Bw121 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw121 (Body weight QTL 121) Rattus norvegicus

Symbol: Bw121
Name: Body weight QTL 121
RGD ID: 634341
Previously known as: Dmo10; Niddm51; Non-insulin dependent diabetes mellitus QTL 51
Trait: abdominal fat pad mass   (VT:1000711)    
Measurement Type: abdominal fat pad weight   (CMO:0000088)    
LOD Score: 3.56
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2111 - 21,836,709RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01122,043,149 - 44,444,112RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01125,682,771 - 47,637,212RGDRnor5.0
RGSC_v3.41122,214,205 - 43,156,819RGDRGSC3.4
RGSC_v3.11122,214,205 - 43,214,409RGD
Cross Type: backcross
Strains Crossed: BN OLETF 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
obesity  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN  (IEA)
OLETF  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of "OLETF," a rat model for non-insulin-dependent diabetes mellitus: quantitative trait locus analysis of (OLETF x BN) x OLETF. Watanabe TK, etal., Genomics 1999 Jun 15;58(3):233-9.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
41216714LOC1200930615.8S ribosomal RNA116296363115Rat
1584979Arl13bADP-ribosylation factor like GTPase 13B11150100217103Rat
1597703Stx19syntaxin 1911172855178053Rat
620971Pros1protein S11230597311288Rat
1584978Slc22a7-ps1solute carrier family 22 (organic anion transporter), member 7, pseudogene 111351938353606Rat
41064937LOC120095789U2 spliceosomal RNA11445023445186Rat
6494940Npm1-ps21nucleophosmin 1, pseudogene 211110765391077949Rat
41141637LOC120095801U4 spliceosomal RNA1111382101138385Rat
68389Epha3Eph receptor A31111384851474102Rat
41323621LOC120095722U7 small nuclear RNA1115517401551802Rat
41065123LOC120095723U7 small nuclear RNA1115518841551945Rat
1562102Csnka2ipcasein kinase 2 subunit alpha' interacting protein1121275532253399Rat
41113800LOC120095814U6 spliceosomal RNA1121603382160441Rat
1586142Atp5mg-ps6ATP synthase membrane subunit g, pseudogene 61124405312440945Rat
1359320C11h3orf38similar to human chromosome 3 open reading frame 381124839832488631Rat
1308321Zfp654zinc finger protein 6541125008922565552Rat
1308129Cggbp1CGG triplet repeat binding protein 11125656292572869Rat
1584835Polr2e-ps1RNA polymerase II, I and III subunit E, pseudogene 11125738802574980Rat
71083Htr1f5-hydroxytryptamine receptor 1F1126427512644150Rat
41063307LOC120095588uncharacterized LOC1200955881127737902827981Rat
41287359LOC120095746small nucleolar RNA SNORA171128038892804021Rat
41157583LOC120095754small nucleolar RNA SNORA171128893362889466Rat
2320754Gmnn-ps1geminin, pseudogene 11129255712926288Rat
3367Pou1f1POU class 1 homeobox 11133168183334804Rat
1306781Chmp2bcharged multivesicular body protein 2B1133374783364015Rat
1583675Hdac1-ps4Histone deacetylase 1, pseudogene 41134373263444652Rat
1597045Septin7-ps4septin 7, pseudogene 41134527663454294Rat
1561853Kmt5al3lysine methyltransferase 5A like 31134785653482255Rat
1560030Vgll3vestigial-like family member 31136429933692590Rat
41345038LOC120095589uncharacterized LOC1200955891136607693665940Rat
11383083Vdac1l1voltage-dependent anion channel 1 like 11140199074039409Rat
41074576LOC120095711U6 spliceosomal RNA1140718304071934Rat
6493479Cbx2-ps1chromobox 2, pseudogene 11140985984100120Rat
1598077Snrpc-ps5small nuclear ribonucleoprotein polypeptide C, pseudogene 51145404964541074Rat
1305678Cadm2cell adhesion molecule 21145483675525420Rat
41254584Eif4e-ps7eukaryotic translation initiation factor 4E, pseudogene 71153401415466490Rat
1595502Haus8l2HAUS augmin-like complex, subunit 8 like 21156284325630535Rat
2319897Rsrc1-ps2arginine and serine rich coiled-coil 1, pseudogene 21156599975661719Rat
41049956LOC120095556uncharacterized LOC1200955561162614886269975Rat
2319758Mycbp-ps2Myc binding protein, pseudogene 21164744806474806Rat
41035149LOC120095765small nucleolar RNA SNORA171165191786519307Rat
1586140Eef1akmt4-ps2EEF1A lysine methyltransferase 4, pseudogene 21167975916798891Rat
41293460LOC120095740small nucleolar RNA SNORA481168186586818801Rat
