EXP)
graphite  (EXP)
hydrogen peroxide  (ISO)
kainic acid  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methoxychlor  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
permethrin  (EXP)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulindac sulfide  (ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme. Alam MR, etal., J Biol Chem 1996 Nov 8;271(45):28636-40.
2. Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme. Alam MR, etal., J Biol Chem 1997 May 9;272(19):12667-75.
3. The Kalirin Gene rs9289231 Polymorphism as a Novel Predisposing Marker for Coronary Artery Disease. Boroumand M, etal., Lab Med. 2014 Fall;45(4):302-8. doi: 10.1309/LMLS813ZDPHRFLUU.
4. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
5. Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain. Colomer V, etal., Hum Mol Genet 1997 Sep;6(9):1519-25.
6. Genetic Variation of the Kalirin Gene is Associated with ICAS in the Chinese Population. Dang M, etal., J Mol Neurosci. 2018 Oct;66(2):157-162. doi: 10.1007/s12031-018-1130-2. Epub 2018 Sep 19.
7. KALRN Rare and Common Variants and Susceptibility to Ischemic Stroke in Chinese Han Population. Dang M, etal., Neuromolecular Med. 2015 Sep;17(3):241-50. doi: 10.1007/s12017-015-8352-z. Epub 2015 Apr 28.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Hayashi-Takagi A, etal., Nat Neurosci. 2010 Mar;13(3):327-32. Epub 2010 Feb 7.
10. Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking. Horne BD, etal., Ann Hum Genet. 2009 Nov;73(Pt 6):551-8. doi: 10.1111/j.1469-1809.2009.00540.x. Epub 2009 Aug 25.
11. Isoforms of kalirin, a neuronal Dbl family member, generated through use of different 5'- and 3'-ends along with an internal translational initiation site. Johnson RC, etal., J Biol Chem 2000 Jun 23;275(25):19324-33.
12. Genetic Variant of Kalirin Gene Is Associated with Ischemic Stroke in a Chinese Han Population. Li H, etal., Biomed Res Int. 2017;2017:6594271. doi: 10.1155/2017/6594271. Epub 2017 Jun 19.
13. Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. Ma XM, etal., J Neurosci 2003 Nov 19;23(33):10593-603.
14. Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms. May V, etal., J Neurosci 2002 Aug 15;22(16):6980-90.
15. Association of KALRN, ADIPOQ, and FTO gene polymorphism in type 2 diabetic patients with coronary artery disease: possible predisposing markers. Mofarrah M, etal., Coron Artery Dis. 2016 Sep;27(6):490-6. doi: 10.1097/MCA.0000000000000386.
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
18. Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome". Owczarek S, etal., Neural Plast. 2015;2015:167308. doi: 10.1155/2015/167308. Epub 2015 May 20.
19. Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action. Paskus JD, etal., Cell Rep. 2019 Dec 3;29(10):2944-2952.e5. doi: 10.1016/j.celrep.2019.10.115.
20. The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Penzes P, etal., Neuron. 2001 Jan;29(1):229-42.
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. GOA pipeline RGD automated data pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Association between Serum Kalirin Levels and the KALRN gene rs9289231 Polymorphism in Early-Onset Coronary Artery Disease. Shafiei A, etal., J Tehran Heart Cent. 2018 Apr;13(2):58-64.
26. Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. Xie Z, etal., Neuron. 2007 Nov 21;56(4):640-56.
