Gene: Celsr2 (cadherin, EGF LAG seven-pass G-type receptor 2) Rattus norvegicus
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Symbol: Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Description: ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); INVOLVED IN dendrite morphogenesis; regulation of cell-cell adhesion; spermatogenesis; ASSOCIATED WITH autistic disorder (ortholog); Developmental Disabilities (ortholog); endometrial hyperplasia (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; endosulfan
AGR Description: Predicted to have G protein-coupled receptor activity and calcium ion binding activity; involved in dendrite morphogenesis, regulation of cell-cell adhesion, and spermatogenesis; predicted to localize to the cytoplasm and plasma membrane; orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2).
Merged Description: Predicted to have G protein-coupled receptor activity and calcium ion binding activity; involved in dendrite morphogenesis, regulation of cell-cell adhesion, and spermatogenesis; predicted to localize to the cytoplasm and plasma membrane; orthologous to human CELSR2 (cadherin EGF LAG seven-pass G-type receptor 2); INTERACTS WITH ammonium chloride; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cadherin EGF LAG seven-pas G-type receptor 2; cadherin EGF LAG seven-pass G-type receptor 2; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); flamingo-like protein celsr2; Flamingo1; Megf3; multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02211,183,410 - 211,207,458 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02230,653,341 - 230,677,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,960,513 - 203,983,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,923,277 - 203,943,562 (-)NCBI
Celera2188,676,929 - 188,699,559 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Celsr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69237
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.