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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | RGD:1320470 | 6480464 | ethylene dichloride results in decreased expression of CHODL mRNA | CTD | PMID:28960355 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of CHODL mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1320470 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CHODL mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CHODL mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CHODL mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1320470 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of CHODL mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1320470 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of CHODL mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | RGD:1320469 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased methylation of CHODL gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1320469 | 6480464 | [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of CHODL gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CHODL mRNA | CTD | PMID:24780913 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of CHODL mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of CHODL mRNA | CTD | PMID:23630614 | arsenous acid | decreases expression | ISO | RGD:1320469 | 6480464 | Arsenic Trioxide results in decreased expression of CHODL mRNA | CTD | PMID:26705709 | belinostat | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | belinostat | increases expression | ISO | RGD:1320469 | 6480464 | belinostat results in increased expression of CHODL mRNA | CTD | PMID:26272509 | benzo[a]pyrene | affects methylation | ISO | RGD:1320469 | 6480464 | Benzo(a)pyrene affects the methylation of CHODL promoter | CTD | PMID:27901495 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of CHODL mRNA | CTD | PMID:26496021 | bisphenol A | increases methylation | ISO | RGD:1320469 | 6480464 | bisphenol A results in increased methylation of CHODL gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | RGD:1320469 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CHODL gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CHODL mRNA | CTD | PMID:33296240 | bisphenol A | increases expression | ISO | RGD:1320470 | 6480464 | bisphenol A results in increased expression of CHODL mRNA | CTD | PMID:30951980 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CHODL mRNA | CTD | PMID:25181051 | bisphenol F | increases expression | ISO | RGD:1320470 | 6480464 | bisphenol F results in increased expression of CHODL mRNA | CTD | PMID:30951980 | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of CHODL promoter | CTD | PMID:22457795 | CGP 52608 | multiple interactions | ISO | RGD:1320469 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CHODL gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | RGD:1320470 | 6480464 | Chlorpyrifos results in increased expression of CHODL mRNA | CTD | PMID:32715474 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of CHODL mRNA | CTD | PMID:26577399 | diarsenic trioxide | decreases expression | ISO | RGD:1320469 | 6480464 | Arsenic Trioxide results in decreased expression of CHODL mRNA | CTD | PMID:26705709 | dichloroacetic acid | decreases expression | ISO | RGD:1320470 | 6480464 | Dichloroacetic Acid results in decreased expression of CHODL mRNA | CTD | PMID:28962523 | dorsomorphin | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | RGD:1320469 | 6480464 | Doxorubicin results in increased expression of CHODL mRNA | CTD | PMID:30031762 | entinostat | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | RGD:1320469 | 6480464 | entinostat results in increased expression of CHODL mRNA | CTD | PMID:26272509 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of CHODL mRNA | CTD | PMID:31881178 | folic acid | increases expression | ISO | RGD:1320470 | 6480464 | Folic Acid results in increased expression of CHODL mRNA | CTD | PMID:25629700 | folic acid | decreases expression | ISO | RGD:1320469 | 6480464 | Folic Acid results in decreased expression of CHODL mRNA | CTD | PMID:21867686 | fulvestrant | multiple interactions | ISO | RGD:1320469 | 6480464 | [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of CHODL gene, [bisphenol A co-treated with Fulvestrant] results in increased methylation of CHODL gene | CTD | PMID:31601247 | genistein | decreases expression | ISO | RGD:1320470 | 6480464 | Genistein results in decreased expression of CHODL mRNA | CTD | PMID:32186404 | lidocaine | decreases expression | EXP | | 6480464 | Lidocaine results in decreased expression of CHODL mRNA | CTD | PMID:35283115 | mercury dibromide | increases expression | ISO | RGD:1320469 | 6480464 | mercuric bromide results in increased expression of CHODL mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | nickel atom | decreases expression | ISO | RGD:1320469 | 6480464 | Nickel results in decreased expression of CHODL mRNA | CTD | PMID:24768652 | p-chloromercuribenzoic acid | increases expression | ISO | RGD:1320469 | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of CHODL mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | panobinostat | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:1320469 | 6480464 | panobinostat results in increased expression of CHODL mRNA | CTD | PMID:26272509 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CHODL mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of CHODL mRNA | CTD | PMID:32680482 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of CHODL mRNA | CTD | PMID:25905778 | SB 431542 | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | decreases expression | ISO | RGD:1320470 | 6480464 | Silver results in decreased expression of CHODL mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1320470 | 6480464 | Silver results in decreased expression of CHODL mRNA | CTD | PMID:27131904 | testosterone | increases expression | ISO | RGD:1320470 | 6480464 | Testosterone deficiency results in increased expression of CHODL mRNA | CTD | PMID:33848595 | testosterone undecanoate | decreases expression | ISO | RGD:1320469 | 6480464 | testosterone undecanoate results in decreased expression of CHODL mRNA | CTD | PMID:19074003 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of CHODL mRNA | CTD | PMID:23411599 | trichostatin A | decreases expression | ISO | RGD:1320469 | 6480464 | trichostatin A results in decreased expression of CHODL mRNA | CTD | PMID:26705709 | valproic acid | affects expression | ISO | RGD:1320470 | 6480464 | Valproic Acid affects the expression of CHODL mRNA | CTD | PMID:17292431 | valproic acid | decreases expression | ISO | RGD:1320469 | 6480464 | Valproic Acid results in decreased expression of CHODL mRNA | CTD | PMID:23179753 | valproic acid | increases expression | ISO | RGD:1320470 | 6480464 | Valproic Acid results in increased expression of CHODL mRNA | CTD | PMID:24896083 | valproic acid | increases expression | ISO | RGD:1320469 | 6480464 | Valproic Acid results in increased expression of CHODL mRNA | CTD | PMID:24383497 more ... | valproic acid | multiple interactions | ISO | RGD:1320469 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA | CTD | PMID:27188386 | XL147 | multiple interactions | ISO | RGD:1320470 | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHODL mRNA | CTD | PMID:27935865 | |