1,1-dichloroethene increases expression ISO RGD:1551918 6480464 vinylidene chloride results in increased expression of TPX2 mRNA CTD PMID:26682919 1,2-dichloroethane decreases expression ISO RGD:1551918 6480464 ethylene dichloride results in decreased expression of TPX2 mRNA CTD PMID:28189721 , PMID:28960355 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of TPX2 mRNA CTD PMID:30723492 17beta-estradiol multiple interactions ISO RGD:1551918 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of TPX2 mRNA] CTD PMID:25210133 17beta-estradiol increases expression ISO RGD:1323589 6480464 Estradiol results in increased expression of TPX2 mRNA CTD PMID:19167446 17beta-estradiol increases expression ISO RGD:1551918 6480464 Estradiol results in increased expression of TPX2 mRNA CTD PMID:25210133 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:1323589 6480464 Metribolone results in increased expression of TPX2 mRNA CTD PMID:17010196 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1551918 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1551918 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1551918 6480464 AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TPX2 mRNA] CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of TPX2 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of TPX2 mRNA CTD PMID:32109520 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1551918 6480464 Tetrachlorodibenzodioxin affects the expression of TPX2 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1551918 6480464 Tetrachlorodibenzodioxin results in decreased expression of TPX2 mRNA CTD PMID:15034205 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:1323589 6480464 2 more ... CTD PMID:19031421 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1323589 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TPX2 mRNA CTD PMID:28628672 3-methylcholanthrene increases expression ISO RGD:1551918 6480464 Methylcholanthrene results in increased expression of TPX2 mRNA CTD PMID:20713471 4,4'-sulfonyldiphenol increases expression ISO RGD:1323589 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of TPX2 mRNA CTD PMID:27685785 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TPX2 mRNA CTD PMID:24780913 acetamide increases expression EXP 6480464 acetamide results in increased expression of TPX2 mRNA CTD PMID:31881176 aflatoxin B1 affects expression ISO RGD:1323589 6480464 Aflatoxin B1 affects the expression of TPX2 protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of TPX2 mRNA CTD PMID:23630614 aflatoxin B1 decreases expression ISO RGD:1551918 6480464 Aflatoxin B1 results in decreased expression of TPX2 mRNA CTD PMID:19770486 all-trans-retinoic acid decreases expression ISO RGD:1323589 6480464 Tretinoin results in decreased expression of TPX2 mRNA CTD PMID:16249480 , PMID:33167477 antimycin A increases expression ISO RGD:1323589 6480464 Antimycin A results in increased expression of TPX2 mRNA CTD PMID:33512557 antirheumatic drug decreases expression ISO RGD:1323589 6480464 Antirheumatic Agents results in decreased expression of TPX2 mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO RGD:1323589 6480464 aristolochic acid I results in decreased expression of TPX2 mRNA CTD PMID:33212167 arsenite(3-) decreases expression ISO RGD:1551918 6480464 arsenite results in decreased expression of TPX2 mRNA CTD PMID:18929588 arsenite(3-) multiple interactions ISO RGD:1323589 6480464 arsenite inhibits the reaction [G3BP1 protein binds to TPX2 mRNA] CTD PMID:32406909 azathioprine decreases expression ISO RGD:1323589 6480464 Azathioprine results in decreased expression of TPX2 mRNA CTD PMID:22623647 azoxystrobin increases expression ISO RGD:1323589 6480464 azoxystrobin results in increased expression of TPX2 mRNA CTD PMID:33512557 belinostat decreases expression ISO RGD:1323589 6480464 belinostat results in decreased expression of TPX2 mRNA CTD PMID:19606018 benzo[a]pyrene decreases expression ISO RGD:1551918 6480464 Benzo(a)pyrene