Chd2 (chromodomain helicase DNA binding protein 2) - Rat Genome Database

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Gene: Chd2 (chromodomain helicase DNA binding protein 2) Rattus norvegicus
Analyze
Symbol: Chd2
Name: chromodomain helicase DNA binding protein 2
RGD ID: 1310056
Description: Predicted to enable several functions, including ATP hydrolysis activity; ATP-dependent chromatin remodeler activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in gene expression; muscle organ development; and nucleosome organization. Predicted to act upstream of or within DNA damage response and hematopoietic stem cell differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 94. Orthologous to human CHD2 (chromodomain helicase DNA binding protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chromodomain-helicase-DNA-binding protein 2; LOC108349594; LOC308738; uncharacterized LOC108349594
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81136,597,993 - 136,726,874 (-)NCBIGRCr8
mRatBN7.21127,188,146 - 127,317,041 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1127,190,059 - 127,300,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,179,350 - 135,289,183 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01142,349,455 - 142,459,293 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,177,391 - 135,286,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,757,934 - 134,873,053 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,757,934 - 134,871,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,782,462 - 135,897,354 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,609,727 - 128,720,325 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11128,688,083 - 128,798,804 (-)NCBI
Celera1119,322,047 - 119,431,932 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
chrysene  (ISO)
clobetasol  (ISO)
clotrimazole  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
Enterolactone  (ISO)
erythromycin estolate  (EXP)
fenthion  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glucose  (ISO)
hydralazine  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
nicotine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thiram  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (IBA)
nucleus  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19137022   PMID:22569126   PMID:22658674   PMID:22681889   PMID:23376485  


Genomics

Comparative Map Data
Chd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81136,597,993 - 136,726,874 (-)NCBIGRCr8
mRatBN7.21127,188,146 - 127,317,041 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1127,190,059 - 127,300,502 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,179,350 - 135,289,183 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01142,349,455 - 142,459,293 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01135,177,391 - 135,286,853 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01134,757,934 - 134,873,053 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,757,934 - 134,871,167 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,782,462 - 135,897,354 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41128,609,727 - 128,720,325 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11128,688,083 - 128,798,804 (-)NCBI
Celera1119,322,047 - 119,431,932 (-)NCBICelera
Cytogenetic Map1q31NCBI
CHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381592,900,324 - 93,027,996 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1592,886,203 - 93,027,996 (+)EnsemblGRCh38hg38GRCh38
GRCh371593,443,554 - 93,571,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361591,244,555 - 91,372,241 (+)NCBINCBI36Build 36hg18NCBI36
Build 341591,244,422 - 91,366,396NCBI
Celera1569,855,404 - 69,982,772 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1569,580,061 - 69,707,674 (+)NCBIHuRef
CHM1_11593,284,562 - 93,411,895 (+)NCBICHM1_1
T2T-CHM13v2.01590,662,587 - 90,790,268 (+)NCBIT2T-CHM13v2.0
Chd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39773,076,400 - 73,191,494 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl773,076,386 - 73,191,578 (-)EnsemblGRCm39 Ensembl
GRCm38773,426,652 - 73,541,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl773,426,638 - 73,541,830 (-)EnsemblGRCm38mm10GRCm38
MGSCv37780,571,538 - 80,686,632 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36773,303,121 - 73,415,343 (-)NCBIMGSCv36mm8
Celera770,874,423 - 70,989,778 (-)NCBICelera
Cytogenetic Map7D1NCBI
cM Map741.85NCBI
Chd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541621,085,570 - 21,210,321 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541621,085,570 - 21,210,321 (+)NCBIChiLan1.0ChiLan1.0
CHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21682,430,058 - 82,574,809 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11586,128,120 - 86,272,854 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01571,568,560 - 71,713,330 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11590,780,220 - 90,906,863 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1590,781,169 - 90,903,569 (+)Ensemblpanpan1.1panPan2
CHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,101,789 - 47,221,473 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,105,046 - 47,221,385 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha349,802,181 - 49,921,599 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0347,511,193 - 47,631,121 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl347,511,205 - 47,631,054 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1347,029,130 - 47,148,452 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0347,260,475 - 47,380,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0347,591,992 - 47,711,357 (-)NCBIUU_Cfam_GSD_1.0
