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Gene: Gls2 (glutaminase 2) Rattus norvegicus
Symbol: Gls2
Name: glutaminase 2
RGD ID: 620359
Description: Predicted to have glutaminase activity. Predicted to be involved in glutamine family amino acid metabolic process; reactive oxygen species metabolic process; and regulation of apoptotic process. Predicted to localize to mitochondrion. Orthologous to human GLS2 (glutaminase 2); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; argininosuccinic aciduria pathway; carbamoyl phosphate synthetase I deficiency pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ga; GLS; glutaminase 2 (liver, mitochondrial); glutaminase liver isoform, mitochondrial; glutaminase variant 2; glutaminase variant 3; glutaminase variant 4; glutaminase variant 5; glutaminase variant 6; glutaminase variant 8; L-glutaminase; L-glutamine amidohydrolase; liver mitochondrial glutaminase
Homo sapiens (human) : GLS2 (glutaminase 2)  HGNC  Alliance
Mus musculus (house mouse) : Gls2 (glutaminase 2 (liver, mitochondrial))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gls2 (glutaminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GLS2 (glutaminase 2)
Canis lupus familiaris (dog) : GLS2 (glutaminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gls2 (glutaminase 2)
Sus scrofa (pig) : GLS2 (glutaminase 2)
Chlorocebus sabaeus (African green monkey) : GLS2 (glutaminase 2)
Heterocephalus glaber (naked mole-rat) : Gls2 (glutaminase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.072,605,679 - 2,621,853 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,605,719 - 2,621,852 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,584,594 - 2,600,729 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,484,397 - 1,495,283 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,484,396 - 1,495,283 (+)NCBI
Celera7495,890 - 511,971 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gls2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620359
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.