Gene: Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1) Rattus norvegicus
Symbol: Atp1a1
Name: ATPase Na+/K+ transporting subunit alpha 1
Description: ENCODES a protein that exhibits ADP binding; ankyrin binding; ATP binding; INVOLVED IN ATP hydrolysis coupled transmembrane transport; cellular response to mechanical stimulus; membrane hyperpolarization; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH Hearing Loss, Sensorineural; Hyperhomocysteinemia; Hypertension; FOUND IN caveola; endoplasmic reticulum; endosome; INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATPase, Na+/K+ transporting, alpha 1 polypeptide; ATPase, Na+K+ transporting, alpha 1; na(+)/K(+) ATPase alpha-1 subunit; Nkaa1b; sodium pump subunit alpha-1; sodium/potassium-transporting ATPase subunit alpha-1
Homo sapiens (human) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)  HGNC  AGR
Mus musculus (house mouse) : Atp1a1 (ATPase, Na+/K+ transporting, alpha 1 polypeptide)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Canis lupus familiaris (dog) : ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp1a1 (ATPase Na+/K+ transporting subunit alpha 1)
more info ...
Is Marker For: Strains:   SS.MNS-(Mme-Gca)/Ayd   SS.MNS-(Mme-D2Mit14)/Ayd   SS.MNS-(D2Mit6-Adh1)/Ayd  
QTLs:   Bp10   Bp158   Bp366  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02204,003,742 - 204,032,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02223,440,514 - 223,469,880 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42196,657,749 - 196,687,242 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12196,620,502 - 196,649,996 (-)NCBI
Celera2181,455,492 - 181,483,650 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp1a1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2167
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-12-05
Status: ACTIVE