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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (2E,4E)-hexa-2,4-dienoic acid | increases expression | ISO | RGD:1315620 | 6480464 | Sorbic Acid results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1315620 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of RAD51AP1 mRNA | CTD | PMID:22206623 | 1,4-dioxane | increases expression | ISO | RGD:1315620 | 6480464 | 1, 4-dioxane results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of RAD51AP1 mRNA | CTD | PMID:30723492 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1315620 | 6480464 | Ethinyl Estradiol affects the expression of RAD51AP1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1315620 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAD51AP1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | RGD:1353541 | 6480464 | Estradiol results in increased expression of RAD51AP1 mRNA | CTD | PMID:16474171 more ... | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1315620 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1315620 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1315620 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAD51AP1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1315620 | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAD51AP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1353541 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21632981, PMID:21802500 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1315620 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAD51AP1 mRNA | CTD | PMID:17942748 | 2,4-diaminotoluene | increases expression | ISO | RGD:1315620 | 6480464 | 2, 4-diaminotoluene results in increased expression of RAD51AP1 mRNA | CTD | PMID:20713471 | 2,6-di-tert-butyl-4-methylphenol | increases expression | ISO | RGD:1315620 | 6480464 | Butylated Hydroxytoluene results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | 2-butoxyethanol | increases expression | ISO | RGD:1315620 | 6480464 | n-butoxyethanol results in increased expression of RAD51AP1 mRNA | CTD | PMID:19812364 | 3-methylcholanthrene | increases expression | ISO | RGD:1315620 | 6480464 | Methylcholanthrene results in increased expression of RAD51AP1 mRNA | CTD | PMID:20713471 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1315620 | 6480464 | Fenretinide results in increased expression of RAD51AP1 mRNA | CTD | PMID:28973697 | 7,12-dimethyltetraphene | increases expression | ISO | RGD:1315620 | 6480464 | 9 more ... | CTD | PMID:20025956 | 8'-apo-beta,psi-caroten-8'-al | increases expression | ISO | RGD:1353541 | 6480464 | apocarotenal results in increased expression of RAD51AP1 mRNA | CTD | PMID:17034753 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of RAD51AP1 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | ISO | RGD:1315620 | 6480464 | Acrylamide results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of RAD51AP1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | affects expression | ISO | RGD:1353541 | 6480464 | Aflatoxin B1 affects the expression of RAD51AP1 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | RGD:1315620 | 6480464 | Aflatoxin B1 results in decreased expression of RAD51AP1 mRNA | CTD | PMID:19770486 | aflatoxin M1 | decreases expression | ISO | RGD:1353541 | 6480464 | Aflatoxin M1 results in decreased expression of RAD51AP1 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | increases expression | ISO | RGD:1315620 | 6480464 | Tretinoin results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | anthracene-1,8,9-triol | increases expression | ISO | RGD:1315620 | 6480464 | Anthralin results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | azathioprine | decreases expression | ISO | RGD:1353541 | 6480464 | Azathioprine results in decreased expression of RAD51AP1 mRNA | CTD | PMID:22623647 | benzo[a]pyrene | decreases expression | ISO | RGD:1315620 | 6480464 | Benzoapyrene results in decreased expression of RAD51AP1 mRNA | CTD | PMID:19770486, PMID:21569818 | benzo[a]pyrene | increases expression | ISO | RGD:1353541 | 6480464 | Benzoapyrene results in increased expression of RAD51AP1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases expression | ISO | RGD:1315620 | 6480464 | Benzoapyrene results in increased expression of RAD51AP1 mRNA | CTD | PMID:20713471, PMID:22610609 | benzo[a]pyrene | decreases expression | ISO | RGD:1353541 | 6480464 | Benzoapyrene results in decreased expression of RAD51AP1 mRNA | CTD | PMID:20064835, PMID:21802500 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1353541 | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[b]fluoranthene | increases expression | ISO | RGD:1315620 | 6480464 | benzobfluoranthene results in increased expression of RAD51AP1 mRNA | CTD | PMID:26377693 | beta-carotene | decreases expression | ISO | RGD:1353541 | 6480464 | beta Carotene results in decreased expression of RAD51AP1 mRNA | CTD | PMID:17034753 | bis(2-chloroethyl) sulfide | decreases expression | ISO | RGD:1353541 | 6480464 | Mustard Gas results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25102026 | bisphenol A | increases expression | ISO | RGD:1353541 | 6480464 | bisphenol A results in increased expression of RAD51AP1 mRNA | CTD | PMID:16474171 | bisphenol A | affects expression | ISO | RGD:1353541 | 6480464 | bisphenol A affects the expression of RAD51AP1 mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | ISO | RGD:1353541 | 6480464 | bisphenol A results in decreased expression of RAD51AP1 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of RAD51AP1 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1315620 | 6480464 | bisphenol A results in decreased expression of RAD51AP1 mRNA | CTD | PMID:26063408 | buta-1,3-diene | increases expression | ISO | RGD:1315620 | 6480464 | 1, 3-butadiene results in increased expression of RAD51AP1 mRNA | CTD | PMID:29038090 | butylated hydroxyanisole | increases expression | ISO | RGD:1315620 | 6480464 | Butylated Hydroxyanisole results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | cadmium dichloride | increases expression | ISO | RGD:1353541 | 6480464 | Cadmium Chloride results in increased expression of RAD51AP1 mRNA | CTD | PMID:26472689 | caffeine | increases expression | ISO | RGD:1315620 | 6480464 | Caffeine results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | calcitriol | multiple interactions | ISO | RGD:1353541 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21592394 | calcitriol | decreases expression | ISO | RGD:1353541 | 6480464 | Calcitriol results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21592394 | carbon nanotube | increases expression | ISO | RGD:1315620 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | choline | multiple interactions | ISO | RGD:1315620 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAD51AP1 mRNA | CTD | PMID:20938992 | cisplatin | decreases phosphorylation | ISO | RGD:1315620 | 6480464 | Cisplatin results in decreased phosphorylation of RAD51AP1 protein | CTD | PMID:22006019 | cisplatin | increases expression | ISO | RGD:1353541 | 6480464 | Cisplatin results in increased expression of RAD51AP1 mRNA | CTD | PMID:27594783 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of RAD51AP1 mRNA | CTD | PMID:24386269 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of RAD51AP1 mRNA | CTD | PMID:26033743 | copper atom | multiple interactions | ISO | RGD:1353541 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RAD51AP1 mRNA | CTD | PMID:20971185 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of RAD51AP1 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | ISO | RGD:1353541 | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of RAD51AP1 mRNA | CTD | PMID:20971185 | copper(II) sulfate | decreases expression | ISO | RGD:1353541 | 6480464 | Copper Sulfate results in decreased expression of RAD51AP1 mRNA | CTD | PMID:19549813 | coumestrol | multiple interactions | ISO | RGD:1353541 | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | RGD:1353541 | 6480464 | Coumestrol results in increased expression of RAD51AP1 mRNA | CTD | PMID:19167446 | cyclosporin A | decreases expression | ISO | RGD:1353541 | 6480464 | Cyclosporine results in decreased expression of RAD51AP1 mRNA | CTD | PMID:20106945 more ... | dibutyl phthalate | decreases expression | ISO | RGD:1315620 | 6480464 | Dibutyl Phthalate results in decreased expression of RAD51AP1 mRNA | CTD | PMID:17361019, PMID:21266533 | dicrotophos | decreases expression | ISO | RGD:1353541 | 6480464 | dicrotophos results in decreased expression of RAD51AP1 mRNA | CTD | PMID:28302478 | dioxygen | decreases expression | ISO | RGD:1353541 | 6480464 | Oxygen deficiency results in decreased expression of RAD51AP1 mRNA | CTD | PMID:26516004 | doxorubicin | decreases