1596982Chac2-ps2ChaC glutathione specific gamma-glutamylcyclotransferase 2, pseudogene 21175941927594873Rat
2319543C2h4orf46-ps1similar to human chromosome 4 open reading frame 46, pseudogene 11178315157832373Rat
41201721Tra2a-ps2transformer 2 alpha, pseudogene 21180743708113622Rat
1583717Arl2-ps2ADP-ribosylation factor-like 2, pseudogene 21183670188368003Rat
41370750LOC120095779small nucleolar RNA U131185147618514863Rat
1586206Poglut2-ps1protein O-glucosyltransferase 2, pseudogene 11185488328550826Rat
1586207Set-ps11Set nuclear proto-oncogene, pseudogene 111185775928578429Rat
41053307LOC120095794U2 spliceosomal RNA1186682168668292Rat
2319158Eif4e-ps10eukaryotic translation initiation factor 4E, pseudogene 101186997538700439Rat
1309968Gbe11,4-alpha-glucan branching enzyme 11187348069000226Rat
41332035LOC120095590uncharacterized LOC1200955901188701068876944Rat
7669742LOC102549549uncharacterized LOC1025495491188899268905080Rat
41100346Snord22small nucleolar RNA, C/D box 221190977999097923Rat
7708718LOC102549956uncharacterized LOC1025499561191186379123382Rat
7527339LOC102550021uncharacterized LOC1025500211192152169229868Rat
1592954Chmp6-ps1charged multivesicular body protein 6, pseudogene 11197696019770333Rat
40983549LOC120095811U6 spliceosomal RNA1198037999803905Rat
61941Robo1roundabout guidance receptor 1111058086311621675Rat
11406618LOC108352379uncharacterized LOC108352379111106235411076277Rat
7696444LOC102551469uncharacterized LOC102551469111109946211136678Rat
41174631Trnav-aac31transfer RNA valine (anticodon AAC) 31111162468911624770Rat
41281293LOC120095557uncharacterized LOC120095557111165004211661186Rat
41394409LOC120095755small nucleolar RNA SNORA17111175600511756134Rat
41140540LOC120095742small nucleolar RNA SNORA48111183929611839427Rat
620167Robo2roundabout guidance receptor 2111252894914096726Rat
41205137LOC120095537uncharacterized LOC120095537111310651913110886Rat
41303579LOC120095760small nucleolar RNA SNORA17111322574413225871Rat
40981328Trnaa-agc31transfer RNA alanine (anticodon AGC) 31111355288213552953Rat
1589452Tent5b-ps1terminal nucleotidyltransferase 5B, pseudogene 1111372510613728086Rat
1310162Lipilipase I111418932314228992Rat
40969584LOC120095819U6 spliceosomal RNA111419558714195692Rat
1305195Rbm11RNA binding motif protein 11111423485114244092Rat
2319676Snrpe-ps3small nuclear ribonucleoprotein polypeptide E, pseudogene 3111436301514363571Rat
41327136LOC120095809U6 spliceosomal RNA111437012814370234Rat
3775Hspa13heat shock protein family A (Hsp70) member 13111437566914389853Rat
620926Samsn1SAM domain, SH3 domain and nuclear localization signals, 1111448452314534900Rat
41044926LOC120095752small nucleolar RNA SNORA17111475623914756370Rat
40982247LOC120095592uncharacterized LOC120095592111478952014811653Rat
11381419LOC108352292uncharacterized LOC108352292111481178414830208Rat
1311850Nrip1nuclear receptor interacting protein 1111489584314979490Rat
40959210LOC120095593uncharacterized LOC120095593111499880415011347Rat
40937056Rpl7-ps9ribosomal protein L7, pseudogene 9111535176315354240Rat
7613925LOC102556241uncharacterized LOC102556241111537164215380095Rat
7690081LOC102548078uncharacterized LOC102548078111554318415560750Rat
40997737LOC120095594uncharacterized LOC120095594111559600015602092Rat
1309003Usp25ubiquitin specific peptidase 25111560365415711356Rat
9119122LOC103693508uncharacterized LOC103693508111587174916295079Rat
41187853LOC120095539uncharacterized LOC120095539111606394616069167Rat
2325580Mir99amicroRNA 99a111620044316200523Rat
2325435Mirlet7c1microRNA let-7c-1111620116316201256Rat
4888572Mir3588microRNA 3588111624561116245716Rat
2325575Mir125b2microRNA 125b-2111624562016245707Rat
1586139Sord-ps2sorbitol dehydrogenase, pseudogene 2111639227316394420Rat
11369037LOC108352294uncharacterized LOC108352294111641274716425621Rat
41319938LOC120095805U6 spliceosomal RNA111665509016655196Rat
7521170LOC102546782uncharacterized LOC102546782111682631516831065Rat
40966767LOC120095757small nucleolar RNA SNORA17111691977616919914Rat
41087675LOC120095595uncharacterized LOC120095595111693245316939866Rat
619794CxadrCXADR, Ig-like cell adhesion molecule111698286417030078Rat
