Smyd2 (SET and MYND domain containing 2) - Rat Genome Database

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Gene: Smyd2 (SET and MYND domain containing 2) Mus musculus
Analyze
Symbol: Smyd2
Name: SET and MYND domain containing 2
RGD ID: 1552013
MGI Page MGI
Description: Enables RNA polymerase II complex binding activity and histone H3K36 methyltransferase activity. Involved in negative regulation of cell population proliferation and peptidyl-lysine dimethylation. Located in cytosol and nucleus. Is expressed in several structures, including gonad; heart; hemolymphoid system gland; nasal cavity epithelium; and nervous system. Orthologous to human SMYD2 (SET and MYND domain containing 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110020E07Rik; 4930402C15; histone methyltransferase SMYD2; KMT3C; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2; Zmynd1; Zmynd14
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391189,612,689 - 189,654,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1189,612,689 - 189,654,560 (-)EnsemblGRCm39 Ensembl
GRCm381189,880,492 - 189,922,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1189,880,492 - 189,922,363 (-)EnsemblGRCm38mm10GRCm38
MGSCv371191,704,371 - 191,746,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361191,581,280 - 191,623,076 (-)NCBIMGSCv36mm8
Celera1196,790,858 - 196,832,656 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map195.03NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,ISO)
cytosol  (IDA)
nucleus  (IBA,IDA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. Targeting protein lysine methylation and demethylation in cancers. He Y, etal., Acta Biochim Biophys Sin (Shanghai). 2012 Jan;44(1):70-9. doi: 10.1093/abbs/gmr109.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Modes of p53 regulation. Kruse JP and Gu W, Cell. 2009 May 15;137(4):609-22. doi: 10.1016/j.cell.2009.04.050.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16805913   PMID:17108971  
PMID:17967808   PMID:18022353   PMID:18799693   PMID:20305823   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22241783   PMID:22862948   PMID:23047121   PMID:25014164   PMID:25077969  
PMID:25583990   PMID:26988419   PMID:27655694   PMID:28604386   PMID:30973865   PMID:32325033   PMID:34015314   PMID:34143514   PMID:35297562   PMID:36270984   PMID:37615725   PMID:38243079  
PMID:38355793   PMID:38770649  


