(-)-demecolcine decreases expression ISO RGD:731551 6480464 Demecolcine results in decreased expression of GCLM mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate increases expression ISO RGD:735691 6480464 epigallocatechin gallate results in increased expression of GCLM mRNA CTD PMID:25585349 (E)-cinnamyl alcohol increases expression ISO RGD:731551 6480464 cinnamyl alcohol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... (R)-lipoic acid increases expression ISO RGD:731551 6480464 Thioctic Acid results in increased expression of GCLM mRNA CTD PMID:16249512 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA], Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 (R,R,R)-alpha-tocopherol multiple interactions ISO RGD:731551 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:24530478 (S)-naringenin increases expression ISO RGD:731551 6480464 naringenin results in increased expression of GCLM protein CTD PMID:31254498 (S)-naringenin multiple interactions ISO RGD:731551 6480464 NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLM protein] CTD PMID:31254498 1,1'-azobis(N,N-dimethylformamide) increases expression EXP 6480464 Diamide results in increased expression of GCLM mRNA, Diamide results in increased expression of GCLM protein CTD PMID:15115889 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of GCLM mRNA CTD PMID:17984292 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:735691 6480464 o, p'-DDT affects the expression of GCLM mRNA CTD PMID:18925944 1,1-dichloroethene decreases expression ISO RGD:735691 6480464 vinylidene chloride results in decreased expression of GCLM mRNA CTD PMID:26682919 1,2-dimethylhydrazine affects expression ISO RGD:735691 6480464 1, 2-Dimethylhydrazine affects the expression of GCLM mRNA CTD PMID:22206623 1,3-benzothiazole-2-thiol increases expression ISO RGD:731551 6480464 captax results in increased expression of GCLM mRNA CTD PMID:23999411 , PMID:24211530 1,3-dichloropropan-2-ol increases expression EXP 6480464 1, 3-dichloro-2-propanol results in increased expression of GCLM mRNA CTD PMID:26143167 1,4-benzoquinone increases expression ISO RGD:731551 6480464 quinone results in increased expression of GCLM protein CTD PMID:21059386 1,4-phenylenediamine increases expression ISO RGD:731551 6480464 4-phenylenediamine results in increased expression of GCLM mRNA CTD PMID:16314067 more ... 1-bromopropane multiple interactions ISO RGD:735691 6480464 NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA] CTD PMID:20211940 1-bromopropane increases expression ISO RGD:735691 6480464 1-bromopropane results in increased expression of GCLM mRNA CTD PMID:20211940 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:731551 6480464 Dinitrochlorobenzene results in increased expression of GCLM mRNA CTD PMID:20146380 more ... 1-chloro-2,4-dinitrobenzene multiple interactions ISO RGD:731551 6480464 NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] CTD PMID:27965148 1-fluoro-2,4-dinitrobenzene increases expression ISO RGD:731551 6480464 Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO RGD:735691 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:31187328 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of GCLM mRNA CTD PMID:20551477 1-naphthyl isothiocyanate multiple interactions ISO RGD:731551 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of GCLM mRNA CTD PMID:27344345 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with epomediol] results in increased activity of GCLM protein CTD PMID:12071332 17beta-estradiol increases expression ISO RGD:731551 6480464 Estradiol results in increased expression of GCLM mRNA CTD PMID:20106945 , PMID:31614463 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of GCLM mRNA CTD PMID:22389237 17beta-estradiol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:731551 6480464 [2 more ... CTD PMID:25305463 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:735691 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:735691 6480464 GCLM protein affects the reaction [2 more ... CTD PMID:25797475 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:731551 6480464 2 more ... CTD PMID:25305463 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:23829299 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735691 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:18163543 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731551 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:11489354 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735691 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of GCLM mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735691 6480464 Tetrachlorodibenzodioxin affects the expression of GCLM mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731551 6480464 Tetrachlorodibenzodioxin affects the expression of GCLM mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases response to substance ISO RGD:735691 6480464 GCLM results in decreased susceptibility to Tetrachlorodibenzodioxin CTD PMID:22082335 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GCLM mRNA CTD PMID:21215274 2,3-dimethoxynaphthalene-1,4-dione decreases response to substance ISO RGD:735691 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2 more ... CTD PMID:23315585 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:731551 6480464 Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA CTD PMID:22609641 2-(chloromethyl)pyridine increases expression ISO RGD:731551 6480464 2-chloromethylpyridine results in increased expression of GCLM mRNA CTD PMID:26198647 2-acetamidofluorene multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO RGD:735691 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA] more ... CTD PMID:28887131 , PMID:35691465 2-bromo-2-(bromomethyl)pentanedinitrile increases expression ISO RGD:731551 6480464 1 more ... CTD PMID:23999411 , PMID:27965148 2-Ethylhexyl acrylate increases expression ISO RGD:731551 6480464 2-ethylhexyl acrylate results in increased expression of GCLM mRNA CTD PMID:27965148 2-hydroxyethyl methacrylate increases expression ISO RGD:731551 6480464 hydroxyethyl methacrylate results in increased expression of GCLM mRNA, hydroxyethyl methacrylate results in increased expression of GCLM protein CTD PMID:30497689 2-hydroxypropanoic acid increases expression ISO RGD:731551 6480464 Lactic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 2-tert-butylhydroquinone increases expression ISO RGD:735691 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:12007577 more ... 2-tert-butylhydroquinone decreases expression ISO RGD:731551 6480464 2-tert-butylhydroquinone results in decreased expression of GCLM mRNA CTD PMID:35724838 2-tert-butylhydroquinone multiple interactions ISO RGD:731551 6480464 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] more ... CTD PMID:24632381 , PMID:25305463 2-tert-butylhydroquinone increases expression ISO RGD:731551 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:12081989 , PMID:25003661 2-tert-butylhydroquinone multiple interactions ISO RGD:735691 6480464 NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA] CTD PMID:19328227 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:10978506 3,7-dihydropurine-6-thione increases expression ISO RGD:731551 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 3-Hydroxybenzo[a]pyrene increases expression ISO RGD:731551 6480464 3-hydroxybenzo(a)pyrene results in increased expression of GCLM mRNA CTD PMID:26238291 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735691 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 3-phenylprop-2-enal multiple interactions ISO RGD:731551 6480464 [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA CTD PMID:20351055 3-phenylprop-2-enal increases expression ISO RGD:731551 6480464 cinnamaldehyde results in increased expression of GCLM mRNA CTD PMID:17178418 more ... 3H-1,2-dithiole-3-thione affects expression EXP 6480464 1, 2-dithiol-3-thione affects the expression of GCLM mRNA CTD PMID:19162173 3H-1,2-dithiole-3-thione multiple interactions ISO RGD:735691 6480464 [1, 2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA CTD PMID:22495766 4,4'-methylene-bis-(2-chloroaniline) increases expression ISO RGD:731551 6480464 Methylenebis(chloroaniline) results in increased expression of GCLM mRNA CTD PMID:26198647 4,4'-sulfonyldiphenol increases expression ISO RGD:731551 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of GCLM protein CTD PMID:34186270 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO RGD:731551 6480464 Oxazolone results in increased expression of GCLM mRNA CTD PMID:23999411 4-hydroxynon-2-enal increases expression ISO RGD:735691 6480464 4-hydroxy-2-nonenal results in increased expression of GCLM mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO RGD:735691 6480464 Fenretinide results in increased expression of GCLM mRNA CTD PMID:28973697 4-nitro-1,2-phenylenediamine increases expression ISO RGD:731551 6480464 1, 2-diamino-4-nitrobenzene results in increased expression of GCLM mRNA CTD PMID:26198647 4-nitrobenzyl bromide increases expression ISO RGD:731551 6480464 4-nitrobenzyl bromide results in increased expression of GCLM mRNA CTD PMID:23999411 4-phenyl-3-furoxancarbonitrile increases expression ISO RGD:731551 6480464 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 5-fluorouracil affects response to substance ISO RGD:731551 6480464 GCLM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 7,8-dihydroxycoumarin increases expression ISO RGD:731551 6480464 daphnetin results in increased expression of GCLM protein CTD PMID:30738023 7beta-aminocephalosporanic acid increases expression ISO RGD:731551 6480464 7-aminocephalosporanic acid results in increased expression of GCLM mRNA CTD PMID:24211530 [6]-Shogaol increases expression ISO RGD:731551 6480464 shogaol metabolite results in increased expression of GCLM protein, shogaol results in increased expression of GCLM protein CTD PMID:25148906 abietic acid increases expression ISO RGD:731551 6480464 abietic acid results in increased expression of GCLM mRNA CTD PMID:27965148 acetylcholine affects response to substance ISO RGD:731551 6480464 GCLM gene SNP affects the susceptibility to Acetylcholine CTD PMID:12975258 acrolein increases expression ISO RGD:735691 6480464 Acrolein results in increased expression of GCLM mRNA CTD PMID:12763045 acrolein increases expression ISO RGD:731551 6480464 Acrolein results in increased expression of GCLM mRNA CTD PMID:24211530 acrylamide multiple interactions ISO RGD:731551 6480464 salvin inhibits the reaction [Acrylamide results in decreased expression of GCLM mRNA] CTD PMID:28159594 acrylamide increases expression ISO RGD:731551 6480464 Acrylamide results in increased expression of GCLM mRNA CTD PMID:32763439 acrylamide decreases expression ISO RGD:731551 6480464 Acrylamide results in decreased expression of GCLM mRNA CTD PMID:28159594 aflatoxin B1 decreases expression ISO RGD:735691 6480464 Aflatoxin B1 results in decreased expression of GCLM mRNA CTD PMID:19770486 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of GCLM mRNA CTD PMID:23630614 , PMID:25378103 AL 8810 multiple interactions ISO RGD:731551 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] CTD PMID:33486071 alachlor increases expression EXP 6480464 alachlor results in increased expression of GCLM protein CTD PMID:14563481 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of GCLM mRNA, Tretinoin results in decreased expression of GCLM protein CTD PMID:30267739 all-trans-retinoic acid decreases expression ISO RGD:731551 6480464 Tretinoin results in decreased expression of GCLM mRNA CTD PMID:33167477 alpha,alpha-trehalose multiple interactions EXP 6480464 Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLM protein] CTD PMID:29140578 alpha-hexylcinnamaldehyde increases expression ISO RGD:731551 6480464 hexyl cinnamic aldehyde results in increased expression of GCLM mRNA CTD PMID:20566472 alpha-Solamarine multiple interactions ISO RGD:735691 6480464 alpha-solamargine inhibits the reaction [Sevoflurane results in decreased expression of GCLM mRNA] CTD PMID:35350913 aminoguanidine multiple interactions ISO RGD:735691 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of GCLM mRNA] CTD PMID:12763045 amiodarone increases expression ISO RGD:731551 6480464 Amiodarone results in increased expression of GCLM mRNA CTD PMID:36586010 amlexanox multiple interactions ISO RGD:735691 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA CTD PMID:31697998 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of GCLM mRNA CTD PMID:16483693 ammonium hexachloroplatinate increases expression ISO RGD:731551 6480464 ammonium hexachloroplatinate results in increased expression of GCLM mRNA CTD PMID:24211530 ampicillin increases expression ISO RGD:731551 6480464 Ampicillin results in increased expression of GCLM mRNA CTD PMID:22609641 ampicillin decreases expression ISO RGD:731551 6480464 Ampicillin results in decreased expression of GCLM mRNA CTD PMID:21632981 andrographolide increases expression EXP 6480464 andrographolide results in increased expression of GCLM mRNA, andrographolide results in increased expression of GCLM protein CTD PMID:25110055 , PMID:29355602 andrographolide multiple interactions ISO RGD:731551 6480464 [andrographolide co-treated with TNF protein] results in increased expression of GCLM mRNA CTD PMID:35724838 andrographolide decreases expression ISO RGD:731551 6480464 andrographolide results in decreased expression of GCLM mRNA CTD PMID:35724838 andrographolide increases expression ISO RGD:735691 6480464 andrographolide results in increased expression of GCLM protein CTD PMID:29355602 andrographolide increases expression ISO RGD:731551 6480464 andrographolide results in increased expression of GCLM protein CTD PMID:29355602 andrographolide multiple interactions ISO RGD:735691 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA, andrographolide inhibits the reaction [Acetaminophen results in decreased expression of GCLM mRNA] CTD PMID:19737545 , PMID:29355602 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:731551 6480464 pyrazolanthrone inhibits the reaction [[Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA] more ... CTD PMID:25881548 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO RGD:731551 6480464 pyrazolanthrone results in decreased activity of GCLM protein CTD PMID:16972261 antimonite multiple interactions ISO RGD:731551 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA CTD PMID:32076005 antimycin A increases expression ISO RGD:731551 6480464 Antimycin A results in increased expression of GCLM mRNA CTD PMID:33512557 antirheumatic drug increases expression ISO RGD:731551 6480464 Antirheumatic Agents results in increased expression of GCLM mRNA CTD PMID:24449571 apigenin increases expression EXP 6480464 Apigenin results in increased expression of GCLM mRNA, Apigenin results in increased expression of GCLM protein CTD PMID:22864849 apigenin multiple interactions EXP 6480464 [Apigenin results in increased expression of GCLM mRNA] which results in decreased susceptibility to tert-Butylhydroperoxide CTD PMID:22864849 arachidonic acid increases expression ISO RGD:731551 6480464 Arachidonic Acid results in increased expression of GCLM mRNA CTD PMID:16704987 arachidonic acid increases expression EXP 6480464 Arachidonic Acid metabolite results in increased expression of GCLM mRNA CTD PMID:27012417 aristolochic acid A decreases expression ISO RGD:731551 6480464 aristolochic acid I results in decreased expression of GCLM mRNA CTD PMID:33212167 arotinoid acid multiple interactions ISO RGD:731551 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane increases expression ISO RGD:731551 6480464 Arsenic results in increased expression of GCLM mRNA, Arsenic results in increased expression of GCLM protein CTD PMID:18487201 more ... arsane multiple interactions ISO RGD:731551 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:32188015 more ... arsenic atom increases expression ISO RGD:731551 6480464 Arsenic results in increased expression of GCLM mRNA, Arsenic results in increased expression of GCLM protein CTD PMID:18487201 more ... arsenic atom multiple interactions ISO RGD:731551 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:32188015 more ... arsenite(3-) increases expression ISO RGD:731551 6480464 arsenite results in increased expression of GCLM mRNA CTD PMID:22476201 , PMID:25680285 arsenite(3-) multiple interactions ISO RGD:731551 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of GCLM mRNA more ... CTD PMID:22476201 more ... arsenite(3-) increases expression ISO RGD:735691 6480464 arsenite results in increased expression of GCLM mRNA, arsenite results in increased expression of GCLM protein CTD PMID:15894712 more ... arsenite(3-) increases stability ISO RGD:735691 6480464 arsenite results in increased stability of GCLM mRNA CTD PMID:19328227 arsenite(3-) multiple interactions ISO RGD:735691 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenite results in increased expression of GCLM mRNA] more ... CTD PMID:15894712 more ... arsenous acid increases expression ISO RGD:731551 6480464 Arsenic Trioxide results in increased expression of GCLM mRNA CTD PMID:15725085 more ... arsenous acid decreases expression ISO RGD:731551 6480464 Arsenic Trioxide results in decreased expression of GCLM protein CTD PMID:25341331 arsenous acid multiple interactions ISO RGD:731551 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:19350554 more ... artesunate decreases response to substance ISO RGD:731551 6480464 GCLM mRNA results in decreased susceptibility to artesunate CTD PMID:15796179 astilbin multiple interactions ISO RGD:731551 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] CTD PMID:29471006 atrazine increases expression ISO RGD:735691 6480464 Atrazine results in increased expression of GCLM mRNA CTD PMID:36216167 atrazine multiple interactions ISO RGD:735691 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA] CTD PMID:36216167 Augmentin increases expression ISO RGD:731551 6480464 Amoxicillin-Potassium Clavulanate Combination results in increased expression of GCLM mRNA CTD PMID:34767876 azathioprine increases expression ISO RGD:731551 6480464 Azathioprine results in increased expression of GCLM mRNA CTD PMID:18222062 more ... azoxystrobin increases expression ISO RGD:731551 6480464 azoxystrobin results in increased expression of GCLM mRNA CTD PMID:33512557 Bandrowski's base increases expression ISO RGD:731551 6480464 Bandrowski's base results in increased expression of GCLM mRNA CTD PMID:20566472 Bardoxolone methyl increases expression ISO RGD:731551 6480464 bardoxolone methyl results in increased expression of GCLM, bardoxolone methyl results in increased expression of GCLM mRNA CTD PMID:21723306 , PMID:34480604 Bardoxolone methyl decreases expression ISO RGD:731551 6480464 bardoxolone methyl results in decreased expression of GCLM mRNA CTD PMID:35724838 benfotiamine multiple interactions ISO RGD:735691 6480464 NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA], NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA] CTD PMID:29860433 benfotiamine increases expression ISO RGD:735691 6480464 benphothiamine metabolite results in increased expression of GCLM mRNA, benphothiamine results in increased expression of GCLM mRNA CTD PMID:29860433 benzalkonium chloride increases expression ISO RGD:731551 6480464 Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 benzene increases expression ISO RGD:731551 6480464 Benzene results in increased expression of GCLM mRNA CTD PMID:21843810 benzidine increases expression ISO RGD:731551 6480464 benzidine results in increased expression of GCLM mRNA CTD PMID:26198647 benzo[a]pyrene multiple interactions ISO RGD:735691 6480464 [arsenite co-treated with Benzo(a)pyrene] results in increased expression of GCLM mRNA more ... CTD PMID:15894712 more ... benzo[a]pyrene affects methylation ISO RGD:731551 6480464 Benzo(a)pyrene affects the methylation of GCLM promoter CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:731551 6480464 Benzo(a)pyrene results in increased expression of GCLM mRNA, Benzo(a)pyrene results in increased expression of GCLM protein CTD PMID:20064835 more ... benzo[a]pyrene increases response to substance ISO RGD:735691 6480464 GCLM gene mutant form results in increased susceptibility to Benzo(a)pyrene CTD PMID:23135907 , PMID:28279692 benzo[a]pyrene decreases response to substance ISO RGD:735691 6480464 GCLM gene mutant form results in decreased susceptibility to Benzo(a)pyrene CTD PMID:24291350 benzo[a]pyrene increases expression ISO RGD:735691 6480464 Benzo(a)pyrene results in increased expression of GCLM mRNA CTD PMID:15034205 more ... benzo[a]pyrene affects response to substance ISO RGD:735691 6480464 GCLM protein affects the susceptibility to Benzo(a)pyrene CTD PMID:22253057 benzo[a]pyrene decreases expression ISO RGD:735691 6480464 Benzo(a)pyrene results in decreased expression of GCLM mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:731551 6480464 7 more ... CTD PMID:19150397 benzoic acid increases expression ISO RGD:731551 6480464 Benzoic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 benzoquinones increases expression ISO RGD:735691 6480464 Benzoquinones analog results in increased expression of GCLM protein CTD PMID:21651925 benzylpenicillin increases expression ISO RGD:731551 6480464 Penicillin G results in increased expression of GCLM mRNA CTD PMID:22609641 berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of GCLM mRNA] CTD PMID:35121005 beta-naphthoflavone increases expression ISO RGD:731551 6480464 beta-Naphthoflavone results in increased expression of GCLM mRNA CTD PMID:19737606 , PMID:32858204 beta-naphthoflavone multiple interactions ISO RGD:735691 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA CTD PMID:19737545 beta-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 Betanin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735691 6480464 Diethylhexyl Phthalate results in increased expression of GCLM mRNA, Diethylhexyl Phthalate results in increased expression of GCLM protein CTD PMID:35818324 , PMID:35917956 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:735691 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] CTD PMID:35917956 bisdemethoxycurcumin increases expression ISO RGD:735691 6480464 bisdemethoxycurcumin results in increased expression of GCLM mRNA CTD PMID:17535857 bisdemethoxycurcumin increases expression ISO RGD:731551 6480464 bisdemethoxycurcumin results in increased expression of GCLM mRNA, bisdemethoxycurcumin results in increased expression of GCLM protein CTD PMID:19188863 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of GCLM mRNA CTD PMID:25181051 more ... bisphenol A affects expression ISO RGD:731551 6480464 bisphenol A affects the expression of GCLM mRNA CTD PMID:30903817 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GCLM gene CTD PMID:28505145 bisphenol A decreases expression ISO RGD:735691 6480464 bisphenol A results in decreased expression of GCLM mRNA CTD PMID:26063408 Bisphenol A diglycidyl ether increases expression ISO RGD:731551 6480464 2, 2-bis(4-glycidyloxyphenyl)propane results in increased expression of GCLM mRNA CTD PMID:27965148 Bisphenol A glycidylmethacrylate increases expression ISO RGD:731551 6480464 Bisphenol A-Glycidyl Methacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 bisphenol F increases expression ISO RGD:731551 6480464 bisphenol F results in increased