Additional References at PubMed
PMID:9915831   PMID:10692441   PMID:10974569   PMID:12546821   PMID:14742910   PMID:15923627   PMID:16644733   PMID:18585704   PMID:18625710   PMID:18628310   PMID:19020030   PMID:19056867  
PMID:19625617   PMID:19889983   PMID:20333733   PMID:21880917   PMID:22458534   PMID:22738176   PMID:23116210   PMID:23288169   PMID:23516288   PMID:23742124   PMID:23825406   PMID:25146373  
PMID:25378388   PMID:25865668   PMID:26921771   PMID:27989699   PMID:28418645   PMID:30053369   PMID:30565792   PMID:30875016   PMID:32203420   PMID:32375403   PMID:38143048  


Genomics

Comparative Map Data
Kalrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81179,703,345 - 80,309,210 (+)NCBIGRCr8
mRatBN7.21166,198,155 - 66,803,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1175,087,947 - 75,631,070 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01167,750,338 - 68,292,956 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,780,418 - 67,323,530 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,484,293 - 70,025,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,575,016 - 73,115,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,124,348 - 68,611,336 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,205,034 - 68,668,925 (+)NCBI
Celera1165,708,953 - 66,248,259 (+)NCBICelera
Cytogenetic Map11q22NCBI
KALRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383124,033,369 - 124,726,325 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3124,033,369 - 124,726,325 (+)EnsemblGRCh38hg38GRCh38
GRCh373123,752,216 - 124,445,172 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,296,275 - 125,922,726 (+)NCBINCBI36Build 36hg18NCBI36
Celera3122,221,230 - 122,847,210 (+)NCBICelera
Cytogenetic Map3q21.1-q21.2NCBI
HuRef3121,187,838 - 121,814,322 (+)NCBIHuRef
CHM1_13123,776,558 - 124,403,021 (+)NCBICHM1_1
T2T-CHM13v2.03126,759,499 - 127,452,146 (+)NCBIT2T-CHM13v2.0
Kalrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391633,789,443 - 34,393,647 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1633,789,443 - 34,393,902 (-)EnsemblGRCm39 Ensembl
GRCm381633,969,073 - 34,573,277 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1633,969,073 - 34,573,532 (-)EnsemblGRCm38mm10GRCm38
MGSCv371633,969,159 - 34,514,113 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361633,892,682 - 34,433,795 (-)NCBIMGSCv36mm8
Celera1634,453,093 - 34,990,407 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.27NCBI
Kalrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542723,184,739 - 23,816,811 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542723,184,751 - 23,823,128 (+)NCBIChiLan1.0ChiLan1.0
KALRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,994,732 - 122,687,369 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,999,508 - 122,692,146 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03121,138,136 - 121,828,723 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13128,098,363 - 128,722,156 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3128,225,413 - 128,720,441 (+)Ensemblpanpan1.1panPan2
KALRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13327,161,403 - 27,752,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3327,161,504 - 27,746,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3327,117,706 - 27,776,818 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03327,329,328 - 27,797,773 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3327,328,803 - 27,985,259 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13327,125,464 - 27,784,937 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03327,169,910 - 27,829,241 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03327,786,940 - 28,447,934 (+)NCBIUU_Cfam_GSD_1.0
Kalrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602126,658,106 - 127,230,908 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936725572,868 - 1,139,142 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936725749,382 - 1,020,702 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KALRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113135,653,795 - 136,277,072 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213145,158,050 - 145,609,817 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KALRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12256,106,677 - 56,820,004 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2256,151,819 - 56,754,538 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041109,573,807 - 110,217,834 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kalrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624731121,122 - 752,942 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473154,934 - 756,707 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kalrn
5285 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:202
Count of miRNA genes:136
Interacting mature miRNAs:149