results in decreased expression of TPX2 mRNA CTD PMID:15034205 benzo[a]pyrene increases expression ISO RGD:1551918 6480464 Benzo(a)pyrene results in increased expression of TPX2 mRNA CTD PMID:32417428 benzo[a]pyrene multiple interactions ISO RGD:1551918 6480464 AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of TPX2 mRNA] CTD PMID:15034205 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1323589 6480464 7 more ... CTD PMID:19150397 , PMID:20382639 benzo[b]fluoranthene increases expression ISO RGD:1551918 6480464 benzo(b)fluoranthene results in increased expression of TPX2 mRNA CTD PMID:26377693 bicalutamide decreases expression ISO RGD:1323589 6480464 bicalutamide results in decreased expression of TPX2 mRNA CTD PMID:15638997 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1323589 6480464 Mustard Gas results in decreased expression of TPX2 mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1323589 6480464 Diethylhexyl Phthalate results in increased expression of TPX2 protein CTD PMID:31163220 bisphenol A decreases expression ISO RGD:1551918 6480464 bisphenol A results in decreased expression of TPX2 mRNA CTD PMID:17706920 bisphenol A decreases expression ISO RGD:1323589 6480464 bisphenol A results in decreased expression of TPX2 mRNA CTD PMID:29275510 bisphenol A affects expression ISO RGD:1323589 6480464 bisphenol A affects the expression of TPX2 mRNA CTD PMID:30903817 bisphenol A affects localization ISO RGD:1323589 6480464 bisphenol A affects the localization of TPX2 protein CTD PMID:30980863 bisphenol A multiple interactions ISO RGD:1323589 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TPX2 mRNA CTD PMID:28628672 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of TPX2 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TPX2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1551918 6480464 LHB protein affects the reaction [bisphenol A results in decreased expression of TPX2 mRNA] CTD PMID:17706920 buta-1,3-diene increases expression ISO RGD:1551918 6480464 1, 3-butadiene results in increased expression of TPX2 mRNA CTD PMID:29038090 cadmium atom decreases expression ISO RGD:1323589 6480464 Cadmium results in decreased expression of TPX2 mRNA CTD PMID:21120746 cadmium atom increases expression ISO RGD:1323589 6480464 Cadmium results in increased expression of TPX2 mRNA CTD PMID:19031421 caffeine decreases phosphorylation ISO RGD:1323589 6480464 Caffeine results in decreased phosphorylation of TPX2 protein CTD PMID:35688186 calcitriol decreases expression ISO RGD:1323589 6480464 Calcitriol results in decreased expression of TPX2 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1323589 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TPX2 mRNA CTD PMID:21592394 carbon nanotube affects expression ISO RGD:1551918 6480464 Nanotubes, Carbon affects the expression of TPX2 mRNA CTD PMID:25554681 carbon nanotube increases expression ISO RGD:1551918 6480464 Nanotubes, Carbon analog results in increased expression of TPX2 mRNA CTD PMID:25554681 choline multiple interactions ISO RGD:1551918 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TPX2 mRNA CTD PMID:20938992 cisplatin decreases expression ISO RGD:1551918 6480464 Cisplatin results in decreased expression of TPX2 mRNA CTD PMID:25270620 cisplatin decreases expression ISO RGD:1323589 6480464 Cisplatin results in decreased expression of TPX2 mRNA CTD PMID:27594783 cobalt dichloride decreases expression ISO RGD:1323589 6480464 cobaltous chloride results in decreased expression of TPX2 mRNA CTD PMID:19320972 , PMID:19376846 copper atom multiple interactions ISO RGD:1323589 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TPX2 mRNA CTD PMID:20971185 copper atom increases expression EXP 6480464 Copper results in increased expression of TPX2 mRNA CTD PMID:30556269 copper(0) multiple interactions ISO RGD:1323589 6480464 [NSC 689534 binds to Copper] which results in decreased expression of TPX2 mRNA CTD PMID:20971185 copper(0) increases expression EXP 