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Gene: Smyd2 (SET and MYND domain containing 2) Rattus norvegicus
Symbol: Smyd2
Name: SET and MYND domain containing 2
Description: Predicted to have RNA polymerase II complex binding activity; histone methyltransferase activity (H3-K36 specific); and p53 binding activity. Involved in heart development. Localizes to the cytosol and nucleus. Orthologous to human SMYD2 (SET and MYND domain containing 2); PARTICIPATES IN histone modification pathway; methionine cycle/metabolic pathway; p53 signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histone methyltransferase SMYD2; HSKM-B; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2
Homo sapiens (human) : SMYD2 (SET and MYND domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Smyd2 (SET and MYND domain containing 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smyd2 (SET and MYND domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMYD2 (SET and MYND domain containing 2)
Canis lupus familiaris (dog) : SMYD2 (SET and MYND domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smyd2 (SET and MYND domain containing 2)
Sus scrofa (pig) : SMYD2 (SET and MYND domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.013108,642,156 - 108,686,293 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,642,156 - 108,686,290 (+)Ensembl
Rnor_5.013113,261,746 - 113,302,399 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413106,160,147 - 106,201,473 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113106,349,462 - 106,390,567 (-)NCBI
Celera13100,910,865 - 100,950,701 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Smyd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727785
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.