Cenpf (centromere protein F) - Rat Genome Database

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Gene: Cenpf (centromere protein F) Rattus norvegicus
Analyze
Symbol: Cenpf
Name: centromere protein F
RGD ID: 628667
Description: Predicted to enable several functions, including dynein complex binding activity; protein C-terminus binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including metaphase plate congression; regulation of G2/M transition of mitotic cell cycle; and ventricular system development. Predicted to act upstream of or within regulation of striated muscle tissue development. Predicted to be located in several cellular components, including cytoskeleton; midbody; and nucleus. Predicted to be part of ciliary transition fiber and outer kinetochore. Predicted to be active in chromosome, centromeric region; nucleus; and spindle pole. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: centromere autoantigen F; LEK/centromere protein; Lek1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213101,184,127 - 101,229,714 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)Ensembl
Rnor_6.013108,132,499 - 108,178,609 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013112,758,855 - 112,804,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413105,920,242 - 105,965,655 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113106,125,141 - 106,126,183 (-)NCBI
Celera13100,670,298 - 100,715,841 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(R)-mevalonic acid  (ISO)
1,1-dichloroethene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
choline  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cryptolepine  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dieldrin  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
etoposide  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
folpet  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glycidol  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
isobutanol  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
lithium chloride  (ISO)
lovastatin  (ISO)
lucanthone  (ISO)
malathion  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
miconazole  (ISO)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nickel dichloride  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP,ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
pinosylvin  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
SP2509  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trans-pinosylvin  (ISO)
tremolite asbestos  (ISO)
triazines  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family. Goodwin RL, etal., J Biol Chem 1999 Jun 25;274(26):18597-604.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7542657   PMID:7642639   PMID:7651420   PMID:7904902   PMID:9763420   PMID:11084331   PMID:12154071   PMID:12974617   PMID:15494374   PMID:15677469   PMID:15870278   PMID:16252009  
PMID:17363900   PMID:17600710   PMID:25564561   PMID:35527655  


