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Gene: Mdc1 (mediator of DNA damage checkpoint 1) Rattus norvegicus
Symbol: Mdc1
Name: mediator of DNA damage checkpoint 1
Description: Predicted to have FHA domain binding activity; identical protein binding activity; and protein C-terminus binding activity. Predicted to be involved in DNA repair. Predicted to localize to the chromosome; focal adhesion; and nuclear body. Orthologous to human MDC1 (mediator of DNA damage checkpoint 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0170; mediator of DNA damage checkpoint protein 1
Homo sapiens (human) : MDC1 (mediator of DNA damage checkpoint 1)  HGNC  Alliance
Mus musculus (house mouse) : Mdc1 (mediator of DNA damage checkpoint 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mdc1 (mediator of DNA damage checkpoint 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MDC1 (mediator of DNA damage checkpoint 1)
Canis lupus familiaris (dog) : MDC1 (mediator of DNA damage checkpoint 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mdc1 (mediator of DNA damage checkpoint 1)
Sus scrofa (pig) : MDC1 (mediator of DNA damage checkpoint 1)
Chlorocebus sabaeus (green monkey) : MDC1 (mediator of DNA damage checkpoint 1)
Heterocephalus glaber (naked mole-rat) : Mdc1 (mediator of DNA damage checkpoint 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,405,017 - 3,419,831 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,404,711 - 3,419,831 (-)Ensembl
Rnor_5.0205,502,120 - 5,516,934 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,042,953 - 3,057,607 (-)NCBIRGSC3.4rn4RGSC3.4
Celera20321,426 - 336,070 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mdc1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559468
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.