expression of GCLM protein CTD PMID:34186270 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of GCLM mRNA CTD PMID:35121005 bortezomib multiple interactions EXP 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of GCLM mRNA] CTD PMID:35121005 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of GCLM mRNA CTD PMID:12628495 buta-1,3-diene increases expression ISO RGD:735691 6480464 1, 3-butadiene results in increased expression of GCLM mRNA CTD PMID:29038090 butan-1-ol multiple interactions ISO RGD:731551 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GCLM mRNA CTD PMID:29432896 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of GCLM mRNA CTD PMID:19167457 cadmium atom increases expression ISO RGD:731551 6480464 Cadmium results in increased expression of GCLM mRNA CTD PMID:21120746 more ... cadmium atom multiple interactions ISO RGD:731551 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA CTD PMID:35301059 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of GCLM mRNA CTD PMID:25388156 cadmium atom multiple interactions ISO RGD:735691 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA more ... CTD PMID:33398418 cadmium dichloride increases expression ISO RGD:735691 6480464 Cadmium Chloride results in increased expression of GCLM mRNA CTD PMID:20061341 cadmium dichloride multiple interactions ISO RGD:731551 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA CTD PMID:35301059 cadmium dichloride increases expression ISO RGD:731551 6480464 Cadmium Chloride results in increased expression of GCLM mRNA CTD PMID:25596134 cadmium dichloride multiple interactions ISO RGD:735691 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA more ... CTD PMID:26827822 , PMID:33398418 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GCLM mRNA CTD PMID:19010381 cannabidiol increases expression ISO RGD:735691 6480464 Cannabidiol results in increased expression of GCLM mRNA CTD PMID:21542829 cannabidiol increases expression ISO RGD:731551 6480464 Cannabidiol results in increased expression of GCLM mRNA CTD PMID:31518892 captan increases expression ISO RGD:735691 6480464 Captan results in increased expression of GCLM mRNA CTD PMID:31558096 carbamazepine affects expression ISO RGD:731551 6480464 Carbamazepine affects the expression of GCLM mRNA CTD PMID:24752500 , PMID:25979313 carbaryl increases expression ISO RGD:731551 6480464 Carbaryl results in increased expression of GCLM mRNA CTD PMID:27829164 carbon nanotube increases expression ISO RGD:731551 6480464 Nanotubes, Carbon results in increased expression of GCLM protein CTD PMID:23026733 carnosic acid multiple interactions ISO RGD:731551 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein] more ... CTD PMID:25446857 more ... carnosic acid multiple interactions EXP 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] CTD PMID:25446857 carnosic acid increases expression ISO RGD:731551 6480464 salvin results in increased expression of GCLM protein CTD PMID:26577515 , PMID:26686574 Carnosol increases expression ISO RGD:731551 6480464 carnosol results in increased expression of GCLM mRNA CTD PMID:20116392 celastrol increases expression ISO RGD:731551 6480464 celastrol results in increased expression of GCLM mRNA CTD PMID:17010675 celastrol multiple interactions EXP 6480464 celastrol inhibits the reaction [Doxorubicin results in decreased expression of GCLM mRNA] CTD PMID:30588110 ceric oxide decreases expression EXP 6480464 ceric oxide results in decreased expression of GCLM mRNA CTD PMID:29463257 cerium trichloride decreases expression ISO RGD:731551 6480464 cerous chloride results in decreased expression of GCLM mRNA CTD PMID:28954213 chalcone increases expression ISO RGD:731551 6480464 Chalcone analog results in increased expression of GCLM mRNA, Chalcone analog results in increased expression of GCLM protein CTD PMID:31299238 chenodeoxycholic acid multiple interactions ISO RGD:731551 6480464 [Chenodeoxycholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione more ... CTD PMID:17724089 , PMID:33819548 chenodeoxycholic acid increases expression ISO RGD:731551 6480464 Chenodeoxycholic Acid results in increased expression of GCLM protein CTD PMID:17724089 CHIR 99021 multiple interactions ISO RGD:731551 6480464 [4-(2-(5 more ... CTD PMID:34480604 chlorambucil multiple interactions ISO RGD:731551 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Chlorambucil CTD PMID:10900222 chloroacetaldehyde increases expression ISO RGD:731551 6480464 chloroacetaldehyde results in increased expression of GCLM mRNA CTD PMID:25596134 chlorogenic acid increases expression ISO RGD:731551 6480464 Chlorogenic Acid results in increased expression of GCLM mRNA CTD PMID:29136249 chloropicrin increases expression ISO RGD:731551 6480464 chloropicrin results in increased expression of GCLM mRNA CTD PMID:24211530 chloroprene increases expression ISO RGD:735691 6480464 Chloroprene results in increased expression of GCLM mRNA CTD PMID:23125180 chlorpyrifos multiple interactions ISO RGD:735691 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 chlorpyrifos decreases expression ISO RGD:735691 6480464 Chlorpyrifos results in decreased expression of GCLM mRNA CTD PMID:32955216 choline multiple interactions ISO RGD:735691 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 chromium(6+) multiple interactions ISO RGD:735691 6480464 [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of GCLM mRNA CTD PMID:25820237 chrysin multiple interactions EXP 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] more ... CTD PMID:22864849 , PMID:33121995 chrysin increases expression EXP 6480464 chrysin results in increased expression of GCLM mRNA, chrysin results in increased expression of GCLM protein CTD PMID:22864849 cidofovir anhydrous increases expression ISO RGD:731551 6480464 Cidofovir results in increased expression of GCLM mRNA CTD PMID:25596134 cinnamyl alcohol increases expression ISO RGD:731551 6480464 cinnamyl alcohol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... cisplatin multiple interactions ISO RGD:731551 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] more ... CTD PMID:17628013 more ... cisplatin increases expression ISO RGD:731551 6480464 Cisplatin results in increased expression of GCLM mRNA CTD PMID:25450742 more ... cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of GCLM mRNA CTD PMID:33661552 cisplatin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:33661552 citraconic acid increases expression EXP 6480464 citraconic acid results in increased expression of GCLM protein CTD PMID:27277809 citraconic acid increases expression ISO RGD:735691 6480464 citraconic acid results in increased expression of GCLM mRNA CTD PMID:27277809 citral increases expression ISO RGD:731551 6480464 citral results in increased expression of GCLM mRNA CTD PMID:27965148 clavulanic acid increases expression ISO RGD:731551 6480464 Clavulanic Acid results in increased expression of GCLM mRNA CTD PMID:34767876 Clivoline decreases expression ISO RGD:731551 6480464 clivorine results in decreased expression of GCLM mRNA CTD PMID:25881548 Clivoline multiple interactions ISO RGD:731551 6480464 pyrazolanthrone inhibits the reaction [Quercetin inhibits the reaction [clivorine results in decreased expression of GCLM mRNA]], Quercetin inhibits the reaction [clivorine results in decreased expression of GCLM mRNA] CTD PMID:25881548 clodronic acid increases expression ISO RGD:731551 6480464 Clodronic Acid results in increased expression of GCLM mRNA CTD PMID:25596134 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of GCLM protein CTD PMID:16470657 cobalt atom multiple interactions ISO RGD:731551 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of GCLM mRNA CTD PMID:23052192 cobalt dichloride increases expression ISO RGD:731551 6480464 cobaltous chloride results in increased expression of GCLM mRNA CTD PMID:19320972 more ... cobalt dichloride multiple interactions ISO RGD:731551 6480464 KEAP1 protein inhibits the reaction [cobaltous chloride results in increased expression of GCLM mRNA], NFE2L2 protein promotes the reaction [cobaltous chloride results in increased expression of GCLM mRNA] CTD PMID:29966676 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GCLM mRNA, cobaltous chloride results in increased expression of GCLM protein CTD PMID:24386269 cocaine affects expression EXP 6480464 Cocaine affects the expression of GCLM mRNA CTD PMID:20187946 cocaine increases expression ISO RGD:735691 6480464 Cocaine results in increased expression of GCLM mRNA CTD PMID:30393195 cocaine multiple interactions ISO RGD:735691 6480464 PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA], rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA] CTD PMID:30393195 coniferyl aldehyde increases expression ISO RGD:731551 6480464 coniferaldehyde results in increased expression of GCLM mRNA CTD PMID:26275128 copper atom increases expression ISO RGD:735691 6480464 Copper analog results in increased expression of GCLM protein, Copper results in increased expression of GCLM protein CTD PMID:23882024 copper atom multiple interactions ISO RGD:731551 6480464 [Chelating Agents binds to Copper] which results in increased expression of GCLM mRNA more ... CTD PMID:20971185 more ... copper(0) increases expression ISO RGD:735691 6480464 Copper analog results in increased expression of GCLM protein, Copper results in increased expression of GCLM protein CTD PMID:23882024 copper(0) multiple interactions ISO RGD:731551 6480464 [Chelating Agents binds to Copper] which results in increased expression of GCLM mRNA more ... CTD PMID:20971185 more ... copper(II) chloride increases expression ISO RGD:731551 6480464 cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630 , PMID:24343273 copper(II) sulfate increases expression ISO RGD:731551 6480464 Copper Sulfate results in increased expression of GCLM mRNA CTD PMID:19549813 cortisol multiple interactions ISO RGD:731551 6480464 [4-(2-(5 more ... CTD PMID:34480604 coumarin increases expression EXP 6480464 coumarin results in increased expression of GCLM mRNA CTD PMID:18480146 coumestrol multiple interactions ISO RGD:731551 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of GCLM mRNA CTD PMID:19167446 crocidolite asbestos multiple interactions ISO RGD:735691 6480464 [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos more ... CTD PMID:15520183 crocidolite asbestos increases expression ISO RGD:735691 6480464 Asbestos, Crocidolite results in increased expression of GCLM mRNA CTD PMID:15520183 CU-O LINKAGE increases expression ISO RGD:735691 6480464 cupric oxide analog results in increased expression of GCLM protein CTD PMID:23882024 CU-O LINKAGE increases expression ISO RGD:731551 6480464 cupric oxide results in increased expression of GCLM mRNA CTD PMID:24343273 cumene hydroperoxide increases expression ISO RGD:735691 6480464 cumene hydroperoxide results in increased expression of GCLM mRNA CTD PMID:30547568 curcumin multiple interactions EXP 6480464 Curcumin results in increased activity of [GCLC protein binds to GCLM protein] CTD PMID:17602960 curcumin multiple interactions ISO RGD:735691 6480464 Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLM mRNA] CTD PMID:34272803 curcumin increases expression ISO RGD:731551 6480464 Curcumin analog results in increased expression of GCLM mRNA more ... CTD PMID:17198877 more ... curcumin multiple interactions ISO RGD:731551 6480464 NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA], NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA] CTD PMID:23954767 curcumin increases expression ISO RGD:735691 6480464 Curcumin results in increased expression of GCLM mRNA CTD PMID:17535857 more ... curcumin increases expression EXP 6480464 Curcumin results