Chd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640136,403,356 - 136,530,590 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364839,803,623 - 9,931,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364839,803,887 - 9,931,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl785,983,837 - 86,106,938 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1785,980,759 - 86,107,886 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2791,874,318 - 92,002,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12911,436,170 - 11,579,468 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2911,450,799 - 11,579,594 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605935,081,933 - 35,228,711 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476810,785,815 - 10,922,790 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476810,786,139 - 10,922,558 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chd2
579 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:51
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000055829
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
631570Bp94Blood pressure QTL 940.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123479780142990467Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
61346Rf2Renal disease susceptibility QTL 23.7urine protein amount (VT:0005160)urine protein level (CMO:0000591)199267916144267916Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1102268556147268556Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847151047847Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2303591Gluco41Glucose level QTL 412blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1102168504147168504Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)199267916144267916Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1103111621148111621Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1102813953151162766Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
2325726Eae30Experimental allergic encephalomyelitis QTL 30nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1123053310128593844Rat

Markers in Region
RH143573  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21127,301,816 - 127,301,962 (+)MAPPERmRatBN7.2
Rnor_6.01134,872,486 - 134,872,631NCBIRnor6.0
Rnor_5.01135,896,784 - 135,896,929UniSTSRnor5.0
RGSC_v3.41128,721,643 - 128,721,788UniSTSRGSC3.4
Celera1119,433,250 - 119,433,395UniSTS
RH 3.4 Map1994.1UniSTS
Cytogenetic Map1q31UniSTS
AW535385  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21127,205,413 - 127,205,607 (+)MAPPERmRatBN7.2
Rnor_6.01134,775,197 - 134,775,390NCBIRnor6.0
Rnor_5.01135,799,725 - 135,799,918UniSTSRnor5.0
RGSC_v3.41128,624,096 - 128,624,289UniSTSRGSC3.4
Celera1119,336,416 - 119,336,609UniSTS
RH 3.4 Map1984.0UniSTS
Cytogenetic Map1q31UniSTS
RH141602  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21127,298,650 - 127,298,841 (+)MAPPERmRatBN7.2
Rnor_6.01134,869,319 - 134,869,509NCBIRnor6.0
Rnor_5.01135,893,617 - 135,893,807UniSTSRnor5.0
RGSC_v3.41128,718,476 - 128,718,666UniSTSRGSC3.4
Celera1119,430,083 - 119,430,273UniSTS
RH 3.4 Map1974.5UniSTS
Cytogenetic Map1q31UniSTS
MARC_17499-17500:1016469992:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21127,242,417 - 127,243,007 (+)MAPPERmRatBN7.2
Rnor_6.01134,813,025 - 134,813,614NCBIRnor6.0
Rnor_5.01135,837,553 - 135,838,142UniSTSRnor5.0
RGSC_v3.41128,661,098 - 128,661,687UniSTSRGSC3.4
Celera1119,373,414 - 119,374,003UniSTS
Cytogenetic Map1q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000055829   ⟹   ENSRNOP00000052684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1127,190,299 - 127,296,642 (-)Ensembl
Rnor_6.0 Ensembl1134,760,842 - 134,870,255 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1134,883,619 - 134,885,774 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1134,873,400 - 134,887,841 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076300   ⟹   ENSRNOP00000068303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1127,190,059 - 127,300,502 (-)Ensembl
Rnor_6.0 Ensembl1134,757,934 - 134,871,167 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1134,873,408 - 134,887,403 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1134,873,469 - 134,885,613 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090149   ⟹   ENSRNOP00000075309
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1127,190,299 - 127,296,642 (-)Ensembl
Rnor_6.0 Ensembl1134,760,084 - 134,867,001 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098073   ⟹   ENSRNOP00000085288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1127,190,059 - 127,300,502 (-)Ensembl
RefSeq Acc Id: NM_001107523   ⟹   NP_001100993
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,600,887 - 136,710,335 (-)NCBI
mRatBN7.21127,191,045 - 127,300,500 (-)NCBI
Rnor_6.01134,760,828 - 134,871,168 (-)NCBI
Rnor_5.01135,782,462 - 135,897,354 (-)NCBI
RGSC_v3.41128,609,727 - 128,720,325 (-)RGD
Celera1119,322,047 - 119,431,932 (-)RGD
Sequence:
RefSeq Acc Id: XM_039112837   ⟹   XP_038968765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
mRatBN7.21127,191,045 - 127,317,041 (-)NCBI
RefSeq Acc Id: XM_039112868   ⟹   XP_038968796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
mRatBN7.21127,191,045 - 127,317,041 (-)NCBI
RefSeq Acc Id: XM_039112875   ⟹   XP_038968803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,661,486 (-)NCBI
mRatBN7.21127,188,146 - 127,251,648 (-)NCBI
RefSeq Acc Id: XM_063262604   ⟹   XP_063118674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262608   ⟹   XP_063118678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,619 (-)NCBI
RefSeq Acc Id: XM_063262609   ⟹   XP_063118679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,725,614 (-)NCBI