Transcripts:ENSRNOT00000002324, ENSRNOT00000016340, ENSRNOT00000049292
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114545932375190161Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat

Markers in Region
D11Mgh3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,422,148 - 66,422,316 (+)MAPPERmRatBN7.2
Rnor_6.01169,649,708 - 69,649,875NCBIRnor6.0
Rnor_5.01172,739,687 - 72,739,854UniSTSRnor5.0
RGSC_v3.41168,234,781 - 68,234,949RGDRGSC3.4
RGSC_v3.41168,234,782 - 68,234,949UniSTSRGSC3.4
RGSC_v3.11168,292,371 - 68,292,538RGD
Celera1165,874,140 - 65,874,287UniSTS
RH 3.4 Map11411.0UniSTS
RH 3.4 Map11411.0RGD
Cytogenetic Map11q22UniSTS
D11Arb4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,422,141 - 66,422,377 (+)MAPPERmRatBN7.2
Rnor_6.01169,649,701 - 69,649,936NCBIRnor6.0
Rnor_5.01172,739,680 - 72,739,915UniSTSRnor5.0
RGSC_v3.41168,234,774 - 68,235,010RGDRGSC3.4
RGSC_v3.41168,234,775 - 68,235,010UniSTSRGSC3.4
RGSC_v3.11168,292,364 - 68,292,599RGD
Celera1165,874,133 - 65,874,348UniSTS
RH 3.4 Map11416.8UniSTS
RH 3.4 Map11416.8RGD
RH 2.0 Map11147.1RGD
SHRSP x BN Map1129.8399RGD
Cytogenetic Map11q22UniSTS
D11Got53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,414,395 - 66,414,504 (+)MAPPERmRatBN7.2
Rnor_6.01169,641,939 - 69,642,047NCBIRnor6.0
Rnor_5.01172,731,918 - 72,732,026UniSTSRnor5.0
RGSC_v3.41168,227,012 - 68,227,121RGDRGSC3.4
RGSC_v3.41168,227,013 - 68,227,121UniSTSRGSC3.4
RGSC_v3.11168,284,602 - 68,284,710RGD
Celera1165,866,395 - 65,866,495UniSTS
RH 3.4 Map11416.9UniSTS
RH 3.4 Map11416.9RGD
RH 2.0 Map11147.0RGD
Cytogenetic Map11q22UniSTS
BE102756  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map11423.8UniSTS
Cytogenetic Map11q22UniSTS
RH137364  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,762,510 - 66,762,678 (+)MAPPERmRatBN7.2
Rnor_6.01169,990,587 - 69,990,754NCBIRnor6.0
Rnor_5.01173,080,299 - 73,080,466UniSTSRnor5.0
RGSC_v3.41168,575,790 - 68,575,957UniSTSRGSC3.4
Celera1166,213,376 - 66,213,543UniSTS
RH 3.4 Map11410.0UniSTS
Cytogenetic Map11q22UniSTS
BE110052  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,550,775 - 66,550,986 (+)MAPPERmRatBN7.2
Rnor_6.01169,778,868 - 69,779,078NCBIRnor6.0
Rnor_5.01172,868,257 - 72,868,467UniSTSRnor5.0
RGSC_v3.41168,363,209 - 68,363,419UniSTSRGSC3.4
Celera1166,001,487 - 66,001,697UniSTS
RH 3.4 Map11413.6UniSTS
Cytogenetic Map11q22UniSTS
BF396995  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,584,216 - 66,584,428 (+)MAPPERmRatBN7.2
Rnor_6.01169,812,304 - 69,812,515NCBIRnor6.0
Rnor_5.01172,901,599 - 72,901,810UniSTSRnor5.0
RGSC_v3.41168,396,645 - 68,396,856UniSTSRGSC3.4
Celera1166,034,975 - 66,035,186UniSTS
RH 3.4 Map11415.4UniSTS
Cytogenetic Map11q22UniSTS
AU046621  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01172,583,938 - 72,584,303NCBIRnor5.0
RGSC_v3.41168,082,751 - 68,083,111UniSTSRGSC3.4
Celera1165,717,382 - 65,717,746UniSTS
Cytogenetic Map11q22UniSTS
RH137626  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,797,618 - 66,797,774 (+)MAPPERmRatBN7.2
Rnor_6.01170,025,691 - 70,025,846NCBIRnor6.0
Rnor_5.01173,115,337 - 73,115,492UniSTSRnor5.0
RGSC_v3.41168,611,345 - 68,611,500UniSTSRGSC3.4
Celera1166,248,268 - 66,248,423UniSTS
Cytogenetic Map11q22UniSTS
RH138291  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,698,064 - 66,698,218 (+)MAPPERmRatBN7.2
Rnor_6.01169,926,149 - 69,926,302NCBIRnor6.0
Rnor_5.01173,015,452 - 73,015,605UniSTSRnor5.0
RGSC_v3.41168,511,288 - 68,511,441UniSTSRGSC3.4
Celera1166,148,872 - 66,149,025UniSTS
RH 3.4 Map11420.8UniSTS
Cytogenetic Map11q22UniSTS
AU049016  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21166,739,774 - 66,740,015 (+)MAPPERmRatBN7.2
mRatBN7.21166,739,924 - 66,740,015 (+)MAPPERmRatBN7.2
Rnor_6.01169,968,003 - 69,968,093NCBIRnor6.0
Rnor_6.01169,967,853 - 69,968,093NCBIRnor6.0
Rnor_5.01173,057,717 - 73,057,807UniSTSRnor5.0
Rnor_5.01173,057,567 - 73,057,807UniSTSRnor5.0
RGSC_v3.41168,552,992 - 68,553,232UniSTSRGSC3.4
RGSC_v3.41168,553,142 - 68,553,232UniSTSRGSC3.4
Celera1166,190,796 - 66,190,886UniSTS
Celera1166,190,646 - 66,190,886UniSTS
Cytogenetic Map11q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_032062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF046121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF229255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF230644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF232668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF232669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY621095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LS482391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U88157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000016340   ⟹   ENSRNOP00000016340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,198,173 - 66,628,157 (+)Ensembl