2226Btg3BTG anti-proliferation factor 3111703015617046069Rat
41011570LOC120095596uncharacterized LOC120095596111710390017113835Rat
1563888C11h21orf91similar to human chromosome 21 open reading frame 91111722912917262307Rat
40952789LOC120095597uncharacterized LOC120095597111742449717510872Rat
1597043Hspa8-ps31heat shock protein family A (Hsp70) member 8, pseudogene 31111746669117468736Rat
1309885Chodlchondrolectin111765413717676450Rat
1311046Tmprss15transmembrane serine protease 15111767774117802255Rat
1585829Rpl27l3ribosomal protein L27 like 3111797005117970433Rat
1333570Or5b129-ps1olfactory receptor family 5 subfamily B member 129, pseudogene 1111801405118014958Rat
41156026LOC12009558440S ribosomal protein S18-like111847231118473770Rat
9135017LOC10369351040S ribosomal protein S6 pseudogene111874827418748918Rat
41256742LOC120095558uncharacterized LOC120095558111876089718767970Rat
41129591LOC120095753small nucleolar RNA SNORA17111887893618879060Rat
41203619LOC120095598uncharacterized LOC120095598111887958818880497Rat
41115113LOC120095718U6 spliceosomal RNA111957838019578477Rat
1597984Pcbp2-ps8poly(rC) binding protein 2, pseudogene 8111969395819697409Rat
1303131Ncam2neural cell adhesion molecule 2112010497420592168Rat
6499722Tmem258-ps5transmembrane protein 258, pseudogene 5112060280420603028Rat
1586138Pes1-ps1pescadillo ribosomal biogenesis factor 1, pseudogene 1112153064721532896Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33899D11Mit4102112183661521836709Ratregion
34130D11Mgh6100111897620818976310Ratregion
35989D11Rat29145111342715713427302Ratregion
35989D11Rat29145111342715713427540Ratregion
37574D11Rat521611164028516403014Ratregion
35565D11Rat20143111647204716472185Ratregion
37070D11Rat28246111304993113050172Ratregion
35581D11Rat80167111085332610853485Ratregion
35633D11Rat311501182000228200174Ratregion
39962D11Rat862481140699944070242Ratregion
38678D11Rat40240111580806315808309Ratregion
38678D11Rat40240111580806315808402Ratregion
40260D11Rat871541117320361732189Ratregion
39440D11Rat77116111897199818972110Ratregion
39504D11Rat882451110419311042176Ratregion
41242D11Rat79156111352863213528786Ratregion
42942D11Rat116126111671706616717194Ratregion
42943D11Rat113248111325183513252084Ratregion
42944D11Rat112143111589081915890978Ratregion
42945D11Rat100214111818514118185343Ratregion
41734D11Rat101245111283104612831293Ratregion
44893D11Got13188111800153518001723Ratregion
44913D11Got10150111313823913138389Ratregion
44914D11Got12185111087870410878889Ratregion
44915D11Got9136111276913512769271Ratregion
44916D11Got11203111099601010996213Ratregion
44917D11Got81721193681549368325Ratregion
44918D11Got71161173814977381610Ratregion
44919D11Got52361150941275094363Ratregion
44920D11Got41481144231344423284Ratregion
44921D11Got11841150941665094350Ratregion
59990D11Got21571144231344423293Ratregion
59992D11Got32461142593624259608Ratregion
66635D11Mco7130111337177013371898Ratregion
1632029D11Got113142111187749111877630Ratregion
1633624D11Got101209111417408814174297Ratregion
1627743D11Got100199111483252614832721Ratregion
1632854D11Wox141411133065233306664Ratregion
1633500D11Got1252051125616862561891Ratregion
1640128D11Got140120111842970218429826Ratregion
1635049D11Wox181521133276873327839Ratregion
1635630D11Mco82471147287034728950Ratregion
1637691D11Got1282681180355358035803Ratregion
1634394D11Got113130111480159814801728Ratregion
5035585Epha31431111409491141092Ratregion
5025986RH130465181111767608617676267Ratregion
5026264RH1315471901124826732482863Ratregion
5028761RH142228177111437567914375856Ratregion
5031530AU048024204111296558612965787Ratregion
5035016Chodl361111766523017665591Ratregion
5035026Nrip1250111490108414901334Ratregion
5032447AI464149123111604709116047214Ratregion
5032837RH1366712151133386693338884Ratregion
5027509AW53635489111723652917236618Ratregion
5033103RH137609237112059165220591889Ratregion
5033205RH137970184111345999313460177Ratregion
5028039MHAa75g1.seq154111655658416556738Ratregion
5033637RH139555211111255554712555758Ratregion
5028348RH71142184111253272012532904Ratregion
5031075BE109239150111722952117229671Ratregion