in increased expression of GCLM mRNA, Curcumin results in increased expression of GCLM protein CTD PMID:17602960 , PMID:18332871 cycloheximide multiple interactions ISO RGD:735691 6480464 Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]] more ... CTD PMID:19328227 cyclosporin A increases expression ISO RGD:731551 6480464 Cyclosporine results in increased expression of GCLM mRNA CTD PMID:20106945 more ... cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of GCLM mRNA CTD PMID:11589784 , PMID:25596134 DDT increases expression ISO RGD:731551 6480464 DDT results in increased expression of GCLM mRNA CTD PMID:26198647 deguelin increases expression ISO RGD:731551 6480464 deguelin results in increased expression of GCLM mRNA CTD PMID:33512557 delta-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 demethoxycurcumin increases expression ISO RGD:735691 6480464 demethoxycurcumin results in increased expression of GCLM mRNA CTD PMID:17535857 demethoxycurcumin increases expression ISO RGD:731551 6480464 demethoxycurcumin results in increased expression of GCLM mRNA, demethoxycurcumin results in increased expression of GCLM protein CTD PMID:19188863 , PMID:23386263 deoxycholic acid multiple interactions ISO RGD:731551 6480464 [Deoxycholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA more ... CTD PMID:17724089 , PMID:33819548 deoxynivalenol increases expression ISO RGD:735691 6480464 deoxynivalenol results in increased expression of GCLM mRNA CTD PMID:34400200 dexamethasone multiple interactions ISO RGD:735691 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 dextran sulfate multiple interactions ISO RGD:735691 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLM mRNA CTD PMID:29950665 dextromethorphan multiple interactions ISO RGD:735691 6480464 PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLM mRNA] more ... CTD PMID:34740715 dextromethorphan affects expression ISO RGD:735691 6480464 Dextromethorphan affects the expression of GCLM mRNA CTD PMID:34740715 diallyl disulfide multiple interactions ISO RGD:735691 6480464 diallyl disulfide promotes the reaction [lipopolysaccharide more ... CTD PMID:34896185 diallyl disulfide increases expression ISO RGD:735691 6480464 diallyl disulfide results in increased expression of GCLM mRNA CTD PMID:34896185 diarsenic trioxide increases expression ISO RGD:731551 6480464 Arsenic Trioxide results in increased expression of GCLM mRNA CTD PMID:15725085 more ... diarsenic trioxide decreases expression ISO RGD:731551 6480464 Arsenic Trioxide results in decreased expression of GCLM protein CTD PMID:25341331 diarsenic trioxide multiple interactions ISO RGD:731551 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:19350554 more ... diazinon increases expression ISO RGD:731551 6480464 Diazinon results in increased expression of GCLM mRNA CTD PMID:26198647 dibutyl phthalate increases expression ISO RGD:735691 6480464 Dibutyl Phthalate results in increased expression of GCLM mRNA CTD PMID:21266533 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA CTD PMID:18636392 diclofenac affects expression ISO RGD:731551 6480464 Diclofenac affects the expression of GCLM mRNA CTD PMID:24752500 diethyl malate multiple interactions ISO RGD:735691 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 diethyl malate affects expression ISO RGD:735691 6480464 diethyl malate affects the expression of GCLM mRNA CTD PMID:24814887 diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of GCLM mRNA, diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 more ... diethyl maleate increases expression ISO RGD:731551 6480464 diethyl maleate results in increased expression of GCLM mRNA CTD PMID:33545341 , PMID:34480604 diethyl maleate increases expression ISO RGD:735691 6480464 diethyl maleate results in increased expression of GCLM mRNA CTD PMID:25270620 dihydrogen multiple interactions ISO RGD:735691 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 dimethyl fumarate multiple interactions ISO RGD:735691 6480464 NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA] CTD PMID:27277809 dimethyl fumarate increases expression EXP 6480464 Dimethyl Fumarate results in increased expression of GCLM protein CTD PMID:27277809 dimethyl fumarate increases expression ISO RGD:735691 6480464 Dimethyl Fumarate results in increased expression of GCLM mRNA CTD PMID:27277809 dimethylarsinic acid multiple interactions ISO RGD:731551 6480464 [Cacodylic Acid results in increased abundance of Arsenic] which results in increased expression of GCLM protein CTD PMID:33434570 dinoseb increases expression ISO RGD:735691 6480464 dinoseb results in increased expression of GCLM mRNA CTD PMID:30547568 dioxygen decreases expression ISO RGD:731551 6480464 Oxygen deficiency results in decreased expression of GCLM mRNA CTD PMID:25596134 more ... dioxygen increases expression ISO RGD:731551 6480464 Oxygen deficiency results in increased expression of GCLM mRNA CTD PMID:29966676 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO RGD:731551 6480464 Antimony Potassium Tartrate results in increased expression of GCLM mRNA CTD PMID:28713220 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO RGD:731551 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA CTD PMID:32076005 diprotium multiple interactions ISO RGD:735691 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 diquat increases expression ISO RGD:731551 6480464 Diquat results in increased expression of GCLM mRNA CTD PMID:21172416 diquat increases expression ISO RGD:735691 6480464 Diquat results in increased expression of GCLM mRNA CTD PMID:16962985 , PMID:20826540 disulfiram increases expression ISO RGD:731551 6480464 Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 dodecan-1-ol increases expression ISO RGD:731551 6480464 Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 domoic acid decreases response to substance ISO RGD:735691 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2 more ... CTD PMID:19200344 , PMID:23315585 domoic acid affects response to substance ISO RGD:735691 6480464 GCLM affects the susceptibility to domoic acid CTD PMID:17804861 domoic acid increases expression ISO RGD:735691 6480464 domoic acid results in increased expression of GCLM mRNA, domoic acid results in increased expression of GCLM protein CTD PMID:23315585 dopamine multiple interactions ISO RGD:735691 6480464 [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine CTD PMID:23704229 dorsomorphin multiple interactions ISO RGD:735691 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA CTD PMID:31697998 dorsomorphin multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:731551 6480464 [GCLC protein co-treated with GCLM protein] promotes the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:10900222 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of GCLM mRNA CTD PMID:30588110 doxorubicin multiple interactions EXP 6480464 celastrol inhibits the reaction [Doxorubicin results in decreased expression of GCLM mRNA] CTD PMID:30588110 doxorubicin increases metabolic processing ISO RGD:735691 6480464 GCLM gene mutant form results in increased metabolism of Doxorubicin CTD PMID:25446851 doxorubicin multiple interactions ISO RGD:735691 6480464 [GCLM gene mutant form results in increased metabolism of Doxorubicin] which results in increased abundance of adriamycinol, ABCC1 gene mutant form promotes the reaction [Doxorubicin results in increased expression of GCLM protein] CTD PMID:25446851 , PMID:26822305 doxorubicin increases expression ISO RGD:735691 6480464 Doxorubicin results in increased expression of GCLM protein CTD PMID:26822305 elesclomol multiple interactions ISO RGD:731551 6480464 Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] CTD PMID:18723479 elesclomol increases expression ISO RGD:731551 6480464 elesclomol results in increased expression of GCLM mRNA CTD PMID:18723479 emodin increases expression EXP 6480464 Emodin results in increased expression of GCLM mRNA CTD PMID:34971761 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of GCLM mRNA CTD PMID:29391264 entinostat multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 entinostat increases expression ISO RGD:731551 6480464 entinostat results in increased expression of GCLM mRNA CTD PMID:26272509 enzyme inhibitor multiple interactions ISO RGD:731551 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GCLM protein CTD PMID:23301498 epichlorohydrin increases expression ISO RGD:731551 6480464 Epichlorohydrin results in increased expression of GCLM mRNA CTD PMID:24211530 Epomediol multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with epomediol] results in increased activity of GCLM protein CTD PMID:12071332 erastin increases expression EXP 6480464 erastin results in increased expression of GCLM protein CTD PMID:32937103 erastin multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [erastin results in increased expression of GCLM protein] CTD PMID:32937103 erdosteine increases expression ISO RGD:735691 6480464 erdosteine results in increased expression of GCLM protein CTD PMID:26193055 etacrynic acid multiple interactions ISO RGD:731551 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Ethacrynic Acid CTD PMID:10900222 ethanol affects splicing ISO RGD:735691 6480464 Ethanol affects the splicing of GCLM mRNA CTD PMID:30319688 ethionamide multiple interactions ISO RGD:731551 6480464 Ethionamide inhibits the reaction [arsenic trioxide results in increased expression of GCLM mRNA] CTD PMID:26708503 ethylene glycol dimethacrylate increases expression ISO RGD:731551 6480464 ethylene dimethacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 etoposide multiple interactions ISO RGD:731551 6480464 [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide], [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 eugenol increases expression ISO RGD:731551 6480464 Eugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... fenofibrate increases expression ISO RGD:731551 6480464 Fenofibrate results in increased expression of GCLM mRNA CTD PMID:25596134 fenpyroximate increases expression ISO RGD:731551 6480464 fenpyroximate results in increased expression of GCLM mRNA CTD PMID:33512557 fluprostenol multiple interactions ISO RGD:731551 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] more ... CTD PMID:33486071 flutamide increases expression EXP 6480464 Flutamide results in increased expression of GCLM mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:735691 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 folpet increases expression ISO RGD:735691 6480464 folpet results in increased expression of GCLM mRNA CTD PMID:31558096 formaldehyde decreases expression ISO RGD:731551 6480464 Formaldehyde results in decreased expression of GCLM mRNA CTD PMID:23649840 formononetin multiple interactions ISO RGD:731551 6480464 [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein more ... CTD PMID:34077701 fumonisin B1 decreases expression ISO RGD:735691 6480464 fumonisin B1 results in decreased expression of GCLM mRNA CTD PMID:35697133 furosemide multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA, [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 gamma-hexachlorocyclohexane increases expression ISO RGD:731551 6480464 Hexachlorocyclohexane results in increased expression of GCLM mRNA CTD PMID:26198647 gamma-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 gedunin increases expression ISO RGD:731551 6480464 gedunin results in increased expression of GCLM mRNA CTD PMID:17010675 genistein decreases expression EXP 6480464 Genistein results in decreased expression of GCLM mRNA CTD PMID:12075121 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of GCLM mRNA CTD PMID:33387578 geranial increases expression ISO RGD:731551 6480464 