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![]() Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (2,4,5-trichlorophenoxy)acetic acid | increases expression | ISO | RGD:1321942 | 6480464 | 2 more ... | CTD | PMID:18579281 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1321942 | 6480464 | Ethinyl Estradiol results in increased expression of COL15A1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1321941 | 6480464 | Ethinyl Estradiol results in increased expression of COL15A1 mRNA | CTD | PMID:18936297 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1321942 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL15A1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | affects expression | ISO | RGD:1321941 | 6480464 | Estradiol affects the expression of COL15A1 mRNA | CTD | PMID:14699072 | 17beta-estradiol | multiple interactions | ISO | RGD:1321941 | 6480464 | [Progesterone co-treated with Estradiol] results in increased expression of COL15A1 mRNA, Estradiol promotes the reaction [ESR2 protein affects the expression of COL15A1 mRNA] | CTD | PMID:20226447, PMID:20404318 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1321942 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL15A1 mRNA more ... | CTD | PMID:15667827 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1321941 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of COL15A1 mRNA | CTD | PMID:27913140 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1321942 | 6480464 | Tetrachlorodibenzodioxin affects the expression of COL15A1 mRNA | CTD | PMID:16962184, PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of COL15A1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1321941 | 6480464 | Tetrachlorodibenzodioxin affects the expression of COL15A1 mRNA | CTD | PMID:22298810 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1321941 | 6480464 | [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL15A1 mRNA | CTD | PMID:16997883 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1321942 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of COL15A1 mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1321942 | 6480464 | Fenretinide results in decreased expression of COL15A1 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of COL15A1 mRNA | CTD | PMID:24780913 | 8-bromo-3',5'-cyclic AMP | multiple interactions | ISO | RGD:1321941 | 6480464 | [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL15A1 mRNA | CTD | PMID:16997883 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of COL15A1 mRNA | CTD | PMID:28959563 | aldrin | increases expression | ISO | RGD:1321942 | 6480464 | Aldrin results in increased expression of COL15A1 mRNA | CTD | PMID:18579281 | aluminium oxide | increases expression | ISO | RGD:1321941 | 6480464 | Aluminum Oxide results in increased expression of COL15A1 mRNA | CTD | PMID:19464052 | antirheumatic drug | increases expression | ISO | RGD:1321941 | 6480464 | Antirheumatic Agents results in increased expression of COL15A1 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | multiple interactions | ISO | RGD:1321942 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to COL15A1 promoter] | CTD | PMID:19654925 | bisphenol A | decreases expression | ISO | RGD:1321942 | 6480464 | bisphenol A results in decreased expression of COL15A1 mRNA | CTD | PMID:23798566 | bisphenol A | increases expression | ISO | RGD:1321942 | 6480464 | bisphenol A results in increased expression of COL15A1 mRNA | CTD | PMID:30951980 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of COL15A1 mRNA | CTD | PMID:25181051 | bisphenol F | increases expression | ISO | RGD:1321942 | 6480464 | bisphenol F results in increased expression of COL15A1 mRNA | CTD | PMID:30951980 | butanal | increases expression | ISO | RGD:1321941 | 6480464 | butyraldehyde results in increased expression of COL15A1 mRNA | CTD | PMID:26079696 | chloroethene | increases expression | ISO | RGD:1321942 | 6480464 | Vinyl Chloride results in increased expression of COL15A1 mRNA | CTD | PMID:18579281 | cisplatin | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Cisplatin | CTD | PMID:25199881 | cisplatin | increases expression | ISO | RGD:1321941 | 6480464 | Cisplatin results in increased expression of COL15A1 mRNA | CTD | PMID:27392435 | clofibrate | increases expression | ISO | RGD:1321942 | 6480464 | Clofibrate results in increased expression of COL15A1 mRNA | CTD | PMID:17585979 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of COL15A1 mRNA | CTD | PMID:20187946 | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of COL15A1 mRNA | CTD | PMID:30556269 | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of COL15A1 mRNA | CTD | PMID:30556269 | copper(II) sulfate | increases expression | ISO | RGD:1321942 | 6480464 | Copper Sulfate results in increased expression of COL15A1 mRNA | CTD | PMID:18579281 | dexamethasone | multiple interactions | ISO | RGD:1321941 | 6480464 | [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of COL15A1 mRNA | CTD | PMID:16997883 | dexamethasone | decreases expression | ISO | RGD:1321941 | 6480464 | Dexamethasone results in decreased expression of COL15A1 mRNA | CTD | PMID:25047013 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of COL15A1 mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of COL15A1 mRNA] | CTD | PMID:20032058 | dibutyl phthalate | increases expression | ISO | RGD:1321942 | 6480464 | Dibutyl Phthalate results in increased expression of COL15A1 mRNA | CTD | PMID:21266533 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of COL15A1 mRNA | CTD | PMID:21551480 | doxorubicin | increases expression | ISO | RGD:1321942 | 6480464 | Doxorubicin results in increased expression of COL15A1 mRNA | CTD | PMID:15033991 | doxorubicin | decreases expression | ISO | RGD:1321941 | 6480464 | Doxorubicin results in decreased expression of COL15A1 mRNA | CTD | PMID:29803840 | doxorubicin | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Doxorubicin | CTD | PMID:25199881 | doxorubicin | decreases expression | ISO | RGD:1321942 | 6480464 | Doxorubicin results in decreased expression of COL15A1 mRNA | CTD | PMID:16243910 | etoposide | affects response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of COL15A1 mRNA | CTD | PMID:27387713 | graphite | increases expression | EXP | | 6480464 | Graphite results in increased expression of COL15A1 mRNA | CTD | PMID:29933104 | isoprenaline | decreases expression | ISO | RGD:1321942 | 6480464 | Isoproterenol results in decreased expression of COL15A1 mRNA | CTD | PMID:20003209 | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of COL15A1 mRNA | CTD | PMID:11578147 | lead diacetate | decreases expression | ISO | RGD:1321942 | 6480464 | lead acetate results in decreased expression of COL15A1 mRNA | CTD | PMID:22613225 | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of COL15A1 mRNA | CTD | PMID:28801915 | methotrexate | affects response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | methotrexate | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Methotrexate | CTD | PMID:25199881 | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of COL15A1 mRNA | CTD | PMID:28801915 | nickel sulfate | decreases expression | ISO | RGD:1321942 | 6480464 | nickel sulfate results in decreased expression of COL15A1 mRNA | CTD | PMID:16166746 | paclitaxel | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Paclitaxel | CTD | PMID:25199881 | paracetamol | affects expression | ISO | RGD:1321942 | 6480464 | Acetaminophen affects the expression of COL15A1 mRNA | CTD | PMID:17562736 | paricalcitol | multiple interactions | ISO | RGD:1321941 | 6480464 | [Phosphorus co-treated with paricalcitol] results in increased expression of COL15A1 mRNA | CTD | PMID:17715259 | phenobarbital | increases expression | ISO | RGD:1321942 | 6480464 | Phenobarbital results in increased expression of COL15A1 mRNA | CTD | PMID:19482888 | phenobarbital | affects expression | ISO | RGD:1321942 | 6480464 | Phenobarbital affects the expression of COL15A1 mRNA | CTD | PMID:23091169 | phosphorus atom | multiple interactions | ISO | RGD:1321941 | 6480464 | [Phosphorus co-treated with paricalcitol] results in increased expression of COL15A1 mRNA | CTD | PMID:17715259 | phosphorus(.) | multiple interactions | ISO | RGD:1321941 | 6480464 | [Phosphorus co-treated with paricalcitol] results in increased expression of COL15A1 mRNA | CTD | PMID:17715259 | pirinixic acid | multiple interactions | ISO | RGD:1321942 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of