Genomics

Comparative Map Data
Smyd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391189,612,689 - 189,654,758 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1189,612,689 - 189,654,560 (-)EnsemblGRCm39 Ensembl
GRCm381189,880,492 - 189,922,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1189,880,492 - 189,922,363 (-)EnsemblGRCm38mm10GRCm38
MGSCv371191,704,371 - 191,746,167 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361191,581,280 - 191,623,076 (-)NCBIMGSCv36mm8
Celera1196,790,858 - 196,832,656 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map195.03NCBI
SMYD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,281,159 - 214,337,131 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1214,281,102 - 214,337,131 (+)EnsemblGRCh38hg38GRCh38
GRCh371214,454,502 - 214,510,474 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,521,199 - 212,577,097 (+)NCBINCBI36Build 36hg18NCBI36
Build 341210,842,970 - 210,898,868NCBI
Celera1187,677,508 - 187,733,362 (+)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1185,129,703 - 185,185,600 (+)NCBIHuRef
CHM1_11215,726,941 - 215,782,851 (+)NCBICHM1_1
T2T-CHM13v2.01213,520,680 - 213,576,627 (+)NCBIT2T-CHM13v2.0
Smyd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813103,956,470 - 103,997,774 (-)NCBIGRCr8
mRatBN7.213101,425,270 - 101,466,576 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13101,425,273 - 101,466,576 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13103,940,656 - 103,981,564 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013105,329,429 - 105,370,669 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013102,534,981 - 102,578,302 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013108,642,156 - 108,686,293 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,642,156 - 108,686,290 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013113,261,746 - 113,302,399 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413106,160,147 - 106,201,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113106,349,462 - 106,390,567 (-)NCBI
Celera13100,910,865 - 100,950,701 (-)NCBICelera
Cytogenetic Map13q26NCBI
Smyd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554063,465,924 - 3,509,156 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554063,467,123 - 3,509,156 (-)NCBIChiLan1.0ChiLan1.0
SMYD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2135,065,100 - 35,121,132 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1135,029,402 - 35,085,432 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01189,849,167 - 189,905,193 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11194,729,116 - 194,761,043 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1194,729,116 - 194,761,045 (+)Ensemblpanpan1.1panPan2
SMYD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1712,281,581 - 12,331,294 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl712,281,710 - 12,331,164 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha711,855,760 - 11,905,351 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0711,991,481 - 12,041,301 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl711,991,446 - 12,044,237 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1711,915,043 - 11,964,795 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0712,019,583 - 12,068,986 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0712,143,792 - 12,193,251 (+)NCBIUU_Cfam_GSD_1.0
Smyd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934461,907,871 - 61,955,361 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366283,918,230 - 3,965,387 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366283,917,898 - 3,965,382 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMYD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9129,263,526 - 129,316,349 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19129,263,524 - 129,316,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29142,158,967 - 142,212,600 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMYD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12515,236,773 - 15,293,154 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2515,235,653 - 15,293,153 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605515,711,719 - 15,767,873 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smyd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477119,441,456 - 19,487,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477119,441,452 - 19,485,897 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:602
Count of miRNA genes:395
Interacting mature miRNAs:449
Transcripts:ENSMUST00000027897, ENSMUST00000130804, ENSMUST00000132289, ENSMUST00000144452
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157456299191456436Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1167954584195154279Mouse
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172303451195154279Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160097157194097157Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164143227190534272Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160097157194097157Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168213823195154279Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1155831765189831892Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161201261195154279Mouse
1302023Orch4_mautoimmune orchitis resistance 4 (mouse)Not determined1175211318195154279Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167462514195154279Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157456299191456436Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167462514195154279Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170379500195154279Mouse
1357620Aaj1_manxiety in A/J 1 (mouse)Not determined1180832317191851043Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159262573193262693Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157456299191456436Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1171983110195154279Mouse
11532690Sluc37_msusceptibility to lung cancer 37 (mouse)1175468817194111528Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155716221189716369Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158468817192468938Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160112768194112883Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157456299191456436Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1165873675195154279Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158468817192468938Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158468817192468938Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172303451195154279Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158468817192468938Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162145207194111528Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172303451195154279Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined155831765189831892Mouse
12792983Liq1_mlimb inflammation QTL 1 (mouse)1167586086191225397Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158468817192468938Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1155831765189831892Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155716221189716369Mouse
1300727Mptp1_mMPTP sensitivity 1 (mouse)Not determined1171632048192681050Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155716221189716369Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167462514195154279Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1155831765189831892Mouse
1357692Axtq1_manxiety QTL 1 (mouse)Not determined1180832317191851043Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172632197195154279Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172532197195154279Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157456299191456436Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157456299191456436Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157456299191456436Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155721528189722608Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158468817192468938Mouse