citral results in increased expression of GCLM mRNA CTD PMID:27965148 ginsenoside Rg1 multiple interactions ISO RGD:735691 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein] CTD PMID:29964319 ginsenoside Rg1 increases expression ISO RGD:735691 6480464 ginsenoside Rg1 results in increased expression of GCLM protein CTD PMID:29964319 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of GCLM mRNA CTD PMID:24136188 glutathione multiple interactions ISO RGD:731551 6480464 [Chenodeoxycholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione more ... CTD PMID:12975258 , PMID:17724089 glutathione increases abundance ISO RGD:731551 6480464 GCLM gene SNP results in increased abundance of Glutathione CTD PMID:32715377 glutathione increases chemical synthesis ISO RGD:735691 6480464 GCLM protein results in increased chemical synthesis of Glutathione CTD PMID:22253057 , PMID:23135907 glutathione affects response to substance ISO RGD:735691 6480464 GCLM protein affects the susceptibility to Glutathione CTD PMID:17584759 glutathione decreases abundance ISO RGD:735691 6480464 GCLM gene mutant form results in decreased abundance of Glutathione, GCLM protein mutant form results in decreased abundance of Glutathione CTD PMID:20417186 more ... glutathione increases expression EXP 6480464 Glutathione deficiency results in increased expression of GCLM mRNA CTD PMID:15345336 , PMID:20621112 glutathione affects metabolic processing ISO RGD:735691 6480464 GCLM protein affects the metabolism of Glutathione CTD PMID:22253057 glutathione multiple interactions ISO RGD:735691 6480464 [GCLM gene mutant form results in decreased abundance of Glutathione] which results in decreased susceptibility to Benzo(a)pyrene more ... CTD PMID:20159942 more ... Glutathione ethyl ester multiple interactions ISO RGD:735691 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 glycochenodeoxycholic acid multiple interactions ISO RGD:731551 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:731551 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:731551 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 glyoxal increases expression ISO RGD:731551 6480464 Glyoxal results in increased expression of GCLM mRNA CTD PMID:27965148 guggulsterone increases expression ISO RGD:731551 6480464 pregna-4 more ... CTD PMID:22851183 guggulsterone increases expression ISO RGD:735691 6480464 pregna-4 more ... CTD PMID:22851183 GW 4064 increases expression ISO RGD:735691 6480464 GW 4064 results in increased expression of GCLM mRNA CTD PMID:26655953 hemin increases expression ISO RGD:731551 6480464 Hemin results in increased expression of GCLM mRNA, Hemin results in increased expression of GCLM protein CTD PMID:33434570 hemin multiple interactions ISO RGD:731551 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA, [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein CTD PMID:33434570 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of GCLM mRNA CTD PMID:15159207 hexamethylene diisocyanate increases expression ISO RGD:731551 6480464 1, 6-hexamethylene diisocyanate results in increased expression of GCLM mRNA CTD PMID:24211530 hexane increases expression ISO RGD:731551 6480464 n-hexane results in increased expression of GCLM mRNA CTD PMID:20566472 homoeriodictyol increases expression ISO RGD:731551 6480464 homoeriodictyol results in increased expression of GCLM mRNA CTD PMID:29902531 hydrogen chloride multiple interactions ISO RGD:735691 6480464 NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLM mRNA] CTD PMID:29618784 hydrogen chloride increases expression ISO RGD:735691 6480464 Hydrochloric Acid results in increased expression of GCLM mRNA CTD PMID:29618784 hydrogen peroxide decreases expression ISO RGD:731551 6480464 Hydrogen Peroxide results in decreased expression of GCLM mRNA CTD PMID:18951874 , PMID:29274434 hydrogen peroxide multiple interactions ISO RGD:731551 6480464 [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein more ... CTD PMID:29274434 more ... hydrogen peroxide increases expression ISO RGD:731551 6480464 Hydrogen Peroxide results in increased expression of GCLM mRNA, Hydrogen Peroxide results in increased expression of GCLM protein CTD PMID:12414654 more ... hydrogen peroxide decreases response to substance ISO RGD:735691 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to Hydrogen Peroxide CTD PMID:23315585 hydroquinone increases expression ISO RGD:731551 6480464 hydroquinone results in increased expression of GCLM mRNA, hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 , PMID:31256213 hydroquinone increases expression ISO RGD:735691 6480464 hydroquinone results in increased expression of GCLM mRNA, hydroquinone results in increased expression of GCLM protein CTD PMID:30547568 hypochlorous acid increases expression ISO RGD:731551 6480464 Hypochlorous Acid results in increased expression of GCLM mRNA CTD PMID:18156441 hypochlorous acid increases expression ISO RGD:735691 6480464 Hypochlorous Acid results in increased expression of GCLM mRNA CTD PMID:19376150 ibuprofen increases expression ISO RGD:731551 6480464 Ibuprofen results in increased expression of GCLM mRNA CTD PMID:11909699 , PMID:25596134 ifosfamide increases expression ISO RGD:731551 6480464 Ifosfamide results in increased expression of GCLM mRNA CTD PMID:25596134 indometacin increases expression ISO RGD:731551 6480464 Indomethacin results in increased expression of GCLM mRNA CTD PMID:11909699 indometacin multiple interactions ISO RGD:735691 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 iodixanol multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA CTD PMID:29860548 iohexol multiple interactions EXP 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 iron atom multiple interactions ISO RGD:731551 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 iron atom decreases expression ISO RGD:731551 6480464 Iron results in decreased expression of GCLM mRNA CTD PMID:19073151 iron(0) multiple interactions ISO RGD:731551 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 iron(0) decreases expression ISO RGD:731551 6480464 Iron results in decreased expression of GCLM mRNA CTD PMID:19073151 iron(III) citrate increases expression ISO RGD:731551 6480464 ferric citrate results in increased expression of GCLM mRNA CTD PMID:29959986 isoeugenol increases expression ISO RGD:731551 6480464 isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... isoflavones increases expression ISO RGD:731551 6480464 Isoflavones results in increased expression of GCLM mRNA CTD PMID:17374662 isoniazide increases expression ISO RGD:735691 6480464 Isoniazid results in increased expression of GCLM mRNA CTD PMID:33771660 isoniazide multiple interactions EXP 6480464 chrysin inhibits the reaction [Isoniazid results in increased expression of GCLM mRNA] CTD PMID:33121995 isoniazide increases expression EXP 6480464 Isoniazid results in increased expression of GCLM mRNA CTD PMID:33121995 isoniazide decreases expression ISO RGD:731551 6480464 Isoniazid results in decreased expression of GCLM mRNA CTD PMID:30008028 isoprenaline increases expression ISO RGD:735691 6480464 Isoproterenol results in increased expression of GCLM mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA CTD PMID:30303030 isoprenaline decreases expression ISO RGD:735691 6480464 Isoproterenol results in decreased expression of GCLM mRNA CTD PMID:21335049 isotretinoin decreases expression ISO RGD:731551 6480464 Isotretinoin results in decreased expression of GCLM mRNA CTD PMID:20436886 ivermectin decreases expression ISO RGD:731551 6480464 Ivermectin results in decreased expression of GCLM protein CTD PMID:32959892 ketoprofen increases expression ISO RGD:731551 6480464 Ketoprofen results in increased expression of GCLM mRNA CTD PMID:11909699 L-ascorbic acid multiple interactions ISO RGD:731551 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:731551 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 L-methionine multiple interactions ISO RGD:735691 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 lead diacetate increases expression ISO RGD:735691 6480464 lead acetate results in increased expression of GCLM mRNA CTD PMID:25270620 lead diacetate multiple interactions ISO RGD:731551 6480464 NFE2L2 mutant form inhibits the reaction [lead acetate results in increased expression of GCLM mRNA] CTD PMID:26498409 lead diacetate increases expression ISO RGD:731551 6480464 lead acetate results in increased expression of GCLM mRNA CTD PMID:26498409 lead(0) affects abundance ISO RGD:731551 6480464 GCLM gene polymorphism affects the abundance of Lead CTD PMID:25728017 lead(2+) affects abundance ISO RGD:731551 6480464 GCLM gene polymorphism affects the abundance of Lead CTD PMID:25728017 limonene increases expression ISO RGD:731551 6480464 limonene results in increased expression of GCLM mRNA CTD PMID:27965148 linoleic acid increases expression ISO RGD:731551 6480464 Linoleic Acid metabolite results in increased expression of GCLM mRNA CTD PMID:26879219 lipoic acid increases expression ISO RGD:731551 6480464 Thioctic Acid results in increased expression of GCLM mRNA CTD PMID:16249512 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA], Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 lipopolysaccharide increases expression ISO RGD:735691 6480464 Lipopolysaccharides results in increased expression of GCLM mRNA CTD PMID:19339665 lipopolysaccharide multiple interactions ISO RGD:731551 6480464 [S-(1 more ... CTD PMID:35811015 lipopolysaccharide multiple interactions ISO RGD:735691 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA] more ... CTD PMID:19339665 more ... lipopolysaccharide affects expression ISO RGD:735691 6480464 Lipopolysaccharides affects the expression of GCLM mRNA CTD PMID:22169119 liquiritigenin increases expression EXP 6480464 liquiritigenin results in increased expression of GCLM protein CTD PMID:29908794 liquiritigenin multiple interactions EXP 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 liquiritin multiple interactions EXP 6480464 liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 liquiritin increases expression EXP 6480464 liquiritin results in increased expression of GCLM protein CTD PMID:29908794 lithocholic acid affects expression ISO RGD:731551 6480464 Lithocholic Acid affects the expression of GCLM mRNA, Lithocholic Acid affects the expression of GCLM protein CTD PMID:20146260 lithocholic acid decreases expression ISO RGD:735691 6480464 Lithocholic Acid results in decreased expression of GCLM mRNA CTD PMID:29794447 lithocholic acid multiple interactions ISO RGD:735691 6480464 [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA, Vardenafil Dihydrochloride inhibits the reaction [Lithocholic Acid results in decreased expression of GCLM mRNA] CTD PMID:17724089 , PMID:29794447 lithocholic acid increases expression ISO RGD:731551 6480464 Lithocholic Acid results in increased expression of GCLM protein CTD PMID:17724089 lithocholic acid multiple interactions ISO RGD:731551 6480464 [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA more ... CTD PMID:17724089 luteolin increases expression EXP 6480464 Luteolin results in increased expression of GCLM mRNA, Luteolin results in increased expression of GCLM protein CTD PMID:22864849 LY294002 multiple interactions ISO RGD:731551 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GCLM mRNA] CTD PMID:19073151 more ... LY294002 multiple interactions ISO RGD:735691 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]] CTD PMID:25895139 LY294002 decreases activity ISO RGD:731551 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of GCLM protein CTD PMID:16972261 LY294002 decreases expression ISO RGD:731551 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of GCLM