Genomics

Comparative Map Data
Cenpf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213101,184,127 - 101,229,714 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)Ensembl
Rnor_6.013108,132,499 - 108,178,609 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013112,758,855 - 112,804,965 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413105,920,242 - 105,965,655 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113106,125,141 - 106,126,183 (-)NCBI
Celera13100,670,298 - 100,715,841 (-)NCBICelera
Cytogenetic Map13q26NCBI
CENPF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381214,603,195 - 214,664,571 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1214,603,195 - 214,664,571 (+)EnsemblGRCh38hg38GRCh38
GRCh371214,776,538 - 214,837,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361212,843,155 - 212,904,537 (+)NCBINCBI36hg18NCBI36
Build 341211,164,926 - 211,226,307NCBI
Celera1187,999,934 - 188,061,298 (+)NCBI
Cytogenetic Map1q41NCBI
HuRef1185,450,388 - 185,511,761 (+)NCBIHuRef
CHM1_11216,048,789 - 216,110,152 (+)NCBICHM1_1
T2T-CHM13v2.01213,842,449 - 213,903,796 (+)NCBI
Cenpf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391189,372,803 - 189,420,302 (-)NCBIGRCm39mm39
GRCm39 Ensembl1189,372,803 - 189,420,283 (-)Ensembl
GRCm381189,640,606 - 189,688,107 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1189,640,606 - 189,688,086 (-)EnsemblGRCm38mm10GRCm38
MGSCv371191,464,485 - 191,511,965 (-)NCBIGRCm37mm9NCBIm37
MGSCv361191,341,394 - 191,388,874 (-)NCBImm8
Celera1196,559,635 - 196,607,121 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map195.03NCBI
Cenpf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554063,223,993 - 3,273,714 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554063,225,788 - 3,273,037 (-)NCBIChiLan1.0ChiLan1.0
CENPF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11195,025,577 - 195,086,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1195,024,877 - 195,086,518 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01190,170,414 - 190,231,478 (+)NCBIMhudiblu_PPA_v0panPan3
CENPF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1712,558,455 - 12,618,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl712,555,143 - 12,617,996 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha712,129,485 - 12,194,142 (+)NCBI
ROS_Cfam_1.0712,265,629 - 12,330,197 (+)NCBI
ROS_Cfam_1.0 Ensembl712,265,609 - 12,328,372 (+)Ensembl
UMICH_Zoey_3.1712,188,652 - 12,253,247 (+)NCBI
UNSW_CanFamBas_1.0712,293,025 - 12,357,544 (+)NCBI
UU_Cfam_GSD_1.0712,421,098 - 12,482,469 (+)NCBI
Cenpf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934461,632,209 - 61,686,939 (-)NCBI
SpeTri2.0NW_0049366283,642,281 - 3,695,262 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CENPF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9128,948,498 - 129,012,218 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19128,948,386 - 129,012,241 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29141,675,880 - 141,740,104 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CENPF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12514,914,805 - 14,972,811 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2514,914,809 - 14,972,796 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605515,379,185 - 15,438,265 (-)NCBIVero_WHO_p1.0
Cenpf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477119,656,981 - 19,702,625 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462477119,657,489 - 19,702,506 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH143346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213101,190,612 - 101,190,778 (+)MAPPERmRatBN7.2
Rnor_6.013108,138,984 - 108,139,149NCBIRnor6.0
Rnor_5.013112,765,340 - 112,765,505UniSTSRnor5.0
RGSC_v3.413105,926,598 - 105,926,763UniSTSRGSC3.4
Celera13100,676,784 - 100,676,949UniSTS
RH 3.4 Map13692.9UniSTS
Cytogenetic Map13q27UniSTS
RH138998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213101,221,531 - 101,221,656 (+)MAPPERmRatBN7.2
Rnor_6.013108,170,472 - 108,170,596NCBIRnor6.0
Rnor_5.013112,796,828 - 112,796,952UniSTSRnor5.0
RGSC_v3.413105,957,518 - 105,957,642UniSTSRGSC3.4
RGSC_v3.42211,884,456 - 211,884,580UniSTSRGSC3.4
Celera13100,707,704 - 100,707,828UniSTS
RH 3.4 Map13691.8UniSTS
Cytogenetic Map13q27UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:147
Count of miRNA genes:111
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000004525
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 26 31 22 15 22 1 1 41 21 33 1 1
Low 2 14 20 13 4 13 3 3 19 12 8 10 3
Below cutoff 3 6 6 6 4 6 14 2 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000004525   ⟹   ENSRNOP00000004525
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13101,184,127 - 101,229,669 (-)Ensembl
Rnor_6.0 Ensembl13108,132,499 - 108,178,609 (-)Ensembl
RefSeq Acc Id: NM_001100827   ⟹   NP_001094297
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213101,184,127 - 101,229,669 (-)NCBI
Rnor_6.013108,132,499 - 108,178,609 (-)NCBI
Rnor_5.013112,758,855 - 112,804,965 (-)NCBI
RGSC_v3.413105,920,242 - 105,965,655 (-)RGD
Celera13100,670,298 - 100,715,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090398   ⟹   XP_038946326
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213101,184,127 - 101,229,714 (-)NCBI
RefSeq Acc Id: XM_039090399   ⟹   XP_038946327
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213101,184,127 - 101,229,478 (-)NCBI
RefSeq Acc Id: XM_039090400   ⟹   XP_038946328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213101,184,127 - 101,229,714 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001094297 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946326 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946327 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946328 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK53814 (Get FASTA)   NCBI Sequence Viewer  
  EDL94964 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001094297   ⟸   NM_001100827
- Sequence:
RefSeq Acc Id: ENSRNOP00000004525   ⟸   ENSRNOT00000004525
RefSeq Acc Id: XP_038946328   ⟸   XM_039090400
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038946326   ⟸   XM_039090398
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038946327   ⟸   XM_039090399
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699104
Promoter ID:EPDNEW_R9629
Type:multiple initiation site
Name:Cenpf_1
Description:centromere protein F
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013108,178,604 - 108,178,664EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628667 AgrOrtholog
BioCyc Gene G2FUF-16901 BioCyc
Ensembl Genes ENSRNOG00000003388 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004525 ENTREZGENE
  ENSRNOP00000004525.7 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004525 ENTREZGENE
  ENSRNOT00000004525.7 UniProtKB/TrEMBL
InterPro Cenp-F UniProtKB/TrEMBL
  Centromere_CenpF_leu-rich_rpt UniProtKB/TrEMBL
  Centromere_CenpF_N UniProtKB/TrEMBL
  Centromere_CenpF_Rb-prot-bd UniProtKB/TrEMBL
NCBI Gene 257649 ENTREZGENE
PANTHER PTHR18874 UniProtKB/TrEMBL
Pfam Cenp-F_leu_zip UniProtKB/TrEMBL
  Cenp-F_N UniProtKB/TrEMBL
  Rb-bdg_C_Cenp-F UniProtKB/TrEMBL
PhenoGen Cenpf PhenoGen
UniProt E9PT83_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-25 Cenpf  centromere protein F  Cenpf  centromere autoantigen F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cenpf  centromere autoantigen F  Lek1  LEK/centromere protein  Symbol and Name updated 1299863 APPROVED
2003-02-27 Lek1  LEK/centromere protein      Symbol and Name status set to provisional 70820 PROVISIONAL