Markers in Region
D1Mit117  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381189,923,915 - 189,924,016UniSTSGRCm38
MGSCv371191,747,794 - 191,747,895UniSTSGRCm37
Celera1196,834,283 - 196,834,386UniSTS
Cytogenetic Map1H6UniSTS
cM Map1106.1UniSTS
Whitehead Genetic1110.4UniSTS
Whitehead_YAC1 UniSTS
D1Mit409.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381189,896,839 - 189,896,971UniSTSGRCm38
MGSCv371191,720,718 - 191,720,850UniSTSGRCm37
Celera1196,807,031 - 196,807,163UniSTS
Cytogenetic Map1H6UniSTS
cM Map1106.3UniSTS
cM Map1 UniSTS
Whitehead Genetic1110.278UniSTS
Whitehead_YAC1 UniSTS
D1Mit409  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381189,896,713 - 189,896,809UniSTSGRCm38
MGSCv371191,720,592 - 191,720,688UniSTSGRCm37
Celera1196,806,903 - 196,807,001UniSTS
Cytogenetic Map1H6UniSTS
cM Map1106.3UniSTS
Whitehead Genetic1110.4UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017320186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC140250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W76826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000027897   ⟹   ENSMUSP00000027897
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1189,612,689 - 189,654,560 (-)Ensembl
GRCm38.p6 Ensembl1189,880,492 - 189,922,363 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1189,612,691 - 189,621,199 (-)Ensembl
GRCm38.p6 Ensembl1189,880,494 - 189,889,002 (-)Ensembl
Ensembl Acc Id: ENSMUST00000132289
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1189,612,839 - 189,614,569 (-)Ensembl
GRCm38.p6 Ensembl1189,880,642 - 189,882,372 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144452
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1189,617,243 - 189,654,450 (-)Ensembl
GRCm38.p6 Ensembl1189,885,046 - 189,922,253 (-)Ensembl
RefSeq Acc Id: NM_026796   ⟹   NP_081072
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391189,612,689 - 189,654,488 (-)NCBI
GRCm381189,880,492 - 189,922,291 (-)NCBI
MGSCv371191,704,371 - 191,746,167 (-)RGD
Celera1196,790,858 - 196,832,656 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497146   ⟹   XP_006497209
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391189,612,689 - 189,654,739 (-)NCBI
GRCm381189,880,492 - 189,922,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006497147   ⟹   XP_006497210
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391189,618,717 - 189,654,758 (-)NCBI
GRCm381189,886,520 - 189,922,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017320186   ⟹   XP_017175675
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391189,612,689 - 189,654,414 (-)NCBI
GRCm381189,880,492 - 189,922,217 (-)NCBI
Sequence:
RefSeq Acc Id: NP_081072   ⟸   NM_026796
- UniProtKB: Q8R5A0 (UniProtKB/Swiss-Prot),   Q3UBQ2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006497209   ⟸   XM_006497146
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006497210   ⟸   XM_006497147
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017175675   ⟸   XM_017320186
- Peptide Label: isoform X3
- UniProtKB: Q9D177 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000027897   ⟸   ENSMUST00000027897
Protein Domains
SET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R5A0-F1-model_v2 AlphaFold Q8R5A0 1-433 view protein structure

Promoters
RGD ID:6876072
Promoter ID:EPDNEW_M1487
Type:initiation region
Name:Smyd2_1
Description:Mus musculus SET and MYND domain containing 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381189,922,297 - 189,922,357EPDNEW
RGD ID:6848557
Promoter ID:MM_TRO:725
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:MTR015010.1.3069.5
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,704,046 - 191,704,546 (-)MPROMDB
RGD ID:6818496
Promoter ID:MM_KWN:3274
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000050715
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,706,216 - 191,706,716 (-)MPROMDB
RGD ID:6848556
Promoter ID:MM_TRO:726
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4
Transcripts:MTR015010.1.3069.3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,707,506 - 191,708,006 (-)MPROMDB
RGD ID:6818497
Promoter ID:MM_KWN:3275
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:OTTMUST00000041404,   UC007EAY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,712,536 - 191,713,036 (-)MPROMDB
RGD ID:6818500
Promoter ID:MM_KWN:3276
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:UC007EAZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,733,996 - 191,734,496 (-)MPROMDB
RGD ID:6818498
Promoter ID:MM_KWN:3277
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000041402,   OTTMUST00000041403
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361191,745,924 - 191,746,424 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915889 AgrOrtholog
Ensembl Genes ENSMUSG00000026603 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027897 ENTREZGENE
  ENSMUST00000027897.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/Swiss-Prot
InterPro H3K4_H4K5_MeTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMYD2_SET UniProtKB/Swiss-Prot
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_MYND UniProtKB/Swiss-Prot
KEGG Report mmu:226830 UniProtKB/Swiss-Prot
MGD MGI:1915889 ENTREZGENE
NCBI Gene Smyd2 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SMYD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  N-LYSINE METHYLTRANSFERASE SMYD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-MYND UniProtKB/Swiss-Prot
PhenoGen Smyd2 PhenoGen
PROSITE SET UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/Swiss-Prot
  ZF_MYND_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q3UBQ2 ENTREZGENE
  Q8R5A0 ENTREZGENE
  Q9D177 ENTREZGENE, UniProtKB/TrEMBL
  SMYD2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3UBQ2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-26 Smyd2  SET and MYND domain containing 2  1110020E07Rik  RIKEN cDNA 1110020E07 gene  Symbol and/or name updated 27372883 PROVISIONAL
2024-08-21 1110020E07Rik  RIKEN cDNA 1110020E07 gene  Smyd2  SET and MYND domain containing 2  Symbol and/or name change 5135510 APPROVED