5056181RH14423012111172117172238Ratregion
5054181RH143077114111723374917233863Ratregion
5055383RH1437701011133639103364011Ratregion
5058744BF3870171811149079604908141Ratregion
5058114BF386615176111112316211123338Ratregion
5058126BF3866551751145696594569834Ratregion
5058132BF386668175111145090111451076Ratregion
5056795RH144585164111467507014675234Ratregion
5059100BF3874971501154741215474271Ratregion
5053547RH142712100111302989513029995Ratregion
5053625RH142757122111372718913727311Ratregion
5050950RH134352200111437338014373580Ratregion
5054519RH1432711391125665052566645Ratregion
5049630RH133591195111489594814896143Ratregion
5040188RH128140180111161980611619986Ratregion
5043684RH130167208112049557820495786Ratregion
5041450RH12886318311310057310240Ratregion
5073898RH137702216111702030917020525Ratregion
5074100RH1378211221149582864958408Ratregion
5076608RH139274162111722922517229373Ratregion
5074890RH138277164111580943615809600Ratregion
5079496RH14103120211310976311178Ratregion
5077378RH139722217111253168812531905Ratregion
5078084RH14013420211310572310774Ratregion
5072866RH1370992151125724742572689Ratregion
5073272RH137340216111372782613728043Ratregion
5071842RH135316192111726120117261393Ratregion
5063356BF404162220111252905112529271Ratregion
5066608AU048257130112026089620261026Ratregion
5066646AU04823413511291305291440Ratregion
5067574AU047663123111842970318429826Ratregion
5068192AU047293117111683106616831183Ratregion
5068392AU047174219112089351520893734Ratregion
5068652AU047016173111796733917967499Ratregion
5068920AU046841210111748877117488981Ratregion
5070326AF05306279111489923514899314Ratregion
5061974AW527929176111424386714244043Ratregion
5062868BE113128150111597199115972141Ratregion
5064520BI302245216111539530215395518Ratregion
5064528BI302296154111497724014977394Ratregion
5066528AU048303219111747327317473492Ratregion
5087227AW530763155111724575517245910Ratregion
5089923AU049444257111588393015884187Ratregion
5083169BF390904205111351359013513795Ratregion
5088243AU0484521741146620184662192Ratregion
5088365AU0485252331199345259934760Ratregion
5089635AU049272234111280028812800522Ratregion
5090275AU049654151111701481817014969Ratregion
5090325AU049684219111609781716098037Ratregion
5082953BF390471191111135335011353541Ratregion
5505620UniSTS:48624813761125049982506374Ratregion
5506109UniSTS:498373671111617121161779Ratregion
5500069UniSTS:23654601175936857593949Ratregion
5501705NCAM2726112058681920587545Ratregion
5502583RH125452811125664332566514Ratregion
Position Markers

Flank 1: (D11Mgh5)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01144,444,112 - 44,444,347NCBI
Rnor_5.01147,637,212 - 47,637,447UniSTS
RGSC_v3.41143,156,819 - 43,157,054RGD
RGSC_v3.41143,156,820 - 43,157,054UniSTS
RGSC_v3.11143,214,409 - 43,214,643RGD
Celera1142,134,750 - 42,134,984UniSTS
RH 3.4 Map11311.1UniSTS
RH 3.4 Map11311.1RGD
RH 2.0 Map11309.5RGD
SHRSP x BN Map1113.8499RGD
Cytogenetic Map11 RGD
Flank 2: (D11Mit4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21121,836,615 - 21,836,709 (+)MAPPER
Rnor_6.01122,043,056 - 22,043,149NCBI
Rnor_5.01125,682,678 - 25,682,771UniSTS
RGSC_v3.41122,214,111 - 22,214,205RGD
RGSC_v3.41122,214,112 - 22,214,205UniSTS
RGSC_v3.11122,214,112 - 22,214,205RGD
Celera1121,717,308 - 21,717,401UniSTS
RH 3.4 Map5689.6UniSTS
RH 3.4 Map5689.6RGD
Cytogenetic Map11q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111283104625121472Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111897620824697116Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)11121836709Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Niddm51


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-21 Bw121  Body weight QTL 121  Niddm51  Non-insulin dependent diabetes mellitus QTL 51  Name updated 68913 APPROVED
2013-03-21 Bw121  Body weight QTL 121  Niddm51  Non-insulin dependent diabetes mellitus QTL 51  Symbol updated 68687 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_cross_type backcross  
qtl_general involved in fat and body weight regulation 619678
qtl_statistics_details QTL is also significant for body weight (LOD = 3.54) 619678