6480464 Copper results in increased expression of TPX2 mRNA CTD PMID:30556269 copper(II) sulfate decreases expression ISO RGD:1323589 6480464 Copper Sulfate results in decreased expression of TPX2 mRNA CTD PMID:19549813 coumarin decreases phosphorylation ISO RGD:1323589 6480464 coumarin results in decreased phosphorylation of TPX2 protein CTD PMID:35688186 coumestrol increases expression ISO RGD:1323589 6480464 Coumestrol results in increased expression of TPX2 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO RGD:1323589 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 CU-O LINKAGE decreases expression ISO RGD:1323589 6480464 cupric oxide results in decreased expression of TPX2 mRNA CTD PMID:22077320 cyclosporin A decreases expression ISO RGD:1323589 6480464 Cyclosporine results in decreased expression of TPX2 mRNA CTD PMID:20106945 more ... deguelin increases expression ISO RGD:1323589 6480464 deguelin results in increased expression of TPX2 mRNA CTD PMID:33512557 dexamethasone multiple interactions ISO RGD:1323589 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TPX2 mRNA CTD PMID:28628672 dibenz[a,h]anthracene increases expression ISO RGD:1551918 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate decreases expression ISO RGD:1551918 6480464 Dibutyl Phthalate results in decreased expression of TPX2 mRNA CTD PMID:21266533 dichloroacetic acid increases expression ISO RGD:1551918 6480464 Dichloroacetic Acid results in increased expression of TPX2 mRNA CTD PMID:28962523 dioxygen multiple interactions EXP 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of TPX2 mRNA], [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of TPX2 mRNA CTD PMID:33729688 doxorubicin decreases expression ISO RGD:1323589 6480464 Doxorubicin results in decreased expression of TPX2 mRNA CTD PMID:29803840 Enterolactone multiple interactions ISO RGD:1323589 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TPX2 mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:1323589 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TPX2 protein CTD PMID:23301498 fenpyroximate increases expression ISO RGD:1323589 6480464 fenpyroximate results in increased expression of TPX2 mRNA CTD PMID:33512557 flutamide increases expression EXP 6480464 Flutamide results in increased expression of TPX2 mRNA CTD PMID:24793618 folic acid multiple interactions ISO RGD:1551918 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TPX2 mRNA CTD PMID:20938992 folic acid decreases expression ISO RGD:1551918 6480464 Folic Acid results in decreased expression of TPX2 mRNA CTD PMID:25629700 geraniol decreases expression ISO RGD:1323589 6480464 geraniol results in decreased expression of TPX2 mRNA CTD PMID:27683099 indometacin multiple interactions ISO RGD:1323589 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TPX2 mRNA CTD PMID:28628672 irinotecan decreases expression ISO RGD:1323589 6480464 Irinotecan metabolite results in decreased expression of TPX2 mRNA, Irinotecan results in decreased expression of TPX2 mRNA CTD PMID:15956246 ivermectin decreases expression ISO RGD:1323589 6480464 Ivermectin results in decreased expression of TPX2 protein CTD PMID:32959892 josamycin affects response to substance ISO RGD:1323589 6480464 TPX2 protein affects the susceptibility to Josamycin CTD PMID:31915244 L-methionine multiple interactions ISO RGD:1551918 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TPX2 mRNA CTD PMID:20938992 leflunomide decreases expression ISO RGD:1323589 6480464 leflunomide results in decreased expression of TPX2 mRNA CTD PMID:28988120 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of TPX2 mRNA CTD PMID:35283115 lucanthone decreases expression ISO RGD:1323589 6480464 Lucanthone results in decreased expression of TPX2 mRNA CTD PMID:21148553 menadione affects expression ISO RGD:1323589 6480464 Vitamin K 3 affects the expression of TPX2 mRNA CTD PMID:20044591 methamphetamine decreases methylation ISO RGD:1551918 6480464 Methamphetamine results