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Gene: Hyls1 (HYLS1, centriolar and ciliogenesis associated) Rattus norvegicus
Symbol: Hyls1
Name: HYLS1, centriolar and ciliogenesis associated
Description: Predicted to be involved in cilium assembly. Predicted to localize to several cellular components, including the cytosol; microtubule organizing center; and non-motile cilium. Human ortholog(s) of this gene implicated in hydrolethalus syndrome. Orthologous to human HYLS1 (HYLS1 centriolar and ciliogenesis associated); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: hydrolethalus syndrome 1; hydrolethalus syndrome protein 1; hypothetical protein LOC680262; LOC680262
Homo sapiens (human) : HYLS1 (HYLS1 centriolar and ciliogenesis associated)  HGNC  Alliance
Mus musculus (house mouse) : Hyls1 (HYLS1, centriolar and ciliogenesis associated)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hyls1 (HYLS1 centriolar and ciliogenesis associated)
Pan paniscus (bonobo/pygmy chimpanzee) : HYLS1 (HYLS1 centriolar and ciliogenesis associated)
Canis lupus familiaris (dog) : HYLS1 (HYLS1 centriolar and ciliogenesis associated)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hyls1 (HYLS1 centriolar and ciliogenesis associated)
Sus scrofa (pig) : HYLS1 (HYLS1 centriolar and ciliogenesis associated)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0836,763,470 - 36,772,199 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0836,779,955 - 36,789,157 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4835,345,398 - 35,354,440 (-)NCBIRGSC3.4rn4RGSC3.4
Celera835,334,107 - 35,342,836 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Hyls1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1594169
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.