Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tmprss2 (transmembrane serine protease 2) Rattus norvegicus
Symbol: Tmprss2
Name: transmembrane serine protease 2
RGD ID: 620766
Description: Predicted to have scavenger receptor activity and serine-type endopeptidase activity. Predicted to be involved in positive regulation of viral entry into host cell and protein autoprocessing. Predicted to localize to plasma membrane. Orthologous to human TMPRSS2 (transmembrane serine protease 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: transmembrane protease serine 2; transmembrane protease, serine 2
Homo sapiens (human) : TMPRSS2 (transmembrane serine protease 2)  HGNC  Alliance
Mus musculus (house mouse) : Tmprss2 (transmembrane protease, serine 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmprss2 (transmembrane serine protease 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TMPRSS2 (transmembrane serine protease 2)
Canis lupus familiaris (dog) : TMPRSS2 (transmembrane serine protease 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmprss2 (transmembrane serine protease 2)
Sus scrofa (pig) : TMPRSS2 (transmembrane serine protease 2)
Chlorocebus sabaeus (African green monkey) : TMPRSS2 (transmembrane serine protease 2)
Heterocephalus glaber (naked mole-rat) : Tmprss2 (transmembrane serine protease 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01138,063,914 - 38,103,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,574,415 - 41,613,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,577,051 - 37,617,258 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11137,634,640 - 37,674,847 (-)NCBI
Celera1136,819,034 - 36,858,331 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tmprss2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620766
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.