RefSeq Acc Id: XM_063262621   ⟹   XP_063118691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262625   ⟹   XP_063118695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262626   ⟹   XP_063118696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262627   ⟹   XP_063118697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,597,993 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262629   ⟹   XP_063118699
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,606,311 - 136,726,874 (-)NCBI
RefSeq Acc Id: XM_063262631   ⟹   XP_063118701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,667,155 - 136,726,874 (-)NCBI
RefSeq Acc Id: XR_010052226
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,625,182 - 136,726,874 (-)NCBI
RefSeq Acc Id: XR_010052231
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,640,913 - 136,726,874 (-)NCBI
RefSeq Acc Id: XR_010052232
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81136,646,034 - 136,726,874 (-)NCBI
RefSeq Acc Id: NP_001100993   ⟸   NM_001107523
- UniProtKB: A0A096MJY0 (UniProtKB/TrEMBL),   A6JBX9 (UniProtKB/TrEMBL),   D4AD08 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052684   ⟸   ENSRNOT00000055829
Ensembl Acc Id: ENSRNOP00000075309   ⟸   ENSRNOT00000090149
Ensembl Acc Id: ENSRNOP00000068303   ⟸   ENSRNOT00000076300
RefSeq Acc Id: XP_038968803   ⟸   XM_039112875
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038968796   ⟸   XM_039112868
- Peptide Label: isoform X6
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968765   ⟸   XM_039112837
- Peptide Label: isoform X2
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085288   ⟸   ENSRNOT00000098073
RefSeq Acc Id: XP_063118696   ⟸   XM_063262626
- Peptide Label: isoform X4
- UniProtKB: D4AD08 (UniProtKB/TrEMBL),   A0A8I6GCU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118695   ⟸   XM_063262625
- Peptide Label: isoform X3
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118697   ⟸   XM_063262627
- Peptide Label: isoform X5
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118674   ⟸   XM_063262604
- Peptide Label: isoform X1
- UniProtKB: D4AD08 (UniProtKB/TrEMBL),   A0A0G2KA92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118691   ⟸   XM_063262621
- Peptide Label: isoform X2
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118678   ⟸   XM_063262608
- Peptide Label: isoform X1
- UniProtKB: D4AD08 (UniProtKB/TrEMBL),   A0A0G2KA92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118679   ⟸   XM_063262609
- Peptide Label: isoform X1
- UniProtKB: D4AD08 (UniProtKB/TrEMBL),   A0A0G2KA92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118699   ⟸   XM_063262629
- Peptide Label: isoform X7
- UniProtKB: D4AD08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118701   ⟸   XM_063262631
- Peptide Label: isoform X9
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2KA92-F1-model_v2 AlphaFold A0A0G2KA92 1-1840 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690116
Promoter ID:EPDNEW_R639
Type:multiple initiation site
Name:Chd2_2
Description:chromodomain helicase DNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R640  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01134,867,098 - 134,867,158EPDNEW
RGD ID:13690117
Promoter ID:EPDNEW_R640
Type:multiple initiation site
Name:Chd2_1
Description:chromodomain helicase DNA binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R639  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01134,871,167 - 134,871,227EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310056 AgrOrtholog
BioCyc Gene G2FUF-58893 BioCyc
Ensembl Genes ENSRNOG00000012716 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000051039 Ensembl
Ensembl Transcript ENSRNOT00000055829.4 UniProtKB/TrEMBL
  ENSRNOT00000076300.3 UniProtKB/TrEMBL
  ENSRNOT00000090149.2 UniProtKB/TrEMBL
  ENSRNOT00000098073.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1440 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro CDH1_2_SANT_HL1 UniProtKB/TrEMBL
  Chromo_domain UniProtKB/TrEMBL
  Chromo_domain/shadow UniProtKB/TrEMBL
  Chromodomain-like UniProtKB/TrEMBL
  Chromodomain_CS UniProtKB/TrEMBL
  DUF4208 UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
KEGG Report rno:308738 UniProtKB/TrEMBL
NCBI Gene 308738 ENTREZGENE
PANTHER CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 2 UniProtKB/TrEMBL
  CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED UniProtKB/TrEMBL
Pfam CDH1_2_SANT_HL1 UniProtKB/TrEMBL
  Chromo UniProtKB/TrEMBL
  DUF4208 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  SNF2_N UniProtKB/TrEMBL
PhenoGen Chd2 PhenoGen
PROSITE CHROMO_1 UniProtKB/TrEMBL
  CHROMO_2 UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012716 RatGTEx
  ENSRNOG00000051039 RatGTEx
SMART CHROMO UniProtKB/TrEMBL
  DEXDc UniProtKB/TrEMBL
  DUF4208 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP Chromodomain-like UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A096MJY0 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KA92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GCU8 ENTREZGENE, UniProtKB/TrEMBL
  A6JBX9 ENTREZGENE, UniProtKB/TrEMBL
  D4AD08 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Chd2  chromodomain helicase DNA binding protein 2  LOC108349594  uncharacterized LOC108349594  Data merged from RGD:11468822 737654 PROVISIONAL
2016-08-02 LOC108349594  uncharacterized LOC108349594      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Chd2  chromodomain helicase DNA binding protein 2   Chd2_predicted  chromodomain helicase DNA binding protein 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Chd2_predicted  chromodomain helicase DNA binding protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED