Zbtb21 (zinc finger and BTB domain containing 21) - Rat Genome Database

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Gene: Zbtb21 (zinc finger and BTB domain containing 21) Rattus norvegicus
Analyze
Symbol: Zbtb21
Name: zinc finger and BTB domain containing 21
RGD ID: 1310841
Description: Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; POZ domain binding activity; and sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZBTB21 (zinc finger and BTB domain containing 21); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC304056; Zfp295; zinc finger and BTB domain-containing protein 21; zinc finger protein 295; Znf295
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21137,311,860 - 37,327,040 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1138,442,742 - 38,457,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01138,442,716 - 38,457,411 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01141,952,579 - 41,967,272 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,960,562 - 37,973,333 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11138,017,645 - 38,030,920 (-)NCBI
Celera1137,198,647 - 37,211,419 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

References

Additional References at PubMed
PMID:15629158   PMID:21029866  


Genomics

Comparative Map Data
Zbtb21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21137,311,860 - 37,327,040 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1138,442,742 - 38,457,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01138,442,716 - 38,457,411 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01141,952,579 - 41,967,272 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,960,562 - 37,973,333 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11138,017,645 - 38,030,920 (-)NCBI
Celera1137,198,647 - 37,211,419 (-)NCBICelera
Cytogenetic Map11q12NCBI
ZBTB21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,986,831 - 42,010,387 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,986,831 - 42,010,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372143,406,940 - 43,430,469 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,280,009 - 42,303,565 (-)NCBINCBI36hg18NCBI36
Build 342142,280,008 - 42,303,519NCBI
Celera2128,554,479 - 28,578,036 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,824,422 - 28,847,984 (-)NCBIHuRef
CHM1_12142,967,781 - 42,991,342 (-)NCBICHM1_1
Zbtb21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,746,993 - 97,763,850 (-)NCBIGRCm39mm39
GRCm39 Ensembl1697,744,557 - 97,763,822 (-)Ensembl
GRCm381697,945,795 - 97,962,627 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,943,357 - 97,962,622 (-)EnsemblGRCm38mm10GRCm38
MGSCv371698,168,599 - 98,183,786 (-)NCBIGRCm37mm9NCBIm37
MGSCv361698,103,856 - 98,117,095 (-)NCBImm8
Celera1698,999,188 - 99,014,381 (-)NCBICelera
Cytogenetic Map16C4NCBI
Zbtb21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,584,146 - 39,599,381 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540739,583,998 - 39,599,381 (+)NCBIChiLan1.0ChiLan1.0
ZBTB21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12141,633,208 - 41,656,714 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,633,208 - 41,656,714 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02128,310,177 - 28,333,713 (-)NCBIMhudiblu_PPA_v0panPan3
ZBTB21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13136,378,200 - 36,394,894 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3136,379,566 - 36,394,911 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,527,041 - 35,546,651 (-)NCBI
ROS_Cfam_1.03135,892,390 - 35,912,002 (-)NCBI
UMICH_Zoey_3.13135,785,769 - 35,793,200 (-)NCBI
UNSW_CanFamBas_1.03135,765,471 - 35,785,062 (-)NCBI
UU_Cfam_GSD_1.03136,260,200 - 36,279,825 (-)NCBI
Zbtb21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,619,647 - 35,640,036 (-)NCBI
SpeTri2.0NW_0049365001,827,785 - 1,848,176 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZBTB21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113205,345,675 - 205,365,151 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213215,671,579 - 215,698,593 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZBTB21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,871,708 - 85,894,964 (-)NCBI
ChlSab1.1 Ensembl285,875,805 - 85,879,005 (-)Ensembl
Vero_WHO_p1.0NW_02366605413,731,642 - 13,754,899 (-)NCBI
Zbtb21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474528,304,795 - 28,329,497 (+)NCBI