mRNA CTD PMID:19073151 lycopene increases expression ISO RGD:735691 6480464 Lycopene results in increased expression of GCLM protein CTD PMID:36216167 lycopene multiple interactions ISO RGD:735691 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA], Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] CTD PMID:35917956 , PMID:36216167 malonaldehyde affects abundance ISO RGD:731551 6480464 GCLM gene polymorphism affects the abundance of Malondialdehyde CTD PMID:25728017 melatonin multiple interactions ISO RGD:735691 6480464 4-phenyl-2-propionamidotetraline inhibits the reaction [Melatonin inhibits the reaction [KL mutant form results in decreased expression of GCLM mRNA]] more ... CTD PMID:25550330 menadione increases expression ISO RGD:735691 6480464 Vitamin K 3 results in increased expression of GCLM mRNA CTD PMID:25270620 menadione increases expression ISO RGD:731551 6480464 Vitamin K 3 results in increased expression of GCLM mRNA CTD PMID:12414654 , PMID:23410634 mercaptopurine increases expression ISO RGD:731551 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 mercury atom decreases expression ISO RGD:731551 6480464 Mercury results in decreased expression of GCLM mRNA CTD PMID:19937285 mercury atom affects metabolic processing ISO RGD:731551 6480464 GCLM polymorphism affects the metabolism of Mercury CTD PMID:16961004 mercury atom affects abundance ISO RGD:731551 6480464 GCLM gene polymorphism affects the abundance of Mercury, GCLM protein affects the abundance of Mercury CTD PMID:18560528 , PMID:21925580 mercury dibromide increases expression ISO RGD:731551 6480464 mercuric bromide results in increased expression of GCLM mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 mercury dichloride increases expression ISO RGD:735691 6480464 Mercuric Chloride results in increased expression of GCLM mRNA CTD PMID:24039982 mercury dichloride multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 mercury dichloride multiple interactions ISO RGD:735691 6480464 ABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA] CTD PMID:24039982 mercury(0) decreases expression ISO RGD:731551 6480464 Mercury results in decreased expression of GCLM mRNA CTD PMID:19937285 mercury(0) affects metabolic processing ISO RGD:731551 6480464 GCLM polymorphism affects the metabolism of Mercury CTD PMID:16961004 mercury(0) affects abundance ISO RGD:731551 6480464 GCLM gene polymorphism affects the abundance of Mercury, GCLM protein affects the abundance of Mercury CTD PMID:18560528 , PMID:21925580 mesalamine multiple interactions ISO RGD:731551 6480464 Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 metam multiple interactions ISO RGD:735691 6480464 methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA] CTD PMID:19339665 metformin decreases expression EXP 6480464 Metformin results in decreased expression of GCLM mRNA CTD PMID:25596134 metformin decreases expression ISO RGD:731551 6480464 Metformin results in decreased expression of GCLM mRNA CTD PMID:33838154 metformin increases expression ISO RGD:731551 6480464 Metformin results in increased expression of GCLM mRNA CTD PMID:25596134 methidathion decreases expression ISO RGD:735691 6480464 methidathion results in decreased expression of GCLM mRNA CTD PMID:34813904 methyl methacrylate increases expression ISO RGD:735691 6480464 Methylmethacrylate results in increased expression of GCLM mRNA CTD PMID:16916219 methyl methanesulfonate increases expression ISO RGD:731551 6480464 Methyl Methanesulfonate results in increased expression of GCLM mRNA CTD PMID:23649840 methyl salicylate increases expression ISO RGD:731551 6480464 methyl salicylate results in increased expression of GCLM mRNA CTD PMID:20566472 methylene blue multiple interactions ISO RGD:735691 6480464 [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLM mRNA CTD PMID:24556215 methylisothiazolinone increases expression ISO RGD:731551 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of GCLM mRNA CTD PMID:30806763 methylmercury chloride increases expression ISO RGD:735691 6480464 methylmercuric chloride results in increased expression of GCLM mRNA CTD PMID:20061341 methylmercury chloride multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA], Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of GCLM mRNA, methylmercuric chloride results in increased expression of GCLM protein CTD PMID:32061141 methylmercury chloride multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 methylmercury chloride increases expression ISO RGD:731551 6480464 methylmercuric chloride results in increased expression of GCLM mRNA CTD PMID:23179753 more ... metronidazole multiple interactions ISO RGD:735691 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 mifepristone increases expression ISO RGD:735691 6480464 Mifepristone results in increased expression of GCLM protein CTD PMID:16840778 mifepristone multiple interactions ISO RGD:735691 6480464 Acetaminophen promotes the reaction [Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]], Mifepristone results in increased activity of [GCLC protein binds to GCLM protein] CTD PMID:16840778 monascin multiple interactions ISO RGD:731551 6480464 monascin inhibits the reaction [S100B protein results in decreased expression of GCLM mRNA], NFE2L2 mutant form inhibits the reaction [monascin inhibits the reaction [S100B protein results in decreased expression of GCLM mRNA]] CTD PMID:23331247 monocrotaline multiple interactions EXP 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA], liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 monocrotaline decreases expression EXP 6480464 Monocrotaline results in decreased expression of GCLM mRNA CTD PMID:29908794 motexafin gadolinium multiple interactions ISO RGD:731551 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA CTD PMID:16357179 motexafin gadolinium increases expression ISO RGD:731551 6480464 motexafin gadolinium results in increased expression of GCLM mRNA CTD PMID:16357179 N-acetyl-L-cysteine multiple interactions ISO RGD:731551 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA], Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] CTD PMID:18723479 , PMID:19350554 N-acetyl-L-cysteine affects response to substance ISO RGD:735691 6480464 GCLM protein affects the susceptibility to Acetylcysteine CTD PMID:17584759 N-acetyl-L-cysteine multiple interactions ISO RGD:735691 6480464 Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLM mRNA] CTD PMID:19328227 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:735691 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA CTD PMID:20061341 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:731551 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA, [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein CTD PMID:33434570 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:731551 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA, benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM protein CTD PMID:33434570 N-methyl-4-phenylpyridinium decreases expression ISO RGD:735691 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of GCLM protein CTD PMID:26558463 N-nitrosodiethylamine multiple interactions EXP 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of GCLM protein CTD PMID:19716841 N-tosyl-L-phenylalanyl chloromethyl ketone increases expression ISO RGD:731551 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLM mRNA CTD PMID:22851183 N-tosyl-L-phenylalanyl chloromethyl ketone increases expression ISO RGD:735691 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLM mRNA CTD PMID:22851183 naphthalene decreases expression ISO RGD:735691 6480464 naphthalene results in decreased expression of GCLM mRNA CTD PMID:31020322 naproxen increases expression ISO RGD:731551 6480464 Naproxen results in increased expression of GCLM mRNA CTD PMID:11909699 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of GCLM mRNA CTD PMID:24136188 neoastilbin multiple interactions ISO RGD:731551 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] CTD PMID:29471006 neomycin multiple interactions ISO RGD:735691 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 nickel atom increases expression ISO RGD:731551 6480464 Nickel results in increased expression of GCLM mRNA CTD PMID:25583101 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of GCLM mRNA CTD PMID:22110744 nickel sulfate increases expression ISO RGD:731551 6480464 nickel sulfate results in increased expression of GCLM mRNA CTD PMID:16314067 , PMID:20566472 nilotinib multiple interactions ISO RGD:731551 6480464 Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of GCLM mRNA] CTD PMID:23883479 nilotinib increases expression ISO RGD:731551 6480464 nilotinib results in increased expression of GCLM mRNA CTD PMID:23883479 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of GCLM mRNA CTD PMID:24136188 nitisinone multiple interactions ISO RGD:735691 6480464 [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA CTD PMID:12899938 nitric oxide multiple interactions ISO RGD:731551 6480464 GCLM gene SNP affects the abundance of and affects the activity of and affects the susceptibility to Nitric Oxide CTD PMID:12975258 nitrogen dioxide decreases expression EXP 6480464 Nitrogen Dioxide results in decreased expression of GCLM mRNA CTD PMID:16049373 Nonidet P-40 increases expression ISO RGD:731551 6480464 Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 obeticholic acid increases expression ISO RGD:735691 6480464 obeticholic acid results in increased expression of GCLM mRNA CTD PMID:26655953 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of GCLM mRNA CTD PMID:16251485 , PMID:18417182 ochratoxin A decreases expression ISO RGD:731551 6480464 ochratoxin A results in decreased expression of GCLM mRNA CTD PMID:30559759 ochratoxin A affects expression ISO RGD:731551 6480464 ochratoxin A affects the expression of GCLM mRNA CTD PMID:30008028 oleanolic acid increases expression ISO RGD:735691 6480464 Oleanolic Acid results in increased expression of GCLM mRNA CTD PMID:18706400 organoselenium compound multiple interactions ISO RGD:731551 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of GCLM mRNA CTD PMID:25167922 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of GCLM mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GCLM mRNA CTD PMID:25729387 oxidopamine increases expression ISO RGD:731551 6480464 Oxidopamine results in increased expression of GCLM mRNA CTD PMID:33486071 oxidopamine multiple interactions ISO RGD:731551 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] more ... CTD PMID:25446857 , PMID:33486071 oxidopamine decreases expression ISO RGD:731551 6480464 Oxidopamine results in decreased expression of GCLM protein CTD PMID:25446857 oxidopamine multiple interactions EXP 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] CTD PMID:25446857 oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of GCLM protein CTD PMID:25446857 ozone affects response to substance ISO RGD:735691 6480464 GCLM gene mutant form affects the susceptibility to Ozone CTD PMID:20417186 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA CTD PMID:18636392 ozone multiple interactions ISO RGD:735691 6480464 GCLM gene mutant form promotes the reaction [Ozone results in increased expression of MT1 mRNA] more ... CTD PMID:20417186 p-chloromercuribenzoic acid increases expression ISO RGD:731551 6480464 p-Chloromercuribenzoic Acid results in increased expression of GCLM mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of GCLM mRNA CTD PMID:27638505 para-Cresidine increases expression ISO RGD:731551 6480464 cresidine results in increased expression of GCLM mRNA CTD PMID:26198647 paracetamol multiple interactions ISO RGD:731551 6480464 [Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA more ... CTD PMID:25881548 , PMID:33819548 paracetamol decreases expression ISO RGD:735691 6480464 Acetaminophen results in decreased expression of GCLM mRNA CTD PMID:25818464 more ... paracetamol affects response to substance ISO RGD:735691 6480464 GCLM protein affects the susceptibility to Acetaminophen CTD PMID:17584759 paracetamol increases expression ISO RGD:731551 6480464 Acetaminophen results in increased expression of GCLM mRNA CTD PMID:21420995 more ... paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GCLM mRNA CTD PMID:11245408 more ... paracetamol decreases response to substance ISO RGD:735691 6480464 GCLM protein results in decreased susceptibility to Acetaminophen CTD PMID:18642143 paracetamol increases expression ISO RGD:735691 6480464 Acetaminophen results in increased expression of GCLM mRNA, Acetaminophen results in increased expression of GCLM protein CTD PMID:18468992 more ... paracetamol multiple interactions ISO RGD:735691 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA more ... CTD PMID:16840778 more ... paracetamol affects expression ISO RGD:735691 6480464 Acetaminophen affects the expression of GCLM mRNA CTD PMID:17562736 paraoxon increases expression ISO RGD:731551 6480464 Paraoxon results in increased expression of GCLM mRNA CTD PMID:24413757 paraquat increases response to substance ISO RGD:735691 6480464 GCLM gene mutant form results in increased susceptibility to Paraquat CTD PMID:23704229 paraquat increases expression ISO RGD:731551 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:34097952 , PMID:35182771 paraquat increases expression ISO RGD:735691 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:31216030 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GCLM protein CTD PMID:27993944 paraquat increases expression EXP 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:28467894 paraquat multiple interactions ISO RGD:731551 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:24530478 paraquat multiple interactions ISO RGD:735691 6480464 [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine more ... CTD PMID:23704229 , PMID:31216030 PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 pentachlorophenol increases expression ISO RGD:735691 6480464 Pentachlorophenol results in increased expression of GCLM mRNA CTD PMID:23892564 perfluorodecanoic acid increases expression ISO RGD:731551 6480464 perfluorodecanoic acid results in increased expression of GCLM mRNA CTD PMID:23567314 perfluorononanoic acid increases expression ISO RGD:731551 6480464 perfluoro-n-nonanoic acid results in increased expression of GCLM mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression ISO RGD:731551 6480464 perfluorooctane sulfonic acid results in increased expression of GCLM mRNA CTD PMID:33772556 perfluorooctanoic acid decreases expression ISO RGD:735691 6480464 perfluorooctanoic acid results in decreased expression of GCLM mRNA CTD PMID:30547568 perfluorooctanoic acid increases expression ISO RGD:731551 6480464 perfluorooctanoic acid results in increased expression of GCLM mRNA CTD PMID:33772556 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of GCLM mRNA CTD PMID:19162173 phenobarbital affects expression ISO RGD:731551 6480464 Phenobarbital affects the expression of GCLM mRNA CTD PMID:19159669 phenol increases expression ISO RGD:731551 6480464 Phenol results in increased expression of GCLM mRNA CTD PMID:26198647 phenoxymethylpenicillin increases expression ISO RGD:731551 6480464 Penicillin V results in increased expression of GCLM mRNA CTD PMID:22609641 phenyl benzoate increases expression ISO RGD:731551 6480464 diphenylcarboxylate results in increased expression of GCLM mRNA CTD PMID:27965148 phenylmercury acetate increases expression ISO RGD:731551 6480464 Phenylmercuric Acetate results in increased expression of GCLM mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of GCLM mRNA CTD PMID:20345932 phlorizin decreases expression ISO RGD:735691 6480464 Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731551 6480464 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA], Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] CTD PMID:24632381 phorbol 13-acetate 12-myristate increases expression ISO RGD:731551 6480464 Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA CTD PMID:24632381 phorone affects expression EXP 6480464 phorone affects the expression of GCLM mRNA CTD PMID:18198479 phosgene affects expression ISO RGD:735691 6480464 Phosgene affects the expression of GCLM mRNA CTD PMID:16300373 picoxystrobin increases expression ISO RGD:731551 6480464 picoxystrobin results in increased expression of GCLM mRNA CTD PMID:33512557 plumbagin increases expression ISO RGD:731551 6480464 plumbagin results in increased expression of GCLM mRNA CTD PMID:20028456 potassium bromate increases expression ISO RGD:731551 6480464 potassium bromate results in increased expression of GCLM mRNA CTD PMID:30008028 , PMID:30559759 potassium bromate increases methylation ISO RGD:731551 6480464 potassium bromate results in increased methylation of GCLM promoter CTD PMID:30559759 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of GCLM mRNA CTD PMID:19162173 procyanidin B3 multiple interactions ISO RGD:735691 6480464 [Eicosapentaenoic Acid co-treated with procyanidin B3 co-treated with Lipopolysaccharides] results in increased expression of GCLM mRNA CTD PMID:22169119 propan-2-ol increases expression ISO RGD:731551 6480464 2-Propanol results in increased expression of GCLM mRNA CTD PMID:20566472 prostaglandin J2 increases expression EXP 6480464 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM mRNA, 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM protein CTD PMID:18332871 purine-6-thiol increases expression ISO RGD:731551 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 pyrimidifen increases expression ISO RGD:731551 6480464 pyrimidifen results in increased expression of GCLM mRNA CTD PMID:33512557 quercetin increases expression ISO RGD:735691 6480464 Quercetin results in increased expression of GCLM mRNA, Quercetin results in increased expression of GCLM protein CTD PMID:19183254 , PMID:27777014 quercetin increases activity ISO RGD:735691 6480464 Quercetin analog results in increased activity of GCLM protein CTD PMID:27777014 quercetin increases expression ISO RGD:731551 6480464 Quercetin results in increased expression of GCLM mRNA, Quercetin results in increased expression of GCLM protein CTD PMID:19576171 more ... quercetin multiple interactions ISO RGD:731551 6480464 [Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA more ... CTD PMID:22197970 , PMID:25881548 rac-lactic acid increases expression ISO RGD:731551 6480464 Lactic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 reactive oxygen species multiple interactions EXP 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] CTD PMID:22864849 reactive oxygen species decreases abundance ISO RGD:731551 6480464 GCLM gene SNP results in decreased abundance of Reactive Oxygen Species CTD PMID:32715377 reactive oxygen species increases expression ISO RGD:731551 6480464 Reactive Oxygen Species results in increased expression of GCLM mRNA CTD PMID:25800948 resveratrol multiple interactions ISO RGD:731551 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of GCLM mRNA, resveratrol promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:19167446 , PMID:27818126 resveratrol increases expression ISO RGD:735691 6480464 resveratrol results in increased expression of GCLM mRNA CTD PMID:25808216 rotenone increases expression ISO RGD:735691 6480464 Rotenone results in increased expression of GCLM mRNA CTD PMID:17657281 rotenone increases expression ISO RGD:731551 6480464 Rotenone results in increased expression of GCLM mRNA CTD PMID:33512557 rotenone affects expression ISO RGD:735691 6480464 Rotenone affects the expression of GCLM mRNA CTD PMID:23186747 rottlerin multiple interactions ISO RGD:735691 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]] more ... CTD PMID:25895139 more ... S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:731551 6480464 [S-(1 more ... CTD PMID:35811015 S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO RGD:731551 6480464 S-(1, 2-dichlorovinyl)cysteine results in increased expression of GCLM mRNA CTD PMID:35811015 , PMID:36576512 S-(1,2-Dichlorovinyl)glutathione increases expression ISO RGD:731551 6480464 S-(1, 2-dichlorovinyl)glutathione results in increased expression of GCLM mRNA CTD PMID:36576512 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression EXP 6480464 Buthionine Sulfoximine results in increased expression of GCLM mRNA CTD PMID:10978506 , PMID:19010381 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:731551 6480464 Buthionine Sulfoximine inhibits the reaction [[Lithocholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione] CTD PMID:17724089 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] CTD PMID:22864849 SB 203580 multiple interactions ISO RGD:731551 6480464 SB 203580 inhibits the reaction [Quercetin results in increased expression of GCLM mRNA] CTD PMID:22197970 SB 431542 multiple interactions ISO RGD:731551 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:34480604 Securinine increases expression ISO RGD:731551 6480464 securinine results in increased expression of GCLM mRNA CTD PMID:32662633 sevoflurane decreases expression ISO RGD:735691 6480464 Sevoflurane results in decreased expression of GCLM mRNA CTD PMID:35350913 sevoflurane multiple interactions ISO RGD:735691 6480464 alpha-solamargine inhibits the reaction [Sevoflurane results in decreased expression of GCLM mRNA] CTD PMID:35350913 silicon dioxide multiple interactions ISO RGD:735691 6480464 [Silicon Dioxide co-treated with Vitamin D] results in increased expression of GCLM mRNA CTD PMID:30698894 silicon dioxide increases expression ISO RGD:735691 6480464 Silicon Dioxide results in increased expression of GCLM mRNA CTD PMID:30698894 silver atom multiple interactions ISO RGD:731551 6480464 NFE2L2 protein affects the reaction [Silver results in increased expression of GCLM mRNA] CTD PMID:22546375 silver atom increases expression ISO RGD:735691 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:27131904 silver atom increases expression ISO RGD:731551 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:22036727 more ... silver(0) multiple interactions ISO RGD:731551 6480464 NFE2L2 protein affects the reaction [Silver results in increased expression of GCLM mRNA] CTD PMID:22546375 silver(0) increases expression ISO RGD:735691 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:731551 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:22036727 more ... SL-327 multiple interactions ISO RGD:735691 6480464 SL 327 inhibits the reaction [Melatonin inhibits the reaction [KL mutant form results in decreased expression of GCLM mRNA]] CTD PMID:25550330 sodium arsenate multiple interactions ISO RGD:731551 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA, [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of GCLM protein CTD PMID:32525701 , PMID:33434570 sodium arsenite multiple interactions ISO RGD:731551 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:20805060 more ... sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GCLM mRNA, sodium arsenite results in increased expression of GCLM protein CTD PMID:21465251 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of GCLM mRNA CTD PMID:25625412 sodium arsenite increases expression ISO RGD:735691 6480464 sodium arsenite results in increased expression of GCLM mRNA, sodium arsenite results in increased expression of GCLM protein CTD PMID:16014739 more ... sodium arsenite increases response to substance ISO RGD:735691 6480464 GCLM