Gene: Pcsk9 (proprotein convertase subtilisin/kexin type 9) Rattus norvegicus
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Symbol: Pcsk9
Name: proprotein convertase subtilisin/kexin type 9
Description: Predicted to have several functions, including lipoprotein particle binding activity, molecular function regulator, and signaling receptor binding activity; involved in several processes, including animal organ development, cellular response to insulin stimulus, and cellular response to starvation; localizes to the extracellular space and rough endoplasmic reticulum; orthologous to human PCSK9 (proprotein convertase subtilisin/kexin type 9); INTERACTS WITH 1,2-dimethylhydrazine; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: NARC-1; Narc1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; PC9; proprotein convertase 9; proprotein convertase PC9; subtilisin/kexin-like protease PC9
Orthologs:
Homo sapiens (human) : PCSK9 (proprotein convertase subtilisin/kexin type 9)  HGNC  Alliance
Mus musculus (house mouse) : Pcsk9 (proprotein convertase subtilisin/kexin type 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk9 (proprotein convertase subtilisin/kexin type 9)
Pan paniscus (bonobo/pygmy chimpanzee) : PCSK9 (proprotein convertase subtilisin/kexin type 9)
Canis lupus familiaris (dog) : PCSK9 (proprotein convertase subtilisin/kexin type 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk9 (proprotein convertase subtilisin/kexin type 9)
Sus scrofa (pig) : PCSK9 (proprotein convertase subtilisin/kexin type 9)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05126,031,368 - 126,053,726 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05129,878,797 - 129,900,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45127,501,476 - 127,524,289 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15127,507,768 - 127,529,490 (-)NCBI
Celera5119,960,965 - 119,983,199 (-)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pcsk9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 728909
Created: 2003-11-21
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.