Rnor_6.0 Ensembl1169,739,384 - 69,856,241 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000049292   ⟹   ENSRNOP00000039072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,969 - 66,797,610 (+)Ensembl
Rnor_6.0 Ensembl1169,484,293 - 70,025,633 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098731   ⟹   ENSRNOP00000078050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,969 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101686   ⟹   ENSRNOP00000097769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,688,941 - 66,797,589 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112350   ⟹   ENSRNOP00000084630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,616,200 - 66,760,639 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114138   ⟹   ENSRNOP00000089775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,198,173 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117056   ⟹   ENSRNOP00000094025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,810 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118953   ⟹   ENSRNOP00000084297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,254,682 - 66,797,610 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119829   ⟹   ENSRNOP00000083298
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1166,688,941 - 66,765,434 (+)Ensembl
RefSeq Acc Id: NM_032062   ⟹   NP_114451
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,760,161 - 80,302,770 (+)NCBI
mRatBN7.21166,254,969 - 66,797,610 (+)NCBI
Rnor_6.01169,484,293 - 70,025,682 (+)NCBI
Rnor_5.01172,575,016 - 73,115,328 (+)NCBI
RGSC_v3.41168,124,348 - 68,611,336 (+)RGD
Celera1165,708,953 - 66,248,259 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088638   ⟹   XP_038944566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088639   ⟹   XP_038944567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088640   ⟹   XP_038944568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088641   ⟹   XP_038944569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,254,969 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088642   ⟹   XP_038944570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,345 - 80,309,210 (+)NCBI
mRatBN7.21166,198,520 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088643   ⟹   XP_038944571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,254,969 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088644   ⟹   XP_038944572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,797,564 (+)NCBI
RefSeq Acc Id: XM_039088645   ⟹   XP_038944573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088646   ⟹   XP_038944574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088647   ⟹   XP_038944575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,748 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088648   ⟹   XP_038944576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,814,904 - 80,309,210 (+)NCBI
mRatBN7.21166,311,425 - 66,797,602 (+)NCBI
RefSeq Acc Id: XM_039088649   ⟹   XP_038944577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,750 - 80,309,210 (+)NCBI
mRatBN7.21166,251,542 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088650   ⟹   XP_038944578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,749 - 80,309,210 (+)NCBI
mRatBN7.21166,251,541 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088651   ⟹   XP_038944579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,755 - 80,274,361 (+)NCBI
mRatBN7.21166,251,544 - 66,770,216 (+)NCBI
RefSeq Acc Id: XM_039088652   ⟹   XP_038944580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,761,497 (+)NCBI
RefSeq Acc Id: XM_039088653   ⟹   XP_038944581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,761,497 (+)NCBI
RefSeq Acc Id: XM_039088654   ⟹   XP_038944582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,756 - 80,265,803 (+)NCBI
mRatBN7.21166,251,545 - 66,760,639 (+)NCBI
RefSeq Acc Id: XM_039088655   ⟹   XP_038944583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
mRatBN7.21166,251,545 - 66,760,966 (+)NCBI
RefSeq Acc Id: XM_039088656   ⟹   XP_038944584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,816,614 - 80,266,650 (+)NCBI
mRatBN7.21166,311,425 - 66,761,474 (+)NCBI
RefSeq Acc Id: XM_039088657   ⟹   XP_038944585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,016,509 - 80,309,210 (+)NCBI
mRatBN7.21166,511,317 - 66,803,166 (+)NCBI
RefSeq Acc Id: XM_039088658   ⟹   XP_038944586
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,346 - 80,239,355 (+)NCBI
mRatBN7.21166,198,155 - 66,736,072 (+)NCBI
RefSeq Acc Id: XM_039088660   ⟹   XP_038944588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088661   ⟹   XP_038944589
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,347 - 80,134,722 (+)NCBI
mRatBN7.21166,198,156 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088662   ⟹   XP_038944590
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088663   ⟹   XP_038944591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088664   ⟹   XP_038944592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,703,347 - 80,134,722 (+)NCBI
