Gene: Wrn (Werner syndrome RecQ like helicase) Rattus norvegicus
Symbol: Wrn
Name: Werner syndrome RecQ like helicase
Description: ENCODES a protein that exhibits chromatin binding; 3'-5' DNA helicase activity (ortholog); 3'-5' exonuclease activity (ortholog); INVOLVED IN brain development; base-excision repair (ortholog); cell aging (ortholog); ASSOCIATED WITH Aging, Premature (ortholog); breast cancer, familial (ortholog); Breast Neoplasms (ortholog); FOUND IN neuron projection; centrosome (ortholog); chromosome, telomeric region (ortholog); INTERACTS WITH cisplatin; ketamine; sodium arsenite
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290805; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome, RecQ helicase-like
Homo sapiens (human) : WRN (Werner syndrome RecQ like helicase)  HGNC  AGR
Mus musculus (house mouse) : Wrn (Werner syndrome RecQ like helicase)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Wrn (Werner syndrome RecQ like helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : WRN (Werner syndrome RecQ like helicase)
Canis lupus familiaris (dog) : WRN (Werner syndrome RecQ like helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wrn (Werner syndrome RecQ like helicase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01662,483,773 - 62,619,018 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01662,148,560 - 62,283,748 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41662,535,144 - 62,668,700 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1656,796,927 - 56,929,877 (+)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Wrn
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1564788
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2017-12-05
Status: ACTIVE