in decreased methylation of TPX2 promoter CTD PMID:26307267 mitomycin C decreases expression ISO RGD:1551918 6480464 Mitomycin results in decreased expression of TPX2 mRNA CTD PMID:25270620 N-methyl-4-phenylpyridinium decreases expression ISO RGD:1323589 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TPX2 mRNA CTD PMID:24810058 N-Nitrosopyrrolidine decreases expression ISO RGD:1323589 6480464 N-Nitrosopyrrolidine results in decreased expression of TPX2 mRNA CTD PMID:32234424 nickel atom increases expression ISO RGD:1323589 6480464 Nickel results in increased expression of TPX2 mRNA CTD PMID:19031421 , PMID:25583101 niclosamide decreases expression ISO RGD:1323589 6480464 Niclosamide results in decreased expression of TPX2 mRNA CTD PMID:28284560 Nivalenol increases expression ISO RGD:1551918 6480464 nivalenol results in increased expression of TPX2 mRNA CTD PMID:35016910 NS-398 decreases expression ISO RGD:1323589 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of TPX2 mRNA CTD PMID:11494140 ozone multiple interactions ISO RGD:1551918 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TPX2 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in increased expression of TPX2 mRNA CTD PMID:34911549 palbociclib decreases expression ISO RGD:1323589 6480464 palbociclib results in decreased expression of TPX2 mRNA CTD PMID:22869556 paracetamol decreases expression ISO RGD:1323589 6480464 Acetaminophen results in decreased expression of TPX2 mRNA CTD PMID:26690555 , PMID:29067470 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of TPX2 mRNA CTD PMID:33387578 PCB138 multiple interactions ISO RGD:1551918 6480464 [2 more ... CTD PMID:25510870 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1323589 6480464 perfluorooctane sulfonic acid results in increased expression of TPX2 mRNA CTD PMID:27153767 perfluorooctanoic acid decreases expression ISO RGD:1323589 6480464 perfluorooctanoic acid results in decreased expression of TPX2 protein CTD PMID:26879310 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of TPX2 mRNA CTD PMID:31324951 phenobarbital affects expression ISO RGD:1551918 6480464 Phenobarbital affects the expression of TPX2 mRNA CTD PMID:23091169 phorbol 13-acetate 12-myristate increases expression ISO RGD:1323589 6480464 Tetradecanoylphorbol Acetate results in increased expression of TPX2 mRNA CTD PMID:19031421 picoxystrobin increases expression ISO RGD:1323589 6480464 picoxystrobin results in increased expression of TPX2 mRNA CTD PMID:33512557 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:1551918 6480464 Pregnenolone Carbonitrile results in increased expression of TPX2 mRNA CTD PMID:22698814 progesterone decreases expression ISO RGD:1323589 6480464 Progesterone results in decreased expression of TPX2 mRNA CTD PMID:21795739 pyrimidifen increases expression ISO RGD:1323589 6480464 pyrimidifen results in increased expression of TPX2 mRNA CTD PMID:33512557 resveratrol multiple interactions ISO RGD:1323589 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of TPX2 mRNA CTD PMID:19167446 resveratrol decreases expression ISO RGD:1551918 6480464 resveratrol results in decreased expression of TPX2 protein CTD PMID:25505154 resveratrol increases expression ISO RGD:1323589 6480464 resveratrol results in increased expression of TPX2 mRNA CTD PMID:19167446 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of TPX2 mRNA CTD PMID:28374803 rotenone increases expression ISO RGD:1323589 6480464 Rotenone results in increased expression of TPX2 mRNA CTD PMID:33512557 senecionine increases expression EXP 6480464 senecionine results in increased expression of TPX2 mRNA CTD PMID:32419051 Senkirkine increases expression EXP 6480464 senkirkine results in increased expression of TPX2 mRNA CTD PMID:32419051 silicon dioxide increases expression ISO RGD:1551918 6480464 Silicon Dioxide results in increased expression of TPX2 mRNA CTD PMID:29341224 sodium arsenite decreases expression ISO RGD:1551918 6480464 sodium arsenite