mRatBN7.21166,198,156 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088665   ⟹   XP_038944593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,752 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088666   ⟹   XP_038944594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_039088667   ⟹   XP_038944595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,134,722 (+)NCBI
mRatBN7.21166,251,543 - 66,629,551 (+)NCBI
RefSeq Acc Id: XM_063270778   ⟹   XP_063126848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,751 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270779   ⟹   XP_063126849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270780   ⟹   XP_063126850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,758 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270781   ⟹   XP_063126851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,757 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270782   ⟹   XP_063126852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,759 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270783   ⟹   XP_063126853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81179,756,760 - 80,266,650 (+)NCBI
RefSeq Acc Id: XM_063270784   ⟹   XP_063126854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,193,785 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270785   ⟹   XP_063126855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,193,790 - 80,309,210 (+)NCBI
RefSeq Acc Id: XM_063270786   ⟹   XP_063126856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,073 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270787   ⟹   XP_063126857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,077 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270788   ⟹   XP_063126858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,078 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270789   ⟹   XP_063126859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,075 - 80,265,803 (+)NCBI
RefSeq Acc Id: XM_063270790   ⟹   XP_063126860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81180,194,076 - 80,265,803 (+)NCBI
Protein Sequences
Protein RefSeqs NP_114451 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944566 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944567 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944568 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944569 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944570 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944571 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944572 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944573 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944574 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944575 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944576 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944577 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944578 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944579 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944580 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944581 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944582 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944583 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944584 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944585 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944586 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944588 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944589 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944590 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944591 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944592 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944593 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944594 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944595 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126848 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126849 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126850 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126851 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126852 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126853 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126854 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126855 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126856 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126857 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126858 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126859 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126860 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB66366 (Get FASTA)   NCBI Sequence Viewer  
  AAB66367 (Get FASTA)   NCBI Sequence Viewer  
  AAC03057 (Get FASTA)   NCBI Sequence Viewer  
  AAC15790 (Get FASTA)   NCBI Sequence Viewer  
  AAF66014 (Get FASTA)   NCBI Sequence Viewer  
  AAF66018 (Get FASTA)   NCBI Sequence Viewer  
  AAF66019 (Get FASTA)   NCBI Sequence Viewer  
  AAF69144 (Get FASTA)   NCBI Sequence Viewer  
  AAT39517 (Get FASTA)   NCBI Sequence Viewer  
  EDM11342 (Get FASTA)   NCBI Sequence Viewer  
  EDM11343 (Get FASTA)   NCBI Sequence Viewer  
  EDM11344 (Get FASTA)   NCBI Sequence Viewer  
  EDM11345 (Get FASTA)   NCBI Sequence Viewer  
  EDM11346 (Get FASTA)   NCBI Sequence Viewer  
  EDM11347 (Get FASTA)   NCBI Sequence Viewer  
  EDM11348 (Get FASTA)   NCBI Sequence Viewer  
  EDM11349 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016340.8
  ENSRNOP00000039072.5
  ENSRNOP00000078050.1
  ENSRNOP00000083298.1
  ENSRNOP00000084297.1
  ENSRNOP00000084630.1
  ENSRNOP00000089775.1
  ENSRNOP00000094025.1
  ENSRNOP00000097769.1
GenBank Protein P97924 (Get FASTA)   NCBI Sequence Viewer  
  SPT35768 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_114451   ⟸   NM_032062
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016340   ⟸   ENSRNOT00000016340
Ensembl Acc Id: ENSRNOP00000039072   ⟸   ENSRNOT00000049292
RefSeq Acc Id: XP_038944586   ⟸   XM_039088658
- Peptide Label: isoform X27
- UniProtKB: A6IRJ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944589   ⟸   XM_039088661
- Peptide Label: isoform X29
- UniProtKB: A0A8L2Q7U3 (UniProtKB/TrEMBL),   A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944592   ⟸   XM_039088664
- Peptide Label: isoform X32
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944570   ⟸   XM_039088642
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ACF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944566   ⟸   XM_039088638
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944574   ⟸   XM_039088646
- Peptide Label: isoform X9
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944567   ⟸   XM_039088639
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944568   ⟸   XM_039088640
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944578   ⟸   XM_039088650
- Peptide Label: isoform X14
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944573   ⟸   XM_039088645
- Peptide Label: isoform X8
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944575   ⟸   XM_039088647
- Peptide Label: isoform X10
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944572   ⟸   XM_039088644
- Peptide Label: isoform X7
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944577   ⟸   XM_039088649
- Peptide Label: isoform X12
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944588   ⟸   XM_039088660
- Peptide Label: isoform X28
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944591   ⟸   XM_039088663
- Peptide Label: isoform X31
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944594   ⟸   XM_039088666
- Peptide Label: isoform X34
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944595   ⟸   XM_039088667
- Peptide Label: isoform X35
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944590   ⟸   XM_039088662
- Peptide Label: isoform X30
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944593   ⟸   XM_039088665
- Peptide Label: isoform X33
- UniProtKB: A6IRJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944579   ⟸   XM_039088651
- Peptide Label: isoform X15
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944581   ⟸   XM_039088653
- Peptide Label: isoform X17
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944580   ⟸   XM_039088652
- Peptide Label: isoform X16
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944583   ⟸   XM_039088655
- Peptide Label: isoform X22
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944582   ⟸   XM_039088654
- Peptide Label: isoform X21
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944569   ⟸   XM_039088641
- Peptide Label: isoform X4
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944571   ⟸   XM_039088643
- Peptide Label: isoform X6
- UniProtKB: A0A8I6GKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944576   ⟸   XM_039088648
- Peptide Label: isoform X11
- UniProtKB: Q9JIH3 (UniProtKB/Swiss-Prot),   Q9JIG0 (UniProtKB/Swiss-Prot),   Q9JIF2 (UniProtKB/Swiss-Prot),   Q9JIF1 (UniProtKB/Swiss-Prot),   Q6IV51 (UniProtKB/Swiss-Prot),   P97924 (UniProtKB/Swiss-Prot),   O70135 (UniProtKB/Swiss-Prot),   A0A2X0SFF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944584   ⟸   XM_039088656
- Peptide Label: isoform X23
- UniProtKB: A6IRJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944585   ⟸   XM_039088657
- Peptide Label: isoform X26
- UniProtKB: A6IRI9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084297   ⟸   ENSRNOT00000118953
Ensembl Acc Id: ENSRNOP00000078050   ⟸   ENSRNOT00000098731
Ensembl Acc Id: ENSRNOP00000094025   ⟸   ENSRNOT00000117056