gene mutant form results in increased susceptibility to sodium arsenite CTD PMID:16014739 sodium arsenite multiple interactions ISO RGD:735691 6480464 [GCLM co-treated with GCLC] inhibits the reaction [sodium arsenite results in increased activity of and results in increased cleavage of CASP3 protein] more ... CTD PMID:20006689 , PMID:34272803 sodium arsenite increases expression ISO RGD:731551 6480464 sodium arsenite results in increased expression of GCLM mRNA, sodium arsenite results in increased expression of GCLM protein CTD PMID:12679051 more ... sodium dichromate increases expression ISO RGD:735691 6480464 sodium bichromate results in increased expression of GCLM mRNA CTD PMID:22155349 sodium dichromate decreases expression ISO RGD:735691 6480464 sodium bichromate results in decreased expression of GCLM mRNA CTD PMID:22155349 sodium dodecyl sulfate increases expression ISO RGD:731551 6480464 Sodium Dodecyl Sulfate results in increased expression of GCLM mRNA CTD PMID:20566472 spermidine multiple interactions ISO RGD:735691 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of GCLM mRNA] CTD PMID:12763045 spermidine increases expression ISO RGD:735691 6480464 Spermidine results in increased expression of GCLM mRNA CTD PMID:12763045 staurosporine multiple interactions ISO RGD:731551 6480464 Staurosporine promotes the reaction [MYC protein binds to GCLM promoter] CTD PMID:17628013 streptozocin multiple interactions ISO RGD:735691 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA CTD PMID:33359794 succimer multiple interactions ISO RGD:735691 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of GCLM mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of GCLM mRNA CTD PMID:21641980 , PMID:26378955 sulforaphane multiple interactions ISO RGD:735691 6480464 NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLM mRNA] more ... CTD PMID:20932822 more ... sulforaphane decreases expression ISO RGD:731551 6480464 sulforaphane results in decreased expression of GCLM mRNA CTD PMID:35724838 sulforaphane multiple interactions ISO RGD:731551 6480464 NFE2L2 protein affects the reaction [sulforaphane results in increased expression of GCLM protein] CTD PMID:35227738 sulforaphane increases expression ISO RGD:735691 6480464 sulforaphane results in increased expression of GCLM mRNA, sulforaphane results in increased expression of GCLM protein CTD PMID:19071154 more ... sulforaphane increases expression ISO RGD:731551 6480464 sulforaphane results in increased expression of GCLM more ... CTD PMID:20442190 more ... sunitinib increases expression ISO RGD:731551 6480464 Sunitinib results in increased expression of GCLM mRNA CTD PMID:31533062 Sunset Yellow FCF multiple interactions ISO RGD:731551 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA CTD PMID:33819548 suprofen increases expression ISO RGD:731551 6480464 Suprofen results in increased expression of GCLM mRNA CTD PMID:11909699 T-2 toxin decreases expression ISO RGD:735691 6480464 T-2 Toxin results in decreased expression of GCLM mRNA CTD PMID:20854872 T-2 toxin increases expression ISO RGD:735691 6480464 T-2 Toxin results in increased expression of GCLM mRNA CTD PMID:33508416 tartrazine multiple interactions ISO RGD:731551 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of GCLM mRNA CTD PMID:33819548 tebufenpyrad increases expression ISO RGD:731551 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of GCLM mRNA CTD PMID:33512557 temozolomide increases expression ISO RGD:731551 6480464 Temozolomide results in increased expression of GCLM mRNA CTD PMID:31758290 tert-butyl hydroperoxide multiple interactions EXP 6480464 [Apigenin results in increased expression of GCLM mRNA] which results in decreased susceptibility to tert-Butylhydroperoxide more ... CTD PMID:22864849 tert-butyl hydroperoxide increases expression ISO RGD:735691 6480464 tert-Butylhydroperoxide results in increased expression of GCLM mRNA CTD PMID:30547568 tert-butyl hydroperoxide increases expression ISO RGD:731551 6480464 tert-Butylhydroperoxide results in increased expression of GCLM mRNA CTD PMID:12414654 more ... tetrachloromethane affects expression ISO RGD:735691 6480464 Carbon Tetrachloride affects the expression of GCLM mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:735691 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein] more ... CTD PMID:27477297 , PMID:29964319 tetrachloromethane decreases expression ISO RGD:735691 6480464 Carbon Tetrachloride results in decreased expression of GCLM mRNA, Carbon Tetrachloride results in decreased expression of GCLM protein CTD PMID:17484886 more ... tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of GCLM mRNA CTD PMID:15963342 tetramethylpyrazine multiple interactions ISO RGD:735691 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM mRNA]] more ... CTD PMID:27477297 thifluzamide increases expression ISO RGD:731551 6480464 thifluzamide results in increased expression of GCLM mRNA CTD PMID:33512557 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of GCLM mRNA, Thioacetamide results in increased expression of GCLM protein CTD PMID:10486302 more ... thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of GCLM mRNA CTD PMID:34492290 thiram increases expression ISO RGD:731551 6480464 Thiram results in increased expression of GCLM mRNA CTD PMID:23999411 more ... titanium dioxide multiple interactions ISO RGD:735691 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLM mRNA CTD PMID:29950665 toluene increases expression ISO RGD:731551 6480464 Toluene results in increased expression of GCLM mRNA CTD PMID:28245982 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GCLM mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of GCLM mRNA CTD PMID:25729387 trans-chalcone increases expression ISO RGD:731551 6480464 Chalcone analog results in increased expression of GCLM mRNA, Chalcone analog results in increased expression of GCLM protein CTD PMID:31299238 trans-isoeugenol increases expression ISO RGD:731551 6480464 isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... triacsin C increases expression ISO RGD:731551 6480464 triacsin C results in increased expression of GCLM mRNA CTD PMID:16704987 tributylstannane multiple interactions ISO RGD:735691 6480464 PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLM mRNA] CTD PMID:25895139 Tributyltin oxide decreases expression ISO RGD:731551 6480464 bis(tri-n-butyltin)oxide results in decreased expression of GCLM mRNA CTD PMID:26198647 Tributyltin oxide increases expression ISO RGD:731551 6480464 bis(tri-n-butyltin)oxide results in increased expression of GCLM mRNA CTD PMID:21601586 Tributyltin oxide increases expression ISO RGD:735691 6480464 bis(tri-n-butyltin)oxide results in increased expression of GCLM mRNA CTD PMID:21601586 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of GCLM mRNA CTD PMID:19448997 , PMID:33387578 trichostatin A affects expression ISO RGD:731551 6480464 trichostatin A affects the expression of GCLM mRNA CTD PMID:28542535 trimethyltin multiple interactions ISO RGD:735691 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]], rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA] CTD PMID:25895139 trimethyltin increases expression ISO RGD:735691 6480464 trimethyltin results in increased expression of GCLM mRNA CTD PMID:25895139 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of GCLM mRNA CTD PMID:30589522 tris(2-butoxyethyl) phosphate decreases response to substance ISO RGD:735691 6480464 GCLM protein results in decreased susceptibility to tris(2-butoxyethyl) phosphate CTD PMID:25797475 Tungsten carbide multiple interactions ISO RGD:731551 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of GCLM mRNA CTD PMID:23052192 tunicamycin decreases expression ISO RGD:735691 6480464 Tunicamycin results in decreased expression of GCLM mRNA CTD PMID:17127020 tunicamycin increases expression ISO RGD:731551 6480464 Tunicamycin results in increased expression of GCLM mRNA CTD PMID:36586010 tunicamycin decreases expression ISO RGD:731551 6480464 Tunicamycin results in decreased expression of GCLM mRNA CTD PMID:29453283 undecanal increases expression ISO RGD:731551 6480464 undecanal analog results in increased expression of GCLM mRNA CTD PMID:27965148 ursodeoxycholic acid multiple interactions ISO RGD:731551 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GCLM mRNA], Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 ursodeoxycholic acid increases expression ISO RGD:731551 6480464 Ursodeoxycholic Acid results in increased expression of GCLM mRNA CTD PMID:19073151 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of GCLM mRNA CTD PMID:24136188 valproic acid multiple interactions ISO RGD:731551 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:731551 6480464 Valproic Acid results in increased expression of GCLM mRNA CTD PMID:23179753 more ... vancomycin multiple interactions ISO RGD:735691 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 vanillin increases expression ISO RGD:731551 6480464 vanillin results in increased expression of GCLM mRNA CTD PMID:17178418 vincristine multiple interactions ISO RGD:731551 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine CTD PMID:10900222 vincristine decreases expression ISO RGD:731551 6480464 Vincristine results in decreased expression of GCLM mRNA CTD PMID:23649840 vitamin D increases expression ISO RGD:735691 6480464 Vitamin D results in increased expression of GCLM mRNA CTD PMID:30698894 vitamin D multiple interactions ISO RGD:735691 6480464 [Particulate Matter co-treated with Vitamin D] results in increased expression of GCLM mRNA, [Silicon Dioxide co-treated with Vitamin D] results in increased expression of GCLM mRNA CTD PMID:30698894 vitamin E multiple interactions EXP 6480464 Vitamin E affects the reaction [[REL binds to GCLM promoter] which affects the expression of GCLM mRNA] CTD PMID:16298738 vitamin E affects expression EXP 6480464 Vitamin E affects the expression of GCLM mRNA CTD PMID:16298738 , PMID:20447326 wortmannin multiple interactions ISO RGD:731551 6480464 Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]] CTD PMID:34077701 XAV939 multiple interactions ISO RGD:731551 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA, [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 zinc acetate increases expression ISO RGD:731551 6480464 Zinc Acetate results in increased expression of GCLM mRNA CTD PMID:16357179 zinc acetate multiple interactions ISO RGD:731551 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA CTD PMID:16357179 zinc atom decreases expression ISO RGD:731551 6480464 Zinc deficiency results in decreased expression of GCLM mRNA, Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of GCLM mRNA, Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 zinc dichloride multiple interactions ISO RGD:731551 6480464 zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 zinc oxide multiple interactions ISO RGD:735691 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] more ... CTD PMID:30500950 more ... zinc oxide increases expression ISO RGD:735691 6480464 Zinc Oxide analog results in increased expression of GCLM mRNA, Zinc Oxide analog results in increased expression of GCLM protein CTD PMID:35247504 more ... zinc oxide multiple interactions ISO RGD:731551 6480464 RU.521 inhibits the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36368621 zinc oxide increases expression ISO RGD:731551 6480464 Zinc Oxide analog results in increased expression of GCLM protein CTD PMID:36368621 zinc(0) decreases expression ISO RGD:731551 6480464 Zinc deficiency results in decreased expression of GCLM mRNA, Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of GCLM mRNA, Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617