Ankrd10 (ankyrin repeat domain 10) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ankrd10 (ankyrin repeat domain 10) Rattus norvegicus
Analyze
Symbol: Ankrd10
Name: ankyrin repeat domain 10
RGD ID: 1310501
Description: Predicted to be located in nucleoplasm. Orthologous to human ANKRD10 (ankyrin repeat domain 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ankyrin repeat domain-containing protein 10; LOC361183
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81684,566,021 - 84,591,849 (+)NCBIGRCr8
mRatBN7.21677,866,489 - 77,889,745 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1677,864,261 - 77,889,745 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1683,146,972 - 83,170,221 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01686,599,610 - 86,622,859 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01681,841,711 - 81,864,966 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01683,205,898 - 83,229,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1683,206,004 - 83,228,194 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01682,674,123 - 82,697,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41682,719,075 - 82,742,218 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11682,683,443 - 82,728,069 (+)NCBI
Celera1675,666,484 - 75,689,725 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
chlorpyrifos  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
entinostat  (ISO)
etoposide  (ISO)
flusilazole  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gentamycin  (EXP)
hexaconazole  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
melphalan  (ISO)
mercury dichloride  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
mifepristone  (ISO)
mono(2-ethyl-5-oxohexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methylformamide  (ISO)
ozone  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
topotecan  (ISO)
triadimefon  (ISO)
Tributyltin oxide  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Ankrd10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81684,566,021 - 84,591,849 (+)NCBIGRCr8
mRatBN7.21677,866,489 - 77,889,745 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1677,864,261 - 77,889,745 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1683,146,972 - 83,170,221 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01686,599,610 - 86,622,859 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01681,841,711 - 81,864,966 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01683,205,898 - 83,229,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1683,206,004 - 83,228,194 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01682,674,123 - 82,697,366 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41682,719,075 - 82,742,218 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11682,683,443 - 82,728,069 (+)NCBI
Celera1675,666,484 - 75,689,725 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
ANKRD10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813110,878,540 - 110,915,069 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13110,878,540 - 110,915,069 (-)EnsemblGRCh38hg38GRCh38
GRCh3713111,530,887 - 111,567,416 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613110,328,888 - 110,365,417 (-)NCBINCBI36Build 36hg18NCBI36
Build 3413110,328,888 - 110,365,417NCBI
Celera1392,377,096 - 92,413,637 (-)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1392,129,277 - 92,165,583 (-)NCBIHuRef
CHM1_113111,499,320 - 111,535,592 (-)NCBICHM1_1
T2T-CHM13v2.013110,108,631 - 110,144,952 (-)NCBIT2T-CHM13v2.0
Ankrd10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39811,661,581 - 11,694,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl811,661,583 - 11,685,757 (-)EnsemblGRCm39 Ensembl
GRCm38811,611,581 - 11,635,926 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl811,611,583 - 11,635,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37811,611,583 - 11,635,754 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36811,611,555 - 11,635,661 (-)NCBIMGSCv36mm8
Celera811,786,923 - 11,811,099 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
Ankrd10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554041,928,307 - 1,954,193 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554041,928,285 - 1,954,193 (+)NCBIChiLan1.0ChiLan1.0
ANKRD10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214112,376,756 - 112,413,464 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113111,058,602 - 111,105,031 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01392,017,092 - 92,053,485 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113111,130,933 - 111,177,018 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13111,130,933 - 111,177,018 (-)Ensemblpanpan1.1panPan2
ANKRD10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12259,059,329 - 59,092,225 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2259,059,519 - 59,092,192 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2258,769,806 - 58,802,697 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02259,682,861 - 59,715,796 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2259,682,861 - 59,715,782 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12259,184,535 - 59,217,419 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02259,176,685 - 59,209,568 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02259,212,161 - 59,245,075 (-)NCBIUU_Cfam_GSD_1.0