Ensembl Acc Id: ENSRNOP00000084630   ⟸   ENSRNOT00000112350
Ensembl Acc Id: ENSRNOP00000097769   ⟸   ENSRNOT00000101686
Ensembl Acc Id: ENSRNOP00000083298   ⟸   ENSRNOT00000119829
Ensembl Acc Id: ENSRNOP00000089775   ⟸   ENSRNOT00000114138
RefSeq Acc Id: XP_063126848   ⟸   XM_063270778
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A0Z4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126849   ⟸   XM_063270779
- Peptide Label: isoform X18
RefSeq Acc Id: XP_063126851   ⟸   XM_063270781
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063126850   ⟸   XM_063270780
- Peptide Label: isoform X19
RefSeq Acc Id: XP_063126852   ⟸   XM_063270782
- Peptide Label: isoform X24
RefSeq Acc Id: XP_063126853   ⟸   XM_063270783
- Peptide Label: isoform X25
RefSeq Acc Id: XP_063126854   ⟸   XM_063270784
- Peptide Label: isoform X36
RefSeq Acc Id: XP_063126855   ⟸   XM_063270785
- Peptide Label: isoform X37
RefSeq Acc Id: XP_063126856   ⟸   XM_063270786
- Peptide Label: isoform X38
RefSeq Acc Id: XP_063126859   ⟸   XM_063270789
- Peptide Label: isoform X41
RefSeq Acc Id: XP_063126860   ⟸   XM_063270790
- Peptide Label: isoform X42
RefSeq Acc Id: XP_063126857   ⟸   XM_063270787
- Peptide Label: isoform X39
RefSeq Acc Id: XP_063126858   ⟸   XM_063270788
- Peptide Label: isoform X40
Protein Domains
CRAL-TRIO   DH   Fibronectin type-III   Ig-like   Ig-like C2-type   PH   Protein kinase   SH3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621865 AgrOrtholog
BioCyc Gene G2FUF-21148 BioCyc
Ensembl Genes ENSRNOG00000001706 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016340.8 UniProtKB/TrEMBL
  ENSRNOT00000049292.7 UniProtKB/TrEMBL
  ENSRNOT00000098731.1 UniProtKB/TrEMBL
  ENSRNOT00000101686.1 UniProtKB/TrEMBL
  ENSRNOT00000112350.1 UniProtKB/TrEMBL
  ENSRNOT00000114138.1 UniProtKB/TrEMBL
  ENSRNOT00000117056.1 UniProtKB/TrEMBL
  ENSRNOT00000118953.1 UniProtKB/TrEMBL
  ENSRNOT00000119829.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.525.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CRAL-TRIO_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kalirin/TRIO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kalirin_TRIO_PH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kalirin_TRIO_SH3_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF_Guanine_NuclExch_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84009 UniProtKB/Swiss-Prot
NCBI Gene 84009 ENTREZGENE
PANTHER KALIRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LD43457P UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B-RELATED UniProtKB/TrEMBL
  RHO GUANINE EXCHANGE FACTOR-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CRAL_TRIO_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-RhoG_link UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kalrn PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001706 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Spectrin repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52087 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2X0SFF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y1V9_RAT UniProtKB/TrEMBL
  A0A8I5ZVT3_RAT UniProtKB/TrEMBL
  A0A8I6A0J4_RAT UniProtKB/TrEMBL
  A0A8I6A0Z4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ACF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AUW1_RAT UniProtKB/TrEMBL
  A0A8I6GKY9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q7U3 ENTREZGENE, UniProtKB/TrEMBL
  A6IRI9 ENTREZGENE, UniProtKB/TrEMBL
  A6IRJ0 ENTREZGENE, UniProtKB/TrEMBL
  A6IRJ2_RAT UniProtKB/TrEMBL
  A6IRJ3 ENTREZGENE, UniProtKB/TrEMBL
  A6IRJ4 ENTREZGENE, UniProtKB/TrEMBL
  A6IRJ6_RAT UniProtKB/TrEMBL
  F1LZV1_RAT UniProtKB/TrEMBL
  KALRN_RAT UniProtKB/Swiss-Prot
  O70135 ENTREZGENE
  P97924 ENTREZGENE
  Q6IV51 ENTREZGENE
  Q9JIF1 ENTREZGENE
  Q9JIF2 ENTREZGENE
  Q9JIG0 ENTREZGENE
  Q9JIH3 ENTREZGENE
UniProt Secondary O70135 UniProtKB/Swiss-Prot
  Q6IV51 UniProtKB/Swiss-Prot
  Q9JIF1 UniProtKB/Swiss-Prot
  Q9JIF2 UniProtKB/Swiss-Prot
  Q9JIG0 UniProtKB/Swiss-Prot
  Q9JIH3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-03-14 Kalrn  kalirin, RhoGEF kinase  Hapip  huntingtin-associated protein interacting protein (duo)  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2002-08-07 Hapip  huntingtin-associated protein interacting protein (duo)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains dual Rho GTPase guanine nucleotide exchange factor (GEF) domains that interact with Rac1 and RhoA 628431
gene_expression expressed mainly in the nervous system 628431
gene_physical_interaction binds to the cytoplasmic domain of peptidylglycine alpha-amidating monooxygenase (PAM), a membrane protein mediating neuropeptide biosynthesis 628431
gene_process participates in regulation of neuronal fiber extension and pathfinding during development 628431
gene_process initiates new axons and axonal outgrowth via RhoG-mediated mechanisms 628431