Tmprss2 (transmembrane serine protease 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tmprss2 (transmembrane serine protease 2) Rattus norvegicus
Analyze
Symbol: Tmprss2
Name: transmembrane serine protease 2
RGD ID: 620766
Description: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in protein autoprocessing. Predicted to be located in nucleoplasm and plasma membrane. Orthologous to human TMPRSS2 (transmembrane serine protease 2); PARTICIPATES IN influenza A pathway; .
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: transmembrane protease serine 2; transmembrane protease, serine 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,403,707 - 50,443,224 (-)NCBIGRCr8
mRatBN7.21136,934,306 - 36,973,779 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,934,306 - 36,973,715 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,634,788 - 45,674,172 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,306,168 - 38,345,554 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,466,096 - 37,505,480 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,063,914 - 38,103,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,574,415 - 41,613,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,577,051 - 37,617,258 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,634,640 - 37,674,847 (-)NCBI
Celera1136,819,034 - 36,858,331 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection. Iwata-Yoshikawa N, etal., J Virol. 2019 Mar 5;93(6). pii: JVI.01815-18. doi: 10.1128/JVI.01815-18. Print 2019 Mar 15.
3. The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma. Lucas JM, etal., J Pathol. 2008 Jun;215(2):118-25.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Expression of transmembrane serine protease TMPRSS2 in mouse and human tissues. Vaarala MH, etal., J Pathol 2001 Jan;193(1):134-40.
Additional References at PubMed
PMID:19056867   PMID:19199708   PMID:21068237   PMID:23376485   PMID:23533145   PMID:24227843   PMID:28064310   PMID:32404436   PMID:32940922   PMID:33660945   PMID:34684358   PMID:35000261  


Genomics

Comparative Map Data
Tmprss2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,403,707 - 50,443,224 (-)NCBIGRCr8
mRatBN7.21136,934,306 - 36,973,779 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,934,306 - 36,973,715 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,634,788 - 45,674,172 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,306,168 - 38,345,554 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,466,096 - 37,505,480 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,063,914 - 38,103,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,574,415 - 41,613,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,577,051 - 37,617,258 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,634,640 - 37,674,847 (-)NCBI
Celera1136,819,034 - 36,858,331 (-)NCBICelera
Cytogenetic Map11q12NCBI
TMPRSS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382141,529,791 - 41,531,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2141,464,300 - 41,531,116 (-)EnsemblGRCh38hg38GRCh38
GRCh372142,836,232 - 42,880,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,758,351 - 41,801,948 (-)NCBINCBI36Build 36hg18NCBI36
Build 342141,758,350 - 41,801,948NCBI
Celera2128,034,659 - 28,078,450 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2128,305,352 - 28,349,365 (-)NCBIHuRef
CHM1_12142,397,265 - 42,440,908 (-)NCBICHM1_1
Tmprss2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,365,882 - 97,460,741 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1697,365,882 - 97,412,395 (-)EnsemblGRCm39 Ensembl
GRCm381697,564,682 - 97,659,541 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,564,682 - 97,611,195 (-)EnsemblGRCm38mm10GRCm38
MGSCv371697,786,289 - 97,832,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361697,719,598 - 97,766,111 (-)NCBIMGSCv36mm8
Celera1698,625,511 - 98,672,561 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.53NCBI
Tmprss2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540740,957,122 - 40,976,644 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540740,958,562 - 40,985,415 (-)NCBIChiLan1.0ChiLan1.0
TMPRSS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22237,547,072 - 37,580,116 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12132,401,351 - 32,434,400 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02127,800,466 - 27,843,395 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,128,358 - 41,170,924 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,131,515 - 41,161,088 (-)Ensemblpanpan1.1panPan2
Tmprss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,245,118 - 35,277,589 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365002,199,835 - 2,222,174 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365002,199,877 - 2,222,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMPRSS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,372,881 - 85,413,717 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,372,117 - 85,412,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605413,228,416 - 13,267,943 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmprss2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474528,573,095 - 28,595,426 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474528,565,515 - 28,593,102 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmprss2
198 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:583
Count of miRNA genes:271
Interacting mature miRNAs:344
Transcripts:ENSRNOT00000002713, ENSRNOT00000066413
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat

Markers in Region
RH134371  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21136,934,551 - 36,934,732 (+)MAPPERmRatBN7.2
Rnor_6.01138,064,160 - 38,064,340NCBIRnor6.0
Rnor_5.01141,574,661 - 41,574,841UniSTSRnor5.0
RGSC_v3.41137,577,297 - 37,577,477UniSTSRGSC3.4
Celera1136,819,280 - 36,819,460UniSTS
RH 3.4 Map11280.2UniSTS
Cytogenetic Map11q12UniSTS
UniSTS:495843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21136,937,074 - 36,937,125 (+)MAPPERmRatBN7.2
Rnor_6.01138,066,683 - 38,066,733NCBIRnor6.0
Rnor_5.01141,577,184 - 41,577,234UniSTSRnor5.0
RGSC_v3.41137,579,820 - 37,579,870UniSTSRGSC3.4
Celera1136,821,802 - 36,821,852UniSTS
Cytogenetic Map11q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 9 11
Low 4 39 27 19 27 14 24
Below cutoff 15 18 14 14 8 10 46 5 8