expression | ISO | RGD:1353541 | 6480464 | Doxorubicin results in decreased expression of RAD51AP1 mRNA | CTD | PMID:30031762 | Enterolactone | multiple interactions | ISO | RGD:1353541 | 6480464 | [Coumestrol co-treated with 2, 3-bis3'-hydroxybenzylbutyrolactone] results in increased expression of RAD51AP1 mRNA | CTD | PMID:19167446 | ethyl methanesulfonate | increases expression | ISO | RGD:1353541 | 6480464 | Ethyl Methanesulfonate results in increased expression of RAD51AP1 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | ISO | RGD:1315620 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAD51AP1 mRNA | CTD | PMID:20938992 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RAD51AP1 mRNA | CTD | PMID:25539665 | genistein | increases expression | ISO | RGD:1353541 | 6480464 | Genistein results in increased expression of RAD51AP1 mRNA | CTD | PMID:16474171 | imiquimod | decreases expression | ISO | RGD:1315620 | 6480464 | imiquimod results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21878529 | iron dichloride | increases expression | ISO | RGD:1315620 | 6480464 | ferrous chloride results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | iron trichloride | increases expression | ISO | RGD:1315620 | 6480464 | ferric chloride results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | L-methionine | multiple interactions | ISO | RGD:1315620 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RAD51AP1 mRNA | CTD | PMID:20938992 | lucanthone | decreases expression | ISO | RGD:1353541 | 6480464 | Lucanthone results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21148553 | MeIQx | increases expression | ISO | RGD:1353541 | 6480464 | 2-amino-3 more ... | CTD | PMID:20816883 | methamphetamine | decreases expression | ISO | RGD:1353541 | 6480464 | Methamphetamine results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25290377 | methyl methanesulfonate | increases expression | ISO | RGD:1353541 | 6480464 | Methyl Methanesulfonate results in increased expression of RAD51AP1 mRNA | CTD | PMID:23649840 | Mezerein | increases expression | ISO | RGD:1315620 | 6480464 | mezerein results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | N-nitrosodiethylamine | increases expression | ISO | RGD:1315620 | 6480464 | Diethylnitrosamine results in increased expression of RAD51AP1 mRNA | CTD | PMID:17854601 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:1315620 | 6480464 | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAD51AP1 mRNA] | CTD | PMID:17854601 | N-Nitrosopyrrolidine | decreases expression | ISO | RGD:1353541 | 6480464 | N-Nitrosopyrrolidine results in decreased expression of RAD51AP1 mRNA | CTD | PMID:32234424 | nickel atom | increases expression | ISO | RGD:1353541 | 6480464 | Nickel results in increased expression of RAD51AP1 mRNA | CTD | PMID:25583101 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | RGD:1315620 | 6480464 | [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of RAD51AP1 mRNA | CTD | PMID:25658374 | palbociclib | decreases expression | ISO | RGD:1353541 | 6480464 | palbociclib results in decreased expression of RAD51AP1 mRNA | CTD | PMID:22869556 | palytoxin | increases expression | ISO | RGD:1315620 | 6480464 | palytoxin results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | paracetamol | increases expression | ISO | RGD:1315620 | 6480464 | Acetaminophen results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | paracetamol | decreases expression | ISO | RGD:1353541 | 6480464 | Acetaminophen results in decreased expression of RAD51AP1 mRNA | CTD | PMID:29067470 | paracetamol | increases expression | ISO | RGD:1353541 | 6480464 | Acetaminophen results in increased expression of RAD51AP1 mRNA | CTD | PMID:22230336 | PCB138 | multiple interactions | ISO | RGD:1315620 | 6480464 | [2 more ... | CTD | PMID:25510870 | phenacetin | increases expression | ISO | RGD:1315620 | 6480464 | Phenacetin results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | phenobarbital | increases expression | ISO | RGD:1315620 | 6480464 | Phenobarbital results in increased expression of RAD51AP1 mRNA | CTD | PMID:23091169 | phorbol 13-acetate 12-myristate | increases expression | ISO | RGD:1353541 | 6480464 | Tetradecanoylphorbol Acetate results in increased expression of RAD51AP1 mRNA | CTD | PMID:19031421 | phorbol 13-acetate 12-myristate | increases expression | ISO | RGD:1315620 | 6480464 | Tetradecanoylphorbol Acetate results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | pirinixic acid | multiple interactions | ISO | RGD:1353541 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RAD51AP1 mRNA | CTD | PMID:19710929 | piroxicam | decreases expression | ISO | RGD:1353541 | 6480464 | Piroxicam results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21858171 | progesterone | increases expression | ISO | RGD:1315620 | 6480464 | Progesterone results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | propanal | decreases expression | ISO | RGD:1353541 | 6480464 | propionaldehyde results in decreased expression of RAD51AP1 mRNA | CTD | PMID:26079696 | quercetin | increases expression | ISO | RGD:1353541 | 6480464 | Quercetin results in increased expression of RAD51AP1 mRNA | CTD | PMID:21632981 | resveratrol | decreases expression | ISO | RGD:1353541 | 6480464 | resveratrol results in decreased expression of RAD51AP1 mRNA | CTD | PMID:15767336 | resveratrol | multiple interactions | ISO | RGD:1353541 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of RAD51AP1 mRNA | CTD | PMID:19167446 | rotenone | increases expression | ISO | RGD:1353541 | 6480464 | Rotenone results in increased expression of RAD51AP1 mRNA | CTD | PMID:18191903 | silicon dioxide | decreases expression | ISO | RGD:1353541 | 6480464 | Silicon Dioxide analog results in decreased expression of RAD51AP1 mRNA | CTD | PMID:23806026 | silicon dioxide | increases expression | ISO | RGD:1315620 | 6480464 | Silicon Dioxide results in increased expression of RAD51AP1 mRNA | CTD | PMID:29341224 | sodium arsenite | affects methylation | ISO | RGD:1353541 | 6480464 | sodium arsenite affects the methylation of RAD51AP1 gene | CTD | PMID:28589171 | sodium arsenite | increases expression | ISO | RGD:1353541 | 6480464 | sodium arsenite results in increased expression of RAD51AP1 mRNA | CTD | PMID:29301061 | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of RAD51AP1 mRNA | CTD | PMID:22110744 | sodium nitrite | increases expression | ISO | RGD:1315620 | 6480464 | Sodium Nitrite results in increased expression of RAD51AP1 protein | CTD | PMID:20025956 | sulfadimethoxine | increases expression | ISO | RGD:1315620 | 6480464 | Sulfadimethoxine results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | sunitinib | decreases expression | ISO | RGD:1353541 | 6480464 | Sunitinib results in decreased expression of RAD51AP1 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | RGD:1315620 | 6480464 | Tamoxifen affects the expression of RAD51AP1 mRNA | CTD | PMID:17555576 | testosterone | decreases expression | ISO | RGD:1353541 | 6480464 | Testosterone results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21592394 | testosterone | multiple interactions | ISO | RGD:1353541 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of RAD51AP1 mRNA | CTD | PMID:21592394 | tetrachloromethane | affects expression | ISO | RGD:1315620 | 6480464 | Carbon Tetrachloride affects the expression of RAD51AP1 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | ISO | RGD:1315620 | 6480464 | Carbon Tetrachloride results in increased expression of RAD51AP1 mRNA | CTD | PMID:31919559 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of RAD51AP1 mRNA | CTD | PMID:23411599 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of RAD51AP1 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | ISO | RGD:1315620 | 6480464 | Trichloroethylene results in increased expression of RAD51AP1 mRNA | CTD | PMID:25549359 | triclosan | decreases expression | ISO | RGD:1353541 | 6480464 | Triclosan results in decreased expression of RAD51AP1 mRNA | CTD | PMID:30510588 | trimellitic anhydride | increases expression | ISO | RGD:1315620 | 6480464 | trimellitic anhydride results in increased expression of RAD51AP1 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | RGD:1353541 | 6480464 | troglitazone results in decreased expression of RAD51AP1 mRNA | CTD | PMID:19140230 | urethane | decreases expression | ISO | RGD:1353541 | 6480464 | Urethane results in decreased expression of RAD51AP1 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | RGD:1353541 | 6480464 | Valproic Acid results in decreased expression of RAD51AP1 mRNA | CTD | PMID:28001369 | zinc dichloride | increases expression | ISO | RGD:1315620 | 6480464 | zinc chloride results in increased expression of RAD51AP1 mRNA | CTD | PMID:19000923 | |