Position Markers
UniSTS:234008  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,312,186 - 37,312,389 (+)MAPPERmRatBN7.2
Rnor_6.01138,442,563 - 38,442,764NCBIRnor6.0
Rnor_5.01141,952,426 - 41,952,627UniSTSRnor5.0
Celera1137,196,610 - 37,196,812UniSTS
Cytogenetic Map11q12UniSTS
BF403709  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,313,466 - 37,313,618 (+)MAPPERmRatBN7.2
Rnor_6.01138,443,842 - 38,443,993NCBIRnor6.0
Rnor_5.01141,953,705 - 41,953,856UniSTSRnor5.0
Celera1137,197,890 - 37,198,041UniSTS
RH 3.4 Map11266.5UniSTS
Cytogenetic Map11q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11172720192Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)1132503169342559Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11935127454351274Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111136730644444347Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111632197346583360Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111947517979734728Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)112194422966944229Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)112194422966944229Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)112204314944444112Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112540112970401129Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112572003870720038Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112572003870720038Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112572003870720038Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112831466586994795Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113043533963186373Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)113043533986714631Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113215552082443118Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113590063480900634Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:243
Count of miRNA genes:163
Interacting mature miRNAs:182
Transcripts:ENSRNOT00000041177
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 19 4 15 4 74 22 35 11
Low 3 39 38 37 4 37 8 11 13 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000041177   ⟹   ENSRNOP00000049174
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1138,442,742 - 38,457,373 (-)Ensembl
RefSeq Acc Id: NM_001107105   ⟹   NP_001100575
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,314,224 - 37,326,996 (-)NCBI
Rnor_6.01138,444,603 - 38,457,375 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
RGSC_v3.41137,960,562 - 37,973,333 (-)RGD
Celera1137,198,647 - 37,211,419 (-)RGD
Sequence:
RefSeq Acc Id: XM_006248166   ⟹   XP_006248228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,311,860 - 37,327,032 (-)NCBI
Rnor_6.01138,442,716 - 38,457,410 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248167   ⟹   XP_006248229
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,326,781 (-)NCBI
Rnor_6.01138,442,716 - 38,457,160 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248169   ⟹   XP_006248231
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,040 (-)NCBI
Rnor_6.01138,442,716 - 38,457,410 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248172   ⟹   XP_006248234
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,034 (-)NCBI
Rnor_6.01138,442,716 - 38,457,411 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248174   ⟹   XP_006248236
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,037 (-)NCBI
Rnor_6.01138,442,716 - 38,457,410 (-)NCBI
Rnor_5.01141,952,579 - 41,967,272 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088400   ⟹   XP_038944328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,033 (-)NCBI
RefSeq Acc Id: XM_039088401   ⟹   XP_038944329
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,033 (-)NCBI
RefSeq Acc Id: XM_039088403   ⟹   XP_038944331
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,030 (-)NCBI
RefSeq Acc Id: XM_039088404   ⟹   XP_038944332
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,034 (-)NCBI
RefSeq Acc Id: XM_039088405   ⟹   XP_038944333
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,034 (-)NCBI
RefSeq Acc Id: XM_039088406   ⟹   XP_038944334
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21137,312,337 - 37,327,029 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100575   ⟸   NM_001107105
- Sequence:
RefSeq Acc Id: XP_006248236   ⟸   XM_006248174
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006248231   ⟸   XM_006248169
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006248234   ⟸   XM_006248172
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006248228   ⟸   XM_006248166
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006248229   ⟸   XM_006248167
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000049174   ⟸   ENSRNOT00000041177
RefSeq Acc Id: XP_038944333   ⟸   XM_039088405
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944332   ⟸   XM_039088404
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944329   ⟸   XM_039088401
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944328   ⟸   XM_039088400
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944331   ⟸   XM_039088403
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944334   ⟸   XM_039088406
- Peptide Label: isoform X4
Protein Domains
BTB   C2H2-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698097
Promoter ID:EPDNEW_R8622
Type:multiple initiation site
Name:Zbtb21_1
Description:zinc finger and BTB domain containing 21
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01138,457,367 - 38,457,427EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310841 AgrOrtholog
Ensembl Genes ENSRNOG00000001623 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000049174 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041177 UniProtKB/TrEMBL
Gene3D-CATH 3.30.710.10 UniProtKB/TrEMBL
InterPro BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_6 UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
NCBI Gene 304056 ENTREZGENE
Pfam BTB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf_C2H2_6 UniProtKB/TrEMBL
PhenoGen Zbtb21 PhenoGen
PROSITE BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt D3ZVF2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-28 Zbtb21  zinc finger and BTB domain containing 21  Zfp295  zinc finger protein 295  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-19 Zfp295  zinc finger protein 295  Znf295  zinc finger protein 295  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Znf295  zinc finger protein 295  Zfp295  zinc finger protein 295   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Zfp295  zinc finger protein 295   Zfp295_predicted  zinc finger protein 295 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Zfp295_predicted  zinc finger protein 295 (predicted)      Symbol and Name status set to approved 70820 APPROVED