COL15A1 mRNA | CTD | PMID:19710929 | pirinixic acid | decreases expression | ISO | RGD:1321942 | 6480464 | pirinixic acid results in decreased expression of COL15A1 mRNA | CTD | PMID:23811191 | potassium dichromate | increases expression | ISO | RGD:1321942 | 6480464 | Potassium Dichromate results in increased expression of COL15A1 mRNA | CTD | PMID:23608068 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | RGD:1321942 | 6480464 | Pregnenolone Carbonitrile results in decreased expression of COL15A1 mRNA | CTD | PMID:28903501 | progesterone | multiple interactions | ISO | RGD:1321941 | 6480464 | [Progesterone co-treated with Estradiol] results in increased expression of COL15A1 mRNA | CTD | PMID:20226447 | progesterone | increases expression | ISO | RGD:1321941 | 6480464 | Progesterone results in increased expression of COL15A1 mRNA | CTD | PMID:20226447 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of COL15A1 mRNA | CTD | PMID:28374803 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of COL15A1 mRNA | CTD | PMID:22431001 | sodium arsenite | multiple interactions | ISO | RGD:1321941 | 6480464 | sodium arsenite results in decreased expression of and affects the splicing of COL15A1 mRNA | CTD | PMID:25879800 | sodium fluoride | decreases expression | ISO | RGD:1321942 | 6480464 | Sodium Fluoride results in decreased expression of COL15A1 protein | CTD | PMID:28918527 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of COL15A1 mRNA | CTD | PMID:19281266 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of COL15A1 mRNA] | CTD | PMID:20032058 | tetrachloromethane | increases expression | ISO | RGD:1321942 | 6480464 | Carbon Tetrachloride results in increased expression of COL15A1 mRNA | CTD | PMID:17484886 | titanium dioxide | decreases expression | ISO | RGD:1321942 | 6480464 | titanium dioxide results in decreased expression of COL15A1 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | ISO | RGD:1321942 | 6480464 | titanium dioxide results in increased expression of COL15A1 mRNA | CTD | PMID:29264374 | topotecan | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Topotecan | CTD | PMID:25199881 | valproic acid | affects expression | ISO | RGD:1321941 | 6480464 | Valproic Acid affects the expression of COL15A1 mRNA | CTD | PMID:25979313 | vincristine | decreases response to substance | ISO | RGD:1321941 | 6480464 | COL15A1 mRNA results in decreased susceptibility to Vincristine | CTD | PMID:25199881 | |
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1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | GOA data from the GO Consortium |
3. | MGD data from the GO Consortium |
4. | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
5. | RGD automated data pipeline |
6. | RGD automated import pipeline for gene-chemical interactions |
Col15a1 (Rattus norvegicus - Norway rat) |
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COL15A1 (Homo sapiens - human) |
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Col15a1 (Mus musculus - house mouse) |
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Col15a1 (Chinchilla lanigera - long-tailed chinchilla) |
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COL15A1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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COL15A1 (Canis lupus familiaris - dog) |
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Col15a1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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COL15A1 (Sus scrofa - pig) |
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D5Rat10 |
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D5Rat227 |
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D5Mco4 |
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RH131575 |
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RH138615 |
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BI282987 |
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The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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High | ||||||||||||||||
Medium | 8 | 19 | 8 | 4 | 2 | 4 | 7 | 16 | ||||||||
Low | 14 | 14 | 17 | 7 | 1 | 3 | 4 | 26 | 21 | 4 | 11 | 22 | 19 | 8 | 8 | |
