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Gene: Cycs (cytochrome c, somatic) Rattus norvegicus
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Symbol: Cycs
Name: cytochrome c, somatic
Description: Exhibits enzyme binding activity. Involved in several processes, including mitochondrial electron transport, cytochrome c to oxygen; negative regulation of hydrogen peroxide biosynthetic process; and response to ischemia. Localizes to the cytosol and mitochondrion. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic); PARTICIPATES IN intrinsic apoptotic pathway; cardiolipin metabolic pathway; ceramide signaling pathway; INTERACTS WITH (+)-taxifolin; (R)-adrenaline; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CYCSA; Cytochrome C expressed in somatic tissues; Cytochrome C, expressed in somatic tissues; MGC93634
Orthologs:
Homo sapiens (human) : CYCS (cytochrome c, somatic)  HGNC  Alliance
Mus musculus (house mouse) : Cycs (cytochrome c, somatic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023786 (cytochrome c, somatic)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986481 (cytochrome c)
Canis lupus familiaris (dog) : CYCS (cytochrome c, somatic)
Sus scrofa (pig) : CYCS (cytochrome c, somatic)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0480,331,226 - 80,333,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04145,002,156 - 145,004,256 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,825,878 - 78,827,978 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1479,102,008 - 79,104,108 (-)NCBI
Celera474,558,589 - 74,560,689 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cycs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2451
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-06-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.