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Gene: Rrm1 (ribonucleotide reductase catalytic subunit M1) Rattus norvegicus
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Symbol: Rrm1
Name: ribonucleotide reductase catalytic subunit M1
Description: Predicted to have several functions, including disordered domain specific binding activity; identical protein binding activity; and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in several processes, including animal organ development; pyrimidine nucleobase metabolic process; and response to ionizing radiation. Localizes to several cellular components, including the cell projection; neuronal cell body; and nuclear envelope. Biomarker of visual epilepsy. Orthologous to human RRM1 (ribonucleotide reductase catalytic subunit M1); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC685579; MGC94742; ribonucleoside-diphosphate reductase large subunit; ribonucleotide reductase M1; similar to ribonucleotide reductase M1
Orthologs:
Homo sapiens (human) : RRM1 (ribonucleotide reductase catalytic subunit M1)  HGNC  Alliance
Mus musculus (house mouse) : Rrm1 (ribonucleotide reductase M1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rrm1 (ribonucleotide reductase catalytic subunit M1)
Pan paniscus (bonobo/pygmy chimpanzee) : RRM1 (ribonucleotide reductase catalytic subunit M1)
Canis lupus familiaris (dog) : RRM1 (ribonucleotide reductase catalytic subunit M1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rrm1 (ribonucleotide reductase catalytic subunit M1)
Sus scrofa (pig) : RRM1 (ribonucleotide reductase catalytic subunit M1)
Chlorocebus sabaeus (green monkey) : RRM1 (ribonucleotide reductase catalytic subunit M1)
Heterocephalus glaber (naked mole-rat) : Rrm1 (ribonucleotide reductase catalytic subunit M1)
more info ...
Related Pseudogenes: Rrm1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: NCBI's current annotation of the functional gene (chromosome 1) and a pseudogene (chromosome 14) are not consistent on all assemblies. The functional gene on the Celera assembly is currently annotated with the GeneID of the pseudogene on chromosome 14. [17 Jun 2014]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01167,538,387 - 167,562,688 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,538,263 - 167,562,688 (+)Ensembl
Rnor_5.01173,726,994 - 173,751,295 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41159,930,994 - 159,937,860 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1154,890,871 - 154,915,173 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rrm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1592569
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.