Sequence


RefSeq Acc Id: ENSRNOT00000002713   ⟹   ENSRNOP00000002713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1136,934,314 - 36,973,715 (-)Ensembl
Rnor_6.0 Ensembl1138,066,594 - 38,088,753 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000066413   ⟹   ENSRNOP00000062828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1136,934,306 - 36,973,715 (-)Ensembl
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)Ensembl
RefSeq Acc Id: NM_130424   ⟹   NP_569108
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,403,707 - 50,443,114 (-)NCBI
mRatBN7.21136,934,306 - 36,973,715 (-)NCBI
Rnor_6.01138,063,914 - 38,103,321 (-)NCBI
Rnor_5.01141,574,415 - 41,613,911 (-)NCBI
RGSC_v3.41137,577,051 - 37,617,258 (-)RGD
Celera1136,819,034 - 36,858,331 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768547   ⟹   XP_008766769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,403,718 - 50,443,224 (-)NCBI
mRatBN7.21136,936,463 - 36,973,779 (-)NCBI
Rnor_6.01138,066,298 - 38,103,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768548   ⟹   XP_008766770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,403,718 - 50,443,159 (-)NCBI
mRatBN7.21136,936,463 - 36,973,761 (-)NCBI
Rnor_6.01138,066,298 - 38,103,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270250   ⟹   XP_063126320
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,403,718 - 50,443,093 (-)NCBI
RefSeq Acc Id: NP_569108   ⟸   NM_130424
- UniProtKB: Q6P7D7 (UniProtKB/TrEMBL),   F7EQ71 (UniProtKB/TrEMBL),   Q920K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766769   ⟸   XM_008768547
- Peptide Label: isoform X1
- UniProtKB: Q920K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766770   ⟸   XM_008768548
- Peptide Label: isoform X1
- UniProtKB: Q920K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002713   ⟸   ENSRNOT00000002713
RefSeq Acc Id: ENSRNOP00000062828   ⟸   ENSRNOT00000066413
RefSeq Acc Id: XP_063126320   ⟸   XM_063270250
- Peptide Label: isoform X2
Protein Domains
Peptidase S1   SRCR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P7D7-F1-model_v2 AlphaFold Q6P7D7 1-490 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698094
Promoter ID:EPDNEW_R8619
Type:single initiation site
Name:Tmprss2_1
Description:transmembrane protease, serine 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01138,103,305 - 38,103,365EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620766 AgrOrtholog
BioCyc Gene G2FUF-21682 BioCyc
Ensembl Genes ENSRNOG00000001976 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002713.4 UniProtKB/TrEMBL
  ENSRNOT00000066413 ENTREZGENE
  ENSRNOT00000066413.4 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  3.10.250.10 UniProtKB/TrEMBL
  4.10.400.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598010 IMAGE-MGC_LOAD
InterPro LDL_receptor-like_sf UniProtKB/TrEMBL
  LDLR_class-A_CS UniProtKB/TrEMBL
  LDrepeatLR_classA_rpt UniProtKB/TrEMBL
  Pept_cys/ser_Trypsin-like UniProtKB/TrEMBL
  Peptidase_S1/S6_AS UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1_S6 UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/TrEMBL
  Srcr_rcpt UniProtKB/TrEMBL
  Srcr_rcpt-rel UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report rno:156435 UniProtKB/TrEMBL
MGC_CLONE MGC:72325 IMAGE-MGC_LOAD
NCBI Gene 156435 ENTREZGENE
PANTHER ACROSIN UniProtKB/TrEMBL
  ACROSIN-RELATED UniProtKB/TrEMBL
  CUB DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEASE SERINE UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEASE SERINE 2 UniProtKB/TrEMBL
Pfam Ldl_recept_a UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PhenoGen Tmprss2 PhenoGen
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE LDLRA_1 UniProtKB/TrEMBL
  LDLRA_2 UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001976 RatGTEx
SMART LDLa UniProtKB/TrEMBL
  SM00202 UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP LDL_rcpt_classA_cys-rich UniProtKB/TrEMBL
  Pept_Ser_Cys UniProtKB/TrEMBL
  Srcr_receptor UniProtKB/TrEMBL
UniProt A6IQG7_RAT UniProtKB/TrEMBL
  A6IQG8_RAT UniProtKB/TrEMBL
  A6IQH0_RAT UniProtKB/TrEMBL
  A6IQH1_RAT UniProtKB/TrEMBL
  F1M6J6_RAT UniProtKB/TrEMBL
  F7EQ71 ENTREZGENE, UniProtKB/TrEMBL
  Q6P7D7 ENTREZGENE, UniProtKB/TrEMBL
  Q920K3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-26 Tmprss2  transmembrane serine protease 2  Tmprss2  transmembrane protease, serine 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tmprss2  transmembrane protease, serine 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tmprss2  transmembrane protease, serine 2      Symbol and Name status set to provisional 70820 PROVISIONAL