Ankrd10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945193,896,199 - 193,926,454 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364722,025,695 - 2,056,126 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364722,025,701 - 2,055,956 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1177,323,358 - 77,356,112 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11177,323,355 - 77,356,049 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ANKRD10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1389,094,308 - 89,130,685 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl389,094,218 - 89,130,686 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604645,862,635 - 45,899,111 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247932,046,912 - 2,071,784 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247932,046,796 - 2,072,603 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ankrd10
60 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:130
Count of miRNA genes:100
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000018870
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 32 16 19 16 8 11 74 35 40 11 8
Low 25 25 25 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000018870   ⟹   ENSRNOP00000018870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1683,206,004 - 83,228,194 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095735   ⟹   ENSRNOP00000089615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1677,864,261 - 77,889,745 (+)Ensembl
RefSeq Acc Id: NM_001271219   ⟹   NP_001258148
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,568,599 - 84,591,849 (+)NCBI
mRatBN7.21677,866,489 - 77,889,745 (+)NCBI
Rnor_6.01683,205,898 - 83,229,147 (+)NCBI
Rnor_5.01682,674,123 - 82,697,366 (+)NCBI
Celera1675,666,484 - 75,689,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253453   ⟹   XP_006253515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,569,135 - 84,591,847 (+)NCBI
mRatBN7.21677,867,107 - 77,889,745 (+)NCBI
Rnor_6.01683,206,479 - 83,229,147 (+)NCBI
Rnor_5.01682,674,123 - 82,697,366 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253454   ⟹   XP_006253516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,570,470 - 84,591,847 (+)NCBI
mRatBN7.21677,868,357 - 77,889,745 (+)NCBI
Rnor_6.01683,206,835 - 83,229,147 (+)NCBI
Rnor_5.01682,674,123 - 82,697,366 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006253459   ⟹   XP_006253521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,575,992 - 84,591,847 (+)NCBI
mRatBN7.21677,869,047 - 77,889,745 (+)NCBI
Rnor_6.01683,220,299 - 83,229,147 (+)NCBI
Rnor_5.01682,674,123 - 82,697,366 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094691   ⟹   XP_038950619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,571,076 - 84,591,847 (+)NCBI
mRatBN7.21677,868,966 - 77,889,745 (+)NCBI
RefSeq Acc Id: XM_039094692   ⟹   XP_038950620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,571,076 - 84,591,847 (+)NCBI
mRatBN7.21677,868,966 - 77,889,745 (+)NCBI
RefSeq Acc Id: XM_063275579   ⟹   XP_063131649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,575,992 - 84,591,847 (+)NCBI
RefSeq Acc Id: XM_063275580   ⟹   XP_063131650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81684,566,021 - 84,583,020 (+)NCBI
RefSeq Acc Id: NP_001258148   ⟸   NM_001271219
- UniProtKB: F1LPK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253515   ⟸   XM_006253453
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006253516   ⟸   XM_006253454
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006253521   ⟸   XM_006253459
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000018870   ⟸   ENSRNOT00000018870
RefSeq Acc Id: XP_038950619   ⟸   XM_039094691
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950620   ⟸   XM_039094692
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000089615   ⟸   ENSRNOT00000095735
RefSeq Acc Id: XP_063131650   ⟸   XM_063275580
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131649   ⟸   XM_063275579
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LPK2-F1-model_v2 AlphaFold F1LPK2 1-415 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310501 AgrOrtholog
BioCyc Gene G2FUF-10659 BioCyc
Ensembl Genes ENSRNOG00000013618 Ensembl
  ENSRNOG00000064616 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000095735.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7374447 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
MGC_CLONE MGC:112811 IMAGE-MGC_LOAD
NCBI Gene 361183 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 10 UniProtKB/TrEMBL
  ANKYRIN REPEAT FAMILY PROTEIN UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
PhenoGen Ankrd10 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013618 RatGTEx
  ENSRNOG00000064616 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8I6AA84_RAT UniProtKB/TrEMBL
  A6IWN7_RAT UniProtKB/TrEMBL
  A6IWN8_RAT UniProtKB/TrEMBL
  A6IWN9_RAT UniProtKB/TrEMBL
  A6IWP0_RAT UniProtKB/TrEMBL
  F1LPK2 ENTREZGENE
  Q4G039_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ankrd10  ankyrin repeat domain 10  Ankrd10_predicted  ankyrin repeat domain 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ankrd10_predicted  ankyrin repeat domain 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED