Krtap11-1 (keratin associated protein 11-1) - Rat Genome Database

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Gene: Krtap11-1 (keratin associated protein 11-1) Rattus norvegicus
Analyze
Symbol: Krtap11-1
Name: keratin associated protein 11-1
RGD ID: 2323257
Description: Predicted to enable structural molecule activity. Predicted to be located in cytosol and keratin filament. Orthologous to human KRTAP11-1 (keratin associated protein 11-1); INTERACTS WITH Cuprizon; aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: keratin associated protein 11-1-like; keratin-associated protein 11-1; LOC100359886
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,296,147 - 42,297,151 (-)NCBIGRCr8
mRatBN7.21128,809,940 - 28,810,944 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,810,341 - 28,810,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1137,489,356 - 37,490,360 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01130,189,382 - 30,190,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01129,358,981 - 29,359,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,709,809 - 29,711,328 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,710,298 - 29,710,849 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01133,331,876 - 33,332,729 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,368,418 - 29,368,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1128,501,631 - 28,503,150 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Krtap11-1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,296,147 - 42,297,151 (-)NCBIGRCr8
mRatBN7.21128,809,940 - 28,810,944 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,810,341 - 28,810,892 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1137,489,356 - 37,490,360 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01130,189,382 - 30,190,386 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01129,358,981 - 29,359,985 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,709,809 - 29,711,328 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,710,298 - 29,710,849 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01133,331,876 - 33,332,729 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,368,418 - 29,368,969 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1128,501,631 - 28,503,150 (-)NCBICelera
Cytogenetic Map11q11NCBI
KRTAP11-1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,880,644 - 30,881,580 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,880,644 - 30,881,580 (-)EnsemblGRCh38hg38GRCh38
GRCh372132,252,963 - 32,253,899 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362131,174,834 - 31,175,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 342131,174,836 - 31,175,745NCBI
Celera2117,435,937 - 17,436,848 (-)NCBICelera
Cytogenetic Map21q22.11NCBI
HuRef2117,662,496 - 17,663,407 (-)NCBIHuRef
CHM1_12131,814,848 - 31,815,759 (-)NCBICHM1_1
T2T-CHM13v2.02129,248,387 - 29,249,323 (-)NCBIT2T-CHM13v2.0
Krtap11-1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391689,367,064 - 89,368,071 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1689,367,064 - 89,368,071 (-)EnsemblGRCm39 Ensembl
GRCm381689,570,176 - 89,571,183 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1689,570,176 - 89,571,183 (-)EnsemblGRCm38mm10GRCm38
MGSCv371689,570,421 - 89,571,428 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1689,772,122 - 89,773,129 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1651.42NCBI
LOC102012159
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540730,616,942 - 30,617,415 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540730,616,573 - 30,617,451 (-)NCBIChiLan1.0ChiLan1.0
LOC100996196
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22226,988,044 - 26,993,784 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12121,847,064 - 21,852,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02117,242,331 - 17,243,396 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12130,626,543 - 30,627,448 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2130,626,932 - 30,627,423 (-)Ensemblpanpan1.1panPan2
KRTAP11-1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13125,879,638 - 25,920,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3125,870,035 - 25,911,009 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03125,994,781 - 26,035,743 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3125,995,174 - 25,995,635 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13125,942,242 - 25,983,159 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03125,953,816 - 25,994,795 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03126,421,892 - 26,462,790 (-)NCBIUU_Cfam_GSD_1.0
LOC101966313
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497126,455,508 - 26,456,454 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650011,011,460 - 11,011,951 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650011,011,456 - 11,011,960 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRTAP11-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13194,506,052 - 194,506,525 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113194,505,660 - 194,506,576 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213204,904,394 - 204,905,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRTAP11-1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1261,238,451 - 61,241,444 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl261,240,513 - 61,240,971 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660713,791,275 - 3,792,206 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101710042
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474519,371,264 - 19,371,707 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474519,371,264 - 19,371,707 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:89
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000029345
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system appendage
High
Medium
Low 2 2 2
Below cutoff 2 1 1 1 1 1 14 6 13 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029345   ⟹   ENSRNOP00000037310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1128,810,341 - 28,810,892 (-)Ensembl
Rnor_6.0 Ensembl1129,710,298 - 29,710,849 (-)Ensembl
RefSeq Acc Id: NM_001399002   ⟹   NP_001385931
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81142,296,147 - 42,297,151 (-)NCBI
mRatBN7.21128,809,940 - 28,810,944 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001385931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000037310
  ENSRNOP00000037310.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000037310   ⟸   ENSRNOT00000029345
RefSeq Acc Id: NP_001385931   ⟸   NM_001399002
- UniProtKB: D3ZX50 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZX50-F1-model_v2 AlphaFold D3ZX50 1-183 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698049
Promoter ID:EPDNEW_R8567
Type:single initiation site
Name:Krtap11-1_1
Description:keratin associated protein 11-1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01129,710,901 - 29,710,961EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2323257 AgrOrtholog
BioCyc Gene G2FUF-21972 BioCyc
Ensembl Genes ENSRNOG00000027478 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029345 ENTREZGENE
  ENSRNOT00000029345.3 UniProtKB/TrEMBL
InterPro Keratin_matx UniProtKB/TrEMBL
  PMG UniProtKB/TrEMBL
NCBI Gene 100359886 ENTREZGENE
PANTHER KERATIN ASSOCIATED PROTEIN 3-3-RELATED UniProtKB/TrEMBL
  KERATIN-ASSOCIATED PROTEIN 11-1 UniProtKB/TrEMBL
Pfam PMG UniProtKB/TrEMBL
PhenoGen Krtap11-1 PhenoGen
RatGTEx ENSRNOG00000027478 RatGTEx
UniProt D3ZX50 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-26 Krtap11-1  keratin associated protein 11-1  LOC100359886  keratin associated protein 11-1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-06 LOC100359886  keratin associated protein 11-1-like      Symbol and Name status set to provisional 70820 PROVISIONAL