Below cutoff | 8 | 6 | 4 | 18 |
RefSeq Transcripts | NM_001100535 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
GenBank Nucleotide | AABR07048114 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AABR07048115 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AABR07048116 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01036547 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01036548 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01036549 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01036550 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AAHX01036551 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AC092857 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC098815 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473962 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ228852 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | NM_001100535 ⟹ NP_001094005 | |||||||||||||||||||
RefSeq Status: | VALIDATED | |||||||||||||||||||
Type: | CODING | |||||||||||||||||||
Position: |
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Sequence: |
AGCTATCCCAGGCGGCCCTAAGGTTGTGGAGCTCTGTGTCTGCATGCAGGACTTTCCTCGCGTGhide sequence |
Protein RefSeqs | NP_001094005 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAH98815 | (Get FASTA) | NCBI Sequence Viewer |
EDL98855 | (Get FASTA) | NCBI Sequence Viewer | |
EDL98856 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001094005 ⟸ NM_001100535 |
- Peptide Label: | precursor |
- UniProtKB: | A0A0G2JV12 (UniProtKB/TrEMBL) |
- Sequence: |
MTHRRTAQGRRPRWLLSIISTLLSTVLQTRAATGSASQDHLDLTELIGVPLPSSVSFVTGYGGFhide sequence |
RGD ID: | 13693731 | |||||||||
Promoter ID: | EPDNEW_R4243 | |||||||||
Type: | initiation region | |||||||||
Name: | Col15a1_1 | |||||||||
Description: | collagen type XV alpha 1 chain | |||||||||
SO ACC ID: | SO:0000170 | |||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
Experiment Methods: | Single-end sequencing. | |||||||||
Position: |
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Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
5 | 62949288 | 62949289 | T | G | snv | WKY/N (MCW) |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1310820 | AgrOrtholog |
Ensembl Genes | ENSRNOG00000060381 | ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Protein | ENSRNOP00000069309 | ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000088385 | ENTREZGENE, UniProtKB/TrEMBL |
Gene3D-CATH | 3.10.100.10 | UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7377145 | IMAGE-MGC_LOAD |
InterPro | C-type_lectin-like | UniProtKB/TrEMBL |
C-type_lectin_fold | UniProtKB/TrEMBL | |
COL15A1 | UniProtKB/TrEMBL | |
Collagen | UniProtKB/TrEMBL | |
Collagenase_NC10/endostatin | UniProtKB/TrEMBL | |
ConA-like_subgrp | UniProtKB/TrEMBL | |
Laminin_G | UniProtKB/TrEMBL | |
KEGG Report | rno:298069 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:112860 | IMAGE-MGC_LOAD |
NCBI Gene | 298069 | ENTREZGENE |
PANTHER | PTHR24023:SF912 | UniProtKB/TrEMBL |
Pfam | Collagen | UniProtKB/TrEMBL |
Endostatin | UniProtKB/TrEMBL | |
PhenoGen | Col15a1 | PhenoGen |
SMART | LamG | UniProtKB/TrEMBL |
TSPN | UniProtKB/TrEMBL | |
Superfamily-SCOP | C-type_lectin_fold | UniProtKB/TrEMBL |
ConA_like_lec_gl | UniProtKB/TrEMBL | |
UniGene | Rn.31832 | ENTREZGENE |
UniProt | A0A0G2JV12 | ENTREZGENE, UniProtKB/TrEMBL |
Q4G024_RAT | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2016-06-01 | Col15a1 | collagen type XV alpha 1 chain | Col15a1 | collagen, type XV, alpha 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-03 | Col15a1 | collagen, type XV, alpha 1 | Col15a1 | procollagen, type XV | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-12-06 | Col15a1 | procollagen, type XV | Col15a1_predicted | procollagen, type XV (predicted) | Symbol and Name updated | 1559027 | APPROVED |
2005-01-12 | Col15a1_predicted | procollagen, type XV (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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More on Col15a1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
RGD Object Information | |
RGD ID: | 1310820 |
Created: | 2005-01-12 |
Species: | Rattus norvegicus |
Last Modified: | 2019-11-27 |
Status: | ACTIVE |
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.