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Gene: Heph (hephaestin) Rattus norvegicus
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Symbol: Heph
Name: hephaestin
RGD ID: 71060
Description: Predicted to have copper ion binding activity; ferrous iron binding activity; and ferroxidase activity. Predicted to be involved in erythrocyte differentiation; iron ion homeostasis; and iron ion transport. Localizes to perinuclear region of cytoplasm and plasma membrane. Orthologous to human HEPH (hephaestin); PARTICIPATES IN iron efflux pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : HEPH (hephaestin)  HGNC  Alliance
Mus musculus (house mouse) : Heph (hephaestin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Heph (hephaestin)
Pan paniscus (bonobo/pygmy chimpanzee) : HEPH (hephaestin)
Canis lupus familiaris (dog) : HEPH (hephaestin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Heph (hephaestin)
Sus scrofa (pig) : HEPH (hephaestin)
Chlorocebus sabaeus (African green monkey) : HEPH (hephaestin)
Heterocephalus glaber (naked mole-rat) : Heph (hephaestin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X65,377,313 - 65,658,479 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX65,563,122 - 65,658,516 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X66,388,085 - 66,488,433 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X84,033,540 - 84,138,728 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X84,106,831 - 84,212,018 (+)NCBI
CeleraX61,712,172 - 61,814,411 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Heph
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71060
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.