results in decreased expression of TPX2 mRNA CTD PMID:17998272 sodium arsenite increases expression ISO RGD:1323589 6480464 sodium arsenite results in increased expression of TPX2 mRNA CTD PMID:29301061 SP2509 decreases expression ISO RGD:1323589 6480464 SP2509 results in decreased expression of TPX2 mRNA CTD PMID:29581250 sunitinib decreases expression ISO RGD:1323589 6480464 Sunitinib results in decreased expression of TPX2 mRNA CTD PMID:31533062 tebufenpyrad increases expression ISO RGD:1323589 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of TPX2 mRNA CTD PMID:33512557 testosterone multiple interactions ISO RGD:1323589 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of TPX2 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1323589 6480464 Testosterone results in decreased expression of TPX2 mRNA CTD PMID:21592394 tetrachloroethene increases expression ISO RGD:1323589 6480464 Tetrachloroethylene results in increased expression of TPX2 mRNA CTD PMID:19031421 tetrachloromethane affects expression ISO RGD:1551918 6480464 Carbon Tetrachloride affects the expression of TPX2 mRNA CTD PMID:17484886 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of TPX2 mRNA CTD PMID:31150632 tetrachloromethane increases expression ISO RGD:1551918 6480464 Carbon Tetrachloride results in increased expression of TPX2 mRNA CTD PMID:27339419 more ... thifluzamide increases expression ISO RGD:1323589 6480464 thifluzamide results in increased expression of TPX2 mRNA CTD PMID:33512557 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TPX2 mRNA CTD PMID:22659510 , PMID:23411599 titanium dioxide increases expression ISO RGD:1551918 6480464 titanium dioxide results in increased expression of TPX2 mRNA CTD PMID:23557971 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of TPX2 mRNA CTD PMID:30012374 titanium dioxide affects expression ISO RGD:1551918 6480464 titanium dioxide affects the expression of TPX2 mRNA CTD PMID:17656681 tremolite asbestos increases expression ISO RGD:1551918 6480464 tremolite results in increased expression of TPX2 mRNA CTD PMID:29279043 trichloroethene increases expression ISO RGD:1551918 6480464 Trichloroethylene results in increased expression of TPX2 mRNA CTD PMID:25549359 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of TPX2 mRNA CTD PMID:33387578 trichostatin A decreases expression ISO RGD:1323589 6480464 trichostatin A results in decreased expression of TPX2 mRNA CTD PMID:19606018 triclosan decreases expression ISO RGD:1323589 6480464 Triclosan results in decreased expression of TPX2 mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:1551918 6480464 trimellitic anhydride results in increased expression of TPX2 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:1323589 6480464 troglitazone results in decreased expression of TPX2 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO RGD:1551918 6480464 trovafloxacin results in decreased expression of TPX2 mRNA CTD PMID:35537566 tungsten decreases expression ISO RGD:1551918 6480464 Tungsten results in decreased expression of TPX2 mRNA CTD PMID:30912803 tunicamycin decreases expression ISO RGD:1323589 6480464 Tunicamycin results in decreased expression of TPX2 mRNA CTD PMID:29453283 valproic acid decreases methylation ISO RGD:1323589 6480464 Valproic Acid results in decreased methylation of TPX2 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1323589 6480464 Valproic Acid affects the expression of TPX2 mRNA CTD PMID:25979313 valproic acid affects expression ISO RGD:1551918 6480464 Valproic Acid affects the expression of TPX2 mRNA CTD PMID:17292431 zinc atom increases expression ISO RGD:1323589 6480464 Zinc deficiency results in increased expression of TPX2 mRNA CTD PMID:22171008 zinc(0) increases expression ISO RGD:1323589 6480464 Zinc deficiency results in increased expression of TPX2 mRNA CTD PMID:22171008 zoledronic acid decreases expression ISO RGD:1323589 6480464 zoledronic acid results in decreased expression of TPX2 mRNA CTD PMID:24714768